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Synapse in Medical News

Fujifilm Takes Virtualization Technology to Next Level

...y rolled out virtualized solutions across our full synapse informatics product portfolio, we're committed to ... Installed, configured and tested its synapse products at VMware's headquarters in Palo Alto. He...ies in both outpatient and hospital settings. The synapse brand of integrated products includes Synapse(TM) ...

ProSolv Version 4.0.2 Makes Commercial Debut at ASE

...tine image review, analysis and reporting with the synapse ProSolv cardiovascular application," explained Waitz. synapse ProSolv cardiovascular version 4.0.2 provides work...ll QLAB application directly from the image in the synapse ProSolv cardiovascular application for greater eff...

Recent developments at Burnham Institute for Medical Research, May 2009

... and subsequent synaptic damage and neuronal death in Alzheimer's disease. The good news is that this provides a new disease target that could prevent synapse loss and nerve cell death in Alzheimer's disease, constituting a new strategy for counteracting the disease. ...

Research Highlights Genetic Risk for Autism

...rise in rare instances when normal DNA variations disturb genes along a particular neural pathway, one linked to smooth nervous system development and synapse function. "By using state-of-the-art technology and large samples, we discovered new genes that appear to increase susceptibility to autism," said ...

ProSolv CardioVascular and GE Healthcare Ultrasound Division Announce Affiliation

...onsist of advanced reporting and image management software, comprehensive support services and integration with third-party clinical applications. The synapse ProSolv(R) cardiovascular Enterprise Image and Information Management solution improves physician productivity, enhances customer revenue opportunitie...

JumpStart and Case Technology Ventures Invest in Neuros Medical

...portfolio include AcelleRX Therapeutics , AnalizaDx , CardioInsight Technologies , CerviLenz , Freedom Meditech , Great Lakes Pharmaceuticals , synapse Biomedical , Tursiop Technologies , and VasoLux MicroSystems . * * * About Neuros Medical, Inc. Neuros Medical , a Cleveland, Ohio...

ProSolv Releases New Cardiovascular Software

...ation with the Siemens Sensis Hemodynamic system. synapse ProSolv cardiovascular 4.0.1 will be one of severa... for easier deployment across the enterprise. Now synapse ProSolv cardiovascular 4.0.1 takes that Web founda...namic system can now be imported directly into the synapse ProSolv cardiovascular database as well as into th...

Novel Photoconductive Cellular Depolarization Technology Reveals Insight Into Neuronal Growth, Guidance, and Regeneration

...poral resolution than direct neurotransmitter application. Previously, photoconductive stimulation has been applied to demonstrate activity-driven new synapse formation in cultured neurons while allowing for the dynamic observation of the cellular elements within the neurons. In the current study, the applic...

Fujifilm Sees Significant Growth of Managed Services Business

...cal Systems USA announced that it has expanded its synapse Managed Services capabilities to now include RIS h...ng is providing benefits for both existing and new synapse Managed Services customers. "With the addi... Tele-RIS services are another new addition to synapse Managed Services. Designed particularly with the n...

Fujifilm Acquires Information Systems Vendor Empiric

...solution. Fujifilm has already made substantial progress in integrating the synapse and Empiric applications, and with the acquisition we are now in a position...l 2007 acquisition and swift integration of ProSolv CardioVascular into the synapse portfolio. Fujifilm is the first major vendor to deliver seamless, Web-base...
Synapse in Medical Technology

Four Alzheimer's Clinical Trials Address a Variety of Treatment Targets - Amyloid, Tau, Synapse Formation

- Unsuccessful Phase III Study Does Not Mean the End of Anti-Amyloid Therapies - CHICAGO, July 29 /PRNewswire-USNewswire/ -- Results from four studies of potential new treatments for Alzheimer's - even an unsuccessful late stage clinical trial - increase the field's knowledge and point scien...

Clinical Data Published in 'Science' Show Tumor Regressions in Relapsed Lymphoma Patients Treated with T Cell Engaging BiTE Antibody Blinatumomab

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Synapse Biomedical Receives FDA Approval of NeuRx Diaphragm Pacing System (DPS)(TM) For Spinal Cord Injury Breathing Applications

... ALS Patients CLEVELAND, June 18 /PRNewswire/ -- synapse Biomedical Inc. (http://www.synapsebiomedical.com... on their own once again," said Anthony R. Ignani, synapse President and Chief Executive Officer. "The nation... Case Western Reserve University (a shareholder of synapse Biomedical) and the Veterans Administration (VA) M...

