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Testes in Medical News

Stem Cells From Testes Produce Wide Range of Tissue Types

Work with mice might lead to treatments for diseases such as diabetes and Alzheimer's WEDNESDAY, Sept. 19 (HealthDay News) -- U.S. researchers say they've successfully reprogrammed adult stem cells from the testes of male mice into a wide variety of cell types, including functional blood vessels...

Stem cells derived from adult testes produce wide range of tissue types

After a decade of research, Howard Hughes Medical Institute scientists have succeeded in reprogramming adult stem cells from the testes of male mice into functional blood vessels and contractile cardiac tissue. The research offers a promising new source of stem cells for use in organ regeneration ...

Stem cells in adult testes provide alternative to embryonic stem cells for organ regeneration

NEW YORK (Sept. 20, 2007) -- Easily accessed and plentiful, adult stem cells found in a male patient's testicles might someday be used to create a wide range of tissue types to help him fight disease -- getting around the need for more controversial embryonic stem cells. That's the promise of a...

Researchers Create Embryonic-Like Stem Cells From Human Testes

Finding could sidestep ethical concerns surrounding use of cells from embryos WEDNESDAY, Oct. 8 (HealthDay News) -- European researchers say they've figured out how to coax sperm-producing testicular cells into embryonic-like stem cells. The findings are the latest in a flurry of pu...

German Scientists Create Stem Cells From Mouse Testes

German Scientists claim to have transformed testicular cells obtained from male mice into embryonic stem cells//, biological building blocks that have the remarkable ability to transform into other cell types. This research led to the belief the same could be achieved in humans, helping set...

Researchers clone key sperm-binding proteins

...ates and rodents. According to Dr.Manjunath and his team, these species produce small amounts of BSPs only in the epididymis, a duct that connects the testes to the urethra. "For a few years, we were looking in the wrong place," says Dr. Manjunath. "In addition, the minute quantities of BSP produced in h...

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive

... first time a specific "niche factor" in the mouse testes called colony stimulating factor 1, Csf1, that has...s growth factor is the Leydig cell located in the testes and stimulated by the pituitary gland to supply te...ermatogenesis and production of spermatozoa in the testes of adult males, whether man or mouse. The SSCs' se...

Marijuana Linked to Aggressive Testicular Cancer

...e or more external factors, including a simultaneous and comparable rise in the use of marijuana. Along those lines, the researchers noted that the testes could be particularly vulnerable to the effects of marijuana, given that the organ -- along with the brain, heart, uterus and spleen -- carries specif...

Marijuana use linked to increased risk of testicular cancer

...ealth Sciences Division at the Hutchinson Center. Established risk factors for testicular cancer include a family history of the disease, undescended testes and abnormal testicular development. The disease is thought to begin in the womb, when some fetal germ cells (those that eventually make sperm in adul...

The Obama Cancer Plan Should Prioritize Prevention, Says Cancer Prevention Coalition

... statistics. These show increases of 45% for thyroid cancer, 18% for malignant melanoma, 18% for kidney cancer, 10% for childhood cancers, and 4% for testes cancer. Disturbingly, the NCI has still failed to develop, let alone publicize, any listing or registry of avoidable exposures to a wide range ...
Testes in Medical Technology

Repros' Proellex Shows Statistically Significant Improvement in Primary Endpoint in Phase 2 Trial in the Treatment of Uterine Fibroids

... U.S. and Canada. Androxal(TM), the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes and is being tested in a non-pivotal U.S. Phase 3 clinical trial for the treatment of testosterone deficiency in men due to secondary hypogonadism. ...

Repros' Androxal Shows Highly Statistically Significant Positive Effects in Men with Secondary Hypogonadism

... the U.S. and Canada. Androxal, the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes and has completed a six month U.S. Phase 3 clinical trial for the treatment of testosterone deficiency in men due to secondary hypogonadism. According...

Repros Reports That Proellex Has Demonstrated Superior Efficacy and Safety in Endometriosis When Compared to Standard of Drug Care

...tates and Canada. Androxal(TM), the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes in men and has recently completed a six-month U.S. non-pivotal Phase 3 clinical trial for the treatment of testosterone deficiency due to secondary hy...

