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Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

To ignite a life-threatening infection in the body, a virus such as HIV invades body cells by first merging, or fusing, with the cell's outer membrane. Once inside the cell, the invading microbe's genetic material takes over, turning the 'host' cell into a factory to produce more copies of the virus, which then spill out to invade other cells in the body. Scientists had assumed that once a...

HIV accessory protein disables host immunity via receptor-protein intermediary

Researchers at the University of Pennsylvania School of Medicine discovered that an HIV-1 accessory protein called Vpr destroys the host cell's ability to survive by binding to a host receptor. This, in turn, keeps an important enzyme from activating the cell's immune system. These findings refine an earlier understanding of Vpr HIV pathogenesis and imply new approaches to treating AIDS, inflamma...
Termed at Biology Products

Rabbit Anti-Evolutionarily conserved signaling intermediate in Toll pathway Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description:Evolutionarily conserved signaling intermediate in Toll pathway...
Company:GenWay Biotech, Inc.
Termed at Biology Technology

Analyzing Trace-Level Impurities of a Pharmaceutical Intermediate Using an LCQ Deca Ion Trap Mass Spectrometer and the Mass Frontier Software Package

Mark R. Kagan , Carrie Liu 1Thermo Finnigan, Piscataway, NJ; 2Thermo Finnigan, San Jose, CA; 3Eisai Research Institute, Andover, MA The data presented here can be a...
Termed at Biology Definition

Intermediate filament

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Termed at Biology Dictionary

Intermediate filament

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Termed at Medicine News

Slow Suffocation of Poultry Termed Inhumane

Animal welfare campaigners have termed the plans for slow suffocation of millions of poultry, in the event of a bird flu outbreak as inhumane//. According to Compassion in World Farming (CIWF) the Welfare of Animals (Slaughter and Killing) regulations 1995 have been amended under emergency procedures whereby the Secretary of State has been authorized for "ventilation shutdown" as a meth...

Video Game Addiction to Be Termed as a Medical Condition

The American Medical Association will decide later this month whether internet and video game addiction is a real disease. The doctors will vote on the issue at the AMA national meeting at Chicago. The tell tale signs of the new disease is teens holing up in their rooms, ignoring friends, family, even food and a shower, while grades plummet and belligerence soars. Video...
Termed at Medicine Products

Intermediate Hi-Lo® Tracheal Tube

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Precut Intermediate Hi-Lo® with Stylet

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Termed at Medicine Technology

PARI and Kamada Announce Positive Intermediate Phase I Results for Inhaled Alpha-1 Antitrypsin

MONTEREY, Calif., May 31, 2007 /PRNewswire-FirstCall/ -- Thefirst of two stages of the Phase I clinical trial show positiveresults for Kamada's Alpha-1 Antitrypsin (AAT) liquid drugcandidate for inhalation delivered with PARI's eFlow electronicnebulizer for the treatment of patients suffering from AATdeficiency. Dosage levels studied resulted in good safety profilesand patient tolerabili...

Oncophage Cancer Vaccine Significantly Prolongs Recurrence-Free Survival by 45 Percent in Patients With Intermediate-Risk Kidney Cancer

ANAHEIM, Calif.--(BUSINESS WIRE)--May 21, 2007 - Antigenics Inc.(NASDAQ: AGEN) today announced additional follow-up data on thecompany's Phase 3 investigational therapeutic cancer vaccineOncophage(R) (vitespen). The end-of-study results, which reflect anadditional 17 months' data collection, showed that in a substantialsubset of patients (n = 362) at intermediate risk for diseaserecurrence,...
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(Date:12/2/2008)...PRNewswire/ -- Breast-Specific Gamma Imaging (BSGI...g technique for the diagnosis of,invasive lobular...ancer. BSGI,is a molecular breast imaging techniq...sity and discover very early stage cancers. When c...esonance imaging (MRI), BSGI has the,greatest sen...
(Date:12/2/2008)...PRNewswire-USNewswire/ -- Today a group of health...cted officials and other community leaders from mo...roit/Wayne County to solidify participants, unders...conomic successes and challenges play a role in de...opening session of a three-day discussion to consi...
(Date:12/2/2008)... were as effective, despite editorials urging oppo...ws) -- Brand-name drugs used to treat cardiovascul...ew of available evidence shows. , Yet a number ...ialists, have urged against substituting the less .... , "We found no evidence that brand-name drugs...
(Date:12/2/2008)...ists from the USC Viterbi School of Engineering ha...s for operating rooms at three California safety n... surgery per year." Because of the success of the ...e more hospitals. , A team from the Viterbi Scho...Engineering began work in January, 2008 at Childre...
Breaking Medicine News(10 mins):Health News:Molecular Breast Imaging Has Greater Sensitivity Over Mammography, Ultrasound and MRI for Invasive Lobular Carcinoma 2Health News:Think Tank Investigates the Environmental Conditions Surrounding Health Inequities 2Health News:Think Tank Investigates the Environmental Conditions Surrounding Health Inequities 3Health News:Generic Heart Drugs as Good as Brand-Name Counterparts 2Health News:Generic Heart Drugs as Good as Brand-Name Counterparts 3Health News:Operations engineering for more efficient operating rooms 2Health News:Operations engineering for more efficient operating rooms 3
(Date:12/1/2008)... Capital Projecta collaboration of Stanford Univer...ture Conservancy and the World Wildlife Fundhas be...e Gordon and Betty Moore Foundation to develop a s...nomic benefits provided by temperate marine ecosys...on of Ecosystem Services and Tradeoffs), the propo...
(Date:12/1/2008)..., Fla. The University of Florida, keeper of the w...g a national records collection for another toothy...y a long rostrum or "saw" that makes it a popular ...become a historical and cultural icon that is rapi...ologist and curator of both the International Shar...
(Date:12/1/2008)...: The Missouri Botanical Garden Press (MBG Press)... the species of vascular plants for the Southern C...a. Catlogo de las Plantas Vasculares del Cono Sur ...a taxonomic checklist of the plants of Argentina, ... database is essentially a dictionary to the names...
(Date:12/1/2008)...l. (December 1, 2008) The basic molecules that ma...lity or "handedness," similar to the way people ar...ound influence on the chemistry and molecular inte...rality from the elementary building blocks of matt...life. Scientists at the U.S. Department of Energy...
Breaking Biology News(10 mins):Natural Capital Project to develop conservation software 2Endangered sawfish focus of national collection and recovery efforts 2Missouri Botanical Garden publishes first catalogue of plants of the Southern Cone 2Argonne scientists discover possible mechanism for creating 'handedness' in biological molecules 2TVM Capital Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 7260 1TVM Capital Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 7260 2TVM Capital Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 7260 3TVM Capital Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 7260 4TVM Capital Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 7260 5Clear 28R 29 Secures 2444 4 Million in Venture Funding 4555 1Clear 28R 29 Secures 2444 4 Million in Venture Funding 4555 2Clear 28R 29 Secures 2444 4 Million in Venture Funding 4555 3PTC124 shows activity in cystic fibrosis 3B Phase 2 proof of concept data published in Lancet 4554 1PTC124 shows activity in cystic fibrosis 3B Phase 2 proof of concept data published in Lancet 4554 2PTC124 shows activity in cystic fibrosis 3B Phase 2 proof of concept data published in Lancet 4554 3Slogan Contest Educates Young Baseball Players About the Dangers of Tobacco Use 25636 1Slogan Contest Educates Young Baseball Players About the Dangers of Tobacco Use 25636 2
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