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Research Reveals Anatomy of Suppressed Memories: Study

US researchers have identified the parts of the brain that are involved with suppressing unpleasant memories, a finding that could have implications for treating depression or post traumatic stress disorder, according to a study released Thursday. The concept of memory suppression has been...

Research into Suppressed Memories Could Help Treatment for Depression

US researchers have identified the parts of the brain that are involved with suppressing unpleasant memories, a finding that could have implications for treating depression or post traumatic stress disorder, according to a study released Thursday. The concept of memory suppression has been...

Bladder Pain Suppressed By Marijuana-Derived Drug

IP 751, a derivative of Marijuana has been found to suppress bladder pain associated with interstitial cystitis (IC) in animal models//. The synthetic drug is a analog of a metabolite of THC, the principal component of marijuana. The results of the new study presented at the annual meeting of the A...

Prostate tumour growth suppressed by flavonoids

Flavonoids have been regarded as nutritionally good compounds. Lot of research is being done in this direction.// Apigenin, a flavonoid found in herbs, fruits, and vegetables, slowed the growth of prostate cancer in mice, according to a new study. Previous studies already found flavonoids (fo...

Hagens Berman Sobol Shapiro: Vytorin and Zetia Makers Settle Class-Action Suit With Proposed $41.5 Million

...n settlement with drug manufacturers Merck & Co. (NYSE: MRK ) and Schering-Plough Corporation (NYSE: SGP ) to settle allegations the companies suppressed critical information about the efficacy and safety of prescription drugs Vytorin and Zetia. Merck and Schering-Plough previously settled similar clai...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

... levels were lowered by 64 percent two weeks after administration of FIRMAGON, 85 percent after one month, 95 percent after three months, and remained suppressed throughout the one year of treatment.(1,2) These PSA results should be interpreted with caution because of the heterogeneity of the patient populatio...

AMERIGROUP Reports Q2 Net Income of $49.6 Million or $0.94 per Diluted Share, Including $0.43 per Diluted Share Positive Impact from Tax Adjustment

...iming of premium receipts in several states. A decline in the medical claims payable liability and a reduction of variable compensation accruals also suppressed cash flow in the quarter. 2009 Outlook AMERIGROUP is updating its 2009 annual earnings guidance range to $2.90 to $3.05 per diluted share ...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

...l tumors increased in size. Administration of nanoparticles to three different ovarian cancer mouse models prolonged lifespan by nearly four weeks and suppressed tumor growth more effectively, and with minimal non-specific cytotoxicity, than in mice treated with clinically relevant doses of cisplatin and paclit...

Research Scientist Reports On Time-Tested Solution To Current Medical Crisis

... now known to cure without deadly side effects and 3) publicize the ancient suppressed methods of increasing the body's inner higher energies necessary for attain...t view as pagan and superstitious and consequently, the ancient models were suppressed and nearly lost in history. The Perfect Health Plan describes how the ...

Tips from the journals of the American Society for Microbiology

...and monitored anti-GRP antibody levels in vaccinated mice. Intramuscular injections induced high levels of specific antibodies against GRP as well as suppressed the growth of melanoma cells. Additionally, researchers intravenously injected cells in the lungs and found that cells were highly diminished indicat...
suppressed in Medical Technology

European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection

- Product Developed Through Joint Venture Between Bristol-Myers Squibb and Gilead Sciences, the First of Its Kind in HIV Treatment - PRINCETON, N.J. and FOSTER CITY, Calif., Dec. 17 /PRNewswire-FirstCall/ -- The European Commission has granted marketing authorization for ATRIPLA(R) (efavi...

Anthera's Varespladib Meets Primary Endpoint in Phase 2 FRANCIS Trial for the Treatment of Acute Coronary Syndrome

...cally significant reductions in total cholesterol and non-HDL cholesterol - Varespladib's immediate and selective inhibition of sPLA2 effectively suppressed inflammation following the index event and was further evidenced by a statistically significant reduction in C-reactive protein. - A statisticall...

Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy

...levels were lowered by 64 percent two weeks after administration of degarelix, 85 percent after one month, 95 percent after three months, and remained suppressed throughout the one year of treatment.(1)(2) These PSA results should be interpreted with caution because of the heterogeneity of the patient populati...

Studies Presented at AACR Annual Meeting Highlight Multiple Immunomodulatory Mechanisms of Peregrine's PS-Targeting Antibodies

...The new data we present confirms that PGN635 also triggers immune cells to produce other chemokines and cytokines that have the potential to alter the suppressed immune environment commonly found in tumors, attracting additional immune cells and stimulating more aggressive anti-tumor responses. We believe this...

