Genes In The Interferon System Important In Systemic Lupus Erythematosus
Two genes with very strong associations withthe disease systemic lupus erythematosus (SLE) have been identified bya team of scientists headed by researchers at the Department of MedicalSciences at Uppsala University. The findings are being published todayon the Web page of the highly prestigious American Journal of HumanGenetics. "These findings are probably the first genetic pieces of ahug...Fox Chase Cancer Center scientists identify immune-system mutation
A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
New York University biologists have uncovered how the innate immune system in mice's brains fights viral infection of neurons. The findings, published as the cover study in the latest issue of Virology, show that proteins in neurons fight the virus at multiple stages--by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brai...Transport System Smuggles Medicines Into Brain
Parrots, long a favorite pet animal, are attractive to owners because of their vibrant colors. But those colors may mean more to parrots than what meets the eye. For more than a century, biochemists have known that parrots use an unusual set of pigments to produce their rainbow of plumage colors, but their biochemical identity has remained elusive. Now, an Arizona State University researc...Open microfluidic and nanofluidic systems
The labs of the future will be "labs-on-a-chip", i.e., integrated chemical and biochemical laboratories shrunk down to the size of a computer chip. An essential prerequisite for such labs are appropriate microcompartments for the confinement of very small amounts of liquids and chemical reagents. Directly accessible surface channels, which can be fabricated by available photolithographic methods,...R.A.P.I.D. System from Idaho Technology Inc.
Description:Idaho Technologys R.A.P.I.D. System (Ruggedized Advanced Pathogen Identification Device) is a rugged, real-time, PCR thermocycler designed for field hospitals, mobile laboratories and other rough environments. In addition to its ruggedness, it is designed with the same sensitivity and specify as the LightCycler instrument. By taking advantage of thin-walled capillary tubes, the R.A.P.I.D. is able...CEQ 8800 Genetic Analysis System from Beckman Coulter
Description:The CEQ 8800 Genetic Analysis System, which processes two 96-well plates and tracks the samples. This automated system adds a higher level of throughput to the CEQ product line. The CEQ 8800, part of Beckman Coulters new GenomeLab family of products*, also offers a bar coding link with the Biomek series liquid handers, for increased automation. The CEQ 8800 automates and integrates the majo...ProteomeLab PA 800 Protein Characterization System from Beckman Coulter
Description:The ProteomeLab PA 800 is an automated, high-resolution protein analysis system. Part of Beckman Coulters ProteomeLab family of products, the PA 800 offers a comprehensive range of automated protein characterization solutions including molecular weight determination, peptide mapping, isoelectric focusing, carbohydrate profiling and mechanisms to study protein/protein interactions in solution. B...ProteomeLab PF 2D Protein Fractionation System from Beckman Coulter
Description:The ProteomeLab PF 2D is an automated, two-dimensional fractionation system for high-resolution analysis of complex protein mixtures. Part of Beckman Coulters ProteomeLab family of products, the PF 2D produces results in just hours. The system effectively resolves the thousands of proteins present in cell lysates, addressing a key challenge in todays proteomics research.In the first dimension,...pET GST Fusion System 42 plus Competent Cells from Novagen
Description:Schistosomal glutathione-S-transferase (GST) is commonly used as a fusion partner when expressing proteins in E. coli (1). The GSTTag sequence has been reported to enhance the production and in some cases the solubility of its fusion partners. When expressed in a soluble, properly folded form, GSTTag fusion proteins can be purified with immobilized glutathione. Gentle elution is achieved with buf...New Mammalian Two-Hybrid System Detects Protein-Protein Interactions
Stratagene hybrid genes are used to detect protein-protein interactions via the activationof reporter gene expression. This expression occurs as a resul...Assess the In Vivo Activation of Signal Transduction Pathways with PathDetect Reporting Systems
Assess the In Vivo Activation of Signal Transduction Pathways withPathDetect Stratagene Signal transduction is essential to many cellular processes, such asgrowth, differentiation, an...New Yeast Cloning System for Producing Proteins with Native Amino Acid Sequences
Stratagene Cloning Systems, Inc. The ESP LIC cloning and expression system features rapid and high-yieldproduction of recombinant proteins in yeast. This system usesligation-independent cloning (LIC) for efficient and dire...Passive smoking affects respiratory system
Scientists have produced strong evidence that passive smoking has a lasting impact on the respiratory systems of children. A team from the US National Center for Environmental Health in Atlanta studied data from 3,400 children aged 3 to 16 years. The researchers analysed the children's blood to determine the concentration of a substance called cotinine, produced when the b...Tumor Suppressor p53's Contradictory Regulatory System
A new study appearing in the online open-access journal PLoS Biology examines the role played by the tumor suppressor protein called p53. It has been found that any mutations of p53 play a key role in the development of many human cancers. //This particular study was carried out by Min Hu, Yigong Shi and colleagues. To provide a bit of background, when there a cell injury, p53 triggers...Early Warning System For Breast Cancer
A tiny protein called RhoC found in breast tumors may someday give doctors and patients an early warning system that could spot dangerously aggressive breast cancer long before it begins to spread, and identify the need for aggressive treatment.// A test to detect the protein is still more than a year away from clinical trials. But promising early results show that RhoC can serve as a mar...Gene connected to Multi-System disorder discovered
A complex and rare disorder that affects many systems of the body, called oculodentodigital dysplasia, has been found to be the result of faulty cell communication. This syndrome is said to affect various body structures including the eyes, face, teeth and fingers and can also cause hearing loss, heart trouble// and neurological problems. A Hopkins-led research team, which studied the gen...Silicone Oil Cannula System - 20 Gauge
Description:20 gauge x 8 mm with 15 cm high pressure extension tube preattached to a 10C ring control syringe. 3 per box....Silicone Oil Cannula System - 19 Gauge
Description:19 gauge x 8 mm with 15 cm high pressure extension tube preattached to a 10C ring control syringe. 3 per box....When Volume Matters, Immunoassay Systems Deliver
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...Genetic Analysis Systems Enter the Clinical Mainstream
Like many other diagnostic regimes that were previously restricted to large specialty laboratories, genetic analysis is entering the clinical mainstream. Smaller, simpler analyzer systems are now suitable and affordable for hospital or large physicians group labs, while some genetic test kits are becoming available for primary point of care locations such as clinics and physician offices.<...New Quality Control Systems for Every Laboratory Application
Quality Control (QC) materials and procedures are key to meeting the needs of doctors and patients by verifying accuracy and precision of analytical methods. Vendors of these systems can be a valuable resource, designing customized QC materials and protocols to help lab managers ensure that analytical error st...Immunoassay Systems - Your Laboratory Workhorse
Although new and innovative technology has enabled more and more laboratory testing to occur at the bedside or physicians office, the central laboratory is hardly threatened with extinction. National volume data suggest that medium and large labs are busier than ever before, and the huge range of their capabilities, gold standard reliability and ability to handle very large volumes of tests a...Ultrasound-enhanced systemic thrombolysis
) to treat stroke-causing blood clots. It is thought that transcrania...