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Substrate in Medical News

Tamiflu substrate produced from Bioengineered Bacteria

The worldwide scare of bird flu pandemic as increased which has lead to stockpiling of large quantities of Tamiflu, antiviral bird flu drug by many countries//. U.S. has stocked more than 4 million Tamiflu drugs and many countries have started producing the generic version of the drug Tamiflu manuf...

Smith & Nephew Announces Launch of ACTICOAT Flex Wound Care Products in the USA

... "The Flex dressing allows exudate to pass through, which is a great advantage," he explained. "Combining the flexibility of the polyester mesh substrate with the proven effectiveness of ACTICOAT's nanocrystalline silver technology is an exciting and significant development for the ACTICOAT brand. The ...

Immunoassay at AACC 2009: Tosoh Launches AIA-2000 Automated Immunoassay Analyzer

...refrigeration, no pre-mixing, and no pre-measuring. AIA-2000 system features include: throughput of 200 tests/hour, 576 tips (6 tip racks), 2 substrate bottles, walk away time of 4 hours, 3 incubators with different processing steps, 2 sampling arms for faster processing of second reagent, and a full ...

Making nanoparticles in artificial cells

... from the production chamber. Instead, the bubbles remain attached to their substrate via small membrane channels, like balloons tied to strings, and stand in a ... vesicles at first. The second ingredient only creeps gradually between the substrate and membrane into the channel and to the vesicle. In the vesicle, where the...

Derma Sciences Announces First Commercial Sales of BIOGUARD(TM) Barrier Dressings

...ivity even in the presence of wound fluid and blood, and also in that the active component is non-leaching. Leaching antimicrobials can exit the base substrate dressing and potentially lead to interference in wound healing as well as to the creation of resistant strains of pathogens. Currently, the market fo...

ThermoGenesis Appoints Chief Executive Officer J. Melville ('Mel') Engle to Board of Directors

...irectors of Oxygen Biotherapeutics (OXBO), a company developing pharmaceuticals and medical devices in the field of oxygen therapeutics and continuous substrate monitoring. Engle holds a B.S. in Accounting from the University of Colorado and an M.B.A. in Finance from the University of Southern Californ...
Substrate in Medical Technology

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

...oint of the change in the amount of kidney interstitial capillary GL-3, the substrate that accumulates in the cells of Fabry patients. In addition, the FDA is i...ed in white blood cells and in the kidney, and reduced levels of the target substrate (GL-3), as measured in renal interstitial capillary cells from kidney biops...

Oxygen Biotherapeutics, Inc. Receives Letter From FDA Outlining Path Forward to Resume Oxycyte Clinical Trials in TBI in U.S.A.

...iotherapeutics, Inc. is dedicated to commercializing innovative pharmaceuticals and medical devices in the field of oxygen therapeutics and continuous substrate monitoring. The company has under development a perfluorocarbon therapeutic oxygen carrier and liquid ventilation product (Oxycyte(R)) and an implanta...

Amicus Therapeutics Announces Positive Progress of Three Lead Clinical Programs and General Outlook for 2009

...it supports a Phase 3 clinical trial comparing Amigal to placebo based on a surrogate primary endpoint of the change in the amount of kidney GL-3, the substrate that accumulates in the cells of Fabry patients. Amicus plans to continue discussions with the FDA through a Special Protocol Assessment (SPA) procedu...

Video: Tasigna(R) Demonstrates Rapid Response as Initial Therapy in Life-Threatening Form of Leukemia

... if possible. Tasigna inhibits human P-glycoprotein. If Tasigna is administered with drugs that are substrates of Pgp, increased concentrations of the substrate are likely and caution should be exercised. Tasigna may also induce CYP2B6, CYP2C8, and CYP2C9. Therefore, Tasigna may alter serum concentration of ot...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

... if possible. Tasigna inhibits human P-glycoprotein. If Tasigna is administered with drugs that are substrates of Pgp, increased concentrations of the substrate are likely and caution should be exercised. Tasigna may also induce CYP2B6, CYP2C8 and CYP2C9. Therefore, Tasigna may alter serum concentration of oth...

SuperGen's PIM Kinase Inhibitor, SGI-1776, Causes Tumor Regression in AML Xenograft Models

...induces cell cycle arrest, dose dependent apoptosis and a reduction in phospho-BAD levels in leukemia and lymphoma cell lines. Phospho-BAD is a direct substrate for PIM, and may serve as a useful in vivo biomarker for future clinical trials. Most notably, SGI-1776 induced significant tumor regression in MOLM-1...
Substrate in Medical Products

Anti-Thyroid Antibody (TA) Test Kit - Monkey Thyroid Substrate

Description: Inverness Medical Professional Diagnostics is a leading provider of immunofluorescence assays, with an extensive IFA and DFA test menu that includes kits for autoimmune diseases, infectious diseases and STDs as well as miscellaneous conjugates and components. Our Impact IFA Test Systems give you a ...
Company:Inverness Medical Innovations

