Targeted

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

Gene therapy methods that specifically target muscle may reverse the symptoms of a rare form of muscular dystrophy, according to new research in mice conducted by medical geneticists at Duke University Medical Center. Infants born with the inherited muscular disorder called Pompe disease usually die before they reach the age of two. The researchers also said their approach of targeting corrective...

Virginia Tech group adds tools to DNA-targeted anti-cancer drugs

Chemistry and biology researchers at Virginia Tech have enhanced the abilities of the molecules they are creating to deliver killing blows to cancer cells. The man-made molecular complexes enter cancer cells and, when signaled, deliver killing medicine or cause the cell to change. The new supermolecules have more units that will absorb light - providing more control over the range of light freque...

Affymetrix and ParAllele Launch Industry's Most Comprehensive Product Line for Targeted Genotyping

Twenty-eight years after intense selective logging stopped in the region now known as Uganda's Kibale National Park, the red-tailed guenon (Cercophithecus ascanius) is a primate still in decline. The logging practice, scientists report in a new study, changed the ecological balance for these monkeys, leading to behavioral changes and opening the door for multiple parasitic infections. The...

Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy

Safeguarding 595 sites around the world would help stave off an imminent global extinction crisis, according to new research published today in the Proceedings of the National Academy of Sciences ( Conducted by scientists working with the 52 member organizations of the Alliance for Zero Extinction (AZE –?<A HREF="http://www.zeroextinction.org...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates. Nucleic acid ligands (referred to as aptamers) are short DNA or RNA fragments that can bind to target an...

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Targeted at Biology Products

1-D PAGE Cleavable ICAT Reagent Applications Development Kit for Targeted Protein ID and Quantitation (monoplex Version) from Applied Biosystems

Description:The 1-D PAGE Cleavable ICAT Reagent Application Kit for Targeted Protein ID and Quantitation combines SDS PolyAcrylamide Gel Electrophoresis (PAGE), isotope-coded affinity tag chemistry, and cleavable-linker technology to facilitate the identification and quantification of differentially expressed proteins....
Company:Applied Biosystems

Targeted at Biology Technology

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Targeted at Medicine News

Treatment Resistant Tumors Can Be Targeted Better Using Botox

Botox, commonly used for cosmetic treatment may play an important role in enhancing the outcome of chemotherapy and radiotherapy, employed in cancer treatment. // Botox is a derivative of Botulinum toxin, a naturally occurring chemical known to cause intestinal poisoning. The toxin has numerous clinical applications such as relieving facial spasms, strabismus and treating muscle hyp...

Gel Offers A More Targeted Approach

Patients with diabetes, Crohn's disease, bowel cancer, constipation and other conditions may soon be able to take their medication orally instead of using injections.Scientists in India have developed a new oral gel that is able to deliver // drugs to manage diseases that often require an injection such as ulcerative colitis and some infections. The new gel can also prevent problems caus...

New Vaccine Targeted At Effective Treatment Against Tuberculosis

Globally, tuberculosis remains the number one killer in adults. TB is a lung disease, caused by a bacterium. Health experts say a new person is infected with TB somewhere in the world every second. // A vaccine against tuberculosis, termed BCG is currently available which, however, fails to protect against the most frequent form of disease, pulmonary tuberculosis in adults. Moreover, m...

Multi targeted approach required for suicide prevention in adolescents

New studies have revealed that depression may not be the only factor-probing adolescents to commit suicide.// Health care providers might therefore need to watch out for other mental health problems to prevent youth suicide. The World Health Organization re-examined the occurrence and distribution of mental disorders in 894 cases of completed suicides among young people worldwide. An an...

Doctors, Pharma Companies Targeted By CBI Raids

The Central Bureau of Investigation (CBI) carried out simultaneous raids on some government hospital doctors and pharmaceutical companies in Delhi and three other cities on Monday.// The raids were conducted in Chennai, Goa, and Thiruvananthapuram, besides the national capital, an official of the investigating agency said. The houses of Sudha Talan, head of Safdarjung Hospital...

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Targeted at Medicine Products

TargetScan Targeted Prostate Biopsy System

Description:TargetScan(R) is the latest innovation in prostate mapping, biopsy and cancer treatment guidance. Combining 3-D image acquisition with a stationary probe, this new technology helps physicians plan and execute targeted prostate biopsies -- potentially improving patients' cancer treatment outcomes with less-invasive procedures....
Company:Envisioneering Medical Technology

Targeted at Medicine Technology

Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy

Contributing Editor With over 200,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most serious health problems. Recently, efforts to develop early detection methods and more effective therapy have made important progress. This is particularly...

Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics

PHILADELPHIA, July 3, 2007 ? Researchers in Slovakia havebeen able to derive mesenchymal stem cells from human adipose, orfat, tissue and engineer them into “suicide genes” that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack smalltumor metastases that evade current detection techniques andtreatments, the researchers...

Antisense Pharma: Promising Phase IIb Results of Targeted Therapy with AP 12009 in Recurrent Anaplastic Astrocytoma

CHICAGO and REGENSBURG - June 21, 2007 - “In anaplasticastrocytoma, AP 12009 as a monotherapy is actually clearly superiorto temozolomide,” Prof. Albert Wong, M.D., StanfordUniversity, California, U.S.A. commented on the international PhaseIIb study with the TGF-beta 2-inhibitor AP 12009, under developmentby Antisense Pharma. Prof. Wong discussed the results of the studyin th...

Targeted Genetics Reports Inflammatory Arthritis Clinical Data at European Rheumatology Conference

BARCELONA, SPAIN and SEATTLE, WA -- (MARKET WIRE) -- June 14,2007 -- Targeted Genetics Corporation (NASDAQ: TGEN) today isreporting data from the dose escalation arm of the ongoing PhaseI/II clinical study of tgAAC94 in patients with inflammatoryarthritis. Philip J. Mease, M.D., clinical professor at theUniversity of Washington School of Medicine, chief of rheumatologyclinical research a...

Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood

Preclinical Studies Show 227Th-rituximab More Effective atKilling CD20-Positive Lymphoma Cells Than 90Y-tiuxetan-ibritumomab(Zevalin) OSLO, Norway, 14 June 2007 - Algeta ASA (OSE: ALGETA), theNorwegian cancer therapeutics company, announces that a researchpaper showing the potential of its TH-1 technology for targetedcancer therapy has been published by the leading medical journal,...

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