Peer Reviewed Journal Article Indicates Repros' Proellex Exhibits Potential for New Approach to the Treatment and Prevention of Breast Cancer

...tates and Canada. Androxal(TM), the Company's other program in late clinical development, is designed to restore normal testosterone production by the testes and has recently completed a six-month U.S. non-pivotal Phase 3 clinical trial for the treatment of testosterone deficiency in men due to secondary hy...
Testes in Medical Products

Testosterone RIA Test

Description:...ne-3-one), a C19 steroid, is one of the most potent naturally secreted androgens [1]. In postpubertal males, testosterone is secreted primarily by the testes with only a small amount derived from peripheral conversion of androstenedione [2]. In adult women, it has been estimated that over 50% of serum testo...
Company:Diagnostic Systems Laboratories, Inc.

Progesterone EIA Test

Description:...sterone is a steroid produced by the adrenal cortex, the corpus luteum, the testes and the placenta. As with other steroids, progesterone is synthesized from ...nzyme-mediated steps [1,2]. Progesterone produced by the adrenal cortex and testes is almost immediately shunted into other steroidogenic pathways, with only ...
Company:Diagnostic Systems Laboratories, Inc.

Progesterone RIA Test

Description:...sterone is a steroid produced by the adrenal cortex, the corpus luteum, the testes and the placenta. As with other steroids, progesterone is synthesized from ...nzyme-mediated steps [1,2]. Progesterone produced by the adrenal cortex and testes is almost immediately shunted into other steroidogenic pathways, with only ...
Company:Diagnostic Systems Laboratories, Inc.

Testosterone EIA Test

Description:...ne-3-one), a C19 steroid, is one of the most potent naturally secreted androgens [1]. In postpubertal males, testosterone is secreted primarily by the testes with only a small amount derived from peripheral conversion of androstenedione [2]. In adult women, it has been estimated that over 50% of serum testo...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol, Ultra-Sensitive RIA Test

Description:...en derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of epiphyseal...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol RIA Test

Description:...en derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of epiphyseal...
Company:Diagnostic Systems Laboratories, Inc.

Estradiol EIA Test

Description:...en derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of epiphyseal...
Company:Diagnostic Systems Laboratories, Inc.

3rd Generation Estradiol RIA Test

Description:...en derived from androstenedione. Estrone and estradiol are interconverted in many body tissues. In men, small amounts of estradiol are produced in the testes and from peripheral conversion of androgens. The biological actions of estradiol include stimulation of linear bone growth, acceleration of epiphyseal...
Company:Diagnostic Systems Laboratories, Inc.
Testes in Medical Dictionary

Testes

Androgen insensitivity syndrome (AIS), also referred to as androgen resistance syndrome, is a set of disorders of sex development caused by mutations of the gene encoding the androgen receptor. The nature of the resulting... Human ectopic xenografting was performed using adult testes...

Undescended testicle

... Cryptorchidism is the absence of one or both testes from the scrotum. This usually represents failure of the testis to move, or "descend," during fetal development from an abdominal posit...

Testosterone

...mals, testosterone is primarily secreted in the testes of males and the ovaries of females, although sma...ormone, C 19 H 28 O 2 , produced primarily in the testes and responsible for the development and Test...minant male sex hormone that is produced by the testes ... testosterone supplement for low testos...

Testicular infection

... inflammation and immune factors on testicular function. ... detail, the course of testicular events during a bacterial infection . ... testes (Testicle, Testicular , Testis) articles, Information and Resources ... [ Testicular Infection (Epididymitis)] (Sexually Transmitted Disease (STD...

Sterility

... Sterility , permanent inability to produce offspring. Sterility can be caused by improper functioning of the sex organs, which in humans are the testes Vasectomy does not result in immediate sterilization. Male sterilization is confirmed through at ... www.urologychannel.com/vasecto my/ sterility ...

Sertoli

...y in Vienna under Ernst... The Sertoli cells, which are located in the male reproductive glands (the testes) ... In men, some cancers of the testes can start in the Sertoli and Leydig cells. ... A.G. Ferrari Foods ... Conti Sertoli Salis The Valtellina, along with the Mosel in Germany and...