Phase III Trial Showed Investigational Compound Arzoxifene Was Superior to Evista(R) (raloxifene HCl) in Increasing BMD in Postmenopausal Women with Osteoporosis

... "NEXT" Study Also Showed Arzoxifene Significantly suppressed Bone Turnover Markers versus Raloxifene in Postmen... Arzoxifene significantly suppressed bone turnover to a greater extent than raloxifene,...5 percent vs. -30.8 percent Arzoxifene suppressed bone turnover to a greater extent than raloxifene ...

New Hope to Beat Cancer

...system's killer cells, are extracted from the tumor and re-educated to attack the cancer cells. The patient's normal immune system is then temporarily suppressed using chemotherapy, and the newly trained T cells are returned to the patient. The T cells are expected to survive, replicate and kill the cancer. ...

Cequent to Present First Proof of Activity of an Oral RNAi Drug in Non-Human Primates at February Keystone Conference

...ained from the gastrointestinal mucosa indicate that oral tk RNAi treatment was effective in up to 84 percent of animals, and target gene levels were suppressed between 58 to 64 percent compared to control animals. Pharmacokinetic studies verified the presence of the engineered shRNA in the intestinal mucosa, ...

Stress-Related Disorders Affect Brain's Processing of Memory

...rain Imaging Center of McLean Hospital, Department of Psychiatry at Harvard Medical School in Boston. "Because traumatic memories are not adequately suppressed by the brain, they continue to interfere with the patient's life." Dr. Agarwal and colleagues used brain fMRI to explore alterations in the ne...

Parasites That Live Inside Cells Use Loophole to Thwart Immune System

...ne. Studies in macrophages in the culture dish and in mice demonstrated that these microbes did trigger arginase production and that this triggering suppressed nitric oxide production in macrophages. The researchers also traced the biochemical mechanism by which the organisms triggered arginase--finding that ...

First Published Study of New HPV Test for Developing Countries Shows High Accuracy in Predicting Cervical Disease

... It's estimated that 80 percent of women will get an HPV infection at some point in their lives. However, in most cases, the infection goes away or is suppressed by the body without causing problems. It is only infections that persist that can cause abnormal cells to form that may develop into cervical cancer i...
suppressed in Biological News

La Jolla Institute discovers novel tumor suppressor

...rative disease, he explained. The researchers also tested the finding by introducing an inactive form of STAT5 in PLC-beta 3 deficient mice. "This suppressed myeloproliferative disease in these mice," Dr. Kawakami continued. Dr. Kawakami said his research team got similar results in tests of human cell...

Study links virus to some cases of common skin cancer

... virus was first discovered in patients with Merkel cell carcinoma, a rare, aggressive skin cancer that occurs mainly in the elderly and people with a suppressed immune system. The people in the new study all had a healthy immune system. "Originally it was thought that this virus caused only this rare skin ca...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

...l tumors increased in size. Administration of nanoparticles to three different ovarian cancer mouse models prolonged lifespan by nearly four weeks and suppressed tumor growth more effectively, and with minimal non-specific cytotoxicity, than in mice treated with clinically relevant doses of cisplatin and paclit...

Maternal, paternal genes' tug-of-war may last well into childhood

...become less dependent on their mothers' sustenance. Conversely, babies with Beckwith-Wiedemann syndrome, in which some maternally derived genes are suppressed and paternal genes dominate, are born heavy with particularly large tongues. These individuals usually end up being tall, owing to their rapid growth ...

MicroRNAs help control HIV life cycle

...gion on the HIV virus. When either was altered, miR29s suppression of HIV replication and infectivity was reduced or eliminated. In addition, the team suppressed P-bodies in the cells and noted a similar effect. This suggests that HIV may use miRNAs to become dormant and escape immune response. ...

Tumor suppressor gene in flies may provide insights for human brain tumors

...sts predicted that PP2A would stop the tumor suppressor Polo and allow for unchecked cell growth. "We were very surprised when we found that PP2A also suppressed tumors," Wang said. Follow-up experiments showed that PP2A is important for regulating Polo kinase function, and showed that these two critical br...

Rutgers research tackles childhood epilepsy

...e brain that is most often the cause of childhood epilepsy. Introducing the drug rapamycin, originally used to prevent rejection in organ transplants, suppressed epileptic seizures in the mice. Epilepsy is the third most common neurological disorder in the United States after Alzheimer's disease and stroke. ...

Using 'dominance' to explain dog behavior is old hat

...hat his owner is leader of the pack is counter-productive; you won't get a better behaved dog, but you will either end up with a dog so fearful it has suppressed all its natural behaviours and will just do nothing, or one so aggressive it's dangerous to be around." ...