Autoantibody Screen (AAS) Test Kit - Rat Kidney/Stomach Substrate

Description: Inverness Medical Professional Diagnostics is a leading provider of immunofluorescence assays, with an extensive IFA and DFA test menu that includes kits for autoimmune diseases, infectious diseases and STDs as well as miscellaneous conjugates and components. Our Impact IFA Test Systems give you a ...
Company:Inverness Medical Innovations

Anti-Nuclear Antibodies (ANA) Hep-2 Substrate

Description: Inverness Medical Professional Diagnostics is a leading provider of immunofluorescence assays, with an extensive IFA and DFA test menu that includes kits for autoimmune diseases, infectious diseases and STDs as well as miscellaneous conjugates and components. Our Impact IFA Test Systems give you a ...
Company:Inverness Medical Innovations

Anti-Smooth Muscle Antibody (ASMA) Test Kit

Description:...s conjugates and components. Our Impact IFA Test Systems give you a wide assortment of substrates and kit sizes to choose from. Kit components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence assoc...
Company:Inverness Medical Innovations

Anti-Mitochondrial Antibody (AMA) Test Kit

Description:...s conjugates and components. Our Impact IFA Test Systems give you a wide assortment of substrates and kit sizes to choose from. Kit components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence assoc...
Company:Inverness Medical Innovations

Anti-Native Deoxyribonucleic Acid (nDNA) Test Kit

Description:...s conjugates and components. Our Impact IFA Test Systems give you a wide assortment of substrates and kit sizes to choose from. Kit components include substrate slides, controls, conjugate, mounting medium, phosphate-buffered saline (PBS) and ZORBA-NS serum diluents to reduce the nonspecific fluorescence assoc...
Company:Inverness Medical Innovations
Substrate in Biological News

Silicon with afterburners: Process developed at Rice could be boon to electronics manufacturer

... law cannot be sustained indefinitely. The challenge is to get past the limits of doping, a process that has been essential to creating the silicon substrate that is at the heart of all modern integrated circuits, said James Tour, Rice's Chao Professor of Chemistry and professor of mechanical engineering an...

2000-year-old statue of an athlete sheds light on corrosion and other modern challenges

...ing of an ancient sculpture immersed for two millennia in the sea provided a unique opportunity to probe the long-term impact of a specific artificial substrate on biomineralizng organisms and the effects of biocorrosion," the report said. By evaluating the mineral layers and fossilized organisms on the statue...

Structural biology scores with protein snapshot

...The DAGK structure, Sanders said, "confirmed that this is a really strange kinase." The enzyme has a porch-like structure, with a wide opening for its substrate diacylglycerol and the active site at the top of the porch. "The active site looks nothing like any other kinase active site it's a unique architec...

Zebra mussels hang on while quagga mussels take over

...irst time somebody actually went and systematically looked at functional differences between the two species that would explain the different kinds of substrate that they could invade," she says. "In that sense, Suzanne has produced a really elegant and clever study. It has very concrete hypotheses and results...

Aluminum-oxide nanopore beats other materials for DNA analysis

...ing a technique called atomic layer deposition to produce a very thin film of aluminum oxide on a silicon substrate. Next, the central portion of the substrate is etched away, leaving the film as a suspended membrane. An electron beam is then used to create a very tiny hole a nanopore in the membrane. The...

MSU discoveries upend traditional thinking about how plants make certain compounds

...ts Anthony Schilmiller and Rob Last were part of a research team that has found that tomato plants use a different compound, neryl diphosphate, as the substrate for making monoterpenes. The difference is subtle, but the discovery will change the way terpene (compounds that are responsible for the taste and sme...
Substrate in Biological Technology

Unique Histochemical Substrate Permits Dual Staining In Animal Tissue

Daniel G. Flowers and Lloyd A. Culp, Ph.D. back to top ...

An Optimal DNA Microarray Substrate for the Identification of Fetal and Somatic Liver Stem Cells of the Rat

Dr. Frank Stahl GBF Gesellschaft fr Biotechnologische Forschung mbH (Society for Biotechnological Research) Introduction DNA microarrays are a key technology in modern molecular biotec...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results

...ments of its pivotal trial, including the use of the surrogate primary endpoint of the change in the amount of kidney interstitial capillary GL-3, the substrate that accumulates in the cells of Fabry patients. In addition, the FDA is in agreement that the Company is eligible to seek Accelerated Approval for A...

Neogen Reports 16% Increase in Revenues

...o saw a double-digit increase in sales of its proprietary D3 detectable needles, and an exceptional 12% growth in sales of its proprietary K-Blue((R)) substrate sold primarily to diagnostic test kit manufacturers. Neogen's Food Safety segment recorded a completely organic, broad-based FY 2009 revenue...

Nanopillars promise cheap, efficient, flexible solar cells

... practical applications as well as theoretical performance, the researchers made a flexible solar cell of the same design by etching away the aluminum substrate and substituting a thin layer of indium for the bottom electrode. They sheathed the whole solar cell in clear plastic (polydimethylsiloxane) to make a...

