Strategy

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

For the first time, scientists have foundthat bacteria can use a Sonar-like system to spot other cells (eithernormal body cells or other bacteria) and target them for destruction.Reported in the December 24 issue of Science, this finding explains howsome bacteria know when to produce a toxin that makes infection moresevere. It may lead to the design of new toxin inhibitors. “Blocking orinte...

Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy

Results from the first clinical trial of a therapeutic cancer vaccine combining the synthetic bacterial DNA sequence, CpG 7909 (ProMuneTM, Coley Pharmaceutical), with a peptide antigen were reported today in the Journal of Clinical Investigation. The paper shows that the CpG 7909 DNA sequence is safe, and increases the immune system's ability to recognize and destroy cancer cells. The Phase I stu...

Gene silencing technique offers new strategy for treating, curing disease

A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center. "Virtually every disease starts at the level of malfunctioning gene expression, or viral or bacterial gene expression," said Dr. David Corey, professor of pharmacol...

AIDS expert says global strategy needed to combat feminization of HIV/AIDS

Thomas C. Quinn, M.D., a Johns Hopkins physician and scientist, who has spent the best part of the last 25 years leading major efforts to combat HIV and AIDS throughout the world, is calling for global strategies and resources to confront the rapid "feminization" of the AIDS pandemic. Quinn, a professor of infectious diseases at Hopkins and a senior investigator at the National Institute o...

Asleep in the deep: Model helps assess ocean-injection strategy for combating greenhouse effect

In searching for ways to counteract the greenhouse effect, some scientists have proposed capturing the culprit---carbon dioxide---as it is emitted from power plants, then liquefying the gas and injecting it into the ocean. But there are pitfalls in that plan. The carbon dioxide can rise toward the surface, turn into gas bubbles and vent to the atmosphere, defeating the purpose of the whol...

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Rapamycin Optimized in 100 Liter Fermentor Using BioCommand Control Strategys

Researchers in New Brunswick Scientific's in-house labs have developed a unique controlstrategy to achieve high antibiotic expression levels in a pilot-scale fermentation process ofStreptomyces hygroscopicus. Using the BioFlo 6000 fermentor's on-line controller withtouchscreen interface augmented by the powerful supervisory capabilities of AFSBioCo...

Fire your CIO? If he's not implementing strategy, show him the door

, and the like, combined with the standard fare of maintaining IT operations faced by CIOs in other industries....

GE acquisition may boost "early" healthcare strategy

GE and Ab...

Tommy Thompson's Iowa strategy isn't far-fetched

Thompson, who was last elected governor of Wisconsin in 1998 and who resigned as U.S. Health and Human Ser...

Doyle announces $80M renewable energy strategy

Doyle said the money - which includes tax credits, low-interest loans, and grants that would come from business development fund allotments and the sale of...

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Strategy at Medicine News

AEterna's acquisition of Zentaris being followed up with its new product pipeline and clinical development strategy

AEterna Laboratories Inc., a biopharmaceutical company focused on the development of novel therapeutic treatments in oncology and endocrinology recently acquired the new German based biopharmaceutical company, Zentaris AG. Following this acquisition// the new entity has in the pipeline six clinical stage products and two preclinical stage products, in oncology and one product already approved and...

Novel Strategy To Combat Alzheimer’s Disease

Alzheimer’s disease (AD), characterized by progressive memory loss, decline in language skills and other cognitive impairments, has been a major threat to ageing population.// A recent paper in the October issue of FEBS Letters, reviews the different strategies in drug discovery. Hong-Yu Zhang, the author of the study, muses that the success of the present one-drug-one-target strategy i...

"Defensive Pessimism" Before Exam Results Not a Good Strategy

A new study by Margaret Marshall of Seattle Pacific University and Jonathon Brown of the University of Washington has found that the strategy// of expecting the worst results after an examination does not pay off in the long run and individuals who adopt such defensive pessimism are not better off than their normal counterparts. Reporting in the latest issue of the journal Cognition and...

WHO Devises New Global Strategy To Fight Tuberculosis

A new global strategy devised by the World Health Organization (WHO) would be adopted to effectively manage tuberculosis, an infectious disease that claims the lives of nearly 1.7 million people, worldwide //. The $56 billion global plan would be launched in January and targets reduction of prevalence of TB and the associated death rate by as much as 50% by the end of 2015. If this we...

HER-2 Positive Breast Cancer Patients May Benefit With a Combo Drug Strategy

According to researchers, Breast Cancer Patients with HER-2 Positive tumor who do not respond well to Herceptin alone could benefit// with a combination of drug Herceptin and one or more P13K-inhibiting agents. The research team at the University of Texas M.D. Anderson Cancer Center in Houston is due to conduct anther trial, after having successfully tested it on mice. The second stag...

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Generex Biotechnology Vaccine Strategy Presented at International Conference in London

WORCESTER, MA - May 24, 2007 - Generex Biotechnology Corporation(NasdaqCM:GNBT) announced today that Dr. Douglas Powell, Directorof Immunobiology at its wholly-owned Antigen Express subsidiary,has presented Antigen's vaccine development strategy at aninternational conference in London, UK. The international meeting,"Developing New Anti-Infective Agents - Challenges andOpportunities" (<a...

Study Shows Metabolic Strategy of Stressed Cell

Major St. Jude Study of Changes in Gene Activity and MetabolicEnzymes Show How Cells Respond to a Sudden Decrease in the Levelsof Coenzyme A, a Key Player in the Daily Biochemical Routines thatSupport Life MEMPHIS, Tenn., March 23, 2007 /PRNewswire/ -- Investigators atSt. Jude Children's Research Hospital have mapped out many of thedynamic genetic and biochemical changes that make up a ce...