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New, automated tool successfully classifies and relates proteins in unprecedented way

For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a cell.The approach, developed by Carnegie Mellon University, outperformsexisting visual methods to localize proteins inside cells...

Biomarkers isolated from saliva successfully predict oral and breast cancer

Screening for breast cancer and the early detection of other tumors one day may be as simple as spitting into a collection tube or cup, according to recent studies by UCLA researchers. In one early study based on a risk model, presented here at the 96th Annual Meeting of the American Association for Cancer Research, the UCLA scientists reported that genetic "biomarkers" isolated in saliva...

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

A team of scientists led by biophysicist Stuart Lindsay from the Biodesign Institute at Arizona State University has created the first reproducible single molecule negative differential resistor ?and in the process has developed a groundbreaking experimental technique that provides a “roadmap?for designing single-molecule devices based on biochemistry. The findings were presented Feb. 18...

UN successfully tests 'green' pesticide against locusts

A new method for manipulating macromolecules has been developed by researchers at the University of Illinois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules. In previous DNA nanotechnology efforts, duplex DNA has been used as a static lattice to construct geometrical objects in three dimensions. Instead of manipulating DNA alone into s...

Stem cell therapy successfully treats heart attack in animals

Final results of a study conducted at Johns Hopkins show that stem cell therapy can be used effectively to treat heart attacks, or myocardial infarction, in pigs. In just two months, stem cells harvested from another pig's bone marrow and injected into the animal's damaged heart restored heart function and repaired damaged heart muscle by 50 percent to 75 percent. The Hopkins findings, fir...

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Keys to Successful Densitometry

Stratagene Cloning Systems Eagle Eyes Still Video System shown with Darkroom Cabinet Stratagenes new Eagle Sight software version 3.0 allows researchers to determine integr...

Critical factors for successful microarray and real-time PCR analyses

QIAGEN GmbH, Hilden, Germany Gene expression profiling at the RNA level has been significantly facilitated by microarray analysis and quantitative real-time RT-PCR. Microarray analysis offers the advantage of profiling expression levels of hundreds or thousands...

Successful PCR amplification and subcloning of a GC-rich DNA fragment

Petra Majlingov, Paolo Paroncini, Silvia Svegliati, Michele Luchetti, and Armando Gabrielli Laboratorio di Medicina Molecolare, Istituto di Clinica Medica, Polo Didattico Scientifico, Ancona, Italy The formation of robust secondary structures that resist denaturation makes GC-rich sequ...

General Considerations for Successful Transfection Experiments

Keep an eye on your cells; ensure they are in good condition and set a suitable plating protocol for optimal cell density from the beginning to the end of transfection....

Designing a Successful qRT-PCR Experiment

A Successful One Step qRT-PCR Experiment Requires Careful Consideration of Several Important Factors: To determine if your gene of interest is represented in an RNA sample, end point PCR followed by gel based staining is suitable. For target q...

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Endangered species may be successfully cloned in another animal's womb

Scientists for the first time have found a way for the survival of endangered animal species of the world. In a major breakthrough a Massachusetts scientists who engineered the feat has managed to clone cells from an endangered animal (Asian Gaur) and successfully impregnated an Iowa cow with the clone. The scientific journal Cloning has reported in its upcoming edition that...

Indian Prime Minister has successful Knee Replacement Surgery

Mr. Atal Behari Vajpayee, the Prime Minister of India has successfully undergone left knee joint replacement by Dr. Chittaranjan Ranawat at the Breach Candy Hospital in Mumbai. "The operation, which started at around 10 a.m., was completed by 11.15 a.m. and went on very well, to my satisfaction," Dr. Ranawat said at a press briefing. ``He (Mr. Vajpayee) was awake and comfortable throughout the op...

Plastic Sling Has Proved Successful In Improving Aging Of The Neck

A new idea in plastic surgery is proving successful at reducing the signs of aging in the neck. The procedure involves implanting a thin,// plastic sling under the skin and jaw to reduce the saggy appearance of the neck. Researchers say this new procedure is safe and very effective. As people age, there are often changes in the neck and face including the loss of elasticity in the skin...

Hope for Marburg treatment: vaccine successful in primates

The deadly Marburg virus that had affected a total of 423 cases in Angola,// which had left 357 dead, may finally have a treatment in the form of a vaccine. A virus causes Marburg hemorrhagic fever from the same family of virus that cause Ebola hemorrhagic fever. The disease is a rare condition but have the potential of causing an outbreak very fast. The symptoms begin with severe head...

Successful creation of human embryos from a single parent for the first time

Parthenogenesis refers to reproduction by the development of an unfertilized egg or development of eggs from females without fertilization by spermatozoa. Sounds interesting right? Hang// On! This is not all. Scientists have been successful in creating so-called parthenotes, early-stage embryos that are made from a single egg, without the need for sperm. The researchers have so far create...

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Siemens Webcast: Expert Insight - Key Elements for a Successful Electrophysiology Program

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Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension

Next Generation Renin Inhibitor to Continue Phase II Profilingin Diabetic Patients BASEL/Switzerland and BRIDGEWATER NJ/USA, 28 June 2007-Speedel(SWX: SPPN) today announced that it has reached another significantmilestone in the development of its family of renin inhibitors withthe successful completion of a Phase IIa proof-of-concept clinicaltrial with SPP635 for the treat...

Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology

FREISING-WEIHENSTEPHAN, Germany, June 21, 2007 /PRNewswire/ --Pieris AG, a bio-pharmaceutical company developing Anticalins(R), anovel class of targeted human protein therapeutics, announced todaythat its proprietary Duocalin(R) technology has successfullydemonstrated dual targeting potential. Commenting on this development, Dr Andreas Hohlbaum, Director ofScience and Preclinical D...

Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin

VIENNA, Va., June 20, 2007 /PRNewswire/ -- Modigene Inc., aNevada corporation today announced the successful completion ofpharmacokinetic and pharmacodynamic pre-clinical experiments forlong-acting human growth hormone, long-acting interferon beta andlong-acting erythropoietin. Modigene's pharmacodynamic and pharmacokinetic pre-clinicalexperiments demonstrated superb durability of...

Second Successful Quigley QR-443 Study Suggests Method of Action Relevant to Broad Range of Chronic Inflammatory Diseases - Human Study to Follow -

DOYLESTOWN, Pa., June 20, 2007 /PRNewswire-FirstCall/ -- QuigleyPharma, <a target="_blank" href="http://www.quigleypharma.com/">www.QuigleyPharma.com , a whollyowned subsidiary of The Quigley Corporation announced today that ithas completed a follow-up study to evaluate the impact of QR-443 onlevels of a pro-inflammatory cytokine Interleukin-6 (IL-6) in acachexia model. This new data...

Javelin Pharmaceuticals Announces Successful Pivotal Phase 3 Trial Data

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jun 19, 2007 - JavelinPharmaceuticals (AMEX: JAV) announced today that its productcandidate Rylomine(TM) (intranasal morphine) successfully met itsprimary clinical endpoint, the Sum of the Pain Intensity Difference(SPID) scores over 0-24 hours postoperatively. In this first of twopivotal Phase 3 studies, patients with moderate-to-severe painafter elective...

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