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Stanford researchers synthesize compound to flush HIV out of hiding

Any hunter will tell you that when your quarry goes into hiding, you have to flush it out to get a good shot at it. Such is the case with HIV, the virus that causes AIDS. Though antiretroviral "cocktails" can target an active infection, they cannot get at the virus when it retreats inside the h...

'Hen Factories' To Synthesize Cancer Drugs

'Most of the important things in the world have been accomplished by people who have kept on trying when there seemed to be no hope at all.' ??????????????????????……… Dale Carnegie A groundbreaking venture has been initiated// by a group of researchers, whereby therapeutic proteins, e...

Neuronal survival and axonal regrowth obtained in vitro

...rmally, the primary role of astrocytes is to supply the nutrients necessary for neuronal function. In the event of spinal injury or lesion, astrocytes synthesize two particular proteins (glial fibrillary acidic protein (GFAP) and vimentin), which isolate the damaged neuron to prevent interference with the opera...

Kaiser Permanente Wins National Award for Technology-Supported Patient Care and Efficiency

...ation-based total joint replacement registry, with data on more than 75,000 joint replacement surgeries - making it possible to conduct, evaluate, and synthesize research into actionable clinical-care guidelines. Breast cancer screening . In 2008, Kaiser Permanente's Southern California region ranked #1...

Understanding the process of homosexual identity formation among Asian and Pacific Islander youth

...e stereotypes and assumptions related to their ethnic identity. Still others sublimate their sexual identify and appear asexual until they are able to synthesize an identity that incorporates both ethnicity and sexuality. The researchers developed an API sexual minority model that simultaneously explores s...

Researchers identify individuals at risk for developing colon cancer

...who are born with mutations that cause defects in the pathways that put sugar groups on proteins. The normal process, called glycosylation, is used to synthesize mucus and is involved in many cellular activities. The individuals with this genetic defect appeared to develop colon cancer later in life. Data was ...
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CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

... swine flu and other H1N1 flu viruses." L.E.A.P.S. technology is a novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or autoimmune disea...

Rib-X Pharmaceuticals Novel Antibiotic Delafloxacin Named One of R&D Directions 100 Great Investigational Drugs of 2009

... state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibi...

ELAD(R) Liver Support System Study Initiated at Multiple U.S. Centers

... The patient's plasma flows inside of the hollow fibers to allow two-way transfer of metabolites. During ELAD therapy the cells metabolize toxins and synthesize proteins and other liver specific products essential for life. The ELAD cell cartridges are produced at VTI's GMP-compliant facility in San Diego, Cal...

Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin

... state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibi...

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Next Generation Oxazolidinone at 2008 ICAAC/IDSA Joint Meeting

... state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibi...

Data Suggest CEL-SCI's CEL-2000 Vaccine Prevents or Retards Permanent Damage of Rheumatoid Arthritis

...nd Epitope Antigen Presentation System) technology. L.E.A.P.S.(TM) is a novel T-cell modulation platform technology that enables CEL-SCI to design and synthesize proprietary immunogens. Any disease for which an antigenic sequence has been identified, such as infectious, parasitic, malignant or autoimmune diseas...
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ACCF Clinical Trials Database

Description:... This is designed to synthesize current cardiovascular research findings for busy physicians and healthcare professionals....
Company:Skyscape, Inc.

Follicle-Stimulating Hormone (FSH) Enzyme Immunoassay Test Kit

Description:... Follicle-Stimulating Hormone (FSH) is intimately involved in the control of the growth and reproductive activities of the gonadal tissues, which synthesize and secrete male and female sex hormones. The levels of circulating FSH is controlled by these sex hormones through a negative feedback relationship....
Company:Diagnostic Automation, Inc.
Synthesize in Medical Definition

Medicine

...ther data ( medical history , systems enquiry, and physical examination , combined with laboratory or imaging studies (investigations)) analyze and synthesize that data (assessment and/or differential diagnoses), and then: develop a treatment plan (further testing, therapy, watchful observation, referral a...
Synthesize in Medical Dictionary

Vitamin B6

...t vitamin B6 ? ... Linus Pauling Institute at Oregon State University ... Vitamin B6 must be obtained from the diet because humans cannot synthesize it. ... Vitamin B6 is the term for three related compounds, pyridoxine, pyridoxal and ... Deficiency of vitamin B6 in adults results in ch...

