Relaxation training may improve control of hard-to-treat systolic hypertension
Adding the relaxation response, a stress-management approach, to other lifestyle interventions may significantly improve treatment of the type of hypertension most common in the elderly. Among participants in a study conducted at the Massachusetts General Hospital (MGH) Hypertension Program and t...
Young Kids' Screen Time May Raise Blood Pressure
...edentary activity was not significantly related to systolic
blood pressure [the top number in a reading] or di...computer use, were positively associated with both systolic
blood pressure and diastolic blood pressure after ...t amount of TV and screen time had lower levels of systolic
and diastolic blood pressure than kids with the hi...
Millions Of U.S. Children Low In Vitamin D
...deogames, or using computers.
The researchers also found that low levels of vitamin D deficiency were associated with poor bone health, higher systolic
blood pressure, and lower calcium levels and HDL (good) cholesterol levels, which are key risk factors for heart disease.
"We expected the prev...
High-Salt Diet Dampens Effects of Blood Pressure Drugs
Those on the low-salt diet had an average drop of 22.7 points in systolic
blood pressure (the higher of the 120/80 reading, measured when the heart i...5 grams a day, the average reduction in a six-week period was 4.8 points in systolic
pressure and 2.2 points in diastolic pressure.
Both studies emphasize th...
Five Hypertension Genes Found in Black Americans
...e variants have been found to be associated with high blood pressure in the general population, he said.
All five variants are associated with high systolic
pressure, the higher of the reading, the pressure when the heart contracts, Rotimi said.
The study is important because "it is one of only a very f...
Vegetable Amino Acid Lowers Blood Pressure
... shows that a 4.72 percent higher intake of glutamic acid as a portion of total dietary protein correlates with a 1.5- to 3-point reduction in average systolic
blood pressure (the higher of the two blood pressure readings, when the heart beats) and a 1- to 1.6-point lower diastolic pressure (the lower reading...
Patients with lower urinary tract symptoms more likely to suffer from metabolic syndrome
...ter). In this analysis MetS was defined as the presence of three or more of the five characteristics of 1) waist circumference greater than 102 cm; 2) systolic
blood pressure 130 mm Hg or greater or diastolic blood pressure 85 mm Hg or greater, or antihypertensive medication use; 3) HDL cholesterol less than ...
Calling All Heart Patients
... 30 percent lower death rate than patients without the interventions. The telehealth patients also had lower total cholesterol levels, lower levels of systolic
blood pressure and lower rates of smoking.
The study appears in the June issue of the European Journal of Cardiovascular Prevention & Rehabili...
Researchers compare different systems of measuring treatment intensity in hypertension care
...whether these three scores could predict the final systolic
blood pressure and discovered that the any-or-none...control.
"The norm-based method did not predict systolic
blood pressure in a linear fashion. Further invest...aped relationship between the norm-based score and systolic
blood pressure," said lead author Adam Rose, MD, M...
Results from 8 late-breaking clinical trials presented at Heart Failure 2009
A multicentre study of a new inotropic drug (which increases the contraction and pumping of the heart), CK-1827452, found that it increases systolic
function in stable heart failure patients and was well tolerated in a proof of concept study. CK-1827452 is a new drug in a class known as Selective ...
Systolic in Medical Technology
Benicar HCT Reductions in Seated Systolic Blood Pressure for Stage
2 Patients Compared With Amlodipine + Benazepril
Comparison of BENICAR HCT 40/12.5 and 40/25 mg/day and Amlodipine +
Benazepril 5/20 and 10/20 mg/day Presented at American Society of
Hypertension Twenty-Second Annual Scientific Meeting
PARSIPPANY, N.J., May 21, 2007 /PRNewswire/ -- New data
presented today at the American Society of Hypertension...
FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent
...rapy) and followed for blood pressure response. The combination of Tekturna and hydrochlorothiazide resulted in additive placebo-adjusted decreases in systolic
and diastolic blood pressure at trough of 10-14/5-7 mmHg at doses of 150-300 mg/12.5-25 mg, compared to 5-8/2-3 mmHg for Tekturna 150 mg to 300 mg and...
Rigel's R788 Significantly Improves Rheumatoid Arthritis in Phase 2b Clinical Trial
...23/76 125/77 125/78
Change from Baseline to
Month 6 (LOCF) -1.8/+0.4 +0.2/+0.3 +0.6/+1.4
BP if had Adjustment or Initiation of BP Medication (mmHg)
# Had BP Meds Adjusted/Initiated 11 (7%) 27 (18%) 35 (23%)
New Heart Ultrasound Research Reveals Life-Saving Treatment Alternatives and Advancements for Heart Patients
...three-dimensional echocardiography technology.
