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switched in Medical News

DNA Solves Switched at Birth Mystery ... After 57 Years

DNA solves another mystery when 57 year old Fred George discovered he was switched at birth. Fred's father, John George, occasionally - sometimes in fun and sometimes more seriously - accused his wife of having had an affair after Fred was born since he looked nothing like the rest of the family....

Drugs may Help Turn on Gene Switched Off in Cancer

Researchers from the University of Michigan Comprehensive Cancer Center suggest that drugs may be helpful in switching on a gene implicated in the development of cancer cells , raising hope for the development of a new class of targeted therapies with potential to benefit many different cancer type...

Silenced genes as a warning sign of blood cancer

..., parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This ...icularly the cancer inhibitors that are frequently switched off. The study of these questions is a very promis...n the genetic material, the DNA, genes can also be switched on or off by chemical labeling of the DNA or the D...

Pelosi, Democratic Leaders Remarks Today at News Conference on Legislative Accomplishments

...biggest opponent, of this legislation passing and with a public option in it. Because they know that the glory days are over of them. The leverage has switched to the consumer -- Congress and the President will remove the insurance industry from coming between the patient and his or her doctor. Q: ...

House Measure Proves Healthcare Legislation Will Fund Abortion, Says Family Research Council Action

...public or private plans passed in the committee, Chairman Henry Waxman (D-Calif.) called a re-vote on the amendment and Tennessee Democrat Bart Gordon switched his vote to the pro-abortion side. "Even those who claim abortion is not included cannot possibly deny that abortion is explicitly in the legi...

Does the Crowded TNF Market Really Need Two New Agents? Rheumatologists Provide Insight in the Wave One Report of LaunchTrends(TM): SIMPONI and CIMZIA

... More than one-half of surveyed physicians have prescribed Simponi while less than one-third report trial of Cimzia. Over 80% of Simponi patients were switched from other biologics (primarily Humira) while a higher percent of the Cimzia patients were biologic naive. The majority of Rheumatologists see both o...

Researchers Discover the Tale Behind Short Dogs

...als. The retrogene in the short-legged dogs produces too much of the FGF4 growth protein, which the team believes may cause growth receptors to be switched on at the wrong time during fetal development. This may be behind the known calcification of growth plates that prevents these breeds' legs from growi...

FDA Ruling on Mercury Fillings Falls Short

...uous attitude toward children and the unborn will not go unanswered. We will see FDA in court." Most consumers, and most dentists, have already switched to the main alternative, resin composite. The FDA rule destroys a dental myth that the mercury becomes inert in the mouth; FDA says the vapors from de...

Scientists Track Impact of DNA Damage in the Developing Brain

...he DNA damage response plays in preventing neurological disease," the investigators wrote. The study also marks the first time researchers have switched off a pathway for repairing damaged single DNA strands in an organ system, in this case the mouse brain and nervous system. While the results suggest ...

Medicare Drug Plan Still Needs Work

..., too, and has actually left some people worse off." He noted that low-income seniors who are "dually eligible" for both Medicare and Medicaid were switched from Medicaid drug coverage to Medicare Part D. In California, that shift resulted in seniors losing a relatively rich array of benefits. In general, ...
switched in Medical Technology

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

...der as the dosage of ASMANEX should be reduced slowly. If you or your child took steroids by mouth and are having them decreased or are being switched to ASMANEX, you should be followed closely by your health care provider and the oral steroids should be reduced slowly. Deaths due to adrenal insuffic...

ASMANEX(R) (Mometasone Furoate Dry Powder Inhaler) Now Approved in Japan for the Treatment of Bronchial Asthma in Adult Patients

...rovider as the dosage of ASMANEX should be reduced slowly. If you or your child took steroids by mouth and are having them decreased or are being switched to ASMANEX, you should be followed closely by your health care provider and the oral steroids should be reduced slowly. Deaths due to adrenal insuffic...

