GATA: a graphic alignment tool for comparative sequence analysis
...ble to telomerase. The researchers found that both tankyrase 1 activity and telomere shortening decrease the effects of telomerase inhibitors. Importantly, tankyrase inhibition enhanced telomere shortening upon treat... cancer therapeutics. We expect that inhibition of tankyrase 1 will compensate for incomplete inhibition of tel...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...ble to telomerase. The researchers found that both tankyrase 1 activity and telomere shortening decrease the effects of telomerase inhibitors. Importantly, tankyrase inhibition enhanced telomere shortening upon treat... cancer therapeutics. We expect that inhibition of tankyrase 1 will compensate for incomplete inhibition of tel...Tankyrase antibody (ab2184) | Abcam
Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, also known as TNKS, is a human gene.Tankyrase 1 and Tankyrase 2 Are Essential but Redundant for Mouse ...
Tankyrase 1 contains 24 ankyrin (ANK) repeats near the N-terminus, that mediate ... The C-terminus of tankyrase contains a catalytic domain with poly(ADP-ribose) ...Tankyrase is a golgi-associated mitogen-activated protein kinase ...
The poly(ADP-ribose) polymerase tankyrase was originally described as a ... We further colocalized tankyrase with GLUT4 storage vesicles in the juxtanuclear ...Current Biology - Tankyrase promotes telomere elongation in human ...
Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics ... Conversely, either tankyrase 1 upregulation or telomere shortening, each of ...Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle ...
Tankyrase-1 localizes to mitotic spindle poles, to telomeres4 and to the Golgi ... We also demonstrate a requirement for tankyrase-1 in the assembly of bipolar ...Tankyrase: A new breed of telomere security guard -- Williams, 10.1083 ...
Tankyrase 1 deficiency can prompt sister telomere fusion (arrowheads). At mitosis, a protein called tankyrase 1 serves as protector by separating ...