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TaqMan in Medical News

GeneGo and OmicSoft Announce Integration

...or the analysis of high dimensional quantification data (e.g. Microarray or taqman data), genotype data (e.g. SNP data, Copy Number data). The software is des...vides analysis modules for Exon/gene arrays, as well as an industry-leading taqman import and normalization module. With over 40 unique, fully interactive, an...

A new key to detecting deadly aortic aneurysms

...dentified using a complete workflow of instruments, reagents, and software from Applied Biosystems. These signature genes were further validated using taqman real-time PCR assays. The accuracy rate in various analyses is 78 percent to 85 percent. It has become increasingly evident that the immune syste...
TaqMan in Medical Technology

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...primary efficacy endpoint of the trial will be the proportion of patients who achieve an SVR, defined as undetectable levels of HCV (measured by Roche taqman assay) 24 weeks after completion of treatment. The trial will be conducted in North America, Europe and Australia. Patients will be enrolled into one ...

Diagenic Announces Launch of First Breast Cancer Gene-Expression Blood Test

...wing for widespread use to diagnose breast cancer at an early stage." The taqman Array manufactured for DiaGenic by Applied Biosystems consists of 96 TaqMan...nsky, president of Applied Biosystems' functional analysis division. "The taqman Arrays provide an ideal format for surveying gene expression markers based ...

Schering-Plough To Initiate Phase III Studies With HCV Protease Inhibitor Boceprevir in Previously Untreated Hepatitis C Patients and Those Who Failed Prior Treatment

...as defined above. (4) Intention-To-Treat (ITT) analysis includes any patient who has taken at least one dose of any study drug. (5) Roche Cobas taqman 1.0 assay; lower limit of detection is 15 IU/mL. ...

Interim Results from Boceprevir Phase II Study in Genotype 1 Treatment-Naive Hepatitis C Patients Presented At EASL

...r the end of treatment. 2 Intention-To-Treat (ITT) analysis includes any patient who has taken at least one dose of any study drug. 3 Roche Cobas taqman 1.0 assay; lower limit of detect ...

Final Results of Ideal Study Presented at Annual Meeting of the European Association for the Study of the Liver (EASL)

...ol, if a patient did not have a 24-week post- treatment assessment, the patient's 12-week post-treatment assessment was utilized. 3 Roche Cobas taqman 1.0 assay; lower limit of quantitation (LLQ) is 27 IU/mL. 4 Intention-To-Treat (ITT) analysis includes any patient who has taken at least one d...

Schering-Plough Reports Top-Line Results of the IDEAL Study

...ol, if a patient did not have a 24-week post- treatment assessment, the patient's 12-week post-treatment assessment was utilized. 3 Roche Cobas taqman 1.0 assay; lower limit of detection is 15 IU/mL. ...

Initial Results of Phase II Study with HCV Protease Inhibitor Boceprevir in Treatment-Naive Hepatitis C Patients Show a High Rate of Early Virologic Response

... respectively, having undetectable virus (HCV-RNA) at week 12 of boceprevir therapy compared to 34 percent of patients in the control arm (Roche Cobas taqman 1.0 assay; lower limit of detection is 15 IU/mL). Treatment discontinuations due to adverse events were 12, 9, and 8 percent for patients in the bocep...
TaqMan in Medical Products

COBAS TaqMan Analyzer

Description: Next-generation real-time polymerase chain reaction (PCR) testing for clinical laboratories. The COBAS TaqMan 48 Analyzer allows automated real-time amplification and detection of DNA or RNA for up to two simultaneous assays....
Company:Roche Diagnostics

SmartCycler 8000 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exact ne...
Company:Cepheid

SmartCycler® 8000 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exac...
Company:Cepheid

SmartCycler 9600 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exac...
Company:Cepheid

SmartCycler 6400 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exact ne...
Company:Cepheid

SmartCycler 3200 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exact ne...
Company:Cepheid

SmartCycler® 3200 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exac...
Company:Cepheid

SmartCycler 4800 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exact ne...
Company:Cepheid

SmartCycler® 6400 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exac...
Company:Cepheid

SmartCycler 1600 System

Description:...instrument's optics allow application to the rapidly evolving needs of a molecular biology lab using detection methods including Molecular Beacons and taqman probes, Amplifluor and Scorpion primers, and intercalating dyes such as SYBR Green. Expandable Users can configure a system to suit their exac...
Company:Cepheid
TaqMan in Biological Technology

Amplification Efficiency of TaqMan Gene Expression Assays

TaqMan Gene Expression Assays average 100% efficiency (+/- 10%). Abstract Applied Biosystems has designed and manufactured over 40,000 real-time PCR assays for measuring the expression of genes in humans, mice, and rats. TaqMan Gene Expression Assays each consist ...