Bilayer graphene gets a bandgap

... Researchers then tried to tune the bilayer graphene bandgap by doping the substrate electrically instead of chemically, using a perpendicularly applied, contin...lectric fields shaped by the gate electrodes. Their nano-FET used a silicon substrate as the bottom gate, with a thin insulating layer of silicon dioxide between...
Substrate in Biological Products

EnzChek cellulase substrate *blue fluorescent, 339/452 from Invitrogen

Description: EnzChek cellulase substrate *blue fluorescent, 339/452...
Company:Invitrogen

Chicken Anti-Ras-related C3 botulinum toxin substrate 1 Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description: Ras-related C3 botulinum toxin substrate 1...
Company:GenWay Biotech, Inc.

TMB Slow Kinetic One Component HRP Microwell Substrate from BioFX Laboratories, Inc.

Description: TMB Slow Kinetic One Component HRP Microwell Substrate, 1 L...
Company:BioFX Laboratories, Inc.

ProtoArray Kinase Substrate Identification Application Kit from Invitrogen

Description: ...
Company:Invitrogen

Custom Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences

Description: Microarrays designed for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research built on the flexible and powerful Paraflo microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive Protein Kina...
Company:LC Sciences

Protein Kinase Substrate (PKS) Peptide Microarray - Comprehensive Service from LC Sciences

Description: LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays synthesized on Paraflo microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research. ...
Company:LC Sciences

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Substrate in Biological Definition

Substrate

The word substrate can mean the following: In biochemistry , a substrate is a molecule which is acted upon by an enzyme . In industrial printing , substrate is used to describe the base material that images will be printed onto. Depending on the printing process and end u...

Active site

...ive site allow the recognition and binding of the substrate . The active site in many enzymes can be inhibit... blocked when a molecule chemically similar to the substrate binds to the active site but cannot be processed b...del whereby the active site binds and encloses the substrate molecule. Often enzymes bond to their...

Alcohol

...after methanol ingestion is to administer ethanol. This will bind to alcohol dehydrogenase, preventing methanol from binding and thus its acting as a substrate . Chemistry of alcohols Preparation Laboratory There are three common methods: From alkyl halides : react with aqueous...

Allostery

...(T) or relaxed (R), and that relaxed subunits bind substrate more readily than those in the tense state. The tw...rs the T state over the R state The binding of substrate to one subunit causes all other subunits to assume...r, the sequential model dictates that molecules of substrate bind via an induced fit protocol. Namely, when a ...

Allostery

...(T) or relaxed (R), and that relaxed subunits bind substrate more readily than those in the tense state. The tw...rs the T state over the R state The binding of substrate to one subunit causes all other subunits to assume...r, the sequential model dictates that molecules of substrate bind via an induced fit protocol. Namely, when a ...

Cellulose

...e and rayon , and more recently Modal , a textile derived from beechwood cellulose. Cellulose is also used within the laboratory as a solid-state substrate for thin layer chromotography . Chemistry Cellulose monomers (beta-glucose) are linked together through 1,4 glycosidic bonds . Cellulose is...
Substrate in Biological Dictionary

Substrate

Substrate (building), Natural stone,masonry surface, ceramic & porcelain tiles. Substrate (aquarium), the material used in the bottom of an aquarium ... In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the sub...

UvrA

...s a high preference of binding the end of a ... The UvrA protein on its own binds preferentially to damaged DNA (Seeberg and ... Incubation of substrate G1 with UvrA and wild-type UvrB results in two retarded ... The UvrA protein forms a dimer that interacts with UvrB to form a heterotrim...

Saturation mutagenesis

...ity Based on Combinatorial Saturation Mutagenesis and. Logical Redesign of the Castor ... saturation mutagenesis at positions known to affect substrate ... ...

S1 nuclease

...mes more active on DNA than RNA. Its reaction products are oligonucleotides or single nucleotides with 5' phosphoryl groups. Although its primary substrate is single-stranded, it can also occasionally introduce single-stranded breaks in double-stranded... A nuclease is an enzyme capable of cleavin...

Ribozyme

...zyme ... More details on the Ligase Ribozyme . ... ... correspond to substrate and ribozyme as in reference 1. ... Hammerhead Ribozyme - Main Tutoria...nimal consensus structure for the hammerhead ribozyme is shown above. ... substrate is the green strand and much of the ribozyme is magenta. ... The nam...

Reporter Gene

...ene system, particularly useful in plant molecular biology. Several kinds of GUS reporter gene assay are actually available, depending of the substrate used: the term GUS staining refers... Xactagen has developed technology that makes reporter cells (also referred to as reporter gene assay...
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Breaking Biology News(10 mins):BGI reports a novel gene for salt tolerance found in wild soybean 2Baboons groom early in the day to get benefits later 2Molecular snapshots of oxygen formation in photosynthesis 2
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