Turn-ons and turn-offs for neurons
...asan and colleagues at the Max Planck Institute for Medical Research in Heidelberg have therefore systematically examined individual components of the tet systems and delineated the necessary conditions for reversible control of gene expression in neurons. In the June 20th issue of the online, open-...Novel live reporting system to track cells
...ferritin sensitive to tetracycline (TET), a common antibiotic, so that when tet is present, the ferritin is "off" and when tet is absent, ferritin is "on." Tumor cells with modified ferritin were insert...Clontech Laboratories, Inc. Releases the ProteoTuner(TM) Systems
...and the Knockout(TM) RNAi systems for mRNA knockdown. Each of these three systems has particular, complementary strengths: the tight regulation of the tet systems, Knockout RNAi's excellent control of endogenous protein levels, and the fast control of protein levels via the ProteoTuner systems. Each can ...Mx4000 Multiplex Quantitative PCR System*,PPP
... to block out unwanted cross-talk from spectrally adjacent fluorophores. Researchers can choose from FAM, HEX, TAMRA, Cy5, Cy3, Texas Red/ROX, and tet filter sets. Custom filter sets are also available for other fluorophores. Detect Up to Four Fluorophores in the Same Tube ...Brilliant Core Reagent Kits for QPCR and QRT-PCR
...as complementary to the mutant allele (A), and the tet probe was complementary to the wild-typ... sample containing the wild-type alleles only, the tet signal should be relatively strong and ... 3 ). In the case of a heterozygote, both FAM and tet signals should be seen, but the Ct valu...Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits
...stinguished simultaneously by the type of fluorescence detected: tet fluorescence indicates homozygosity for the wild-type allele, FAM fluorescence indicates homozygosity for the mutant allele, and both tet and FAM fluorescence together indicates heterozygosity ( Figure ...