Micromet and MedImmune Commence Treatment in Phase 2 Trial of BiTE Antibody Blinatumomab (MT103/MEDI-538) in Patients with Acute Lymphoblastic Leukemia

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Micromet's BiTE Antibody Blinatumomab (MT103/MEDI-538) Demonstrates Durable Responses in Patients with Relapsed Non-Hodgkin's Lymphoma

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Micromet to Present Clinical Update for BiTE Antibody MT103/MEDI-538 at the International Conference on Malignant Lymphomas

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Micromet Enrolls First Patient in a Phase 1 Clinical Trial with MT110, the First BiTE Antibody for Treatment of Solid Tumors

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Micromet Shows Feasibility of Subcutaneous Delivery of BiTE Antibody in Preclinical Primate Study

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Micromet Presents Safety and Efficacy Data from Primate Studies With Two New BiTE Antibodies Developed for Treatment of Leukaemia and Melanoma

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...

Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies

...g, T cells against tumor cells, and represent a new therapeutic approach to cancer therapy. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks. These cytolytic synapses enable the delivery of ...
Synapse in Medical Dictionary

Synapse

Synapse India is a Software development company offering custom software ... Learn About Synapse ... Copyright 2009 Synapse Communications, All Rights Reserved. ... Synapse Group, Inc. | 225 High Ridge Road, East Building | Stamford, CT ... © Synapse Group, Inc. All Rights Reserved. T...

Vesicle

... The synaptic vesicle cycle. Synapses can fire at very rapid rates. ... Synaptic vesicle components are initially trafficked to the synapse using ... The mechanism of GLUT4 vesicle exocytosis in response to insulin is not understood. ... Vesicle binding to microtubules was not m...
Synapse in Biological News

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds

Cold Spring Harbor, NY -- A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny gaps across which the majority of neurons communi...

A key enzyme helps keep the synapse on track

NEW YORK (Dec. 20, 2007) -- At its core, healthy neurological function hinges on the efficient passage of information between brain cells via the synapse. Figuring out how the synapse traffics this information -- a process called neurotransmission -- is crucial to understanding the function of ...

Breakthrough technology observes synapse in real time, supporting theory of vesicular recycling

NEW YORK (Dec. 13, 2007) -- For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate. In doing so, they've also laid to rest a competing theory as to how key cellular processes ...

UC Davis researchers visualize formation of a new synapse

(SACRAMENTO, Calif.) A protein called neuroligin that is implicated in some forms of autism is critical to the construction of a working synapse, locking neurons together like "molecular Velcro," a study lead by a team of UC Davis researchers has found. Published online in the June issue of th...

Capturing the birth of a synapse

Researchers have identified the locking mechanism that allows some neurons to form synapses to pass along essential information. Mutations of genes that produce a critical cell-adhesion molecule involved in the work were previously linked to autism. The discovery -- captured with fluorescent im...

Laminin builds the neuromuscular synapse

Like a plug and a socket, a nerve and a muscle fiber mesh at the neuromuscular junction. New work by Nishimune et al published in the Journal of Cell Biology reveals that an extracellular matrix protein called laminin shapes both sides of the junction to ensure they fit together type="rel"doi="1...

The synapse is a shotgun

Researchers have constructed a new detailed map of the three-dimensional terrain of a synapse -- the junction between neurons which are critical for communication in the brain and nervous system. The "nano-map," which shows the tiny spines and valleys resolved at nanometer scale, or one-billionth o...

Building memories with actin

...l for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay do...cientists think that the process, in which a brain synapse becomes more potent after repeated stimulation, un...Rac-PAK pathway solidifies them so that heightened synapse sensitivity can persist. The researchers hypothesi...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...ost commonly used antidepressant drugs, the SSRIs, selectively inhibit the transport of the neurotransmitter serotonin, prolonging its activity in the synapse between the nerve cells. In the next step, the development of receptor subtype-specific drugs is currently encouraged. So-called hyperselective drugs ...

Scientists capture the first image of memories being made

...rlies long-term memory formation. The finding provides the first visual evidence that when a new memory is formed new proteins are made locally at the synapse - the connection between nerve cells - increasing the strength of the synaptic connection and reinforcing the memory. The study published in Science...
Synapse in Biological Technology

Medivation Presents New Data on Dimebon's Novel Mechanism of Action

...ndrial function has been correlated with increased synapse formation. Autopsy studies of brains from patient...ease. Preclinical Study Results As synapse formation is dependent on mitochondrial function a...mebon on neurite outgrowth, an important aspect of synapse formation. Results of the study showed tha...

Revealing the regulating mechanism behind signal transduction in the brain

...ed to the Center for Human Genetics (K.U.Leuven) are now discovering how the Fragile X protein (FMRP) ensures that protein production is controlled at synapse and regulated by brain activity. Their findings are being published in the authoritative scientific journal Cell . Fathoming the brain Our 'gr...