Urea nitrogen

...causes of increased and decreased blood urea nitrogen concentrations. ... ... urea or other nonprotein nitrogen -containing substances to synthesize protein, ... Thus, a nonprotein source of nitrogen , such as urea , may be fed to ruminants to ... ... blood urea nitrogen concentration, ...

Exocrine glands

...em ... The secretion cells of the Exocrine glands surround the beginning of ducts. ... The kind of exocrine glands found on the pancreas synthesize several digestive ... Accessory organs: various exocrine glands . • Digestive Processes. – Ingestion ... Exocrine Pancreas. • structure: comp...

Electrolytes

... activities and are vital to the function ... Another factor is an adequate intake of electrolyte -containing foods. ... These bacteria help to synthesize electrolytes in the colon. ... Salts such as sodium, potassium, calcium, and chloride are examples of electrolytes . ... Furosemide causes ce...
Synthesize in Biological News

Singapore scientists synthesize gold to shed light on cells' inner workings

Highly fluorescent gold nanoclusters for sub-cellular imaging have been synthesized by researchers at the Institute of Bioengineering and Nanotechnology (IBN), one of the research institutes of Singapore's A*STAR (Agency for Science, Technology and Research). Measuring less than 1 nanometer in...

ASU researchers synthesize molecule with self-control

TEMPE, Ariz. Plants have an ambivalent relationship with light. They need it to live, but too much light leads to the increased production of high-energy chemical intermediates that can injure or kill the plant. The intermediates do this because the efficient conversion of sunlight into chemi...

Chemists synthesize molecule that helps body battle cancers, malaria

The first synthesis of QS-21A, a medicinally important molecule that helps the body battle disease, has been achieved by chemists at the University of Illinois at Urbana-Champaign. In clinical trials, QS-21A has been shown to significantly improve the body's immune response in vaccine therapies ...

Navigating in the ocean of molecules

... promising characteristics as the starting point in the quest for new active agents: chemists can then vary the scaffolds with different appendages to synthesize the optimal active agent. Scaffold Hunter can also be used to predict bioactive molecules that do not arise in nature but are very likely to display s...

Munich researchers discover new target for tailored antibiotics

... Mnchen, and their research team have described in detail the structural basis for just such a reaction step. The cells of virtually all life forms synthesize essential natural substances belonging to the class of terpenes and steroids from the small isoprene building blocks dimethylallyl pyrophosphate (DMAP...

Facile synthesis of nanoparticles with multiple functions advanced in Singapore

...d consumer applications. Singapore's Institute for Bioengineering and Nanotechnology (IBN) has discovered a new environmentally friendly method to synthesize a wide variety of nanoparticles inexpensively. This new chemical synthesis has been recently published in Nature Materials . IBN researchers have ...
Synthesize in Biological Technology

Scientists synthesize memory in yeast cells

BOSTON, Mass. (September 14, 2007)Harvard Medical School researchers have successfully synthesized a DNA-based memory loop in yeast cells, findings that mark a significant step forward in the emerging field of synthetic biology. After constructing genes from random bits of DNA, researchers in ...

Scientists synthesize memory in yeast cells

BOSTON, Mass. (September 14, 2007)Harvard Medical School researchers have successfully synthesized a DNA-based memory loop in yeast cells, findings that mark a significant step forward in the emerging field of synthetic biology. After constructing genes from random bits of DNA, researchers in ...

Rapidly Synthesize Large Amounts of Capped RNA

Convenient format - premixed cap analog and nucleotides provided Optimized for highest yield of capped RNA 80% capping efficiency Complete with SUPERaseIn RNase inhibitor, DNase I, and ...

DOE awards $377 million in funding for 46 energy frontier research centers

... use as materials to convert solar energy and heat to electricity. University of North Carolina (Chapel Hill, NC) $17.5 million for five years to synthesize new molecular catalysts and light absorbers and integrate them into nanoscale architectures for improved generation of fuels and electricity from sunl...

