Patients Beyond Borders Thailand Edition to Launch in September
...national tourism industry and its related sectors. tat
also supplies information on tourist destinations ...ct travelers to Thailand.
For nearly 50 years, tat
has played a significant role in national tourism ...tions available. Thirty-five local and 22 overseas tat
offices disseminate Thailand tourism information w...
Bumrungrad Launches 2009 Great Chefs Program - Top local Chefs Design Menus Based on 'Amazing Thailand'
... CEO. "This year, we wanted to connect these expert chefs to what's special about Thailand--for example, great beaches and delicious seafood. The tat
campaign offers a natural tie-in."
The participating hotels include: Swissotel Le Concorde Bangkok, Pan Pacific Bangkok, Sofitel Centara Gran...
Study sheds light on causes of HIV dementia
...rasad and colleagues compared the sequences of the tat
protein of the two clades and noted a key difference. Where the clade B tat
protein contained the amino acid cysteine at a specific position in the tat
protein, the clade C...
Selenium may slow march of AIDS
...ey protein known as Tat, is the likely culprit.
is one of about 14 odd proteins produced by HIV du...at the virus needs to sustain itself. In addition, tat
also plays a key role in helping the virus replicate.
One of the proteins that targets tat
is a selenoprotein known as TR1.
"Since HIV ta...
Researchers identify toehold for HIV's assault on brain
... neurons. Researchers discovered the receptor that tat
uses to attack neurons, and they were able to reverse the effects of tat
in the laboratory by blocking the receptor.
Gelbard's team discovered that tat
works through the ryanodine receptor to sicken neu...
Illinois Radiologists Self-Edit Reports, Reduce Turnaround Time with SpeechQ for Radiology(TM)
...to the appropriate radiologist for review and signature. With
SpeechQ, average report turnaround time has been reduced from 61/2 hours to
3 hours, and tat
for STAT and ED reports is now five minutes.
Dr. James Studlo, medical director of Imaging Services and chief of the
medical staff at Provena Mercy,...
Anti-parasite drug may provide new way to attack HIV
...N. In a series of experiments, Kims team observed that the presence of HIV tat
in infected macrophages lowers PTEN levels by 40 percent, enabling the PI3K... inhibits PI3K/Akt pathway, and thus, promises to counter the effect of HIV tat
on PTEN, Kim said. The treatment was first identified in Germany in the ear...
amfAR announces inaugural Mathilde Krim Fellowship Awards for AIDS research
... cell protein, P-TEFb, which interacts with a segment of the virus called Tat. Dr. DOrso plans to elucidate the precise details of the process whereby tat
and P-TEFb bind together and the structure of these protein complexes. Understanding the process of assembly and the shape taken by these proteins whe...
FDA Approves New Roche West Nile Virus Blood Screening Test
...nce of a new threat to the U.S. blood supply. Although mosquito-borne
transmission remains the predominant mode of WNV transmission,
identification of tat
underscored the need for WNV screening of donated
blood. In June 2003, blood-collection agencies implemented investigational
WNV nucleic acid-amplific...
Working Up Potential Living Liver Donors
...acts on his or her psyche, decision and satisfaction, as well as on the outcome of the potential recipient.
Researchers, led by Professor Sheung tat
Fan of the University of Hong Kong, sought to analyze and report the experiences of donor workups at their center, which performs many more transplant...
High blood sugar's impact on immune system holds clues to improving islet cell transplants
... AUGUSTA, Ga. A biological tit for tat
may hold clues to improving the success of islet cell transplants intended to cure type 1 diabetes, according to a Medical College of Georgia scientis...
Researchers discover how stealthy HIV protein gets into cells
...gs appears this month in Angewandte Chemie.
protein transduction domain of the HIV virus has s...roperties. First, it is a tiny part of the overall tat
protein, containing only 11 amino acids. Second, a...components and are designed to keep things out.
is extremely good at getting through cell membrane...
Researchers reveal HIV peptide's possible pathway into the cell
...sts have known that a positively charged, 11-amino-acid chain of HIV (HIV-1 tat
protein) can do the nearly unthinkable X cross through the cell membrane. Sometimes referred to as an "arrow protein," HIV-1 tat
pierces the cell membrane and carries a cargo though the cell membrane.
Scientists find potential 'off-switch' for HIV virus
...ous studies by others, they have proposed that the tat
protein and the enzymes that modify it serve as a ...ecular Biology. "Understanding how to activate the tat
resistor to interrupt the reactions leading to vir...s in a loop. First, one of HIV's genes creates the tat
protein, which is part of the chemical signal for ...
HIV protein enlisted to help kill cancer cells
...ish Hospital. "A portion of the HIV protein called tat
can transport biologically active compounds into cells. tat
is small, but it can move massive molecules. You could almost hook tat
up to a train, and...
A simple feedback resistor switch keeps latent HIV from awakening
HIV's transcriptional activator, the tat
gene, is encoded in the HIV genome. Once tat
is transcribed, it can rapidly increase transcript...at ultimately lead to viral replication. Thus, the tat
protein acts like a molecular switch, making it a ...
Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients
The study looked at two proteins, called tat
and gp120, that are part of the virus that causes ...dy's lead author. HIV is the only virus that makes tat
and gp120, which are produced during its normal li...ents for this complication. According to Rumbaugh, tat
and gp120 are believed to cause dementia by reduci...
Random gene expression may drive HIV into hiding
...of HIV's replication machinery: a gene called Tat. tat
facilitates transcription of HIV's entire genome, ...eates a positive-feedback loop: If a little bit of tat
is around, then the HIV genome is transcribed effi...l, it is copied into DNA, and then a little bit of tat
is made before the virus integrates into the host ...
Ancient immune defense mechanism is no match for HIV-1
...n function as a suppressor of RNA silencing (SRS). tat
helps HIV-1 to elude the cell's natural RNAi defen...te animals," explains Dr. Jeang. "Our finding that tat
is an SRS also helps explain the long-standing bio...vation that when HIV-1 is engineered to be lacking tat
but contains alternative transcriptional activator...
An HIV Protein Plays a Surprising Role in Gene Activation
... work with human cell lines and find evidence that tat
can also stimulate PIC assembly.
While most transcription factors bind to DNA, tat
binds to an area at the end of newly emerging vira...ransactivation response element (TAR). Once bound, tat
recruits a cellular complex called P-TEFb (consist...