JumpStart Invests in Tursiop Technologies

...hcare companies in JumpStart's portfolio include AcelleRX Therapeutics, AnalizaDx, CardioInsight Technologies, CerviLenz, Great Lakes Pharmaceuticals, synapse Biomedical and Telerad Express. About Tursiop Technologies, LLC Tursiop Technologies is developing revolutionary MRI coil devices utilizing propri...

JCI table of contents: Dec. 3, 2007

...ring prolonged sleep loss. Communication between neurons occurs across synapses, the junctions between these cells. When the communication across a synapse is enhanced for a long time, it is called long-term potentiation. Following an imposed sleep deprivation (induced either by a drug or continual gentle...

Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling

..., that is useful for studying synaptogenesis and synapse elimination. Glutamate is a major excitatory n...inal; previously, it has been used as a marker for synapse formation and elimination. 8 Stratagen...ific marker that can be used to monitor synapse number and synaptogenesis. Again, Stratagene ...
Synapse in Biological Products

Rabbit Anti-SKAP55 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents

Description:...TCR signaling. SKAP55 has also been shown to enhance adhesion to fibronectin and ICAM1, colocalize with F-actin at the T cell-antigen-presenting cell synapse and promotes the clustering of LFA1 and TCR ligation. TCR engagement induces the translocation of SKAP55 to lipid rafts, where the interactions wit...
Company:ABR-Affinity BioReagents
Synapse in Biological Definition

Synapse

Synapses allow nerve cells to communicate with one another through axons and dendrites , converting electrical signals into chemical ones. Synapses are specialized junctions through which cells of the nervous system signal to one another and to non-neuronal cells such as mu...

Dendrite

.... In such dendrites the voltage change that results from stimulation at a synapse may extend both towards and away from the soma. In other dendrites, voltage...input from many others, particularly those that input only weakly (more at synapse ). This integration is in aspects "temporal" -- involving the summation of ...

Diffusion

... Quorum sensing Respiration Reverse osmosis Second messenger Semipermeable membrane SI derived unit Sintering synapse Transport phenomena External links Some pictures that display diffusion and osmosis ...

Long-term potentiation

..., 4446-51. References Deadwyler SA, Dunwiddie T, Lynch G. "A critical level of protein synthesis is required for long-term potentiation." synapse . 1987;1(1):90-5. PMID 3505366 Frey U, Morris RG. "Synaptic tagging and long-term potentiation." Nature . 1997 Feb 6;385(6616):533-6. PMID 9020...

Neuroscience

... top-down approach of psychology . The concern of neuroscience includes such diverse topics as the operation of neurotransmitters at the synapse ; the biological mechanisms that underlie learning (both declarative learning and motor learning ); how genes contribute to neural devel...

Signal transduction

...plasma membrane through which ions can pass. These ions will then relay the signal. An example for this mechanism is found in the receiving cell of a synapse . Signal transduction of transmembrane receptors on change of transmembrane potential An ion channel can also open when the receptor is ac...

Selective serotonin reuptake inhibitor

...e brain , information is passed between two neurons (nerve cells) via a synapse , a small gap between the cells. The neuron that sends the information rele...an effect on brain functions. Second, pure serotonin would turn on every synapse it reaches, whereas SSRIs only enhance a signal that is already present, ...
Synapse in Biological Dictionary

Synapse

For other uses, see Synapse (disambiguation) ... When the wave reaches a synapse , it provokes release of a puff of ... The word " synapse " comes from "synaptein" ... The Synapse SNAP ... Synapse Announces SNAP Availability on Panasonic's Long Range ... Future ...

Vesicle

...oteins ... The synaptic vesicle cycle. Synapses can fire at very rapid rates. ... Synaptic vesicle components are initially trafficked to the synapse using ... Definition of vesicle from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games...

Thalamus

...Neurobiology at Washington University Medical School! ... Our faculty study a variety of scientific questions ranging ... In the thalamus they synapse in the VPL (the ventroposterior lateral nucleus) ... They will enter the VPL of the thalamus together. ... Thalamus summary with 10 pages of...

Reflex arc

...r animals, most sensory neurons do not pass directly into the brain, but synapse in the spinal cord. This characteristic allows reflex actions to occur r... ... It is the simplest reflex arc and the integration center is the synapse itself. ... Reflex Arc . Organisation of the. Nervous System ... In ...

Membrane transporter

...s the neurotransmitter dopamine; DAT provides the primary mechanism through which dopamine is cleared from synapses, transporting dopamine from the synapse into... Disease Related Membrane Transporters . PharmTao Home ... region 1, candidate A; efflux transporter -like protein; imprinted multi- me...

Calyx

...ogether, these two structures are known as... Calyx (kidney), a structural component of the mammalian kidney ... Calyx of held, a large synapse in the auditory brainstem structure ... ... with surprises, and Calyx Flowers is where you ... Copyright 1997 - 2009 Calyx & Corolla, In...
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