Man and mouse share genome structures
In the most detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlying cancer and human development. The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postd...Growth in the sea comes down to a struggle for iron
Scientists know that injecting iron into some major regions of the oceans can stimulate the growth of diatoms and other phytoplankton, but something odd occurs as these tiny marine plants continue to grow. They begin to starve in the midst of plenty, acting as though iron, an essential nutrient, still is in short supply. Why this happens is unclear, but the answer could be that iron sets off a ki...Newly-discovered class of genes determines ?and restricts ?stem cell fate
Research on adult stem cells found in the skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these genes has implications for therapies that involve t...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...Ecological destruction fuels emerging diseases
The destruction of habitat by human activity and the extinction of species around the world is more than a looming environmental catastrophe, warns a Canadian zoologist. This ecological damage also endangers human health by turning parasites into "evolutionary land mines." Dr. Daniel (Dan) Brooks, a parasitologist at the University of Toronto, says the decline of global biodiversity is li...Full-Configuration Camera Link NI PCIe-1429 from National Instruments Corporation
Description:The National Instruments PCIe-1429 is the industrys first PCI Express image acquisition board.With the NI PCIe-1429, you now can acquire images at the highest speeds, resolutions, and bit depths available for Camera Link cameras to perform demanding imaging applications such as synchronized data and image acquisition, fault analysis, and advanced motion tracking. In the past, acquiring ima...EBY100 S. cerevisiae Strain from Invitrogen
Description:The pYD1 Yeast Display Vector is specifically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglutinin yeast adhesion receptor which consists of two domains Aga1 and Aga2 to display recombinant protein on the surface of S. cerevisiae. T...Bio-Stack Twister II Microplate Handler from BioTek Instruments
Description:The Bio-Stack Twister II Microplate Handler is a high-capacity, plug-and-play bench top automation solution for integrating BioTeks washers, readers and liquid handling systems together with expandable microplate capacity, ultimate flexibility and intuitive and powerful software. Whether you are adding capacity to single devices or linking several modules together to complete a robotic system, th...Standard Protein Kinase Substrate (PKS) Peptide Microarray from LC Sciences
Description:Microarrays designed for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research built on the flexible and powerful Paraflo microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive Protein Kinase Substrate - Peptide Microarray Service. Our standard content PKS...Protein Kinase Substrate (PKS) Peptide Microarray - Comprehensive Service from LC Sciences
Description:LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays synthesized on Paraflo microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research. This comprehensive service includes preparation of your kinase sample, single or dual color enzymati...Purified Single-Stranded M13 DNA for Automated Sequencing
A streamlined and reliable method to obtain high-quality single-strandedDNA Stratagene M13 DNA purification kit allowseasy, quick, and reliable purification of bacteriophage single-stranded DNA. Theyield of single-stranded DNA recovered from phage lysa...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...Detecting Gastrin-Releasing Peptide Receptor by in situ PCR on Archived Tissue
In situ Adapter for the RoboCycler 40 Temperature Cycler allows rapidamplification of rare mRNA Department of Medicine, University of Illinois at Chicago Figure 1: RoboCycler 40 Temperature Cycler In Situ Adapter Syst...Efficiently Insert Unique Restriction Sites into Plasmid Vectors
Stratagene A 28-base insertion was introduced into a plasmid vector using theQuikChange site-directed mutagenesis kit.* Theinsertion created three unique restriction enzyme digestion sites. Plasmid DNAisolated from 9 o...Restriction Endonucleases Undergo Rigorous QC Testing to Ensure Optimal Performance
Stratagene Restriction endonucleases are used in many molecular biology protocols,making the functional purity of critical importance. Each restriction enzymepreparation must be free of contaminants that can potentiall...Feeling depressed? You may be at higher risk of STROKE
Those who suffer symptoms of depression are at an increased risk of stroke, according to researchers from the Centers for Disease Control and Prevention. In particular, depressed African Americans showed the largest increase in stroke risk. Those people with the highest levels of depression had a 73% increase in their risk of stroke. However, it is not clear if the depression actually c...Amphetamines Help Recovery of Stroke Patients
A new study from Doctors at UT Southwestern in Dallas soon report that amphetamines may speed up the recovery of speech in stroke patients who have lost the function. This study was done on patients who had suffered from ischemic stroke, or a stroke due to loss of blood and oxygen to the brain. Amphetamines were given to 30 stroke patients who lost their ability to spea...Serum Progesterone Helps Stratify Ectopic Pregnancy Risk
Measurement of serum progesterone levels may be helpful in deciding which emergency department patients with no strong clinical signs are at low risk of ectopic pregnancy, according to a report in the August issue of the Annals of Emergency Medicine. They measured progesterone levels in 716 first-trimester patients who presented to an emergency department with abdominal pain or...Genetic Dentistry: Your Dentist may be able to grow you a new set of Teeth.
