Targeting

HIV 'Atlas' Shows Virus Targeting Minorities

80% of U.S. cases occur in just 20% of counties, report finds MONDAY, June 22 (HealthDay News) -- Your chances of getting infected with HIV may largely depend on where in America you live, a new report finds. The HIV/AIDS Atlas found that 80 percent of U.S. cases are clustered in ...

Neuromed Announces that Merck & Co., Inc. Terminates Research Collaboration and License Agreement for Compounds Targeting N-Type Calcium Channels

CONSHOHOCKEN, PA and VANCOUVER, BC, June 11 /PRNewswire/ - Neuromed Pharmaceuticals Ltd. announced today that it has received notification that Merck & Co., Inc. will terminate the research collaboration and license agreement for novel compounds targeting N-type calcium channels for the treatm...

Edifecs(TM) and Axway Announce a Partnership Targeting Innovative HIPAA 5010 Migration Solutions.

Edifecs unveiled a new partnership with Axway to provide innovative solutions specially designed by healthcare migration professionals and technologists to address the challenges of implementing HIPAA 5010 transactions in a timely and cost-effective manner. BELLEVUE, Wash., May 20 /PRNewswire...

Stem Cell Study Offers Hope for Targeting Tumors

In mice, genetically engineered cells killed cancer but spared healthy cells TUESDAY, May 19 (HealthDay News) -- Genetically engineered adult stem cells, armed with a cancer-killing protein, have proven successful at targeting several types of tumors while sparing healthy cells, new r...

Migraine prevention by targeting glutamate receptors?

When migraine strikes, because of severe pain, often accompanied by nausea and sensitivity to light and sound, sufferers are effectively disabled for up to 72 hours. Since they are forced to stop what they are doing until the pain and other symptoms subside, migraine causes a significant loss in p...

Deadly in Pink: New Report Warns Big Tobacco Has Stepped Up Targeting of Women and Girls

Congress Urged to Grant FDA Authority over Tobacco Products WASHINGTON, Feb. 18 /PRNewswire-USNewswire/ -- The tobacco industry has unleashed its most aggressive marketing campaigns aimed at women and girls in over a decade, according to a report issued today by a coalition of public healt...

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Targeting in Medical Technology

Dendreon Initiates Phase 1 Clinical Trial of Small Molecule Targeting TRPM8 in Cancer

SEATTLE, April 21 /PRNewswire-FirstCall/ -- Dendreon Corporation (Nasdaq: DNDN ) today announced that the Company has enrolled the first patient in a Phase 1 clinical trial of D3263 in patients with advanced cancer. D3263 is Dendreon's lead small molecule drug candidate designed to target TRPM8...

Raptor Pharmaceuticals Provides Update on Targeting Platforms

Enters Collaboration on Receptor Associated Protein (RAP) Supports NeuroTrans(TM) Platform with Japanese Patent NOVATO, Calif., Nov. 6 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced updates on its preclinical p...

Medarex Receives Milestone Payment for Investigational Antibody Targeting Integrin Receptors

PRINCETON, N.J., Nov. 5 /PRNewswire-FirstCall/ -- Medarex, Inc. (Nasdaq: MEDX ) today announced that it has received a milestone payment of an undisclosed amount from its licensing partner, Centocor R&D Inc., for the completion of a Phase 2 trial of CNTO 95, a fully human antibody targeting t...

MedImmune Advances Asthma Program with Start of a Phase 2 Trial in Europe and Australia and First U.S.-Based Clinical Trial for Antibody Targeting IL-13

GAITHERSBURG, Md., April 15 /PRNewswire/ -- MedImmune today announced that it has advanced its efforts to develop CAT-354, a potential treatment for patients with asthma, with the start of two new trials with a monoclonal antibody (MAb) targeting interleukin-13 (IL-13). One of the studies is a...

Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies

-Combination of a Bavituximab Equivalent and an Agent that Re-Activates the Tumor Suppressor P53 Inhibited Tumor Growth Synergistically in Preclinical Breast Cancer Models- SAN DIEGO and TUSTIN, Calif., April 14 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. (...

Dutch Top Institute Allocates 150 Million Euro to R&D Projects Targeting Early Diagnosis and Treatment of Disease

EINDHOVEN, the Netherlands, April 1 /PRNewswire/ -- The Center for Translational Molecular Medicine (CTMM) - a Dutch public-private partnership committed to the research and development of new techniques for the diagnosis and treatment of major diseases - announced today that nine projects wil...

