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Kosan Presents Data on Lead Hsp90 Inhibitor, Tanespimycin, Showing Promising Antitumor Activity in Multiple Myeloma at ASCO

Tanespimycin TIME Registration Program to Begin Third Quarter 2007 HAYWARD, Calif., June 04, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated presented data from a dose-escalatingPhase 1b clinical trial of its lead Hsp90 inhibitor, tanespimycin(KOS-953) in combination with bortezomib (Velcade(R)), showing ahigh degree of antitumor activity and tolerability in patients withmult...

Kosan Presents Preliminary Phase 2 Data Showing Antitumor Activity of Hsp90 Inhibitor Tanespimycin in Metastatic Melanoma at ASCO

HAYWARD, Calif., June 04, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated presented preliminary data from a Phase 2monotherapy trial showing that tanespimycin demonstrated antitumoractivity and tolerability in patients with metastatic melanoma,including one patient with a BRAF mutation (V600E) who had failedprior chemotherapy (within 6 weeks of initiation) and while ontanesp...

Kosan Presents Data on Cardiac Safety Profile of Hsp90 Inhibitor Tanespimycin (KOS-953) at AACR

Tanespimycin Shown to Have No Effect on QTc Interval HAYWARD, Calif., April 16, 2007 /PRNewswire/ -- KosanBiosciences Incorporated today presented safety data frompreclinical and clinical studies of its lead Hsp90 inhibitor,tanespimycin (KOS-953). Serial electrocardiogram (ECG) monitoringof patients was conducted in four Phase 1 trials of tanespimycin.Cardiac monitoring analyses were cond...
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Breaking Medicine News(10 mins):Health News:Plan Your Breasts in 3-D 2Health News:Global Sourcing Strategies for the Pharmaceutical Industry 10th - 11th November, Marriott Princeton, New Jersey USA 2Health News:LegalView Informs Patients of Possible Cimzia Cancer Link, Drug Commonly Used to Treat Arthritis 2Health News:LegalView Informs Patients of Possible Cimzia Cancer Link, Drug Commonly Used to Treat Arthritis 3Health News:Seamobile Provides Foxnews To Mercy Ships 2Health News:Seamobile Provides Foxnews To Mercy Ships 3
(Date:10/6/2008)...rk, NY, October 6, 2008 -- A research study funded...a may provide some protection from developing type...p towards understanding how and why type 1 diabete...res. , The study, reported this week in Nature...hypothesis," that exposure to an appropriate amoun...
(Date:10/6/2008)...arch team at Cold Spring Harbor Laboratory (CSHL) ...cellular processes are disrupted in cancer. , L...vered that a "splicing factor" called SF2/ASF--a p... proteins are assembled--can induce tumors in cell... that, in ways not yet fully understood, this same...
(Date:10/6/2008)...UT HILL, MA (October 6, 2008) A gene contained in... of researchers uncover new findings about the pro...quences in genes in order to initiate gene express... Nature . , Previously thought to be inert carr...ed non-coding RNAs turn out to reveal a novel mech...
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