Oragene is compatible with TaqMan SNP genotyping

J. Chartier and H.C. Birnboim DNA Genotek Inc., Ottawa, ON, Canada DNA collected with Oragene works well with TaqMan SNP Genotyping Assays. SNPs in the thymidylate synthetase and apolipoprotein E genes were reliably detected. ...

The iCycler iQ Detection System for TaqMan Assays, Rev B

Faye Boeckman, Keith Hamby, and Larissa Tan, Bio-Rad Laboratories, 2000 Alfred Nobel Drive, Hercules, CA 94547 USA Introduction Specific fluorescent oligonucleotide probes allow for real-time monitoring of the polymerase...

Pharmasset and Roche Obtain FDA Consent to Start a Phase 2b Study With R7128 in Treatment Naive HCV Patients

...endpoint of the trial will be the proportion of patients that achieve a sustained virologic response (SVR), defined as undetectable (measured by Roche taqman assay) HCV RNA 24 weeks after completion of treatment. Patients will be enrolled into one of 5 arms: 24 weeks of total treatment, w...

Roche Real-Time HIV Test is Faster and Less Labor-Intensive Than Competitor's

...Comparison of the Roche COBAS Amplicor Monitor, Roche COBAS Ampliprep/COBAS taqman and Abbott RealTime Test assays for quantification of hepatitis C virus and...hlighted some key performance differences between the COBAS Ampliprep/COBAS taqman and Abbott RealTime assays using m2000sp and m2000rt. Workflow is so criti...

The New Affymetrix GeneChip Scanner 3000

...s showed that a subset of these transcripts was frequently called Present or Marginal in the 0.00 pM target sample across the scanner types and sites. taqman RT-PCR analysis was performed to examine the possibility of endogenous levels of all 53 transcripts. This analysis showed marginal evidence of express...

Multiplexed Quantitative Peptide Assays for Protein Biomarkers of Cardiovascular Disease in Human Plasma

...ssion studies or other genomic information. While these genomic markers can be validated at the RNA level using real time PCR assays such as taqman kits, and at the protein level using Western blots, validation at the protein level requires specific antibodies to each protein which is a very time ...

Genome Wide Profiling of Paired Cancerous and Normal Breast Tissues and Rapid Interpretation of Gene Expression Data

...t can be linked to the Celera Discovery System and taqman Gene Expression Assays for further in-depth gene e...s validated using quantitative realtime PCR (using taqman Gene Expression Assays). Met... tissues with p-values Validation with taqman Gene Expression Assays To confirm the ...

Laser Capture Microdissection of Cells Labeled with Enhanced Green Fluorescent Protein

...uipped with Fluor 300 epifluorescence optics optimized for EGFP ◊ taqman ABI Prism 7000 Sequence Detection System (Applied Biosystems, Foster City, ... 1 Expression of neural crest gene markers was determined using taqman quantitative realtime PCR. 2 + indicates detectable levels of g...

Laser Capture Microdissection (LCM) and Expression Profiling of Long-Range Projection Neurons

...these genes was shown by in situ hybridization and taqman quantitative RT-PCR. Herein we demonstrate how the...dak) VII. REVERSE TRANSCRIPTION AND taqman QUANTITATIVE PCR ◊ RETROscript Kit...obes and sequence detection primers ◊ taqman Master Mix (Applied Biosystems, Cat.#4304437) ...
TaqMan in Biological Products

QXL 520 C2 maleimide from AnaSpec

Description:...cking between three recently characterized G protein-coupled receptors. J Neurochem 77, 476-85; Nasarabadi S, et al. (1999). Simultaneous detection of taqman probes containing FAM and TAMRA reporter fluorophores. Biotechniques 27, 1116-8....
Company:AnaSpec

Beacon Designer from PREMIER Biosoft International

Description:...d server. Beacon Designer can be used to evaluate pre-designed assays and designing compatible oligos to extend the designs. It can design beacons and taqman for single tube multiplex experiments....
Company:PREMIER Biosoft International

D-LUX Detection Platform from Invitrogen

Description:...rm offers exceptional performance with specificity and sensitivity equal to taqman probes, high signal/background ratio, and an expanded array of software des...ctions for fast and easy primer design. All this for about half the cost of taqman probes. Design your own custom primers using Invitrogens D-LUX Designer Sof...
Company:Invitrogen
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