Daiichi Sankyo and Lilly Receive U.S. FDA Approval for Effient(TM)
...-TIMI 38 investigator Elliott Antman, M.D., professor of Medicine at Brigham and Women's Hospital (BWH) in Boston and senior investigator with the BWH timi Study Group. "Prasugrel is an important new option for patients with ACS who are managed with PCI. Prasugrel was associated with a significantly high...Schering-Plough Reports Financial Results for 2009 First Quarter
... Reported on a Phase II study published in The Lancet of the company's novel oral thrombin receptor antagonist (TRA), which showed no increase in timi major and minor bleeding and was well tolerated when given with standard platelet therapy. (Announced March 12) Initiated the first-in-human ...Prasugrel Receives Unanimous Approval Recommendation from FDA Advisory Committee
...am and Women's Hospital (BWH) in Boston and senior investigator with BWH's timi Study Group. "In a large head-to-head trial, TRITON, showed that prasugrel ...g was compared to the benefit of reduced heart attack, there were five more timi major bleeding events, but 22 fewer heart attacks for every 1,000 patients ...Phase II Trial of Experimental Anti-Coagulant Reports Safety and Outcomes Data
...spirin plus a thienopyridine. Regarding the safety endpoint, a composite of timi major bleeding, timi minor bleeding and any bleeding requiring medical attention, the researcher...Cholesterol-Lowering Drugs May Ease Irregular Heartbeat
...rofessor of medicine at Harvard Medical School and a cardiologist at Brigham and Women's Hospital, Boston. Cannon is also a senior investigator in the timi (Thrombolysis in Myocardial Infarction) Group, which has done studies on statins and atrial fibrillation. "It would be nice to see a larger number ...Ranexa(R) Significantly Reduces Ischemia in Women in MERLIN TIMI-36 Study
...atic documented arrhythmias was observed in women between the ranolazine and placebo groups. The data were presented today by Dr. Jessica Mega of the timi Study Group at the American Heart Association Scientific Sessions in Orlando, Florida. "Women were very well represented in the MERLIN TIMI-36 study ...New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel
...pectively (P=0.48). The results also showed that rates on non-CABG-related timi major or minor bleeding did not significantly differ by genetic variant amo...Physician at Brigham and Women's Hospital in Boston and Investigator at the timi Study Group. "We wanted to test if these genetic variants have a similar ef...Schering-Plough Announces Results of the Early ACS Trial
...bleeding were observed in the study group, with 118 patients experiencing a timi major bleeding event, compared to 83 in the delayed provisional group (p=0....us adverse events through 120 hours. Bleeding was measured according to the timi and GUSTO bleeding scales. About INTEGRILIN(R) (eptifibatide) Injecti...MGuard(TM) Coronary Stent System Approved in Israel
... with acute STEMI who received the MGuard stent with no additional distal embolization or aspiration device. The primary endpoint is ST resolution and timi flow, and follow up is up to six months. The study's primary endpoints are complete resolution of ST-segment elevation and restoration of flow through...Daiichi Sankyo and Lilly Respond to Speculation on Status of Prasugrel New Drug Application
...d risk of serious bleeding with prasugrel overall, some of which may be life threatening. Overall, for every 1,000 people treated, there were six more timi major bleeding events, but 23 fewer heart attacks in patients taking prasugrel compared with patients taking clopidogrel(i). The risk of cardiovascula...ATHENA Clinical Results with Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
... a landmark trial, that marks a paradigm change for the management of atrial fibrillation," said Prof Christopher Cannon, a Senior Investigator in the timi Study Group at Brigham and Women's Hospital, Harvard Medical School, who was not involved in the study. "Atrial fibrillation is a very common disease,...ATHENA Clinical Results for Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress
... a landmark trial, that marks a paradigm change for the management of atrial fibrillation," said Prof Christopher Cannon, a Senior Investigator in the timi Study Group at Brigham and Women's Hospital, Harvard Medical School, who was not involved in the study. "Atrial fibrillation is a very common disease,...Sanofi-aventis Announces Second Quarter 2009 Results
...the ACTIVE-I study evaluating irbesartan in patients with atrial fibrillation will be presented on September 1. Results from the SEPIA-ACS1 timi 42 phase II trial, evaluating the efficacy and tolerance of otamixaban (an intravenous selective anti Xa factor) in patients with acute coronary syndr...Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial
...rent heart attacks," said David A. Morrow, M.D. M.P.H., Associate Professor of Medicine at Harvard Medical School and a Senior Investigator with the timi Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA. Investigators classified 1,218 heart atta...Circulation Publishes MERLIN TIMI-36 Data Showing Safety and Anti-Arrhythmic Effects of Ranexa(R)
...i-arrhythmic agent in treating ventricular arrhythmias," said Benjamin Scirica, a cardiologist at Brigham and Women's hospital, an investigator at the timi Study group and lead author of the study. These data represent the first clinical report of the effect of ranolazine to reduce the incidence of cardi...