suppress

Scientists identify molecule that regulates well-known tumor suppressor

Scientists have discovered that a molecule called DJ-1 is likely to be involved in the generation of human tumors through negative regulation of the well-known tumor suppressor, PTEN. The research, published in the March issue of Cancer Cell, has important implications for determining the prognosis of some human cancers, and may prove to be a suitable target for cancer therapy. The phospha...

First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes

Biologists at the University of Liverpool have discovered how the plagues of the Middle Ages have made around 10% of Europeans resistant to HIV. Scientists have known for some time that these individuals carry a genetic mutation (known as CCR5-delta32) that prevents the virus from entering the cells of the immune system but have been unable to account for the high levels of the gene in Scandinavi...

New tumor-suppressor gene discovered

A new tumor-suppressor gene has been discovered by a team of researchers at Penn State, which also has discovered how the gene works with another tumor suppressor to control tissue growth. The team's genetic and biochemical studies will be published in the 11 March 2005 issue of the journal Cell. "This discovery extends our understanding of how tissue growth is controlled both during normal devel...

Bee mites suppress bee immunity, open door for viruses and bacteria

A non-native bee mite is causing the dramatic and sudden collapse of bee colonies across the country, but Penn State researchers believe they have found the combination of factors that triggers colony deaths which includes suppression of the bee immune system by the mites. The Varroa destructor mite is a honey bee parasite that feeds much like a tick on the body of a bee. The mites are ab...

Natural tumor suppressor in body discovered by UCSD medical researchers

A natural tumor suppressor that could potentially be turned on in certain cancer cells to prevent the formation of tumors has been discovered by researchers at the University of California, San Diego (UCSD) School of Medicine. Located on chromosome 18 and called PH domain Leucine-rich repeat Protein Phosphatase (PHLPP, pronounced "flip"), the tumor suppressor is described in the April 1,...

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Mouse Anti-LATS, large tumor suppressor, homolog 2 (Drosophila) Monoclonal Antibody, Unconjugated, Clone 3D10 from Novus Biologicals

Description:Mouse monoclonal antibody to Lats2....
Company:Novus Biologicals

Rat Anti-Kinase Suppressor Of Ras Monoclonal Antibody, Unconjugated, Clone MINT/1/4 from GeneTex

Description:Rat Antibody to Kinase Suppressor Of Ras human kinase supressor of Ras...
Company:GeneTex

Tumor Suppressor Sampler Kit from BD Biosciences Pharmingen

Description:Tumor Suppressor Sampler Kit 10 mu g each...
Company:BD Biosciences Pharmingen

suppress at Biology Technology

A new LC/MS/MS Research Method for Rapid Quantitation of Five Immunosuppressant Drugs, including Mycophenolic Acid (MPA)

A previously published application note in this series describes an LC/MS/MS method for the simultaneous determination of four immunosuppressant drugs: Cyclosporin A (CsA), Tacrolimus (TAC, aka FK-506), Sirolimus (SIR, aka Rapamycin) and Everolimus (EVE, aka RAD-001) (1, 2). The method is based on a simple and robust hardware configuration and...

A Screen of shRNAs Targeting Tumor Suppressor Genes to Identify Factors Involved in Paclitaxel Sensitivity

Diana Ji, Stacy L. Deeds, and Edward J. Weinstein RNA interference methodologies have been utilized in small to large scale screening projects. The technology has allowed researchers to perform gene-silencing experiments in timeframes and target cells previously not possible. While siRNA screens have become fairly common, large scale screening wi...

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Tumor Suppressor p53's Contradictory Regulatory System

A new study appearing in the online open-access journal PLoS Biology examines the role played by the tumor suppressor protein called p53. It has been found that any mutations of p53 play a key role in the development of many human cancers. //This particular study was carried out by Min Hu, Yigong Shi and colleagues. To provide a bit of background, when there a cell injury, p53 triggers...

Vitamins suppress artery injury after transplant

According to a new study, Vitamin C and E supplements protect the coronary arteries from narrowing after heart transplant. Heart transplantation can be a life-saver// but, the vessels linking the new heart let the patient down by becoming blocked. If only a way could be found of blocking this process known clinically as arteriosclerosis. Now doctors at The Hopkins Hospital in Boston, US,...