Researchers at the University of Texas Health Science Center at San Antonio have successfully regrown mouse teeth in a petri dish from single mouse cells - and they think humans are next. They hope to push the research in the direction where they could take initial tissue from a [human] patient, put it in a culture dish and grow a tooth for them.To accomplish this seemingly futuristic fea...Cough Syrup Ingredient Linked to Stroke
Phenylpropanolamine (PPA),is a common ingredient found in many non-prescription cough and cold medications. Use of PPA-containing cough and cold remedies increased the risk of stroke by 23 percent. Dr.Ralph I. Horwitz, from Yale University's School of Medicine, says, "Case reports have linked exposure to PPA to the occurrence of hemorrhagic stroke." A hemorrhagic stroke results when...Castroviejo Corneal Trephine Set
Description:Set includes: trephine body and guard, two disposable blades and stainless steel sterilizing case. May be used freehand or with Elliot trephine handle. Adjustable stop calibrated in 0.2 increments. Polished finish. Most popular size or model....Graefe Strabismus Hook - Non-Magnetic
Description:#2 10 mm hook. Flat serrated handle with polished finish. Overall length: 5.5 inches....Manson Double Ended Strabismus Hook
Description:3 mm forked angled blades. Blade spread 7 mm. Flat serrated handle with polished finish. Overall length: 4.8 inches....New Advances in Gastric Diagnostics: Smaller is Better
In recent years, miniaturization has opened up exciting possibilities in the area of gastric diagnostics. New technology may make routine GI diagnostic procedures as simple as swallowing a vitamin pill-sized encapsulated unit in the not-too-far future, and the present reality is that these units are becoming valuable adjuncts to traditional diagnostics. Capsule endoscopy (enteroscopy...Point of Care Strep Tests Speed Treatment, Lower Costs
Beta-hemolytic group A streptococcus (S. pyogenes) is the most common bacterial agent associated with upper respiratory tract infections. Although it usually involves mild symptoms (such as headache, fever or abdominal pain) if left untreated streptococcal infection can worsen and become life-threatening. Early diagnosis and treatment of group A streptococcal pharyngitis has been shown to red...Genetic Analysis Systems Enter the Clinical Mainstream
Like many other diagnostic regimes that were previously restricted to large specialty laboratories, genetic analysis is entering the clinical mainstream. Smaller, simpler analyzer systems are now suitable and affordable for hospital or large physicians group labs, while some genetic test kits are becoming available for primary point of care locations such as clinics and physician offices.<...Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
- Results Fail to Demonstrate Meaningful Placebo Adjusted WeightLoss; Obesity Program to be Discontinued NEW YORK, July 09, 2007 /PRNewswire-FirstCall/ -- ManhattanPharmaceuticals, Inc. today announced results of the company's twoPhase 2a clinical trials of oral Oleoyl-estrone (OE). The resultsof both randomized, double-blind, placebo-controlled studies, onein common obesity and the other...