Novel Enzyme Shows Potential As An Anti-HIV Target
At just 9.8 kilobases, the HIV genome pales in comparison to the 3.2 gigabases of its human and nonhuman primate targets. The compact retrovirus encodes just 14 proteins, which play different roles in promoting viral infection and virulence. As a retrovirus, HIV uses the host’s cellular machinery—including RNA polymerases, which carry out transcription—to copy its RNA genome into DNA and infiltra...Dinosaur DNA? New Patent Covers Degraded DNA recovery
The US Patent Office issued Patent # 6,872,552, "A Method of Reconstituting Nucleic Acid Molecules" today to Burt D. Ensley, Ph.D, Chairman of MatrixDesign, and CEO of DermaPlus, Inc. The patent covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scientists to reassemble everything from prehistoric, extinct animals to unsolved crime scenes. "...Scientists decipher genome of fungus that can cause life-threatening infections
In a project that already has benefited animportant field of biomedical research, scientists have deciphered thegenomes of two closely related strains of Cryptococcus neoformans, afungus whose importance as a human pathogen has risen in parallel withthe HIV/AIDS worldwide epidemic and the increased use ofimmunosuppressive therapies.The study, posted online January 13 in Science Express, rev...Essential mangrove forest threatened by cryptic ecological degradation
The recent killer tsunami has highlighted once more the importance of coastline protection. In natural conditions, this function is taken up by mangroves, forests thriving at the edge of land and sea that are ecologically and socio-economically important for local people in tropical countries on all continents. Using biology, geography, hydrology, socio-economic interviews, and 18th-century histo...New research questions basic tenet of neuron function
New findings by researchers at UT Southwestern Medical Center challenge one of the established views of how nerve cells communicate with one another. Every time we move, feel emotions, think or remember, the nerve cells, or neurons, in our body transmit messages to one another via chemical signals called neurotransmitters. Within neurons are tiny organelles called synaptic vesicles that s...Transformance™ competent cell preparation service from Lucigen
Description:Do you need to make your strain of cells competent or increase their transformation efficiency? Take advantage of Lucigen’s unrivalled expertise in producing competent cells. Lucigen’s Transformance Custom Competent Cell Service offers: Quality control p...pET GST Fusion System 42 plus Competent Cells from Novagen
Description:Schistosomal glutathione-S-transferase (GST) is commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been reported to enhance the production and in some cases the solubility of its fusion partners. When expressed in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with buf...pET GST Fusion System 41 plus Competent Cells from Novagen
Description:Schistosomal glutathione-S-transferase (GST) is commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been reported to enhance the production and in some cases the solubility of its fusion partners. When expressed in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with...Breeding and Maintenance (Nonhuman Primates) from Alpha Genesis, Inc.
Description:AGI provides both long and short-term enriched housing for nonhuman primates and other laboratory animals in both quarantine and non-quarantine settings on a per diem basis. Breeding services are also available utilizing our state-of-the-art social housing and nursery facilities. In addition, AGI is equipped with on site CDC quarantine facilities. Primate housing and CDC quarantine systems...a-Hyb Hybridization Station from Miltenyi Biotec
Description:fully automated system for the processing of microarrays on microscope slides...Versatile Transfection Reagent Offers Low Toxicity and Consistent Performance
Stratagene transfection reagent offersimproved, consistent transfections for both adherent cells and cells growing insuspension. In this article, we summarize the results of several experimentsthat characterize the eff...New Competent Cells for Highest Transformation Efficiencies
Stratagene Cloning Systems, Inc. Stratagenes new, high-efficiency competent E. coli cell linesignificantly improves the transformation efficiency of ligated DNA. EpicurianColi ultracompetent cells* yi...Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures
Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient delivery of DNA to primary neuronal cell cultures is of critical importance...Effectene Transfection Reagent
For transfection of a wide variety of cells, particularly effective for primary cells <l...Purification of the Components of Human Macular Carotenoid-Binding Complex, Rev A
The macular region of the human retina is responsible for almost all color vision and most of the high resolution visual acuity. This part of the retina, known as the macula lutea, or yellow spot, accumulates approximately 200 ng of two closely-related compounds, lutein and zeaxanthin....PRIMARY PULMONARY HYPERTENSION GENE DISCOVERED
The discovery of the gene associated with the inherited form of primary pulmonary hypertension (PPH) by Drs. Jane H. Morse of Columbia University and James A. Knowles of the Columbia Genome Center is indeed a major breakthrough. Their study, funded in part by the National Heart, Lung, and Blood Institute at the National Institutes of Health and published in the September issue of th...Painkillers Do Not Shorten Dying Patients' Lives
According to some British researhers increasing doses of painkillers to ease the agony of terminally ill patients does not shorten their lives.Some health professionals have criticized the practice, comparing it to euthanasia, but doctors at St Christopher's Hospice in London claim patients receiving higher doses of drugs such as morphine live just as long as those who do not. In re...Potential New Cancer Gene Identified
A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer. Characterized by rapidly growing abdominal tumors, Burkitt's lymp...Thyroid hormone treatment hastens recovery after cardiac surgery
Thyroid hormone treatment after surgery requiring heart bypass speeds recovery in children undergoing correction of congenital heart defects, according to a clinical trial published in The Lancet. The effects were greatest in the patients who underwent long and difficult surgeries. Following trauma or surgery or during a critical illness, thyroid hormone concentrations plummet. Ma...Startling Expose – Physicians Often Have No Regular Source Of Health Car
Startling! But true! In a censure of the doctors around the world, a study conducted by researchers at the prestigious Yale and Johns Hopkins Universities has revealed that more than a third of physicians have no regular source of healthcare Dr. Cary P Gross of Yale University is New Haven, Connecticut says, ‘ these physicians without a regular source of health care are less likely than...Tenzel Double-Ended Periosteal Elevator
Description:4 mm x 6 mm dissector end with shaft marked at 10 mm, 20 mm, 30 mm from tip. 6 mm wide curved elevator. Round knurled handle....BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
LINCOLNSHIRE, Ill.--(BUSINESS WIRE)--Jul 11, 2007 - BioSantePharmaceuticals, Inc. (Amex: BPA) today announced new positiveresults demonstrating that its calcium phosphate (CaP)nanoparticle-based vaccine adjuvant, BioVant(TM), may serve as aneffective vaccine adjuvant for the development of a dose sparingvaccine against H5N1 avian flu, widely known as bird flu. The new results are based on...New Information on the Potential of Plasmin Shared at ISTH Congress
RESEARCH TRIANGLE PARK, N.C. & GENEVA--(BUSINESS WIRE)--Jul 11,2007 - New information representing the continuing research anddevelopment program for Plasmin (Human), TAL-05-00018, waspresented by Talecris Biotherapeutics, Inc.(http://www.talecris.com) this week at the XXIst InternationalSociety for Thrombosis and Haemostasis (ISTH) Congress in Geneva,Switzerland. The information includ...CV Therapeutics Identifies Potential Anti-Diabetic Mechanism of Action for Ranexa
-- New Preclinical Information May Correlate with Clinical HbA1cReductions Observed in Phase 3 CARISA and MERLIN TIMI-36 ClinicalTrials -- PALO ALTO, Calif., July 9, 2007 /PRNewswire-FirstCall/ -- CVTherapeutics, Inc. announced today that researchers have completedpreliminary preclinical studies showing that ranolazine increasedglucose stimulated insulin secretion in pancreatic beta cells...