FDA approves VYVANSE, first and only once-daily prodrug stimulant to treat ADHD in adults
Basingstoke, U.K. and Philadelphia, PA April 23, 2008 Shire plc (LSE: SHP, NASDAQ: SHPGY,), the global specialty biopharmaceutical company, today announced that it has received approval from the U.S. Food and Drug Administration (FDA) for VYVANSE (lisdexamfetamine dimesylate), for the treatment o...
Growth Hormone Stimulant Packs Healthy Aging
Researchers report that a new drug developed, which is still under investigation was proved to stimulate growth hormone, helping the elderly age //in a healthy manner and also showed health longevity in a 100 year old women.
A steady growth in the aging research field was being portraited fro...
Cocaine Acts As Suppressant Not Stimulant In Genetically Altered Mice
Researchers at the Ohio State University have found that cutting off the reward pathway of cocaine on mice by genetically altering a vital target in the brain of the mice makes them shun cocaine//.
Howard Gu, the study’s lead author and an associate professor of pharmacology and psychiatry at...
With Autism, Diet Restrictions May Do More Harm Than Good
Medications that autistic children take can also interfere with appetite and eating.
"In our study, around 50 percent of children were on stimulant
medications, and those might affect appetite and might have something to do with issues with food," Ibrahim said.
Keith A. Young, vice chairman fo...
Consumer Reports to Parents: Think Twice About Free Prescription ADHD Drug Samples for Your Children
And there is another hitch: a recent study shows that at least one ADHD stimulant
drug, methylphenidate (Ritalin), may only work for a few years. There is li...th their child's doctor about whether the drugs are still working since all stimulant
drugs, along with Strattera (a non-stimulant), may have long-term risks, in...
VYVANSE CII provided significant efficacy at 14 hours in adults with ADHD
...stration during a simulated workplace environment study in adults with Attention Deficit Hyperactivity Disorder (ADHD). VYVANSE is the first approved stimulant
for adults with ADHD to be evaluated in this setting, and these data were presented today at the 49th annual New Clinical Drug Evaluation Unit meeting...
ADHD Drugs Linked to Sudden Death in Kids
MONDAY, June 15 (HealthDay News) -- stimulant
medications commonly prescribed to treat attention... research finds.
Children and teens taking ADHD stimulant
medications were seven times more likely to die su...e out confounding factors, the association between stimulant
use and sudden death was still significant," said ...
Stimulant Chewing Gum Can Be Dangerous for Kids
THURSDAY, May 28 (HealthDay News) -- stimulant
chewing gum can be dangerous if used excessively b...r learned that the boy had consumed two packets of stimulant
chewing gum within a four-hour period. The two pac...mptoms from those found in our patient. The use of stimulant
chewing gum should be considered in cases of caffe...
ADHD Treatment Guide: How to Safely, Effectively Use Medications and Non-Drug Therapies to Treat Attention Deficit Disorder
...n accurate ADHD diagnosis while considering common related conditions like depression and anxiety disorder
Evaluating the dozens of popular stimulant
and non-stimulant ADHD medications on the market today
Adjusting your type and dosage of ADHD medication to ensure the greatest individual ...
Methamphetamine Use Triples Among Pregnant Rehab Patients
...niversity of Chicago Medical Center.
Results of the study are published in the June issue of Obstetrics & Gynecology .
Methamphetamine is a stimulant
that's highly addictive. It can be taken orally, snorted, injected or smoked, according to the U.S. National Institute on Drug Abuse (NIDA). Treatment...
Stimulant in Medical Technology
Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD
In a clinical study of adults, VYVANSE taken once-daily significantly
improved the symptoms of ADHD within one week
PHILADELPHIA, Oct. 7 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP,
Nasdaq: SHPGY), the global specialty biopharmaceutical company, today
announced that a study published in th...
Schering-Plough Announces Phase III Data for Sustained Follicle Stimulant
Corifollitropin alfa meets primary endpoints in ENGAGE Trial
KENILWORTH, N.J., July 8 /PRNewswire-FirstCall/ -- Schering-Plough
Corp., (NYSE: SGP ) announced today that corifollitropin alfa, its
experimental, sustained follicle stimulant
(SFS) met its primary endpoints
in the Phase III ...
New Data Focuses on Abuse of Stimulant Medication
New Data Suggests Less Abuse-Related Effects For OROS(r)
Two New Studies Highlight Potential Benefit of Unique OROS(r)
SAN DIEGO, CA, May 22, 2007 - Stimulant
drug abuse remains an
ongoing concern for parents and physicians who prescribe
medications to treat Attenti...