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Targeting in Medical Products

Autolet Impression

Description:... Zone Technology and Force Adjustment that allows ultimate control and comfort when lancing. Comfort Zone Technology increases comfort when lancing by targeting the sensation and perception of pain. This approach masks the pain of lancing to maximize comfort when sampling....
Company:Owen Mumford, Inc.

Photosilk

Description:... operating time. Photosilk is an effective and reliable pulsed light system for faster and extensive treatments suitable for any phototype, especially targeting fairer skins. These characteristics make it a real help for the operator who will be now able to satisfy all customers with successful results in a fe...
Company:DEKA Research & Development Corp.

Parvovirus (Erythrovirus) B-19 ASR

Description:... The Parvo B19 ASR contains primers and a FAM-labeled probe targeting the VP1 gene of Parvovirus B19. In addition, the Parvo B19 ASR contains primers and a Texas Red-labeled probe for an internal control sequence. This A...
Company:Cepheid

BioPlex® 2200

Description:...tomated bead-based multiplexing immunoassay platform that can deliver up to 2200 results per hour. The system will initially include a panel of assays targeting autoimmune diagnostics. Future assays in development are in the areas of serology, infectious disease, cardiac and toxicology....
Company:Bio-Rad Laboratories

HSV Typing ASR

Description:... The HSV Typing ASR contains primers and a FAM-labeled probe targeting the glycoprotein D gene of HSV Type 1 as well as primers and an Alexa 532-labeled probe designed to detect the glycoprotein G gene of HSV Type 2. This...
Company:Cepheid

Code Reader 2 Scanner

Description:... Supports both PC and Microsoft Windows CE platforms Reads most of the common matrix and linear bar codes Highly accurate, customizable laser targeting system Features omni-directional reading capabilities Features 1 year full replacement warranty ...
Company:Brady Corporation

Targeting in Medical Dictionary

Serotonin

...erotonin (pronounced /ˌsɛrəˈtoʊnən/) is a monoamine neurotransmitter. ... 2.3 Endothelial cell function and Serotonin . 3 Biosynthesis. 4 Drugs targeting the 5 ... serotonin n. An organic compound, C 10 H 12 N 2 O, formed from tryptophan and found in animal and human tissue, especially the bra...

Porphyrins

... body including hemoglobin, ... Porphyrins can be found in urine. ... New two-photon–activated porphyrin designs allow specific, noninvasive targeting of subcutaneous tumors several centimeters below the skin surface. The names of the porphyrins of interest consist of a word and a number, e...

Olfactory

...w to investigate the olfactory system and then find out how to ... is the story of olfactory sensory cells. ... Sema-1a also regulates PN axon targeting in higher olfactory centers. ... Representation of the Glomerular Olfactory Map in the Drosophila Brain ... Excitatory Interactions between O...

Immune response

...volves the activation of macrophages, which engulf ... New research could lead to revolutionary new approaches for treating allergies based on targeting T cells, white blood cells that regulate the immune response . The ... ... level viral infection and on the body’s own immune ...

Bullous pemphigoid

...bullae, at the space between the epidermis and dermis. The bullae are formed by an immune reaction, initiated by the formation of autoantibodies targeting the type XVII collagen component of... Pemphigoid is a group of uncommon and rare autoimmune blistering skin diseases. As its name indicates...

Alpha fetoprotein

...'s Health)( alpha fetoprotein ): An article from: ... Alpha - fetoprotein Testing ... How long do wait for the Alpha Fetoprotein test? ... targeting alpha - fetoprotein represses the proliferation of hepatoma cells via ... Serum alpha - fetoprotein (AFP) levels in breastfed infants with pro...

Targeting in Biological News

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

Washington, DC Cancer researchers at Georgetown University's Lombardi Comprehensive Cancer Center have successfully tested a small, engineered antibody they say shuts down growth of human glioblastoma tumors in cell and animal studies. Glioblastoma is the deadliest of brain cancers; there is no e...

UCLA researchers discover new molecular pathway for targeting cancer, disease

A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach. In the study, which is currently ava...

Motor nerve targeting to limb muscles is controlled by ephrin proteins

Montral, December 24, 2008 A study from a team of researchers including Dr. Artur Kania, Director of the Neural Circuit Development Research Unit at the IRCM, and Dr. Dayana Krawchuk, postdoctoral fellow, shows how a family of proteins present in the developing limb control nerve targeting from t...