Physicians can use echocardiograms, or heart ultrasound, to view the heart's left ventricular end systolic
volume (this measurement refers to the volume of blood in the ventricle immediately after the contraction of the heart) and ejection fraction, (a meas...
Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009
... Improvements in systolic
Blood Pressure and Triglycerides Also Observed
...ntrol with weight loss, as well as improvements in systolic
blood pressure and triglycerides, through two year...improved, and there was a significant reduction in systolic
blood pressure (SBP).
"These two-year DURATI...
Arena Pharmaceuticals Announces Lorcaserin Data Demonstrating Highly Significant Categorical and Absolute Weight Loss and Improvements in Secondary Endpoints Associated with Cardiovascular Risk
...t improvements compared to placebo in multiple secondary endpoints associated with cardiovascular risk, including:
Blood Pressure: systolic
blood pressure, diastolic blood pressure and heart rate
Lipids: total cholesterol, LDL cholesterol and triglycerides
Ongoing Landmark ROADMAP Study Demonstrates Significant Improvement in Blood Pressure Control at One Year, According to Blinded Results
...36.2/80.6 mm Hg. In the 4,013 patients who remained on double-blind treatment with either olmesartan medoxomil therapy or placebo after one year, mean systolic
BP reduction was 9.4 mm Hg, though responses were highly dependent on JNC 7 stages at outset. The ROADMAP study also showed a decrease in the prevalen...
New Data Shows Blood Pressure Reduction Therapy with BENICAR(R) and BENICAR HCT(R) Effectively Reduces Blood Pressure in Elderly Patients to Target Blood Pressure
...R (R) and BENICAR HCT (R) provided a mean reduction in 24-hour ambulatory systolic
blood pressure (SBP) of 25.7 mm Hg among patients with an average age of 72...Hg and mean baseline seated BP was 165.5/87.7 mm Hg, indicating predominant systolic
hypertension in this elderly patient cohort with a mean age of 71.9 years a...
New Data Shows AZOR(R) (amlodipine and olmesartan medoxomil) Significantly Improves 24-Hour Ambulatory Blood Pressure
...men provided mean 24-hour ambulatory reductions in systolic
blood pressure (SBP) of 21.4 mm Hg and diastolic b... AZOR 10/40 mg provided a mean reduction in seated systolic
blood pressure (SeSBP) of 24.6 mm Hg and the seate...xclusive). The primary endpoint was change in mean systolic
blood pressure (SBP) from baseline after 12 weeks ...
Data from Phase 2 Study of Peramivir in Patients Hospitalized with Influenza Presented at the XI International Symposium on Respiratory Viral Infections
... to evaluate time to clinical stability, which is a composite endpoint comprised of normalization of temperature, oxygen saturation, respiratory rate, systolic
blood pressure and heart rate. This type of endpoint has previously been used in pneumonia studies, but not in influenza. Secondary objectives of th...
Systolic in Medical Products
SphygmoCor Mx Central Blood Pressure Monitoring System
Description:...iastolic, and Pulse Pressures
Augmentation Index a measure of the clinical impact of arterial stiffness on the heart
Ejection Duration systolic
timing, and hence an indicator of myocardial demand
Subendocardial Viability Ratio a measure of cardiac reserve
The SphygmoCor Mx Syst...
Company:AtCor Medical Pty Ltd.
SphygmoCor Vx Central Blood Pressure/Pulse Wave Velocity System
Description:...f 30 and 60. Pulse Wave Velocity
Arterial stiffness is a major cause of cardiovascular disease. Increases in arterial stiffness increase central systolic
& pulse pressure, and demand on the left ventricle, and decrease the perfusion pressure through the coronary arteries, thereby increasing the risk of ...
Company:AtCor Medical Pty Ltd.
AutoCAT 2 WAVE Series Intra-Aortic Balloon Pump
Description:...itions. One button start up initiates counterpulsation in 1:1 assist at full catheter volume with correct timing indices to optimize augmentation and systolic
unloading. Low cost of ownership with no routine replaceable parts....
Company:Arrow International, Inc.
Triage BNP Test
Description:...c hormone produced by the heart ventricles in response to ventricular volume expansion and pressure overload. Excellent hormonal marker of ventricular systolic
and diastolic dysfunction. The Triage BNP Test provides meaningful diagnostic information not available
from other clinical assessments....
Ocular Blood Flow Analyzer (BFA)
Description:...es and falls with each heartbeat. This pressure waveform is created when the bolus of blood from each heartbeat passes through the ocular choroid. The systolic
increase and diastolic decrease in intraocular pressure caused by the pulsatile ocular blood flow is accurately recorded by the BFA. This data is anal...
Company:Paradigm Medical Industries, Inc.
