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TBP in Medical News

Singapore Reinforces Position as a Global Site for Pharma & Biotech; Biomedical Manufacturing Output Quadruples to Reach US$17 Billion

... for pharmaceutical and biologics manufacturing. tbp is currently home to leading pharmaceutical, biote... power, water supply, and telecommunication lines, tbp continues to attract leading biomedical sciences c... chilled water and waste treatment. In addition, tbp offers environmentally-friendly utility solutions ...

Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration

...ats interfere with the function of an essential transcription factor called tbp (TATA-box binding protein). In turn, the expanded polyQ sequence alters the interaction of tbp with other transcription factors, leading to neurodegeneration. Transcripti...
TBP in Biological News

Regulation of TATA-less promoters

...he other was the differential usage of TRF2 versus tbp within a gene cluster generally thought to be coor...TA box core promoter element that is recognized by tbp (the TATA-box binding polypeptide), the majority o...ent ones and a small class genes that utilize both tbp and TRF2. They show that TRF2 is used as an altern...

Muscle mass: Scientists identify novel mode of transcriptional regulation during myogenesis

... 1 print date at www.genesdev.org . For nearly 30 years, we have assumed that the basal transcription machinery, particularly the highly conserved tbp and TFIID complex, would be invariant and universal for all cell types in eukaryotes. It seems that this simplistic model will need to be revised wit...

An HIV Protein Plays a Surprising Role in Gene Activation

...lts show a surprising new role for Tat in stimulating assembly of a transcription complex. What's more, the complex lacks the TAFs typically linked to tbp in mammalian cells. Because their experiments analyzed only transcription complex assembly, the authors are careful to note that Tat may well stimulat...
TBP in Biological Technology

Separation and Comparison of Proteins From Virulent and Nonvirulent Strains of the Fish Pathogen Flavobacterium psychrophilum, Using a 2-D Electrophoretic Approach

...d (E2). Reagent 3 (5 M urea, 2 M thiourea, 2% CHAPS, 2% SB 3-10, 40 mM Tris and 0.2% Bio-Lyte 3/10 carrier ampholytes) with 2 mM tbp was then added to the pellet and the process repeated to obtain highly hydrophobic proteins generally associated with tightly bound membran...
TBP in Biological Products

Mouse Anti-TATA Binding Proteins (TBP) Monoclonal Antibody, Unconjugated, Clone ITBP20 from Covance Research Products, Inc

Description:...tibody ITBP20 was raised against recombinant human tbp and recognizes amino acids 41-57 and may be useful... in applications where N-terminal fragmentation of tbp occurs. This antibody does not inhibit the activity of tbp (prepared either as a nuclear extract or as a mini...
Company:Covance Research Products, Inc
TBP in Biological Dictionary

Polypeptide

..., wherein regulating activation of the classical ... Genesis of novel polypeptide domains by "exonization" of intronic sequences ... Evolution of tbp suggests insertion-based genesis of novel complex polypeptide domains ... ...
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