New Small and Medium Sized Enterprises Join TI Pharma by Signing Two New Projects

...formation are dependent on the formation of new blood vessels. Furthermore, angiogenesis is an early event in the development of tumors, being already switched on in pre-cancerous events and long before visible or clinically relevant tumor mass is present. Schaapveld: "These two features make angiogenesis an ...

AcelRx Announces Positive Phase 2 Results from a Study of ARX-01 Sufentanil NanoTabs in Treating Post-Operative Pain

...icted from oral medication. Patients appear to tolerate the Sufentanil NanoTabs well, and following the end of the 12-hour study period when they were switched to IV PCA morphine, many requested that they be returned to study drug. To me, these patients' requests are as demonstrative as any more quantitative ...

Infant Formula Company Teams With the University of Virginia Pediatrics Department to Conduct Clinical Studies

...en, M.D., Ph.D., U.Va. Department of Pediatrics and lead researcher on studies involving PBM formulas, it is very common for formula-fed infants to be switched from one formula to another during the first year of life. "It's important to remember that all infant formulas manufactured and sold in the Uni...

Two-Year Data Show Patients Receiving SIMPONI(TM) (golimumab) Experienced Sustained Improvement in Signs and Symptoms of Psoriatic Arthritis and Ankylosing Spondylitis

...y-three of 76 patients receiving SIMPONI 50 mg who switched to SIMPONI 100 mg in early escape also achieved AC...ty-five of 56 patients receiving SIMPONI 50 mg who switched to SIMPONI 100 mg in early escape also achieved PA..., patients with inadequate arthritis response were switched to SIMPONI 50 mg (patients originally receiving pl...

Arena Pharmaceuticals Announces Lorcaserin Data Demonstrating Highly Significant Categorical and Absolute Weight Loss and Improvements in Secondary Endpoints Associated with Cardiovascular Risk

...atients randomized to remain on lorcaserin for Year 2 maintained a significantly greater amount of weight loss compared to the lorcaserin patients who switched to placebo at Week 52 in both the ITT-LOCF and per protocol populations. Secondary Endpoint Analysis New data demonstrate that treatment w...

VIDEO from Medialink and the Epilepsy Foundation: New Study Suggests Different Versions of the Same Epilepsy Medication Can Be Harmful

...effects or sudden death when their medications are switched from one version of an antiepileptic drug (AED) to...seizures worsened for 59 percent of people who had switched from a brand-name to a generic AED, while side eff... seizures worsened for 15 percent of those who had switched from a generic to brand AED, while side effects in...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

...5 percent of patients who completed the study were switched successfully, meeting the primary endpoint. ...dpoint was the proportion of patients successfully switched (no worsening of UPDRS II+III >15 percent from ...the trial, of which 84.5 percent were successfully switched (with or without dose adaptation) to the once-dail...

Generic Substitutes Less Effective/Safe Than Branded Medications in Treating Lower Urinary Tract Symptoms

...taking branded alpha blockers or 5-ARIs with an average age of 64, who were switched to generic alternatives by their primary care physician or due to insurance...ry function and the prevalence of adverse events. In the men who were switched to generic medications, the IPSS and PVR rates increased and Qmax decreased...
switched in Medical Products

CLINI-RF Ultra Low Rapid Freezer Unit

Description:...entially hazardous substances such as carbon dioxide and liquid nitrogen. In order to save power, the compressor for the lower chamber can be manually switched off when it is not required and the Clini-RF will run in a 'standby' mode with the upper chamber still running at -40C. A seven day timing device i...
Company:myNeuroLab.com

Centricity® Physician Office - Practice Management (PM)

Description:...d structure, providing an easily adaptable solution as individual as your practice. Thousands of physician offices of every specialty and size - have switched from yesterday's Unix and DOS-based systems to the award-winning practice management system from GE. How can Centricity Physician Office - PM make a d...
Company:GE Healthcare

Khosla Vitrectomy Super (Gas Operated)

Description:... Variable cutting speeds (guillotine movements) are possible. Cutting port remains in open position when switched off, thus minimizing tissue trauma. One can select individual cutting or suction action, or both can be combined together. There are single or multi-p...
Company:Khosla Medical & Surgical, Inc.