Carbo-Seal Valsalva Ascending Aortic Prosthesis
Description:... Carbo-Seal Valsalva AAP is the first valved graft to replicate the natural Sinus of Valsalva, encouraging the natural formation of systolic
Tango Exercise Stress BP Monitor
Description:... The Tango exercise BP monitor is designed to automatically measure and display your patient's systolic
and diastolic BP along with heart rate. It's a Blood Pressure monitor designed specifically for use in treadmill, ergometer and pharmacological stress...
Portable ABI Kit
Description:...pressure index (also known as the Ankle/Brachial Index or ABI) compares the systolic
blood pressure of the ankle to that of the arm (brachial). These measuremen... Doppler or pulse volume waveform analysis. Significant changes in arterial systolic
pressure between sites indicate reduced blood flow caused by obstruction of...
SphygmoCor Px Central Blood Pressure Assessment and Management System
Features:...ressure, and hence the risk of stroke.
pressure, often markedly different from the cuff v...duration a parameter for distinguishing primarily systolic
from primarily diastolic dysfunction, and for mana...), a key determinant of coronary blood supply.
pressure-time index (SPTI), a measure of myocardia...
Company:AtCor Medical Pty Ltd.
Features:...stolic pressure and retrograde aortic flow increase myocardial perfusion
unloading reduces cardiac workload and oxygen requirements
Increased venous return, coupled with enhanced systolic
flow, increases cardiac output ...
Systolic in Medical Definition
Ambulatory blood pressure
Based on American Heart Association D i p = 1 − f r a c ( s l e e p S B P )( A w a k e S B P ) * 100%
SBP => systolic
0% - 10%
10% - 20%
Systolic in Medical Dictionary
..... systole ... extrasystole - a premature systole resulting in a momentary ... ... BZ region during isovolumic systole but preserved overall systolic
... A selected short axis slice at (B) end-diastole and (C) end- systole is demonstrated. ... Unbound MEDLINE | Systole journal articles. Searc...
... blood pressure can be found at ... Treated patients are less likely to develop severe hypertension or congestive heart failure. ... Isolated systolic
hypertension , defined as a blood pressure of ... Hypertension is rapidly increasing and relatively neglected problem in Nepal. ... The Socie...
...ding symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. Hypertension is defined as the sustained elevation of either or both systolic
... Hyperinsulinemia can be caused by insulin resistance, which creates elevated ... Original Article from The New England Journal of Medicine...
...;s Medical Dictionary ... Heart Murmurs in Pediatric Patients ... Heart murmurs are most often caused by defective heart valves. ... A systolic
(sis-TOL'ik) murmur occurs when the heart muscle contracts. ... A heart murmur is an extra or unusual sound heard during a heartbeat. .....
Systolic in Biological News
Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes
...ng diminished LV wall thickness in both diastole and systole, increased end systolic
LV dimensions, depressed fractional shortening, a greater impairment of LV ...panied by increased fibrosis and functional derangements indicative of both systolic
and diastolic dysfunction. Dr. Sobel said that "in concert with our previo...
Grapes may aid a bunch of heart risk factors, animal study finds
...ucing blood pressure.
The rats in the high-salt grape and high-salt hydrazine groups did develop high blood pressure over time, but they had lower systolic
blood pressures than the high-salt rats that did not receive grapes.
The researchers also measured the distortion of the heart size, weight and fu...
Chocolate bar shown to lower cholesterol
...by eating chocolate bars.
Eating two CocoaVia dark chocolate bars a day not only lowered cholesterol, it had the unexpected effect of also lowering systolic
blood pressure, said John Erdman, a U. of I. professor of food science and human nutrition.
The study, funded in part by Mars Inc., the company tha...
Energy drinks may pose risks for people with high blood pressure, heart disease
Within four hours of energy drink consumption, maximum systolic
blood pressure (the top number that represents pressure while the heart con...tion of the study, heart rates increased five to seven beats per minute and systolic
blood pressure increased 10 millimeters of mercury (mmHg) after energy drin...
Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
...ction two days post infarct. On average, left-ventricular end diastolic and systolic
diameters increased by 10% and 42%, respectively, and fractional shortening...yocyte-treated rats compared to controls, as well as a 2.5-fold increase in systolic
wall thickening in the infarct zone relative to controls (0.01).
8 plants from South Africa may hold potential for treating high blood pressure
...human patients 5-14 hours after the dose with no significant side effects. In addition, wild and cultivated garlic preparations were shown to decrease systolic
blood pressure in rats.
In this study Tulbaghia violacea has shown properties related to lowering blood pressure. Since the n...
Sex and the heart: It's not what you think
... representative samples of the US population, approximately 10 years apart.
Among the findings:
High risk blood pressure - both diastolic and systolic
- increased in women but decreased in men. Medication against hypertension appeared to be more effective in men than women.
Both men and women...
