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Stomatitis in Medical News

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

...cent), fever (21 percent vs 31 percent), nausea (46 percent vs 63 percent), stomatitis (41 percent vs 15 percent), vomiting (33 percent vs 44 percent), diarrhea (...ent), alopecia (9 percent), vomiting (8 percent), diarrhea (5 percent), and stomatitis (5 percent) Please visit www.doxil .com for the full Prescr...

Telik Presents Results at ASCO From ASSIST-5 Trial of TELCYTA in Platinum Refractory and Resistant Ovarian Cancer

...severity in both arms. In addition, 17% Grade 2-3 stomatitis and 9% Grade 2-3 palmar-plantar erythrodysesthesia...he TELCYTA plus PLD arm, compared to 23% Grade 2-3 stomatitis and 21% Grade 2-3 PPE in the PLD control arm. Grad...LCYTA may ameliorate the incidence and severity of stomatitis and PPE known to be associated with PLD. There wa...

Virus evolution topic of Darwin talk at UH April 2

... evolve. Turner often performs basic research on non-dangerous viruses that serve as models for important pathogens. An example is the vesicular stomatitis virus that does not cause disease in humans but provides an excellent model for the sometimes deadly Dengue virus and other viruses transmitted by mos...

Twenty New Abstracts on Oral Xeloda(R) (capecitabine) Featured at the 31st San Antonio Breast Cancer Symposium

...irment, dose reduction is required. The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modifi...

HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity

...zziness (including vertigo), headache, neurologic sensation disorders (including paraesthesias), cough, nasopharyngeal pain, diarrhea, abdominal pain, stomatitis and mouth ulceration, nausea, hepatic enzymes increased, rash, pruritus, musculoskeletal pain, pyrexia, fatigue (including asthenia and malaise). Ab...

Data Show that Abbott's HUMIRA(R) (adalimumab) Reduced the Signs and Symptoms of Ankylosing Spondylitis Up to Three Years

...zziness (including vertigo), headache, neurologic sensation disorders (including paraesthesias), cough, nasopharyngeal pain, diarrhea, abdominal pain, stomatitis and mouth ulceration, nausea, hepatic enzymes increased, rash, pruritus, musculoskeletal pain, pyrexia, fatigue (including asthenia and malaise). Ab...

Abbott Announces HUMIRA(R) (adalimumab) Approved in Japan for the Treatment of Rheumatoid Arthritis

...zziness (including vertigo), headache, neurologic sensation disorders (including paraesthesias), cough, nasopharyngeal pain, diarrhea, abdominal pain, stomatitis and mouth ulceration, nausea, hepatic enzymes increased, rash, pruritus, musculoskeletal pain, pyrexia and fatigue (including asthenia and malaise). ...

Researchers train the immune system to deliver virus that destroys cancer in lab models

...urrence. The study appeared in the Dec. 9 online issue of Nature Medicine. The technology combines infection-fighting T-cells with the vesicular stomatitis virus that targets and destroys cancer cells while leaving normal cells unharmed. The study, which has not yet been replicated in humans, is significa...

Xeloda(R), Taxotere(R) and Herceptin(R) Combination Study Suggests Clinical Benefit in Invasive Breast Cancer with Shortened Treatment Cycle

...l impairment, dose reduction is required. The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modific...

ImClone and Bristol-Myers Squibb Announce Joint Agreement With Merck KGaA to Co-Develop and Co-Commercialize ERBITUX(R) in Japan

...fection without neutropenia (35%, 17%), headache (33%, 11%), fever (30%, 18%), insomnia (30%, 15%), cough (29%, 19%), dermatology-other (27%, 6%), and stomatitis (25%, 10%). About ImClone Systems ImClone Systems Incorporated is a fully integrated biopharmaceutical company committed to advancing oncology care ...
Stomatitis in Medical Technology

Induction Chemotherapy Followed by ChemoRadiotherapy Increased Time-to-Treatment Failure Compared to ChemoRadiotherapy Alone in Patients With Unresectable Locally Advanced Head & Neck Cancer

...ategy (IC+CRT) compared to 44.5% of those patients treated with CRT alone (p=0.002). The most frequent severe (grade 3-4) adverse reactions were stomatitis (44% for IC+CRT vs. 31% for CRT) and febrile neutropenia (10% for IC+CRT vs. 1% for CRT). Other adverse events included neutropenia and asthenia. ...

New Overall Survival Study Results Confirm Oral Xeloda(R) plus Oxaliplatin (XELOX) is Comparable to FOLFOX-4 for the First-Line Treatment of Advanced Colorectal Cancer

...mpairment, dose reduction is required. The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modifi...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

...ded: asthenia (40% vs 51%), fever (21% vs 31%), nausea (46% vs 63%), stomatitis (41% vs 15%), vomiting (33% vs 44%), diarrhea (21% vs 35%), anorexia... (7%), fever (8%), alopecia (9%), vomiting (8%), diarrhea (5%), and stomatitis (5%) Please see accompanying full Prescribing Information, includ...

Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment

...zziness (including vertigo), headache, neurologic sensation disorders (including paraesthesias), cough, nasopharyngeal pain, diarrhea, abdominal pain, stomatitis and mouth ulceration, nausea, hepatic enzymes increased, rash, pruritus, musculoskeletal pain, pyrexia, fatigue (including asthenia and malaise). Adve...

RAD001 Combined with Sandostatin LAR(R) Depot and as Monotherapy Controls Growth of Rare Pancreatic Neuroendocrine Tumors

...ival had not been reached at the time of data evaluation. The most frequent adverse events in patients taking RAD001 with Sandostatin LAR Depot were stomatitis (49%), rash (40%), diarrhea (29%), fatigue (33%), nausea (33%), vomiting (13%), asthenia (11%), anemia (18%) and weight decrease (16%). About NET ...

Nearly 60 New Studies of Oral Xeloda(R) (capecitabine) Featured at the 44th American Society of Clinical Oncology Annual Meeting

...l impairment, dose reduction is required. The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modific...

Novel Xeloda(R) Dosing Schedule May Offer Well-Tolerated Alternative for Treatment of Advanced Breast Cancer

...l impairment, dose reduction is required. The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modific...

Over 30 New Studies of Oral Xeloda(R) Featured at the 2008 Gastrointestinal Cancers Symposium

...l impairment, dose reduction is required. The most common adverse events (greater than or equal to 20%) of Xeloda monotherapy were diarrhea, nausea, stomatitis and hand-foot syndrome. As with any cancer therapy, there is a risk of side effects, and these are usually manageable and reversible with dose modific...

US Oncology Research Network Presents Clinical Studies at San Antonio Breast Cancer Symposium

... 39 (25-55) The most frequent Grade 3-4 toxicities were neutropenia (77 percent), diarrhea (9 percent), hand-foot syndrome (8 percent), and stomatitis (7 percent). Decreased left ventricular ejection fraction (LVEF) <50 percent occurred in 4 of 40 pts receiving FEC75+H but there was no heart failur...

Celator(R) Pharmaceuticals Reports CPX-351 Shows Anti-Cancer Activity in Leukemia Patients

...n safely administered up to and including 101 units/m2 (=101 mg/m2 of cytarabine and 44mg/m2 of daunorubicin). Non-hematologic adverse events included stomatitis (10/27 patients), skin rash (10/27), diarrhea (9/27), nausea (7/27), vomiting (5/27) and alopecia (2/27). The study has shown that CPX-351 is capable ...
Stomatitis in Medical Definition

Pathology

...s disease - Mucus retention cyst - Mumps - Necrotizing sialometaplasia - Ranula - Sialadenitis - Sialolithiasis - Sjogren's syndrome - stomatitis - Xerostomia Tongue Geographic tongue - Fissured tongue - Glossitis - Glossodynia v • d • e He...
Stomatitis in Medical Dictionary

Stomatitis

Stomatitis is an inflammation of the mucous lining of any of the structures in the mouth, which may involve the cheeks, gums, tongue, lips, throat, and roof or floor of the mouth. The inflammation can be caused by conditions... An aphthous ulcer, also known as a canker sore, is a type o...

Oral candidiasis

... Oral thrush information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, ... Candidiasis (Handbook of Diseases) stomatitis and ... diagnosis and treatment of oral candidiasis infection can be a relatively ... makes oral candidiasis so amenable to treatment....

Mouth Ulcers

...ymptom of a disease ... Treatments for mouth ulcers ... Aphthous stomatitis is a common cause of recurrent mouth ulcers . ... Recurrent mouth ul...otally free from ... Mouth ulcers , oral mucositis, canker sores, stomatitis - causes and treatment of mouth ulcers . ... What Causes Canker Sores...

Aphthous ulcers

...ashington WA ... Aphthous ulcers are also known as canker sores. ... herpes, however, aphthous ulcers cannot spread from ... Aphthous stomatitis is an illness that causes small ulcers to appear in the ... ulcers in the mouth, usually inside the lips, on the cheeks, or on the tongue ... ...
Stomatitis in Biological News

New chemotherapy combo produces side effects, but no extra efficacy, in early breast cancer patients

...appears on the palms of the hands and soles of the feet, and which can be very painful if untreated. They also found increased rates of nail changes, stomatitis (inflammation of the mucous lining the mouth and throat), and diarrhoea. The scientists now intend to follow up their work by correlating the respo...

Jefferson scientists find rabies-based vaccine could be effective against HIV

...mmune system boosts, but didn’t see enhanced immune responses. They then developed a new vector, a viral surface protein from another virus, vesicular stomatitis virus (VSV). Two years after the initial immunization, they gave a booster vaccine with the rabies-VSV vector, and saw SIV/HIV-specific immune respons...