Khosla Irrigation/Aspiration Vitrectomy Unit

Description:...ng speed-variable from 1- 600 cuts per minute. Independent or concurrent cutting, suction, reflux possible. Cutting port remains in open position when switched off, thus minimizing tissue trauma. Vacuum can be preset anywhere from 0-500mm Hg. Available in linear or fixed mode to match your individual needs. L...
Company:Khosla Medical & Surgical, Inc.

ANGIO CT MIYABI

Description:...emens SOMATOM CT scanner on rails (Sliding Gantry) and an AXIOM Multistar angiography unit. Both systems use the KOORDINAT M angio table, which can be switched between floating DSA position and fixed CT position. During angiography, CT is located in the park position. When it is nesessary to confirm t...
Company:Siemens Medical Solutions USA, Inc.

AXIOM CT Miyabi

Description:...emens SOMATOM CT scanner on rails (Sliding Gantry) and an AXIOM Multistar angiography unit. Both systems use the KOORDINAT M angio table, which can be switched between floating DSA position and fixed CT position....
Company:Siemens Medical Solutions USA, Inc.

High Voltage Non-Programmable Power Supplies

Features:...w for precise digital control while retaining the convenience of knobs. Once set, each adjustment control will retain its setting even if the power is switched off, eliminating the need to readjust the output when doing the same experiment repeatedly. Sophisticated safety features : Each Thermo power supply...
Company:ThermoFisher Scientific

ABBOTT PRISM

Features:...ses throughput by running up to 960 tests per hour with STAT test capability in under one hour for all available assays. Since 1996, countries have switched to ABBOTT PRISM for impressive safety, quality, productivity and reliability. There are over one hundred ABBOTT PRISM systems Test of Record internati...
Company:Abbott Diagnostics

Leica ASP200

Features:...esistant Intelligent user interface (protecting against programming and operation errors) Intelligent Reagent Management System RMS (can be switched ON/OFF) Efficient paraffin wax cleaning system 2-Phase fume control system: condenser to remove solvents from air inside the instrument plus...
Company:Leica Microsystems
switched in Medical Definition

Babies switched at birth

... Babies switched at birth are babies who, because of either erro...plot device The plot device of babies who are switched at birth, or in their cradles, has been a common o...Gondoliers . In both cases, well-born babies were switched with commoners. Mark Twain , later used this plot...
switched in Medical Dictionary

Lactase

...s. But in people who are lactose intolerant, that lactase gene is switched off after weaning. ... Mutations that keep the lactase gene permanently switched on are ... Lactase is the enzyme in the small intestine that dige...
switched in Biological News

GOCE's electric ion propulsion engine switched on

GOCE's sophisticated electric ion propulsion system has been switched on and confirmed to be operating normally, marking another crucial milestone in the satellite's post-launch commissioning phase. The success of GOCE's ultra-sensitive gravity measurements depends on finely controlling the sat...

U-M researchers discover gene switched off in cancer can be turned on

A gene implicated in the development of cancer cells can be switched on using drugs, report researchers from the University of Michigan Comprehensive Cancer Center. The finding could lead to a new class of targeted cancer therapies with potential to benefit many different cancer types. Popular n...

UC San Diego engineer provides insights to decades-old DNA squabble

...ading to cancer." The next step for Arya and his team is to study the mechanisms by which chromatin is regulated, and how those lead to genes being switched "on" and "off," genes being repaired in response to mutations, and genes being replicated during cell division. Arya believes that a molecular-level...

Scientists track impact of DNA damage in the developing brain

...le the DNA damage response plays in preventing neurological disease," the investigators wrote. The study also marks the first time researchers have switched off a pathway for repairing damaged single DNA strands in an organ system, in this case the mouse brain and nervous system. While the results suggest ...

