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Strands in Medical News

Scientists Decode HIV Genome

...ion as single-stranded RNA rather than double-stranded DNA. Information encoded in RNA is more complex. The HIV RNA genome is huge, composed of two strands of almost 10,000 nucleotides each. Previously, scientists had managed to model only small regions of the HIV RNA genome. In this study, University ...

Heavy drinkers face significantly increased cancer risk

... cancer, lung cancer and prostate cancer," Benedetti added. "The strongest risk was for esophageal and liver cancer." "This study crystalizes many strands of evidence from different studies on different types of cancer and alcohol consumption," said Dr. Jack Siematycki, professor, Canada Research Chair ...

Scientists Track Impact of DNA Damage in the Developing Brain

...hed off a pathway for repairing damaged single DNA strands in an organ system, in this case the mouse brain a...ts growing scientific interest in damage to single strands of DNA. "A variety of human disease syndromes resu...ong been associated with unrepaired damage to both strands of DNA. Single-strand DNA damage is far more commo...

University of Leeds wins $18 million funding to improve the quality of our old age

... the University and the Leeds Teaching Hospitals NHS Trust, to create even better, more effective therapies. Their centre will combine two distinct strands of work the country's largest bioengineering unit and a world-leading research centre for artificial joint replacements both dedicated to creating n...

RNA snippet suppresses spread of aggressive breast cancer

...ead Member Robert Weinberg's laboratory, screened patient breast cancer samples for microRNAs with potential roles in metastasis. MicroRNAs are single strands of RNA about 21-23 nucleotides long. Within a cell, a single microRNA can fine-tune the expression of dozens of genes simultaneously. This capability ...

Wistar Institute team finds key target of aging regulator

...moves an acetyl group attached to a specific site (lysine at position 16 or K16) on histone H4histones are proteins that package and organize the long strands of DNA within the nucleus and also are central regulators in turning genes on and off. The study reveals that removal of this acetyl group by Sir2 nea...
Strands in Medical Technology

Heparin Use Prior to Endoscopic Vein Harvest Improves Graft Patency in Off-Pump Coronary Artery Bypass Patients

...g off-pump coronary artery bypass (OPCAB). Pre-heparinization was also linked to a significant reduction in the incidence and volume of residual clot strands within the vein. In EVH, a small incision is made in the leg, through which an endoscope is passed and the vein harvested for coronary artery byp...

In Rare Disorder, a Familiar Protein Disrupts Gene Function

...t encircles chromosomes during cell division. Cohesin's long-established role, called "canonical" by the authors, is to control chromatids -- the long strands that chromosomes form when they copy their DNA. However, said Krantz, one open question in biology has been, "What does cohesin do when cells ar...

St. Jude Study Finds Treatment With New Drug Might Make Tumor Cells More Sensitive to Therapy

...ue of the journal Cancer Research. ATM plays a critical role in repairing a type of DNA damage called double-strand breaks, in which each of the two strands making up this molecule are cut, according to Michael Kastan, M.D., Ph.D., director of the St. Jude Comprehensive Cancer Center. This process protects...

Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study

... resveratrol may impair the uptake of folic acid (vitamin B9) by intestinal cells. Folic acid is an essential nutrient required for repair of DNA gene strands and is utilized by the body to limit the amount of an undesirable blood protein called homocysteine. Optimal health benefits appear to be achieved w...

ProNAi Announces Preclinical Success for PNT2258 Therapeutic - Curative Events in Xenograft Mice for Difficult-to-Treat Non-Hodgkin's Lymphoma

...Ai(R) DNAi(R) (DNA interference) is a novel approach to targeting genomic DNA using sequence-specific therapeutic oligonucleotides, employing single strands of DNA to target and treat non-transcribed regions of genomes responsible for complex genetic diseases, such as cancer. By acting at the DNA level, ...