Addrenex Pharmaceuticals Reports Positive Results in Second Phase 3 Study of ADHD Medication
...emonstrating that the combination of Clonicel with stimulant
medications provided statistically significant imp...hyperactivity disorder (ADHD) symptoms compared to stimulant
Clonicel is the company's lead com... as both a monotherapy and as an add-on therapy to stimulant
medication for children and adolescents with ADHD....
Schering-Plough's Investigational Oral Thrombin Receptor Antagonist Meets Primary Endpoint in a Newly Published Study
"In this study, TRA, when given with aspirin and clopidogrel, was able to inhibit the aggregation of platelets even when exposed to a very potent stimulant
(TRAP-thrombin receptor agonist peptide)," said Enrico Veltri, M.D., group vice president of global clinical research, cardiovascular and metabolic di...
Recent Study Demonstrated VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Improvements in Behavior, Inattention, and Math Test Scores from 1.5 Hours up to 13 Hours following Administration in Children with ADHD
... VYVANSE is the first oral ADHD stimulant
medication with published data
demonstrating symptom control at 13 hours post-dose in a pediatric clinical
CHICAGO, Oct. 29 /PRNewswire-FirstC...
Head-to-Head Study Demonstrates Focalin(R) XR Offers Faster and Better Symptom Control than Concerta(R)1 in Early Part of ADHD Patients' Day
...tion in patients with a prior
history of seizures or EEG abnormalities. Difficulties with accommodation
and blurring of vision have been reported with stimulant
Focalin XR should be given cautiously to patients with a history of
drug dependence or alcoholism. Chronic abusive use ca...
Catalyst Pharmaceutical Partners, Inc. Begins Enrollment for U.S. Phase II Clinical Trial of CPP-109 in Patients with Methamphetamine Addiction
About Methamphetamine Addiction
Methamphetamine is a highly addictive stimulant
that affects the
central nervous system. Abuse of the drug leads to devasta...proximately 535,000 patients
sought treatment for methamphetamine and other stimulant
abuse in 2006. In
addition, according to the 2006 SAMHSA Survey, an estimat...
Alexza Announces Preliminary Results From its AZ-002 (Staccato(R) Alprazolam) Phase 2a Proof-of-Concept Trial in Patients With Panic Disorder
...ase of the study received a Staccato device (randomized to
either 1 mg AZ-002 or placebo) and an intravenous administration of
doxapram, a respiratory stimulant
used to induce a simulated panic attack.
About Symphony Allegro
In December 2006, Alexza entered into a collaboration with Symphony
Capital LLC, a...
CNS Response, Inc. Provides Review of Poster Session Delivered at the American Psychiatric Association 161st Annual Meeting
...onths, and 2 years (for 4 patients). The medications selected from rEEG
correlations involved combinations from many different classes of
medications in four Eating Disorder patients did not
result in appetite suppression or weight loss. These results are consistent
with recent findings ...
Stimulant in Medical Products
Erythropoietin RIA Test
Description:... Erythropoietin (EPO) is the primary known naturally-occurring stimulant
of red blood cell production. The predicted molecular weight of human EPO is 18.2 kDa. Due to N-glycosylation, the circulating form of EPO has an esti...
Company:Diagnostic Systems Laboratories, Inc.
Stimulant in Medical Definition
...works of Aristotle and Avicenna as a remedy with antiseptic and general stimulant
properties used in Caucasus mountains . Most scientists agree that people ...in reasonable quantities. Research suggested that mumijo has antiseptic and stimulant
properties, so it tends to increase wound healing rate and produce better r...
Stimulant in Medical Dictionary
...addiction to prescription stimulants ... stimulant
drugs such as cocaine, "crack," amphetamines, and...... Stimulants are not intended for use ... stimulant
drugs are drugs that temporarily increase alertne...timulants " Categories: Psychoanaleptics ... stimulant
Drugs have come to include Prescription Stimulan...
... health, fitness, and lifestyle destination... stimulant
ADHD Medications: Methylphenidate and Amphetamines...e of drug. ... Ritalin , Methylphenidate is a stimulant
used to treat attention-deficit ... Ritalin in...and cocaine. Individuals abuse Ritalin for its stimulant
effects, ... Learn more about Ritalin or met...
... abuse " ... Brief and Straightforward Guide: What Is Laxative Abuse ? ... Laxative abuse is overuse of such substances, particularly stimulant
drug based ... Laxative Abuse - EDTreatmentCenters.com. Laxative abuse can cause many health complications. ... Laxative abuse is wh...
