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Telomerase at Biology News

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres ?small pieces of DNA on the ends of chromosomes that act as protective caps -- allowing DNA ends to be copied completely when cells are replicated. This is the first major piece of telomerase for which the structure is known. Telomerase plays a key rol...

A little telomerase isn't enough

With seed money from Johns Hopkins Institute of Cell Engineering, a Johns Hopkins geneticist and her team have discovered a critical link between the health of stem cells and the length of the chromosome ends within them. Chromosome ends, or telomeres, are repetitive stretches of DNA that protect chromosomes in much the same way as plastic tips on shoelaces prevent the fabric from fraying....
Telomerase at Biology Products

Telomerase Gel-based assay Assay Kit, TRAPeze from CHEMICON

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Company:CHEMICON

Telomerase Fluorometric Assay Kit, TRAPeze from CHEMICON

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Company:CHEMICON

Telomerase ELISA Assay Kit, TRAPEZE from CHEMICON

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Company:CHEMICON

TRAPEZE® RT Telomerase Detection Kit from CHEMICON

Description:The TRAPeze RT Telomerase Detection Kit is a highly sensitive in vitro assay for the fluorometric detection and real time quantification of telomerase activity. It incorporates refinements to the original TRAPeze assay and adds the ability to quantitate telomerase activity using fluorescence energy transfer (ET) primers....
Company:CHEMICON
Telomerase at Biology Technology
Telomerase at Biology Dictionary

Telomerase

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Telomerase at Medicine News

Urine testing for telomerase enzyme for bladder cancer diagnosis

Dr Maria Aurora Sanchini and her colleagues from Italy have found a new urine test which detects bladder cancer// in people with high-risk of cancer occurrence. The test which is proved to be 90% accurate is used to measure the level of the enzyme telomerase in urine of patients. The results of the study have been published in the Journal of the American Medical Association. The study would be ve...

Telomerase Vital In Maintaining Ability of Stem Cell to Multiply

Carol Greider, Ph.D., director and professor of molecular biology and genetics in the Johns Hopkins Institute of Basic Biomedical Sciences and colleagues have found that the length of telomeres is important// in ensuring that stem cells are able to divide indefinitely. Telomeres are the ends of the chromosomes that protect genetic information while the chromosome is undergoing division....

Telomerase Expression Linked To Body Mass

Telomerase is an enzyme that is known to have healing properties. It was earlier considered that the lifespan of an organism and the amount of telomerase expressed were// related but it is now been linked to body mass.Telomerase is also known to increase the rate of cancer. Vera Gorbunova, assistant professor of biology at the University of Rochester, conducted a first-of-its-kind s...
Telomerase at Medicine Products
Telomerase at Medicine Technology

Geron Corp. Licensee TA Sciences Announces Landmark 7/07/07 Teleconference to Answer Questions About TA-65, Their Telomerase Activator With Proven Age Management Benefits

NEW YORK, June 15, 2007 /PRNewswire/ -- Telomerase ActivationSciences, Inc. (T.A. Sciences) recently announced the results ofthe Pivotal 2005 Anti-Aging Trial of TA-65, the first human trialever to show demonstrated, measurable and positive anti-agingbenefits from a Telomerase Activator. Statistically significantresults were found in those taking TA-65 across several keyconditions of agi...

Geron's Telomerase Inhibitor Cancer Drug Demonstrates Good Pharmacokinetics and Tolerability in Phase I/II Trial

MENLO PARK, Calif.--(BUSINESS WIRE)--Jun 12, 2007 - GeronCorporation's (Nasdaq:GERN) telomerase inhibitor cancer drug,GRN163L, has demonstrated good pharmacokinetics and tolerability inits ongoing Phase I/II trial involving patients with chroniclymphocytic leukemia (CLL), according to data presented today byAlan Colowick, M.D., M.P.H., the company's president, oncology, atthe Pan Pacific Ly...

Telomerase Presentations at the AACR 2007 Annual Meeting

MENLO PARK, Calif.--(BUSINESS WIRE)--Apr 25, 2007 - GeronCorporation (Nasdaq:GERN) today referenced multiple presentationson the role of telomerase and telomeres in cancer at this year'sAmerican Association for Cancer Research (AACR) Annual Meeting inLos Angeles. There were approximately 80 presentations on telomereand telomerase biology reflecting the growing body of evidencesupporting the...
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