NIEHS Researchers Identify Enzyme Critical in DNA Replication

...le of replicating DNA, a process required to make new genomes for cell division. These enzymes, called DNA polymerases, were shown to copy the two DNA strands in only one of two possible directions. One strand of the double helix must be replicated first by a dedicated leading strand polymerase, followed sli...
Strands in Medical Products

Advanta™ ePTFE facial implants

Description:...of the facial area. This product is available in sheets and shaped geometries with and without reinforcement. Advanta™ PTFE round facial implant strands are packaged with and without an attached stainless steel trocar....
Company:Atrium Medical Corporation

FlexiGel Strands® Absorbent Wound Dressing

Description:... and entraps slough and necrotic debris within its strands to assist in debridement. The strands of the matrix are bound together by a matrix bridg...ption of the matrix material during use. FlexiGel strands is flexible, pliable, and non-adherent to aid in c...
Company:Smith & Nephew, Inc. - Orthopedics

AMS DURA II™

Description:... Positionable Penile Prosthesis The AMS DURA II positionable prosthesis is made of cobalt-chrome alloy strands for core strength that gives patients what they want most: ease of positioning, cosmetic concealment and adequate rigidity for pleasurable intercourse...
Company:AMS

Corkscrew™ II Suture Anchor

Description:...ease of starting will be accomplished with little effort. The Corkscrew II is supplied sterile and preloaded on a disposable handled inserter with two strands of #2 FiberWire suture or Tevdek suture. A Corkscrew Starter Awl is available should the surgeon encounter very hard bone and subsequent difficulties...
Company:Arthrex

High Beam TriLens Classic and Sport

Description:...ls known today. Minlon is lightweight and ensures safety and durability when using xenon light. Our 4.75 mm fiber optic cable holds 9,000 glass strands sheathed in our new ultra light BFW BLUE Opaque sheath, affording a lower profile than cables with half the light delivering capability. Choose...
Company:BFW, Inc.

Mainstay® ZIP Suture Anchors

Description:...ors that come in several different sizes and suture options. The ZIP anchor is offered in a 2.7mm, 3.5mm, and 4.5mm size with either one strand or two strands of #0, #2, or #5 suture. Needles are attached to each suture strand and the anchors are pre-loaded onto a disposable inserter....
Company:Stryker Corporation
Strands in Medical Dictionary

Venom

...vehicles from Venom Group International. ... Then scroll down to the section called "Scripting" and check ... As Venom , Brock could also shoot strands of the alien's substance in the form of ... Venom also possessed an extrasensory ability similar to Spider-Man's ... Venom official AOL Music ...

Lichen

...chen sclerosus? ... Brief and Straightforward Guide: What is Lichen ? ... Lichen is a kind of primitive plant species that's nothing more than strands of ... What is lichen ? ... Petula is one form of lichen and it is an unusual type. ... The most common cyanobacterium in lichen is Microcole...

Ebola

...ymptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. Ebola was first discovered in 1976, and since its discovery, different strands ... It is named after the Ebola River in Zaire, Africa, near where the first ... Brief and Straightforward Guide: What is Ebola ? ... There a...

Chromosomes

...are not needed ... Biology4Kids.com! The web site that teaches the basics of biology and life science to everyone! ... Scientists count individual strands of chromosomes . ... Biology4Kids.com! The web site that teaches the basics of biology and life science to everyone! ... When the chromatin comes...

Chromosome

... Genetic Disorder Guide Gene and ... Information about chromosome in the free online English dictionary and ... chromatid - one of two identical strands into which a chromosome splits during mitosis ... Eukaryotic Chromosome Structure ... shortest human chromosome contains 4.6 x ... In its mo...
Strands in Biological News

New cancer drug delivery system is effective and reversible

...ancer cells. To solve the cell-targeting problem, the U. of I. team turned its attention to small molecules called aptamers. "Aptamers are short strands of DNA or RNA; they are highly efficient binders, and are very easy to make, label and manipulate," said Zehui Cao, a postdoctoral researcher in the l...

New DNA and RNA aptamers offer unique therapeutic advantages

... New Rochelle, NY, August 5, 2009A novel class of drugs composed of single strands of DNA or RNA, called aptamers, can bind protein targets with a high strength and specificity and are currently in clinical development as treatments ...