Scrotum

...rd Lewis Sings And Chats About Scrotums On The View. ... teste palpable at birth and it still is not present in the scrotum . ... Locate the testes and bring into the scrotum (orchiopexy) or remove atrophic tissue. ... Normally, they descend into the scrotum before birth. ... The undesce...

Scrotal swelling

...e where the swelling is occurring. ... The causes of scrotal swelling in the stallion can be bifurcated into disorders of ... insult to the testes may also lead to testicular and/or scrotal swelling . ... ... 36 disease causes of Scrotal swelling , patient stories, diagnostic guide...

Precocious puberty

...is a form of precocious puberty that is not triggered by ... Precocious puberty occurs when the pituitary gland signals the ovaries and testes to mature too ... precocious puberty will be done. ... The main causes of precocious puberty are structural problems in the brain and ......

Posterior

... Posterior urethral valves (or PUV) are an abnormality of the urethra, which is ... Posterior Urethral Valves (PUV) Testicular Torsion. Undescended testes ... ... girdle.1 Anterior sternoclavicular dislocations outnumber posterior dislocations ... The diagnosis of a posterior sternoclavicular ...
Testes in Biological News

Human adult testes cells can become embryonic-like

WASHINGTON, D.C. Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent embryonic-like stem cells. Researchers say that the nave cells are now potentially ...

Stem cell chicken and egg debate moves to unlikely arena: the testes

LA JOLLA, CA Logic says it has to be the niche. As air and water preceded life, so the niche, that hospitable environment that shelters adult stem cells in many tissues and provides factors necessary to keep them young and vital, must have emerged before its stem cell dependents. A team of sc...

Female embryonic sexual development driven by universal factor

...he Y chromosome) that appeared to be essential for testes formation. But when researchers discovered some rare cases of individuals who developed testes even though they had two X chromosomes and no Y ch...ry, called the "Z" hypothesis, which proposed that testes development was actually the default pathway. Acco...

October 2008 Biology of Reproduction highlights

... Because the CKO mice exhibited transient fertility, an elegant reporter strategy was used to demonstrate that elongated spermatids present in the CKO testes did express the Cre recombinase; therefore, it is likely that differentiation to this stage can occur in the absence of DICER1. Nonetheless, Dicer1 ...

New study points to agriculture in frog sexual abnormalities

...ts have found that toads in suburban areas are less likely to suffer from reproductive system abnormalities than toads near farms where some had both testes and ovaries. "As you increase agriculture," said Lou Guillette, a distinguished professor of zoology, "you have an increasing number of abnormalit...

Eliminating germline lengthens fly lifespan, Brown study shows

...e team found a possible explanation for the paradox. In reaction to the flies brains boosting insulin production, the insects gonads their ovaries or testes produce a protein that acts like a sponge, binding to the insulin and blocking its signals throughout the body. So the flies respond as if there is l...

Armed beetles find a mate, whatever their size

...eeding sites with the big males, and attempt sneaky matings with females behind the bigger males backs. Whats more, these males have relatively larger testes and produce sperm that is more competitive than the bigger males. The L. japonicus beetles have ensured that, through their size-determined mating ...

Safeway Inc. and PCF to fund landmark prostate cancer research collaboration

...cancer begins in the testes, which are a few degrees cooler than the rest of the body. The structural machinery of cancer cells spreading outside the testes may be altered by the higher body temperatures, making them more susceptible to standard chemotherapy treatments than other cancer types. While hea...

Vaginal reconstruction not needed for most inter-sex females, Hopkins study shows

... Women with complete androgen insensitivity are born with relatively shallow vaginas that may or may not require surgical repair and with undescended testes that do require removal. Vaginal surgery, if needed or wanted, should be done after puberty, when physical development is complete and a girl or a...

Penn Veterinary Medicine report new strategy to create genetically-modified animals

...sted from experimentally induced cryptorchid donor testes that were then exposed in vitro to AAV vectors car...testes, resulting in colonization of the recipient testes by transgenic donor cells. When researchers mat...iation. Transgenic germ cells colonized recipient testes and produced transgenic sperm. When semen was use...
Testes in Biological Technology

New Report Just Published: World Prostate Cancer Therapeutics Market Report

...hites by Cancer Type in the US, 2000- 2004 (includes corresponding Graph/Chart) II-18 Prostate - Structure II-18 Pituitary Gland II-19 testes II-19 Prostate Cancer - A Primer II-20 Key Facts to Gaze at II-20 Table 13: Lifetime Probability of Developing Cancer (in Men) by Typ...