AACR annual meeting showcases developments in understanding and targeting cancers

SAN DIEGO -- Cutting-edge breakthroughs in molecular targeting, translational cancer research and cancer prevention will take center stage when more than 17,000 scientists from around the world gather at the San Diego Convention Center April 12-16 for the 2008 Annual Meeting of the American Associ...

Titanium Group Announces Launch of New Identification Solution Targeting High Growth Retail Sector

NEW PRODUCT APPLIES TITANIUM'S BIOMETRIC TECHNOLOGY AND RFID FOR STOCK INVENTORY AND STORE FRONT SOLUTION SAN JOSE, Calif., Dec. 18 /PRNewswire-FirstCall/ -- Titanium Group, Ltd. (OTC Bulletin Board: TTNUF), a leading biometric and security solutions provider announced today...

Yale chemist receives NIH Young Investigator Award for antibody targeting

New Haven, Conn. David Spiegel , assistant professor of organic chemistry at Yale, has received a $1.5 million National Institutes of Health (NIH) Directors New Innovator Award that will support his work designing a rational approach for using antibodies to target a wide variety of cells and d...

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Targeting in Biological Technology

Aegera Initiates Phase 2 Clinical Trial Of AEG33773 - A Small Molecule Targeting Neuropathic Pain

MONTREAL, May 6 /PRNewswire/ - Aegera Therapeutics is pleased to announce the initiation of a Phase 2a, proof-of-concept, clinical trial for AEG33773, a novel, orally bio-available small molecule therapeutic addressing the under-served market of painful diabetic neuropathy. The Phase 2a study, e...

Further 100 Million Euros Allocated to Netherlands-Based R&D Targeting the Early Diagnosis and Treatment of Disease

EINDHOVEN, The Netherlands, March 10 /PRNewswire/ -- The Center for Translational Molecular Medicine (CTMM) - the Dutch public-private partnership committed to the research and development of new techniques for the diagnosis and treatment of major diseases - today announced that eight new rese...

Immune Targeting Systems Completes Second Tranche of Series-A Funding Bringing Total Funds Raised to More Than GBP5m

LONDON, January 28 /PRNewswire/ -- Immune Targeting Systems (ITS) Limited, a company developing synthetic vaccines for mutating viruses, today announced it has received GBP2.4m of investment as the second tranche of its series-A funding round. ITS's investors HealthCap, the London Technology F...

Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009

SEATTLE, Jan. 14 /PRNewswire-FirstCall/ -- In meetings held in association with the JP Morgan Healthcare Conference in San Francisco, Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) reviewed 2009 targeted milestones and 2008 accomplishments. CTI is seeking to obtain two new drug approvals...

MedImmune Advances Asthma Program With Start of Phase 2 Clinical Trial for Antibody Targeting IL-5 Receptor

GAITHERSBURG, Md., Dec. 4 /PRNewswire/ -- MedImmune today announced that it has initiated a Phase 2 clinical trial in patients with chronic asthma to determine the safety of subcutaneous dosing of a humanized monoclonal antibody (MAb) that targets the interleukin-5 receptor (IL-5R). Preclinical da...

InNexus Biotechnology Announces New EGFR Antibody DXL1218 Targeting Colorectal Cancer and Announces $1.25 Million Private Placement

- Innovative Biotech Targets Another Large Well-Known Product and Continues Expansion of Antibody Therapeutics Pipeline - BRITISH COLUMBIA, Canada, Nov. 7 /PRNewswire-FirstCall/ -- InNexus Biotechnology Inc., (OTC Bulletin Board: IXSBF; TSX Venture: IXS; http://www.ixsbio.com ), a d...