System that regulates blood pressure is amiss in some healthy, young blacks

...youth at risk of becoming hypertensive adults. "The way it's supposed to work is the higher your blood pressure goes, the system is supposed to be suppressed so you urinate out more sodium and the blood pressure goes down in response," says Dr. Matthew Diamond, nephrology fellow in the Medical College of Ge...

A longer lasting tumor blocker

... that blocking a different molecule, called M-CSF, suppressed tumor growth even after treatment was stopped. ... of bone tumor. Three weeks of anti-VEGF treatment suppressed tumor growth but, similar to other recent reports,... a similar regiment of an M-CSF inhibitor remained suppressed in the absence of drug. Another distinction bet...
suppressed in Biological Technology

InterMune to Present Abstracts on HCV Protease Inhibitor ITMN-191 and HCV Development Program at the EASL Meeting

... Incidence of Virologic Escape Observed During ITMN-191 Monotherapy is Genotype Dependent, Associated with a Specific NS3 Substitution, and suppressed Upon Combination with Peginterferon alfa-2a/Ribavirin . Additional InterMune Presentations at EASL Titles of additional InterM...

Mexican Department of Public Health to Launch Screening for Human Papillomavirus (HPV), Cause of Cervical Cancer

... social class." In the majority of women, the virus goes away or is suppressed by the body before it causes any problems. However, in others, the infectio...point in their lives. However, in most cases, the infection goes away or is suppressed by the body without causing problems. It is only infections that persist th...

InterMune Reports Third Quarter 2008 Financial Results and Business Highlights

...sset) in a 14-day replicon clearance assay and in a 3-week colony formation assay resulted in clearance of the HCV replicon and reduced or suppressed the emergence of drug-resistant viral variants. These results suggest that the combination would likely result in significantly greater an...

Oncolytics Biotech Inc. Collaborators to Present Preclinical Combination REOLYSIN(R) and Cisplatin Research at EORTC-NCI-AACR Annual Meeting

... that the combined therapy results in significantly increased cell death in vitro compared to either agent alone. In the mouse model, combined therapy suppressed tumour growth and significantly prolonged median survival time. The researchers concluded that the addition of chemotherapeutic agents can significant...

FDA Continues Review of Takeda's New Drug Application for Alogliptin (SYR-322), a DPP-4 Agent for Type 2 Diabetes

...is known that because GLP-1 suppresses glucagon secretion from the pancreas, the production of sugar in liver cells is also suppressed and appetite is suppressed as well. About Takeda Pharmaceutical Company Limited Located in Osaka, Japan, Takeda (TSE:4502) is a research-based global company with its main f...

InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting

...ombination of ITMN-191 with the active moeity of either R7128 or R1626 resulted in significantly enhanced clearance of the HCV replicon and reduced or suppressed the emergence of drug-resistant viral variants. This work was carried out in anticipation of future clinical studies using ITMN-191 with either R712...

JCI table of contents: April 22, 2008

..., whereas overexpression of Pin1 decreased the stability of the protein and suppressed tauopathy in mice engineered to express nonmutated human tau. By contrast, elimination of Pin1 in mice decreased the stability of P301L tau and suppressed tauopathy in mice engineered to express P301L tau, whereas overexpression o...

Avicena's HD-02 to Proceed to NIH Sponsored Phase III Huntington's Disease Trial

... published in the January 24, 2006 issue of Neurology and showed that HD-02 suppressed an oxidative damage marker, 8OH2DG, which is a measure of cellular injury. ... published in the January 24, 2006 issue of Neurology and showed that HD-02 suppressed a Huntington's disease marker. Some researchers have linked this oxidative ...

Survey Shows Most Women Can't Separate Fact From Fiction When It Comes to Cervical Cancer Prevention

...ry common virus, infecting approximately 80 percent of all women at some point in their lifetimes. In the majority of women, the virus goes away or is suppressed by the body before it causes any problems. A Pap smear can identify cells that have become abnormal due to HPV, while HPV testing detects the presence...

In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement:

...8 /PRNewswire-FirstCall/ -- Eli Lilly and Company strongly objects to implications in a New York Times article published Thursday that the company has suppressed results of negative clinical trials. The story, based on a separate article in The New England Journal of Medicine (NEJM), cited Prozac and Lilly as...
suppressed in Biological Definition

Active site

...and chemical properties of the active site allow the recognition and binding of the substrate . The active site in many enzymes can be inhibited or suppressed by the presence of another molecule. There are three primary modes of inhibition. In competitive inhibition , the active site itself is blocked when ...