Walking not enough for significant exercise benefits
...d that the traditional fitness program improved aerobic fitness and reduced systolic
blood pressure, more than the 10,000-step lifestyle program," Dr. Harber sa... who took part in the walking program experienced a four per cent increase. systolic
blood pressure also dropped by 10 per cent for the traditional fitness grou...
Systolic in Biological Technology
PeriCor Therapeutics Reports Positive Preclinical Results of GP531 at the European Heart Failure Congress in Nice
...e" found that an acute intravenous infusion of GP531 at doses ranging from 3 mcg/kg/min to 300 mcg/kg/min significantly improves left ventricular (LV) systolic
function. GP531 treatment, as compared to placebo, increased ejection fraction and decreased LV end-diastolic pressure, end-diastolic volume and end-s...
Amgen Exercises Option for Exclusive License to Cytokinetics' Cardiac Contractility Program That Includes CK-1827452
...rrent drugs also increases the velocity of cardiac contraction and shortens systolic
ejection time. In contrast, cardiac myosin activators have been shown to w...n the velocity of cardiac contraction, but instead, in a lengthening of the systolic
ejection time, which results in increased cardiac contractility and cardiac...
First oral uveitis drug reduces both inflammation and recurrence in potentially blinding eye disease
...y (8.2% of subjects with decrease from baseline by ≥30% in glomerular filtration rate vs. 4.1 % in placebo) and blood pressure (mean increase in systolic
BP by 6 mm Hg) will require monitoring, but were overall moderate and manageable. Triglycerides and cholesterol were not elevated and had no negative ...
Amorcyte Reports Phase I Results of AMR-001 to Improve Recovery From Severe Heart Attack at ACC Annual Scientific Session
... blood pumped out of a ventricle with each heartbeat, (+4% versus +1%); end systolic
volume (-5.7mL versus -0.1mL); and infarct size, tissue death due to loss o...erapy after AMI, showed a significant improvement in ejection fraction, end systolic
volumes, infarct size, reduction in subsequent MI's, and trends towards red...
Financial Results for Full Year 2008: NicOx in a Unique Position to Deliver Significant Shareholder Value
...f naproxcinod showed a similar blood pressure profile to
placebo, as indicated by one-sided 95% confidence intervals (CIs). Naproxen
500 mg bid raised systolic
blood pressure (SBP) by 2.0 mmHg compared to
placebo, in terms of the mean change between baseline and the average over
weeks 2, 6 and 13. Further ana...
Traditional Risk Factors Often Miss Heart Disease Warning Signs
...se (CHD) and who had a low Framingham risk score. The risk factors included in the Framingham calculation are age, total cholesterol, HDL cholesterol, systolic
blood pressure, treatment for hypertension and cigarette smoking. Patients with existing CHD or CHD equivalents were excluded.
The most common e...
Synvista Therapeutics Announces Progress in Phase 2 Clinical Trial Program for Alagebrium
...ium on exercise tolerance in patients with chronic systolic
heart failure. In addition, the Company anticipate...n approvable regulatory endpoint, in patients with systolic
or diastolic heart failure. Accordingly, we look f...ycation endproducts (A.G.E.s) for the treatment of systolic
and diastolic heart failure.
For more infor...
FDA Approves Boston Scientific's Express(R) SD Renal Stent System
...ress SD Renal Stent in
hypertensive patients with atherosclerotic renal artery stenosis (RAS),
demonstrated a statistically significant improvement in systolic
pressure and no statistical difference in either diastolic blood pressure or
serum creatinine levels from baseline through three years(1). Nine...
Synvista Therapeutics Announces 510(k) Submission for Its HAPTOCHEK(TM) Test Kit
...nts in the United States. The Company is also developing alagebrium, a proposed breaker of advanced glycation endproducts (AGEs) for the treatment of systolic
and diastolic heart failure.
For more information, please visit the Company's Web site at www.synvista.com .
Any statements ...
NicOx' Naproxcinod Shows Highly Significant Reduction in Daytime Blood Pressure Versus Naproxen
This new post hoc analysis was accepted by the American Heart
Association scientific panel and compared the mean 24-hour systolic
pressure (SBP) as measured by ABPM in the two groups (i.e. naproxcinod vs.
naproxen), at the end of the 2 weeks of active treatment. The mean 24...
Systolic in Biological Definition
... have unexplained bleeding from the mucous membranes , skin , eyes , or gastrointestinal tract . The patient may also be going into shock (has a systolic
blood pressure of less than 90 mm Hg or a rapid weak pulse). Finally, that patient may have had contact with someone in the last three weeks tha...
Systolic in Biological Dictionary
...ology and understanding the MAP with its correlations. ... Thus, the arterial system works like a hydraulic filter and lessens the ... ... the systolic
ejection in the arterial system followed by a gradual release during diastole. ... driving pressure is that in the arterial system and the end...