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TOPORS in Biological News

Protein can help cells or cause cancer, Purdue researcher finds

...ding a phosphate group to a protein called Topors. topors binds itself to p53 molecules during the ubiquitin...53 could be thought of as a protective force. When topors kills off that force, Plk1 becomes stronger, allow...sed in cancers, it is a cancer therapy target." topors can also carry out a function called sumoylation, ...
TOPORS in other areas

TOPORS - Wikipedia, the free encyclopedia

"Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich" ... Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53. ...

AJHG - Mutations in TOPORS Cause Autosomal Dominant Retinitis ...

TOPORS is a RING domain–containing E3 ubiquitin ligase and localizes in the ... The ubiquitous nature of TOPORS expression and a lack of mutant protein in ...

Protein can help cells or cause cancer, Purdue researcher finds

This is an official news Web page of Purdue University, home of the Boilermakers, ... Topors binds itself to p53 molecules during the ubiquitination process. ...

Retinitis Pigmentosa: Free Medical and Health Information on RP ...

Updated regularly: over 50 descriptions of the latest treatments for retinitis pigmentosa, from specialists in ... Mutations in the TOPORS gene cause 1 ...

The DNA topoisomerase I binding protein topors as a novel cellular ...

In this report we show that Topors, a Topoisomerase I and p53 interacting ... In a yeast two-hybrid system, Topors interacted with both SUMO-1 and the SUMO-1 ...

The topoisomerase I-binding RING protein, topors, is associated with ...

We previously identified topors as a topoisomerase I-binding protein that ... Additional studies indicate that topors, but not PML, rapidly relocalizes from ...
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