Common allergy drug reduces obesity and diabetes in mice

...o four groups. The first was the control group; the second group was simply switched to a healthy diet; the third was given cromolyn or ketotifen fumarate; and the fourth was both given the drug and switched to a healthy diet. While symptoms of the second group improved moderate...

Female human embryos adjust the balance of X chromosomes before implantation

...lacenta continue to have the paternal X chromosome switched off, but it is switched back on in the cells that are going to form the in...ther the maternal or paternal X chromosome that is switched off," explained Ms van den Berg, who is a PhD stud...

Lack of happiness hormone serotonin in the brain causes impaired maternal behavior in mice

...ne in the brain. Tph2 produces the enzyme tryptophan hydroxylase (TPH), which is responsible for the formation of serotonin. After the researchers switched off Tph2, the animals produced almost no serotonin in the brain. Nevertheless, the animals were viable and half of them survived until adulthood. Howe...

The battle for CRTC2: How obesity increases the risk for diabetes

...author Yiguo Wang, Ph.D., mimicked the conditions of ER stress in mice, CRTC2 moved to the nucleus but failed to activate gluconeogenesis. Instead, it switched on genes important for combating stress and returning cells to health. On closer inspection, Wang found that in this scenario CRTC2 did not bind to CR...

Researchers observe single protein dimers wavering between two symmetrically opposed structures

...enaturing" chemical, which helps destabilize the protein structure. They found that as more of this chemical was added, the A2L2 proteins increasingly switched structure from mostly syn to significantly anti by twisting one of the protein copies in the dimer by 180 degrees. Additionally, by using a more compl...

CU-Boulder study shows 53 million-year-old high Arctic mammals wintered in darkness

...lesmere Island near Greenland on a summer diet of flowering plants, deciduous leaves and aquatic vegetation. But in winter's twilight they apparently switched over to foods like twigs, leaf litter, evergreen needles and fungi, said Eberle, curator of fossil vertebrates at the University of Colorado Museum of...
switched in Biological Technology

Ultrafast optical shutter is switched entirely by laser light

Its a rare case of all light and no heat: A new study reports that a laser can be used to switch a film of vanadium dioxide back and forth between reflective and transparent states without heating or cooling it. It is one of the first cases that scientists have found where light can directly prod...

New angle on gecko research

...and now an assistant professor of biological sciences at Clemson. "We show that perception of body orientation determines when the adhesive system is switched on." The scientists discovered that the tipping point which turns on the gecko's adhesive system is 10 degrees. Three of the six geckos studied app...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... brains, including death due to toxic overproduction of alpha-synuclein. Once the cyclic peptides were inserted into the model yeast cells, Kritzer switched the yeast into Parkinson's mode and waited to see which yeast cells survived. Of the approximately 5 million yeast cells that were inserted with a cyc...

Israeli scientists show bacteria can plan ahead

..., and found that, in addition to the genes that enable it to digest lactose, the gene network for utilizing maltose was partially activated. When they switched the order of the sugars, giving the bacteria maltose first, there was no corresponding activation of lactose genes, implying that bacteria have natura...

Keryx Biopharmaceuticals Reports Positive Phase 2 Study Results of Zerenex (Ferric Citrate) for the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients

...ny combination of these agents were eligible for enrollment and immediately switched to a starting dose of 4.5 grams per day of Zerenex (ferric citrate). In the...ny combination of these agents were eligible for enrollment and immediately switched to a starting dose of 6.0 grams per day of Zerenex (ferric citrate). Patie...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...utralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently discontinued and patients should not be switched to other erythropoietic proteins. The safety and efficacy of PROCRIT therapy have not been established in patients with a known history of ...

Raptiva Withdrawal Offers Upside for Enbrel and Humira According to Latest BioTrends Survey of U.S. Dermatologists

... expected to be discontinued from biologic therapy, it appears that Enbrel (Amgen/Wyeth) and Humira (Abbott) stand to gain the most for patients being switched to other agents. Roughly 20% of the respondents feel that the withdrawal of Raptiva will result in an overall decline in biologic use in their practi...

