Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...New, automated tool successfully classifies and relates proteins in unprecedented way
For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a cell.The approach, developed by Carnegie Mellon University, outperformsexisting visual methods to localize proteins inside cells...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
Currently available lines of human embryonicstem cells have been contaminated with a non-human molecule thatcompromises their potential therapeutic use in human subjects,according to research by investigators at the University of California,San Diego (UCSD) School of Medicine and the Salk Institute in La Jolla,California.In a study published online January 23, 2005 in the journal NatureMed...Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine
When the most common adult leukemia in the United States was last reviewed by the New England Journal of Medicine (NEJM) in 1995, it was seen through the eyes of theories that dated back to the 1960s. As such, the journal recently invited three of the world's foremost experts on chronic lymphocytic leukemia (CLL) to write an authoritative update covering the transformation in the scientific commu...Mouse Anti-Amodiaquine Monoclonal Antibody, Unconjugated, Clone 6D10 from AntibodyShop A/S
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Quantitating cell number is more accurate using the Quantos cellproliferation assay kit Genetic Applications LLC cell proliferation assay kitprovides a simple, reproducible method to assess the number of cells present invarious tissue culture dish formats. In this st...Use of Cellular Phones associated with Increased risk of Brain Tumors
A recent article published by a team in Sweden suggests that there is an increased risk of brain cancer in the areas of highest exposure in patients using digital telephones (Case Control Study on Radiology work, Medical X-Ray Investigations, and Cellular Telephones as Risk Factors for Brain Tumors, Hardell, et al, May 4, 2000, www.medscape.com). Their analysis focused on the effect of d...Asthma may actually be prevented by Dust and Dirt
National Jewish Medical and Research Center researchers in USA say that a little dust and dirt in the home may help prevent asthma later in life. Environmental endotoxin may have an allergy-protective effect in some infants whose homes have high levels of the bacteria by-product. "Endotoxin seems to drive the immune system to produce cytokines that inhibit certain processes in the body th...A prescription cream for unwanted facial hair
VaniqaT is a prescription drug which was approved by the FDA in the United States on July 31, 2000 for treating excessive facial hair in women, which is often part of hirsutism. It may be a welcome alternative for women for whom this problem is considered serious enough to warrant tweezing, waxing, or shaving at least once a week for hair removal. Vaniqa is actually not a b...Feeding channel created by malaria parasite - a new target for malaria treatments
Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce. The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Mala...Long-Term Survival can be Predicted by a Simple Lung Test
Researchers have found a simple pulmonary test can predict overall long-term survival rates in both men and women. Their findings are presented in the September issue of Chest. Researchers studied survival rates based on a lung function test, called forced expiratory volume in one second (FEV1).They performed the lung function test on a group of more than 550 men and more than 640 wom...Cystotome Curved, Twisted Tip, 27 g
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Contributing Editor Harvard Medical School The yeast ) and pulmonary hypersensitivity (<...Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
Contributing Editor With over 200,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most serious health problems. Recently, efforts to develop early detection methods and more effective therapy have made important progress. This is particularly...Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal
Medical conventions are challenged every day. Already in the new year, the effectiveness of cold medicine and the gold standard in breast cancer treatment have been challenged. Standards in cholesterol testing are the latest casualty of medical innovation. For years, cholesterol has been measured by a simple panel o...Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
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