Measles Suppresses AIDS Virus

HIV-positive children ill with measles may get a temporary respite from the virus that causes AIDS. Levels of HIV are suppressed while measles infection rages, the team found. "We were surprised by these findings, because we expected to see HIV replication increase, not decrease with measles//," Dr. William Moss, who led the study, said. He said measles usually suppresses the immune syste...

Suppressing A Girls Height In Adolescence Could Lead to Fertility Problems

Latest research shows that giving adolescent girls estrogen treatments to keep them from getting too tall could leads to fertility // problems later on in life . Estrogen is thought to limit height by altering long bone development. The study involved 780 women who had been assessed for estrogen therapy as girls and completed a fertility survey later in life. About half had actually been...

Acid Suppressive Drugs Found To Increase The Risk for Pneumonia

A recent study shows that people who use stomach-acid suppressive medications for indigestion or gastroesophageal reflux disease (GERD) may be at an increased risk of developing pneumonia .// The use of acid-suppressive drugs for the stomach can increase vulnerability to infections, as stomach acidity is a major defense mechanism for ingested pathogens. Researchers studied pneumonia ra...

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Lyphochek Elevated Immunosuppressant Control

Description:Lyphochek Elevated Immunosuppressant Control is a bilevel Cyclosporine control product, prepared from human whole blood. This unique product is ideal for use with assay methods that monitor very high Cyclosporine levels, such as C2 monitoring, which measures Cyclosporine levels in transplant patients at two hours post-dose. Lyphochek Elevated Immunosuppressant Control can also be used wit...
Company:Bio-Rad Laboratories

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Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression

Findings Published in Molecular Cell Show Potential of microRNAs asNovel Cancer Drug Targets REHOVOT, Israel and NORTH BRUNSWICK, New Jersey, July 05, 2007/PRNewswire-FirstCall/ -- Rosetta Genomics Ltd , a leading microRNAcompany, announced today research published in the journalMolecular Cell by scientists from the Weizmann Institute of Scienceand Rosetta Genomics . The findings suggest...

Argos Therapeutics Presents Immunosuppression Data for Soluble CD83 at the American Society of Transplantation Congress 2007

DURHAM, N.C.--(BUSINESS WIRE)--May 4, 2007 - Argos Therapeuticstoday announced the presentation of data on the immunosuppressiveproperties of soluble CD83 at the 7th Joint American Transplantmeeting to be held in San Francisco, May 5-9. The presentationswill be made in collaboration with scientists at the University ofWestern Ontario. "These data suggest that soluble CD83 is able to exten...

Data Show SuperGen's Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51

Other Presentations at AACR Highlight Progress in SuperGen'sOncology-Focused Pre-Clinical Pipeline LOS ANGELES, April 19, 2007 /PRNewswire-FirstCall/ -- SuperGenInc. today announced that MP470, its multi-targeted tyrosine kinaseinhibitor, suppresses the Rad51 protein, a critical component ofdouble- stranded DNA repair in cancer cells as part of a series ofpresentations at the 2007 America...

Immunosuppressant Drug Prevents Tobacco Induced Lung Cancer in Mice

BETHESDA, Md., April 1, 2007--Rapamycin, an FDA-approved drugnormally used to help prevent the body from rejecting organ andbone marrow transplants and also used to coat cardiac stents, washighly effective in preventing the development of tobacco-relatedlung tumors in mice. In a study published in the April 1, 2007issue of Clinical Cancer Research, researchers at the NationalCancer Insti...

Study in Cell by Magen BioSciences Co-Founder David E. Fisher Identifies New Roles in Skin Cancer Prevention for Key Tumor Suppressor Protein

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Mar 8, 2007 - Magen BioSciences,Inc., a specialty dermatology company, today announced thepublication of a paper in the March 9, 2007 issue of the journalCell by its co-founder and board member, David E. Fisher, M.D.,Ph.D., that identifies two new functions for an important protein,p53, in the pigmentation of skin. Fisher's study shows that inaddition to i...

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Depolarization-induced suppression of inhibition

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Immunosuppressant drugs

such as prednisone and methylprednisone; the <a href="/ ?q=/ Medicine-Dictionary/ h...