DNA computation gets logical at the Weizmann Institute of Science

...d in something like this: Mortal(Socrates)?. To compute the answer, various strands of DNA representing the rules, facts and queries were assembled by a roboti...ical process. The answer was encoded in a flash of green light: Some of the strands had a biological version of a flashlight signal they were equipped with a ...

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... then proteins. Studies in both cells and a mouse model for cancer showed that they could promote the expression of MYC by transfecting cells with DNA strands containing DLX5. Too much DLX5, they found, led to too much MYC. When they knocked out expression of DLX5 in lung cancer cells, it resulted in decrea...

Scientists track impact of DNA damage in the developing brain

...hed off a pathway for repairing damaged single DNA strands in an organ system, in this case the mouse brain a...ts growing scientific interest in damage to single strands of DNA. "A variety of human disease syndromes resu...ong been associated with unrepaired damage to both strands of DNA. Single-strand DNA damage is far more commo...

Reveal the enemy

...c binding sites. If bacteria bind to the aptamers, the researchers detect a change in electrical voltage. Aptamers are synthetic, short DNA or RNA strands that can be designed and made to bind a specific target molecule. An aptamer that specifically binds to salmonella has recently been developed. The Sp...
Strands in Biological Technology

Bacteria pack their own demise

...reatures, people as well as bacteria, store their genetic information in the same way, i.e. in the DNA. Every human cell contains 46 neatly folded DNA strands that together measure two meters, while bacteria have to make do with around one millimetre of DNA. A piece of DNA containing the recipe for one chara...

Scientists create metal that pumps liquid uphill

...tant, Anatoliy Vorobyev, use an ultra-fast burst of laser light to change the surface of a metal, forming nanoscale and microscale pits, globules, and strands across the metal's surface. The laser, called a femtosecond laser, produces pulses lasting only a few quadrillionths of a seconda femtosecond is to a ...

Assembling cells into artificial 3-D microtissues, including a tiny gland

... of one cell and its complementary strand on another cell, the researchers assure that the two lock together exclusively. To get these specific DNA strands onto the cells, they used chemical reactions that do not interfere with cellular chemistry but nevertheless stick desired chemicals onto the cell surf...

Researchers discover a potential on-off switch for nanoelectronics

...n the tip and gold surface reduces to a single strand, like a necklace. When this strand finally breaks, nearby molecules can hop into the gap between strands and contact the gold electrodes, resulting in a sudden change in conductance. Using this technique, Venkataraman and colleagues, including Mark Hybert...

BioNanomatrix's Revolutionary Whole Genome Analysis Platform Named to MIT Technology Review's Annual 10 Emerging Technologies List

...n a massively parallel format. It can uniquely isolate and image very long strands of completely linearized DNA molecules in a dynamic flow, making it possibl...yses simultaneously. The technology's ability to image very long individual strands of DNA is also expected to facilitate such important analyses as structural...

Researchers control the assembly of nanobristles into helical clusters

...epoint canvas. The resulting capillary forcesthe wicking action or the ability of one substance to draw another substance into itcaused the individual strands to deform and to adhere to one another like braided hair, forming nanobristles. "Our development of a simple theory allowed us to further character...
Strands in Biological Products

Silencer Pre-designed siRNA, HPLC purified, annealed from Ambion

Description:...of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes each annealed siRNA by gel electrophoresis to confirm that the strands annealed properly. The result is premium quality siRNA that is purified and ready to use....
Company:Ambion

Silencer Pre-designed siRNA, standard purity from Ambion

Description:...of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes each annealed siRNA by gel electrophoresis to confirm that the strands annealed properly. The result is premium quality siRNA that is purified and ready to use....
Company:Ambion

Custom siRNA, PAGE purified from Ambion

Description:...of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes each annealed siRNA by gel electrophoresis to confirm that the strands annealed properly. The result is premium quality siRNA that is purified and ready to use....
Company:Ambion