Antibody

...ds of time to avoid them. This is the reason for the chronic nature of many minor skin diseases (such as cold sores ); any given outbreak is quickly suppressed by the immune system, but the infection is never truly eradicated because some cells retain viruses that will resume it later. Medical applicatio...

Apoptosis

...and functional elements of the cell, resulting in the previously described morphological changes. Biochemical execution Caspases are normally suppressed by IAP (inhibitor of apoptosis) proteins [8] . When a cell receives an apoptotic stimulus, IAP activity is relieved after SMAC (Second Mitochondria-...

Cancer

...involve oncogenes or tumor suppressor genes. In general, mutations in both types of genes are necessary, as a mutation limited to an oncogene would be suppressed by normal mitosis control. Mutations can have various causes. Particular causes have been linked to specific types of cancer. Tobacco smoking is ...
suppressed in Biological Dictionary

Spermatids

...permatids . ... The release of mature elongated spermatids from the testis (spermiation) is also ... Early round spermatids in stages I-VII are suppressed to 20% of normal, yet ... Rodent spermatocytes, round and elongated spermatids (14–16), and Sertoli (13) ... ( 14) appeared to demonstrate that ...

Memory cell

...memory will give you a body sensation such as pain or ... The problem with suppressed cellular memory is not only does it limit our ... Information about ...itecture for multi-function cell phones typically ... The problem with suppressed cellular memory is not only does is limit our ... Supporting the cleari...

Coding region

...The protein coding regions represent an essentially different environment to the ... Accordingly, repeats in coding regions are strongly suppressed and it is hard to ... ... it predicts the most probable coding region based on the intrinsic signals of ... The protein- coding region exten...
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(Date:4/18/2014)... one of your worst memories? How did it make ... during a negative personal experience, such as how sad ... to emotional distress, especially when you can,t stop thinking ... up, thinking about the context of the memories, rather ... effective way to alleviate the negative effects of these ...
(Date:4/18/2014)... lead to potential new treatments for breaking the cycle ... Fibrosis, or scarring, is a hallmark of the disease, ... lead to serious organ damage and, in some cases, ... on findings made by Swati Bhattacharyya, PhD, research assistant ... specific protein plays in promoting fibrosis. , "Our ...
(Date:4/17/2014)... of the most popular vaccine brands for children may ... be overlooking some cost factors when choosing vaccines, driving ... option, according to a new study by University of ... can be driven by numerous factors," says Sheldon H. ... of computer science and of mathematics at the U. ...
(Date:4/17/2014)... published in the April issue of Immunity , ... for Medical Research, says it,s time to take a ... treating sepsis, which kills millions worldwide every year, ... molecules released into the bloodstream to fight an injury ... necessary for maintaining good health without inflammation, wounds ...
(Date:4/17/2014)... as many as 10 million older Americans suffer from ... isolation. , However, new research a project that ... for six years found that Internet use among ... more than 30 percent. , "That,s a very strong ... of telecommunication, information studies and media who led the ...
Breaking Medicine News(10 mins):Health News:New study suggests a better way to deal with bad memories 2Health News:New study suggests a better way to deal with bad memories 3Health News:New clues on tissue scarring in scleroderma 2Health News:Study recalculates costs of combination vaccines 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Internet use can help ward off depression among elderly 2
(Date:4/20/2014)... a newborn baby a gift of germsgerms that ... antibiotics, used to fend off infection, may paradoxically ... premature babies more susceptible to dangerous pathogens. ... at The Children,s Hospital of Philadelphia (CHOP) sheds ... gut microbes play a crucial role in fostering ...
(Date:4/18/2014)... world population predicted to reach 9 billion by ... that considers human-altered landscapes such as farmland, according ... habitat that supports it might be an increasingly ... three-quarters of the land surface is directly affected ... human-caused impacts such as climate change. But what ...
(Date:4/18/2014)... led by a University of California, Riverside professor of ... Department of Defense grant to uncover fundamental design rules ... predictable design of light-weight, tough and strong advanced materials ... and animals, including the mantis shrimp, toucan and bamboo. ... over millions of years and coming up with design ...
Breaking Biology News(10 mins):Study of gut microbes, antibiotics: Clues to improving immunity in premature infants 2Stanford researchers rethink 'natural' habitat for wildlife 2Stanford researchers rethink 'natural' habitat for wildlife 3Stanford researchers rethink 'natural' habitat for wildlife 4Mantis shrimp, toucan and trilobite, oh my 2Mantis shrimp, toucan and trilobite, oh my 3
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