Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
New work reported in the March issue of Cell Metabolism has provided insight into a key mechanism by which cells limit cholesterol synthesis. The finding suggests a novel approach to the development of cholesterol-lowering drugs that may boost the effect of statins, one of the most prescribed cholesterol inhibitors, according to researchers at the University of Texas Southwestern Medical Center.<...Baby's genes affect mom's cholesterol levels
A group of Belgian researchers has determined that a pregnant woman's ability to metabolize fats is determined not only by her genes but by her baby's genes as well. The details of their findings appear in the November issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal. The researchers, led by Olivier S. Descamps of the Centre de Rech...Cholesterol gets 'thumbs up' for role in digit development
When a new mother counts her newborn's fingers and toes, she probably doesn't realize that cholesterol may be to thank for baby's complete set of 20 digits. Although cholesterol has a bad rap as the sticky, fatty substance responsible for clogging arteries, Vanderbilt University Medical Center researchers recently found that the attachment of cholesterol to an important developmental prot...Nearly half of people who need cholesterol treatment don't get it
Even though treatment for cholesterol disorders can reduce the risk of heart and blood vessel disease by about 30 percent over five years, many at-risk people aren't getting adequate treatment, according to researchers from Wake Forest University School of Medicine and colleagues reporting in Circulation: Journal of the American Heart Association. "Under-treatment of cholesterol disorders...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
Transfer of a gene that produces a mutant form of good cholesterol provides significantly better anti-plaque and anti-inflammation benefits than therapy using the "normal" HDL gene, according to a mouse study conducted by cardiology researchers at Cedars-Sinai Medical Center and reported in the Oct. 3 issue of the Journal of the American College of Cardiology. Apolipoprotein A-I is a natu...Cholesterol Fluorometric (Red) Assay Kit, Amplex Red from Molecular Probes (Invitrogen)
Description:...Goat Anti-Cholesterol Oxidase Polyclonal Antibody, Unconjugated from GeneTex
Description:Cholesterol oxidases exist as both type I and type II oxidases and are implicated in bacterial pathogenesis. In addition, they are important as clinical reagen...Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
It is not high levels of cholesterol but low levels that are making news. Recent reports are indicating that Low levels of Cholesterol maybe linked to depression and violent behavior. A new study shows that men with relatively low cholesterol levels were up to seven times more likely to report symptoms of severe depression. Edward Suarez, PhD from Duke University Medical Center in Durham, N.C....A better way to measure cholesterol
Measuring cholesterol levels is becoming an increasingly important part of a medical check. Generally, it is assumed that high density lipoprotein (HDL, or 'good' cholesterol) levels should be high, and low density lipoprotein (LDL, or 'bad' cholesterol) low. At Johns Hopkins University in the US, researchers believe that it is important to measure non-HDL cholesterol too...Genetics and cholesterol levels
According to a twin study reveals that cholesterol levels are controlled by both genes and dietary factors. People with high blood cholesterol are often advised to go on a low-fat diet - or to take cholesterol-lowering drugs. It's known that reducing fat intake can reduce cholesterol levels. But there is also a genetic condition called familial hypercholesterolaemia (FH) which leads to high chole...Frequent meals can reduce cholesterol
According to a new study eating frequently is linked to lower blood cholesterol concentrations.When people reflect upon a healthy diet, they are normally thinking about what more than how often they have a meal. Some people eat no breakfast, they may skip lunch and then eat everything they can lay their hands on for supper. Others 'graze' through the day, while some people stick to three meals...Eating More Often May Help Lower Cholesterol
A person's cholesterol levels may depend not only on what he or she eats, but also how often. The Researchers found that middle-aged and older adults who ate frequently throughout the day had lower "bad" LDL cholesterol levels compared with those who tended to down one or two large meals per day. This was despite the fact that the frequent eaters, on average, had a higher calorie and fat intake....Direct LDL Cholesterol Reagent
Description:For the direct quantitative determination of low density lipoprotein cholesterol (LDL-C) in human serum or plasma. For in vitro diagnostic use only....HDL-Cholesterol Direct Reagent
Description:Intended for the quantitative in vitro enzymatic determination of JDL-Cholesterol in human serum or plasma. Two point reaction. Wavelength: 600 nm. Linearity: 1 to 150 mg/dL (0.03 mmol/L to 3.89 mmol/L. Two reagents, ready to use liquid....Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal
Medical conventions are challenged every day. Already in the new year, the effectiveness of cold medicine and the gold standard in breast cancer treatment have been challenged. Standards in cholesterol testing are the latest casualty of medical innovation. For years, cholesterol has been measured by a simple panel o...KineMed Presents Data Measuring Changes in Reverse Cholesterol Transport for the First Time
Research Breakthrough Will Aid in Developing Therapies to Preventand Reverse Atherosclerotic Heart Disease EMERYVILLE, Calif., May 10, 2007 /PRNewswire/ -- KineMed, Inc.,a pathway-based drug discovery and development company, announcedtoday the first method for measuring the efflux of cholesterol fromtissues in animals through the pathway known as reverse cholesteroltransport (RCT). RCT i...