Rib-X Pharmaceuticals Reports Positive Phase 2 Study Results for Radezolid in Community-Acquired Pneumonia

... state-of-the-art, proprietary computational analysis, X-ray crystallography, medicinal chemistry, microbiology and biochemistry, allows it to rapidly synthesize new agents designed to avoid typical antibiotic resistance mechanisms. Rib-X's iterative intelligent engine has yielded several distinctive new antibi...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... that could be used to target diseases that until now have stymied drug developers, such as Parkinson's disease. This technique uses baker's yeast to synthesize and screen the molecules, cutting target discovery and preliminary testing time to a matter of weeks. The current drug discovery process is arduo...
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Mouse Anti-Human Complex IV, assembly factor SURF1 Monoclonal Antibody, Unconjugated, Clone 21H2BG4 from MitoScience LLC

Description:... structural subunits of the enzyme SURF1 is significantly over-expressed. This is evident in Rho0 fibroblasts which are missing mtDNA and hence cannot synthesize subunits I, II and III of cytochrome c oxidase....
Company:MitoScience LLC

MAXIscript SP6/T7 Kit from Ambion

Description:... Ambions MAXIscript In Vitro Transcription Kits synthesize RNA probes with specific activities reaching 1 x 10 9 cpm/g. High specific activity, single-stranded RNA probes are used in ribonuclease protection a...
Company:Ambion

MultiScribe Reverse Transcriptase from Applied Biosystems

Description:...e. MuLV reverse transcriptase is a recombinant RNA-dependent DNA polymerase that uses single-stranded RNA as a template in the presence of a primer to synthesize a complementary DNA (cDNA) strand. The PCR process and 5' nuclease process are covered by patents owned by Roche Molecular Systems, Inc. and F. Hoff...
Company:Applied Biosystems

Custom Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences

Description:...your samples against thousands of possible substrate sequences for discovery, or zero in on known substrates to generate binding curves. We can easily synthesize all possible variants of your known sequences of interest or perform sequence tiling. High-Throughput Format Traditional kinase assays focus on a s...
Company:LC Sciences

Custom Epitope Peptide Microarray from LC Sciences

Description:...een your samples against thousands of possible epitope sequences for discovery, or zero in on known epitopes to generate binding curves. We can easily synthesize all possible variants of your known sequences of interest including N-truncation, C-truncation, sequence tiling, and more. LC Sciences can provide ass...
Company:LC Sciences

Human / Mouse / Rat Blood Vessels (CD31 / Von Willebrand Factor (vWF)) IHC staining Kit from CHEMICON

Description:...f blood vessels and is a useful marker for the identification of endothelial lineage in tumors. It is important to note that not all endothelial cells synthesize von Willebrand factor, therefore a small percentage of these vascular-rich tumors might not stain with this antibody. CD31 or platelet endothelial adh...
Company:CHEMICON
Synthesize in Biological Definition

Artificial life

...nical,theoretical and ethical challenges it has ever confronted. The time seems appropriate for a gathering of those involved in attempts simulate or synthesize aspects of living systems. Ed Fredkin founded the Information Mechanics Group at MIT , which united Toffoli, Norman Margolus , Gerard Vichniac ...

ATP synthase

... An ATP synthase ( EC 3.6.3.14) is a general term for an enzyme that can synthesize adenosine triphosphate (ATP) from adenosine diphosphate (ADP) and inorganic phosphate by utilizing some form of energy. The overall reaction seq...

Bacterium

...isms Bacteria show a wide variety of different metabolisms . Heterotrophs depend on an organic source of carbon, while autotrophs are able to synthesize organic compounds from carbon dioxide and water. Autotrophs that obtain energy by oxidizing chemical compounds are called chemotrophs , and those tha...

Cell metabolism

... 2.3 Protein catabolism 3 See also Anabolism Anabolism is a constructive metabolic process whereby energy is consumed to synthesize or combine simpler substances, such as amino acids , into more complex organic compounds, such as enzymes and nucleic acids . Catabolism ...