RT-PCR Primers for the Study of Apoptosis

...DNA library generated a PCR product larger in size than expected (lane 4). This may be a spliced version of Fas antigen found in testes or an artifact. Again, the amplification of the rat Fas antigen gene is specific. No band appeared on the control lanes with mouse and ...
Testes in Biological Definition

Klinefelter's syndrome

...drome is characterised by gynecomastia (enlarged breasts), a rounded body type with abnormal body proportions, sparse facial and body hair , small testes , and an inability to produce sperm . Most XXY males have some degree of language impairment as well. The syndrome is associated with an increased ri...

Semen

... 5 References 6 External links Composition Around 200 million to 500 million spermatozoa (or 'sperm', for short), produced in the testes , are released per ejaculation. However, they make up only about 2–5% of the volume of semen. The bulk of the semen is composed of seminal plasm...

Sperm

...rized by a minimum of cytoplasm. Sperm production Main article: Spermatogenesis Sperm are produced in the seminiferous tubules of the testes in a process called spermatogenesis. Round cells called spermatogonia divide and differentiate eventually to become sperm. During sexual intercourse...

Spermatogenesis

...tion, or genesis, of sperm cells, which occurs in the male gonads or testes . Sperm cells develop initially from germ stem cells known as spermatogoni... is maintained. Spermatozoa are produced in seminiferous tubules in the testes . They start off as spermatogonia , undergoing mitosis becoming a type A ...
Testes in Biological Dictionary

Testes

4.2 Diseases and conditions that affect the testes . 4.3 Effects of exogenous hormones ... Lymphatic drainage of the testes follows the testicular arteries back to the ... testicle n. A testis, especially one contained within a scrotum. ... 4.2 Diseases and conditions that affect the ...

Urethra

...noma ... The urinary tract is made up of the kidneys, the ureters, the bladder, and the urethra . The male reproductive tract includes the penis, testes (testicles). The ... ... of cancer of the urethra . Anterior urethral cancer. Posterior ... How cancer of the urethra is treated. Treatment...

Spermatids

... their permissiveness in ... Round spermatids , characterized by their small size as well as a centrally ... ... spermatids was observed in the testes from rats in which ... Key words: Pachytene spermatids , round spermatids , developing rat testis, spermatogenic arrest ... Classification of S...

Seminiferous tubules

...erences reproductive function ( in animal reproductive system: Testes; In anurans, amniotes (reptiles, birds, and mammals), and even some teleosts, testes are composed largely of seminiferous tubules—coiled tubes, the walls of which contain cells that... At the forefront of medicine, Gene Therapy...

Scrotum

...he penis and anus. In humans and some other mammals, the base of the... scrotum n. , pl. -ta or -tums . The external sac of skin enclosing the testes in ... The skin of the scrotum is exceptionally thin and beset with thinly ... The cause of an acute scrotum can usually be established based ...

Ovary

...an ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in females are homologous to testes in males, in that they are both gonads and endocrine... In the flowering plants, an ovary is a part of the female reproductive organ of the ...

Inverted Repeats

... - Inverted Repeats Finder. Please ... " Inverted Repeat Structure of the Human Genome: ... Highly Homologous Inverted Repeats That Contain testes Genes" ... Inverted Repeats Database (IRDB) is a public repository of information on ... These currently include, the Inverted Repeats Find...

Interstitial cells

...kipedia, the free encyclopedia. Jump to: navigation, search. Interstitial cells may refer to: Leydig cells , cells present in the male testes ... interstitial adj. Relating to, occurring in, or affecting interstices. Anatomy. Relating to or situated ... and surrounds the cells of mul...

Gonads

...The gonad is the organ that makes gametes. The gonads in males are the testes and the gonads in females are the ovaries. The product, gametes, are ha...s a part of the development of reproductive system and ultimately forms the testes Gonads are the true sex organs, generating reproductive gametes cont...
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