...aloid suffix -ine, forming cocaine . It is both a stimulant
of the central nervous... More about Cocaine ...... Cocaine is a strong central nervous system stimulant
that increases levels of ... Information about.... Cocaine is presently the most abused major stimulant
in America. ... Cocaine has powerful psychologic...
...t; in addition to the alkaloid suffix -ine, forming cocaine . It is both a stimulant
of the central nervous... Cocaine Abuse information by Drugs.com, i...nce of cocaine abuse among ... Cocaine is a powerfully addictive stimulant
that directly affects the brain. ... Drugs of Abuse - Cocaine ... As c...
Caffeine in the diet
... in the diet . ... Caffeine can be completely restricted in a child's diet since there is no ... Caffeine : Caffeine is a mild alkaloid stimulant
made by some plants. It is found in coffee beans, tea leaves, and ... to the amount of caffeine in an ... It can also enhance the effects of o...
... Caffeine is a bitter, white crystalline xanthine alkaloid that is a psychoactive stimulant
drug. Caffeine was discovered by a German chemist, Friedrich Ferdinand Runge, in 1819. He coined the term "kaffein", a chemical... Mor...
...rties can be referred to... Amphetamine is a stimulant
and is used to trat narcolepsy and attention de... catecholamine release. ... Amphetamine is a stimulant
and an appetite suppressant. ... Home >> D... ... Amphetamine , any of a group of powerful stimulant
drugs that act on the central nervous system the...
Stimulant in Biological News
Genetic study confirms the immune system's role in narcolepsy
...e able to develop drugs that block the protein's abnormal activity and prevent the onset of the disorder," says Dr. Mignot. Current treatments such as stimulant
drugs for combating daytime sleepiness and antidepressants for cataplexy are only able to control symptoms, and do not address the underlying loss of ...
Distinguishing single cells with nothing but light
...n time-critical areas, such as cancer research and immunology.
"There's an obvious desire among cell researchers to be able to deliver a controlled stimulant
to a single cell and then study its response over time," says Berger. "The clinical insights that might arise are currently in the realm of speculatio...
Studies examine genetic determinants of ADHD
...may someday be used to predict which children respond most favorably to the stimulant
medications used to treat ADHD. It demonstrated that, although there are likely to be genetic factors that are associated with stimulant
efficacy in children with ADHD, there are no single genes with a very large...
New hybrid plants could prompt more prodigious pepper production in Southwest
... Resource Center, capsaicin is already used as a "topical anti-arthritic and anti-inflammatory agent" and is "generally recognized as a powerful local stimulant
with no narcotic effect."
Additional research indicates capsaicin may have cancer-fighting properties and facilitate insulin production. It also has...
Adolescent girls with ADHD are at increased risk for eating disorders, study shows
...d than girls without ADHD. Mikami said she believes these factors could contribute to the bulimia nervosa symptoms.
"An additional concern is that stimulant
medications used to treat ADHD have a side effect of appetite suppression, creating a risk that overweight girls could abuse these medicines to encour...
Effective ADHD treatment found for children with fragile X syndrome
...th FXS also suffer from attention deficit and/or hyperactivity disorder (ADHD), which complicates social relationships at home and at school. Although stimulant
medication such as Ritalin is often successfully used to treat children with ADHD, studies have shown that while it is effective in children with ment...
ASU research shows connection between testosterone, dietary antioxidants and bird coloration
...ate in 35 male and female zebra finches. They surprisingly found that when they administered testosterone implants to zebra finches that it acted as a stimulant
to the immune system. They went on to show that carotenoids acquired from food and circulating through the blood were changing in ways that were linke...
Fruit fly study identifies gene mutation that regulates sensitivity to alcohol
...esponse to alcohol. Manipulating these genetic variants, the researchers generated flies with greater and lesser sensitivity to alcohol's sedative and stimulant
The research team also detailed how signaling proteins encoded by the RhoGAP18B gene variants played an important role in reorganizing c...
Research links 'ecstasy' to survival of key movement-related cells in brain
...nked to decreased brain activity.
MDMA, chemically known as methylenedioxymethamphetamine and sold and used illegally as "ecstasy," is a synthetic stimulant
that prompts the secretion of large amounts of the neurotransmitters serotonin, dopamine and norepinephrine in the brain. This secretion can lead to p...
Ecstasy can harm the brains of first-time users
...tion, we found a relative decrease in verbal memory performance in ecstasy users compared to non-users.?
Ecstasy is an illegal drug that acts as a stimulant
and psychedelic. A 2004 survey by the National Institute on Drug Abuse (NIDA) found that 450,000 people in the United States age 12 and over had used ...