Chromosome walking

...nto several consecutive short ones. The basic technique is as follows: A primer that matches the beginning of the DNA to sequence is used to synthesize a short DNA strand complementary to the unknown sequence, starting with the primer (see PCR ). The new short DNA strand is sequenced using the ch...

Ion gradient

...me bacteriorhodopsin , here it is used for driving the molecular motor enzyme ATP synthase to make the necessary conformational changes required to synthesize ATP. Proton gradients are also be made by bacteria by running ATP synthase in reverse, this is used to drive flagellas. The F 1 F O ATP synthas...
Synthesize in Biological Dictionary

Transcriptase

... but the enzymes that are ... Moloney Murine Leukemia Virus (M-MuLV) Reverse Transcriptase is an RNA-directed DNA polymerase. This enzyme can synthesize a complementary DNA strand initiating from ... K P Jensen Research ... Link to free-energy consistent OPLS-AA force field for proteins ... We w...

Rolling circle

... Rolling circle replication describes a process of nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids. Some e...

RNA polymerase

...re essential to life and are found in... RNA polymerase II is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. A 550 kDa complex of 12 subunits, RNAP II is the most studied type of RNA polymerase . A wide range o...

Ribosomes

...ould be 70S particles (reminiscent of ... Explanation of how the information encoded in mRNA is translated into a polypeptide. ... Ribosomes that synthesize 13 of the proteins destined for the inner ... Ribosome , cell structure that uses genetic instructions transported in ribonucleic acid RNA t...

Reverse transcriptase

...troviruses need to reproduce. Moloney Murine Leukemia Virus (M-MuLV) Reverse Transcriptase is an RNA-directed DNA polymerase. This enzyme can synthesize a complementary DNA strand initiating from ... DNA/RNA Binding to Reverse Transcriptase . V. The Polypurine Tract. VI. Unzipping ... HIV-1 re...

Primase

...as both primase and helicase ... this study, we report the development of a primase -based ... which utilizes bacteriophage T7 gp4 primase to synthesize ... Primase ,biological,biology dictionary,biology terminology,biology terms,biology abbreviations ... of two proteins, a primase and a helicase...
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(Date:8/21/2014)... chronic kidney disease patients may be a strong indicator ... in the Journal of the American Society of ... Hopkins Bloomberg School of Public Health assert that coronary ... atherosclerosis in predicting the risk of heart disease among ... all patients with chronic kidney disease (CKD) die from ...
(Date:8/21/2014)... Texas MD Anderson Cancer Center today announced a new ... screening at a network of community breast care centers ... November, MD Anderson will become the exclusive provider of ... 10 breast care centers, located in Memorial City, The ... the network will expand to Memorial Hermann,s locations in ...
Breaking Medicine News(10 mins):Health News:Robin Williams: What he could not bear to face 2Health News:Robin Williams: What he could not bear to face 3Health News:Dental Insurance Now Quoted for Families Online at Insurer Portal 2Health News:Measuring calcium buildup to predict heart disease in those with chronic kidney disease 2Health News:MD Anderson and Memorial Hermann to operate breast screening network across Houston area 2
(Date:8/21/2014)... have developed a novel and versatile modeling strategy to ... new materials as well as for studying polyelectrolytes, including ... to model much larger and more complex polyelectrolyte systems, ... Li, lead author of a paper on the work ... Materials Science and Engineering. "This is a big step ...
(Date:8/20/2014)... a John and Rebecca Moores Professor of Biology and Biochemistry ... in the International Society for the Study of the Origin ... members two from the U.S., one from France and ... are elected every three years, and 36 have been named ... 20 countries, the ISSOL includes researchers from disciplines as varied ...
(Date:8/20/2014)... LAKE CITY Researchers at Huntsman Cancer Institute (HCI) at ... forms of the gene that encodes BCR-ABL, the unregulated ... According to the American Cancer Society, nearly 6,000 new ... Drugs already in use, called tyrosine kinase inhibitors (TKIs), ... They do not cure CML but control it in ...
Breaking Biology News(10 mins):Researchers develop models to study polyelectrolytes, including DNA and RNA 2UH professor named fellow by International Astrobiology Society 2Blueprint for next generation of chronic myeloid leukemia treatment 2
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