Silencer Pre-designed siRNA, HPLC purified from Ambion

Description:...of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes each annealed siRNA by gel electrophoresis to confirm that the strands annealed properly. The result is premium quality siRNA that is purified and ready to use....
Company:Ambion

Custom siRNA, PAGE purified, annealed from Ambion

Description:...of all HPLC and PAGE purified oligonucleotides by analytical HPLC. Ambion also analyzes each annealed siRNA by gel electrophoresis to confirm that the strands annealed properly. The result is premium quality siRNA that is purified and ready to use....
Company:Ambion

Mung Bean Nuclease from Promega

Description:...rom both ends (1,2). Mung Bean Nuclease has been used for transcript mapping studies (3,4), for flushing staggered ends and for the separation of cDNA strands after synthesis with reverse transcriptase and DNA Polymerase I (5)....
Company:Promega
Strands in Biological Definition

Bacterial conjugation

... of DNA always runs from the F-positive towards the F-negative bacterium. If the F-plasmid is free, a nick is produced in one of the circular DNA strands of the plasmid. Then, the single-stranded DNA of the nicked strand is inserted into the recipiane bacterium (5'-end first). The now single-stranded pl...

Beta sheet

... such hydrogen bonds arranged in this way contributes to the sheet's stability and structural rigidity and integrity. The α-C atoms of adjacent strands stand 350 picometres (0.35 nm) apart. The side chains from the amino acid residues found in a β sheet structure may also be arranged such tha...

Sticky end/blunt end

...en complementary base pairs , providing specificity to the pairing of two strands of DNA. If two complementary strands of DNA are of equal length, then they will terminate in a blunt end , as i...

Chromosome

...ring prophase . (Two copies of the DNA molecule are now present) (5) Chromosome during metaphase . In the early stages of mitosis, the chromatin strands become more and more condensed. They cease to function as accessible genetic material and become a compact transport form. Eventually, the two matchin...

Chromosome walking

...identifying and sequencing long parts of a DNA strand, e.g., a chromosome . As the traditional chain termination method does not allow long DNA strands to be sequenced, this method works by dividing the long sequence into several consecutive short ones. The basic technique is as follows: A pr...

DNA

...chanical properties relevant to biology 6.1 strands association and dissociation 6.2 Circular DNA ... 6.5 Non-helical forms 7 Direction of DNA strands 7.1 Chemical nomenclature (5' and 3') 7....four kinds of nucleobases ("bases"). Because DNA strands are composed of these nucleotide subunits, they ar...
Strands in Biological Dictionary

Vascular bundles

... vascular bundles , which are randomly scattered ... ... into discrete strands called vascular bundles , each containing xylem and phloem. ... The c...ments separate into multiple ... Each vascular bundle contains multiple strands of tracheary elements. ... A Bundle of Marks. Vascular Tissue: plan...

Vascular bundle

...ments separate into multiple ... Each vascular bundle contains multiple strands of tracheary elements. ... The Spatial Arrangement of Vascular Bundle...ia, the free encyclopedia ... Vascular bundles ... ... into discrete strands called vascular bundles , each containing xylem and phloem. ... Aspect...

Trans-splicing

...mals, trans - splicing can be used to reprogram or interfere with specific ... Trans - splicing is an unusual process in which two separate RNA strands are ... We use the term ' trans - splicing region' to describe data that contain the ... In addition, trans - splicing was not detected in COT o...

Telomerase

... Telomerase is an enzyme that adds specific DNA sequence repeats to the 3' end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. The telomeres contain condensed DNA material, giving... telomera...

Supercoil

... In a "relaxed" double-helical segment of DNA, the two strands twist around the helical axis once every 10.4-10.5 base pairs of sequence. Adding or subtracting twists, as some enzymes can do, imposes strain. I...

Stringency

...ry, 11th ... stringency Reaction conditions - notably temperature, salt concentration(s) and ... At high stringency , duplexes form only between strands with perfect one-to-one ... Stringency of Tests for Random ... To gauge the stringency of a test, we conduct the test ... The stringency of t...
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