Targeting in Biological Products

Rabbit Anti-Conjugated Quinaldic Acid Polyclonal Antibody, Unconjugated from Advanced Targeting Systems

Description: Anti-Conjugated Quinaldic Acid...
Company:Advanced Targeting Systems

pHyPer-dMito from Evrogen JSC

Description:...eukaryotic (mammalian) expression vector designed to express mitochondria-targeted HyPer. pHyPer-dMito carries HyPer fused to duplicated mitochondrial targeting sequence (MTS)....
Company:Evrogen JSC

* Quick & Easy Conditional Knock Out Kit - FRT from Gene Bridges GmbH

Description:...rature for E.coli ) and 40C (mouse body temperature). This kit can also be used to work on bacterial artificial chromosomes (BACs). The generation of targeting constructs is achieved utilizing the high Red/ET efficiency plus the convenient removal of the Red/ET Recombineering protein expression plasmid pRedET...
Company:Gene Bridges GmbH

* Quick & Easy Conditional Knock Out Kit - loxP from Gene Bridges GmbH

Description:...pression plasmid allows Cre recombination in E.coli . This kit can also be used to work on bacterial artificial chromosomes (BACs). The generation of targeting constructs is achieved utilizing the high Red/ET efficiency plus the convenient removal of the Red/ET Recombineering protein expression plasmid pRedET...
Company:Gene Bridges GmbH

FRT flanked, Pro and Euk. Neomycin Selection Cassette plus loxP site(FRT-PGK-gb2-neo-FRT-loxP) from Gene Bridges GmbH

Description:...of choice. The restriction sites can be introduced by adding the corresponding sequence in the PCR primer. The template can easily be used to generate targeting constructs mediated by Red/ET Recombination. The FRT-PGK-gb2-neo-FRT-loxP template is not linear but plasmid based (3485 bp in size). Due to its R6K ...
Company:Gene Bridges GmbH

loxP flanked, Pro and Euk. Neomycin Selection Cassette (loxP-PGK-gb2-neo-loxP) from Gene Bridges GmbH

Description:...of choice. The restriction sites can be introduced by adding the corresponding sequence in the PCR primer. The template can easily be used to generate targeting constructs mediated by a single Red/ET Recombination step. The loxP-PGK-gb2-neo-loxP template is not linear but plasmid based (3446bp in size). Due t...
Company:Gene Bridges GmbH

Targeting in Biological Definition

Malaria

...stern Reserve University in Ohio in 2002 (See Jacobs-Lorena et al, 2002) [4] . A major public health effort to eradicate malaria by selectively targeting mosquitos in areas where malaria was rampant was embarked upon in the 1950s and 1960s. ( The Mosquito Killer — PDF of the same article ) Since...

Peroxisome

...are imported from the cytosol . Each enzyme transferred to a peroxisome has a special sequence at one end of the protein, called a PTS or peroxisomal targeting signal , that allows the protein to be taken into that organelle, where they then function to rid the cell of toxic substances. Peroxisomes also deg...

Protein

...emistry Crystallography Denatured protein Intein Peptide Prion Proteinoid Protein structure prediction Protein targeting Proteome Proteomics Ribosome Structural genomics External links Proteins: Biogenesis to Degradation - The Virtual Librar...

Targeting in Biological Dictionary

Gene targeting

Gene targeting is a genetic technique that uses homologous recombination to change an endogenous gene . The method can be used to delete a gene , remove exons, add a gene , and introduce point mutations. Gene targeting can be permanent or conditional. Conditions can be a specific time duri...

Vesicle

...41 gene products] ... Definition and other additional information on Vesicle from Biology-Online.org dictionary. ... regulated, about vesicle targeting with clathrin coat proteins ... The synaptic vesicle cycle. Synapses can fire at very rapid rates. ... Synaptic vesicle components are initia...

Untranslated region

... of beta-globin transcripts linked to the c-myc 3' untranslated region . ... Distinct regions in the 3' untranslated region are responsible for targeting and ... An electronic protocol book with 500 protocols ... Untranslated region (UTR) Untranslated region (UTR) ... Untranscribed Region . ...

Transport vesicle

...ore specifically, transport vesicles are usually refered to those ... Transport vesicles - Glossary Entry - Genetics Home Reference ... The targeting of transport vesicles to the correct membrane destination involves ... the steps involved in delivering a newly formed transport vesicle to it...

Site-specific recombination

...ox recombination is a special type of site - specific recombination developed by Dr. Brian Sauer (DuPont) . Cre-Lox recombination involves the targeting of a specific sequence of DNA and splicing it with the help of an... Aspects of the topic site - specific - recombination are discussed in th...

Ribosomal DNA genes

...l form of transcriptional silencing in yeast ribosomal DNA . Genes Dev. ... Transcription of Multiple Yeast Ribosomal DNA Genes Requires targeting of UAF to ... Chromatin Assembly onto Active Ribosomal Genes in Yeast after UV ... ... counterpart of metaphase NORs, therefore being constit...