Stimulant in Biological Technology
FDA Approves VYVANSE(TM) (lisdexamfetamine dimesylate), the First and Only Once-Daily Prodrug Stimulant to Treat ADHD in Adults
Within the First Eight Months Since its Introduction in the United States, VYVANSE has Achieved Over One Million Prescriptions
In a Clinical Study With Adults, VYVANSE was Shown to Significantly Improve the Symptoms of ADHD (Inattention, Hyperactivity and Impulsivity)(1)
Study Published in Child and Adolescent Psychiatry and Mental Health Demonstrated Once-Daily Vyvanse(R) (lisdexamfetamine dimesylate) CII Provided Significant Improvement of ADHD Symptoms for Children at 13 Hours After Administration
...blished data are the first to have shown duration of effect of an oral ADHD stimulant
in children aged 6 to 12 at 13 hours after administration. Physicians and ...ours) up to 13 hours postdose. Vyvanse is now the first and only oral ADHD stimulant
treatment to have efficacy at 13 hours after administration for pediatric p...
Study Showed VYVANSE(R) (lisdexamfetamine dimesylate) CII Provided Significant Efficacy at 14 Hours After Administration in Adults with ADHD in an Adult Simulated Workplace Environment
... VYVANSE is the first stimulant
to establish duration of efficacy from two hours up to 14 hours after admin...ntion Deficit Hyperactivity Disorder (ADHD). VYVANSE is the first approved stimulant
for adults with ADHD to be evaluated in this setting, and these data were p...
Schering-Plough Announces Phase II and III Data for Corifollitropin Alfa
... Single-dose of investigational sustained follicle stimulant
achieves similar efficacy to daily injections of follitropin beta given ove...gy (ART) program. Corifollitropin alfa is designed as a sustained follicle stimulant
(SFS) with the same pharmacodynamic profile as rFSH, but with a markedly pr...
FDA Approves Labeling Change for VYVANSE(R) (lisdexamfetamine dimesylate) CII to Include Supplementary Clinical Data Supporting Efficacy at 13 Hours Postdose in Children Aged 6 to 12 with ADHD
...ontrol in children aged 6 to 12 from the first time point measured (1.5 hours) through 13 hours postdose. VYVANSE is now the first and only oral ADHD stimulant
treatment to have 13-hour postdose efficacy data for pediatric patients included in its product labeling.
"Children with ADHD who still exhibit s...
Shire Delivers Excellent Growth for the Year, With the new Product Portfolio Achieving Sales of $1 Billion
...r the period to September 30, 2008.
VYVANSE - ADHD
VYVANSE was launched in the US in July 2007 as the first and only
once-daily pro-drug stimulant
to treat ADHD.
In April 2008 VYVANSE was approved by the FDA for use in adults and Shire
launched VYVANSE for adult ADHD in June 2008.
Shire Delivers Strong Quarter: Driven by $243m of New Product Sales (+164% YOY Growth). Revenue Guidance Upgrade.
...ced that the Food and Drug Administration ("FDA") had approved the adult indication for VYVANSE, making it the first and only once-daily prodrug stimulant
approved to treat adults with ADHD. Shire launched VYVANSE for adult ADHD in June 2008.
- On May 8, 2008 Shire announced the results of a Phase 3...
Following a Good Start to the Year Shire Reaffirms Full Year 2008 Financial Guidance
... ADHD market. On April 23, Shire
announced that the FDA had approved the adult indication for VYVANSE,
making it the first and only once-daily prodrug stimulant
approved to treat
adults with ADHD. We are well advanced with our pre-launch planning and
expect to launch VYVANSE in the adult market around the midd...
Improved Quantitative Selectivity of Clenbuterol in Human Urine using
High Resolution on the TSQ Quantum Mass Spectrometer
Clenbuterol also has significant anabolic effects and could be used as a
drug of abuse in athletes and livestock for its muscle growth stimulant
properties. It also raises the body temperature and hence facilitates fat
tissue catabolism. Due to Clenbuterol having these anaboli...
Luminol-enhanced Assay for Superoxide Anion (O2 face="Symbol"
superoxide anion activity upon stimulation with 100 ng/ml phorbol 12-myristate
13-acetate (PMA), a protein kinase C activator and a potent stimulant
oxidase. Reaction samples were aliquoted into polystyrene round-bottomed tubes
and placed into a luminometer to measure photon emission. ...
Stimulant in Biological Products
15(S)-15-methyl Prostaglandin F2alpha from Cayman Chemical
Description:... 15(S)-15-methyl PGF2α is a metabolically stable analog of PGF2α. It is a potent uterine stimulant
and abortifacient which can be administered intramuscularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when ...