Schering-Plough Announces Changes to its Global Collaboration with Novartis to Develop Combination Therapies for Asthma and COPD

...rovider as the dosage of ASMANEX should be reduced slowly. If you or your child took steroids by mouth and are having them decreased or are being switched to ASMANEX, you should be followed closely by your health care provider and the oral steroids should be reduced slowly. Deaths due to adrenal insuffic...

Baseline Research Indicates High Interest in Centocor-Ortho Biotech's SIMPONI(R)

...s reported that close to 40% of their severe RA patients could be considered candidates for SIMPONI and that the majority of SIMPONI patients would be switched from other biologic agents. Market share projections suggest that SIMPONI will primarily draw from other TNF-inhibitors and 38% of the respondents sug...

ChartTrends(R): Bone and Mineral Metabolism in Dialysis Reveals Latest Trends in the Treatment of Calcium, Phosphorus and PTH

... and FMC's PhosLo. Within the sevelamer franchise, patient conversion to Renvela stands at about 27% and about half of the Renvela patients had been switched from Renagel. The vast majority of dialysis patients are on Active Vitamin D formulations such as Abbott's Zemplar and Genzyme's Hectorol. The u...
switched in Biological Products

NeuroCyte - Rat Neural Stem Cell Kit from Orion BioSolutions, Inc.

Description:...ok in culture, with an epithelial cluster below large radial glial-like cells with an extensive network of long branching processes. Once cultures are switched into the commitment base medium, growth factor withdrawal and retinoic acid induced differentiation proceeds (far right). With Neuro Cyte-NSC intrace...
Company:Orion BioSolutions, Inc.
switched in Biological Definition

Francis Crick

...logy for his other interest, consciousness . His autobiographical book What Mad Pursuit includes a description of why he left molecular biology and switched to neuroscience. Crick's book The Astonishing Hypothesis makes the argument that neuroscience now has the tools required to begin a scientific s...

Lyon hypothesis

... and Willard (2005) indicates that 15% of the genes on the inactive X chromosome are actually active across all women, and a further 10% of genes were switched on in some women. The hypothesis was first stated by Mary F. Lyon in 1961 while she was studying the genetic consequences of radiation expo...

Malaria

...or the immune system. By the time the human immune system learns to recognise the protein and starts making antibodies against it, the parasite has switched to another form of the protein, making it difficult for the immune system to keep up. The stickiness of the red blood cells is particularly pronounc...

Phosphorylation

...ylation Function In eukaryotes , protein phosphorylation is probably the most important regulatory event. Many enzymes and receptors are switched "on" or "off" by phosphorylation and dephosphorylation. Phosphorylation is catalyzed by various specific protein kinases , whereas phosphatases ...

Stem cell

... 3.2.1 Cancer 3.2.2 Spinal cord 3.2.2.1 Embryonic stem cells switched to neurons 3.2.2.2 Stem cell injection restores ability to walk ... reduce tumor mass by 80 percent. Spinal cord Embryonic stem cells switched to neurons In Jan. 2005, using stem cells science made major progress i...
switched in Biological Dictionary

Telomerase

...so ... Telomerase activation (TA-65)is a cutting-edge anti-aging supplement.Science has ... We all have the gene to make telomerase , but it's switched off. ... Telomerase -based Cancer Therapies: What are the advantages and disadvantages of promising new telomerase -based cancer therapies? ...

Proof-reading

... Since 100% of Proof - Reading .com's revenue comes via the Internet, it is absolutely ... recognition was at Proof - Reading .com, I immediately switched to VeriSign. ... ... writers feel uncomfortable about proof reading because they don't feel that ... Check the spelling by reading from the l...

Gene silencing

...quot; of a gene by a mechanism other than genetic modification. That is, a gene which would be expressed (turned on) under normal circumstances is switched off by machinery in the cell. RNA interference (RNAi) is a system within living cells that helps to control which genes are active and how acti...
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