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Tankyrase in Biological News

GATA: a graphic alignment tool for comparative sequence analysis

...ble to telomerase. The researchers found that both tankyrase 1 activity and telomere shortening decrease the effects of telomerase inhibitors. Importantly, tankyrase inhibition enhanced telomere shortening upon treat... cancer therapeutics. We expect that inhibition of tankyrase 1 will compensate for incomplete inhibition of tel...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...ble to telomerase. The researchers found that both tankyrase 1 activity and telomere shortening decrease the effects of telomerase inhibitors. Importantly, tankyrase inhibition enhanced telomere shortening upon treat... cancer therapeutics. We expect that inhibition of tankyrase 1 will compensate for incomplete inhibition of tel...
Tankyrase in Biological Products

Rabbit Anti-Human Tankyrase 2 (TNKL (TNKS2) Polyclonal Antibody, Unconjugated from Lifespan Biosciences

Description: Anti-TNKS2 Polyclonal AntibodyOther Sub-Family: not assigned-Other Applications: ELISA, Western Blot...
Company:Lifespan Biosciences
Tankyrase in other areas

Tankyrase antibody (ab2184) | Abcam

Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, also known as TNKS, is a human gene.

Tankyrase 1 and Tankyrase 2 Are Essential but Redundant for Mouse ...

Tankyrase 1 contains 24 ankyrin (ANK) repeats near the N-terminus, that mediate ... The C-terminus of tankyrase contains a catalytic domain with poly(ADP-ribose) ...

Tankyrase is a golgi-associated mitogen-activated protein kinase ...

The poly(ADP-ribose) polymerase tankyrase was originally described as a ... We further colocalized tankyrase with GLUT4 storage vesicles in the juxtanuclear ...

Current Biology - Tankyrase promotes telomere elongation in human ...

Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics ... Conversely, either tankyrase 1 upregulation or telomere shortening, each of ...

Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle ...

Tankyrase-1 localizes to mitotic spindle poles, to telomeres4 and to the Golgi ... We also demonstrate a requirement for tankyrase-1 in the assembly of bipolar ...

Tankyrase: A new breed of telomere security guard -- Williams, 10.1083 ...

Tankyrase 1 deficiency can prompt sister telomere fusion (arrowheads). At mitosis, a protein called tankyrase 1 serves as protector by separating ...
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