Researchers report breakthrough against world’s deadliest viruses

... to go." The study describes how Canadian researchers developed the vaccines by replacing a surface protein in an animal pathogen, called vesicular stomatitis virus, with a surface protein from either the Ebola or Marburg viruses. Following extensive work, including trials with mice and guinea pigs, the PHAC...
Stomatitis in Biological Technology

REMERON(R) Now Approved in Japan for the Treatment of Depression in Adult Patients

..., and a third patient developed severe neutropenia. All patients recovered after discontinuation of therapy. If a patient develops sore throat, fever, stomatitis or other signs of infection, along with low WBC, treatment with REMERONSolTab(R) should be discontinued and the patient should be closely monitored. ...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...) included: asthenia (40% vs 51%), fever (21% vs 31%), nausea (46% vs 63%), stomatitis (41% vs 15%), vomiting (33% vs 44%), diarrhea (21% vs 35%), anorexia (20% v...asthenia (7%), fever (8%), alopecia (9%), vomiting (8%), diarrhea (5%), and stomatitis (5%) Please see accompanying full Prescribing Inform...

Mathematical models reveal how organisms transcend the sum of their genes

...o behavior?" He and Lim, now a postdoctoral fellow at the University of California-Berkeley, computationally modeled the lifecycle of the vesicular stomatitis virus (VSV), a well-studied virus with only five genes and years of background research on its growth and function. Virologists have previously cr...

Telik Announces Top-Line Results From Assist-5 Trial of Telcyta(R) in Combination With Pegylated Liposomal Doxorubicin in Platinum Refractory and Resistant Ovarian Cancer

...lar in incidence and severity on both arms. Seventeen percent Grade 2 and 3 stomatitis and 9% Grade 2 and 3 palmar-plantar erythrodysesthesia (PPE) were observed on the Telcyta plus PLD arm, compared to 23% Grade 2 and 3 stomatitis and 21% Grade 2 and 3 PPE on the PLD control arm. Grade 4 PPE (2%) was only...

Otsuka Pharmaceutical and PDL BioPharma Close Sale of IV Busulfex

...void becoming pregnant as busulfan may cause fetal harm. The most common nonhematological adverse events were nausea (92% mild/moderate, 7% severe), stomatitis (71% grade 1-2, 26% grade 3-4), vomiting (95% mild/moderate), anorexia (64% mild/moderate, 21% severe), diarrhea (75% mild/moderate, 5% grade 3-4), in...

New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence Humanized Renilla GFP Reporter

... The pFB-hrGFP retroviral reporter vector is available as plasmid DNA and as a transduction-ready, replication-incompetent, vesicular stomatitis virus (VSV)-G pseudotyped high-titer retroviral supernatant. In plasmid form, the pFB-hrGFP retroviral vector must be packaged i...

Safe Production of High-Titer Retrovirus

...tural MMLV variants and are all relatively labile; they are considered relatively safe compared with other viral systems. The vesicular stomatitis virus G protein (VSV-G) 5 is rapidly becoming the most popular env protein. Unlike the other three MMLV-derived env proteins which recognize cell...
Stomatitis in Biological Products

Human Interferon Gamma Bioassay Services from PBL InterferonSource

Description:..., although assay times may vary. The bioactivity of human interferon gamma is measured using human mesothelioma cells (H226) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 30-60 u/ml. Standard for Human IFN gamma (NIH reference: Gg23-901-530)....
Company:PBL InterferonSource

Pig Interferon Alpha Bioassay Services from PBL InterferonSource

Description:...samples, although assay times may vary. The bioactivity of pig interferon alpha is measured using bovine kidney cells (MDBK) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 15-30 u/ml. Units are determined with respect to the Human IFN alpha 2a standard (NIH reference: Gxa01-901-535)....
Company:PBL InterferonSource

Human Interferon Beta Bioassay Services from PBL InterferonSource

Description:...amples, although assay times may vary. The bioactivity of human interferon beta is measured using monkey kidney cells (Vero) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 20-40 u/ml. Standard for Human IFN beta (NIH reference: Gxb02-901-535)....
Company:PBL InterferonSource

Human Interferon Omega Bioassay Services from PBL InterferonSource

Description:...mples, although assay times may vary. The bioactivity of human interferon omega is measured using bovine kidney cells (MDBK) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 15-30 u/ml. Standard for Human IFN omega (NIBSC Code: 94/754)....
Company:PBL InterferonSource

Human Interferon Alpha Bioassay Services from PBL InterferonSource

Description:...y. The bioactivity of human interferon alpha is measured using bovine kidney cells (MDBK) or human mesothelioma cells (H226) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 15-30 u/ml (MDBK), 5-10 u/ml (H226). Standard for Human IFN alpha 2a (NIH reference: Gxa01-901-535)....
Company:PBL InterferonSource
Stomatitis in Biological Definition

Arbovirus

...fferent families and even orders can be arboviruses. List of arboviruses (not complete): Dengue fever Ross River virus Vesicular stomatitis virus West Nile virus Yellow fever ...

RNA virus

...viridae : Mumps Picornaviridae : Polio Reoviridae Retroviridae : Human Immunodeficiency Virus Rhabdoviridae : Rabies - Vesicular stomatitis virus Togaviridae Filoviridae : Ebola See also DNA virus Virus classification ...

Vesicular stomatitis virus

... |- valign=top |Species:|| Vesicular stomatitis Indiana virus |- valign=top |Species:|| Vesicular stomatitis New Jersey virus Vesicular stomatitis virus (VSV) is a virus in the family Rhabdovi...
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