FASgen Announces New Diagnostic Research Test for Steatohepatitis
BALTIMORE, FASgen Inc. announced it has successfully expanded the potential use for its serum FAS (fatty acid synthase) ELISA diagnostic research test, FAS-Detect(TM) ELISA for the identification of Non-Alcoholic Steatohepatitis (NASH). The current diagnostic technique for this disease is ...Raptor Pharmaceuticals Corp. and TorreyPines Therapeutics, Inc. Announce Merger Agreement
...e the greatest potential impact. Raptor currently has product candidates in clinical development to treat nephropathic cystinosis , non-alcoholic steatohepatitis ("NASH") , Huntington's Disease ("HD") , and aldehyde dehydrogenase ("ALDH2") deficiency . Raptor's preclinical programs are based upon...Raptor Pharmaceuticals Corp. to Present at 2009 Cystinosis Research Network Family Conference
...e the greatest potential impact. Raptor currently has product candidates in clinical development to treat nephropathic cystinosis , non-alcoholic steatohepatitis ("NASH") , Huntington's Disease ("HD") , and aldehyde dehydrogenase ("ALDH2") deficiency . Raptor's preclinical programs are based up...Raptor Pharmaceuticals to Collaborate with Roche on Therapeutic Delivery Across Blood-Brain Barrier
...an have the greatest potential impact. Raptor currently has product candidates in clinical development to treat nephropathic cystinosis, non-alcoholic steatohepatitis ("NASH"), Huntington's Disease ("HD"), and aldehyde dehydrogenase ("ALDH2") deficiency. Raptor's preclinical programs are based upon bioengineer...Intestinal bacteria associated with non-alcoholic fatty liver disease
...sult of a high fat diet. Importantly, there was no association between either small intestinal bacterial overgrowth or intestinal permeability and steatohepatitis or fibrosis, which argues against a primary role for gut bacteria in the progression of NAFLD to more severe liver disease. "In conclusion," the au...Hyperferritinemia is another surrogate marker of advanced liver disease
... High serum ferritin, being a hallmark of hereditary hemochromatosis , is frequently found in chronic hepatitis C, alcoholic or non-alcoholic steatohepatitis and non-alcoholic fatty liver disease patients . A study in Italy has investigated the link between ferritin and steatosis in a non-obese cohort of no...Is telmisartan effective in treating non-alcoholic steatohepatitis?
...olic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are well-recognized causes of progressive l...uating the effects of telmisartan and valsartan in steatohepatitis that uses paired liver biopsies with NAS evaluatio...nsion, but also can act by preventing and treating steatohepatitis as an end-organ effect of metabolic syndrome. On t...Weight loss improves fatty liver disease, researchers find
... Saint Louis University researchers found that weight loss of at least 9 percent helped patients reverse a type of liver disease known as nonalcoholic steatohepatitis (NASH), a finding that will allow doctors to give patients specific weight-loss goals that are likely to improve their livers. The finding comes from ...Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications
...an have the greatest potential impact. Raptor currently has product candidates in clinical development to treat nephropathic cystinosis, non-alcoholic steatohepatitis ("NASH"), Huntington's Disease ("Huntington's"), and aldehyde dehydrogenase ("ALDH2") deficiency. Raptor's preclinical programs are based upon b...Raptor Pharmaceuticals Appoints Dr. Patrice P. Rioux as Chief Medical Officer
...otential treatment of nephropathic cystinosis ("cystinosis"), non-alcoholic steatohepatitis ("NASH") and Huntington's Disease ("Huntington's"), as well as Convivia(TM)...tes in clinical development to treat nephropathic cystinosis, non-alcoholic steatohepatitis ("NASH"), Huntington's Disease ("Huntington's"), and aldehyde dehydrogenase...Raptor Pharmaceuticals Provides Update on Targeting Platforms
...e Company is currently running clinical trials in patients with aldehyde dehydrogenase ("ALDH2") deficiency, nephropathic cystinosis and non-alcoholic steatohepatitis ("NASH"). Raptor's preclinical programs are based upon bioengineered novel drug candidates and drug-targeting platforms derived from the human recepto...Raptor Pharmaceuticals Enters Collaboration Agreement with UC San Diego in Liver Disease
... Phase 2a clinical trial to evaluate a delayed-release preparation of cysteamine bitartrate ("Cysteamine") in adolescents diagnosed with Non-Alcoholic steatohepatitis ("NASH"). NASH is a progressive form of liver disease that accounts for approximately 10% of newly diagnosed cases of chronic liver disease, and ranks...NAFLD AND NASH Linked to Metabolic Syndrome and Cardiovascular Disease
...ean Association for the Study of the Liver (EASL) further confirm that nonalcoholic fatty liver disease (NAFLD) and its most severe form, nonalcoholic steatohepatitis (NASH), are associated with the metabolic syndrome and pose an increased risk of cardiovascular disease. NAFLD and NASH are significant health probl...Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis
...oncerning diagnosis and prognosis of non-alcoholic steatohepatitis (NASH), allowing the discrimination between normal...sis and NASH predisposed subjects. Non alcoholic steatohepatitis is a progressive disease of the liver of unknown e...his chip also assess the efficacy of non-alcoholic steatohepatitis treatment by determining progression or regression...Obio Pharmaceutical Announces Product Growth Strategy
...Diabetes II, has been granted patents in USA and South Africa. The Company has also successfully patented the AK20 in China, which treats Nonalcoholic steatohepatitis (NASH/ nonalcoholic fatty liver disease). Besides the two patented drugs, Obio has also discovered an antiviral drug candidate -- TG21 that cou...Raptor Pharmaceuticals Closes $10 Million Private Placement
...on. Raptor's initial clinical programs include the treatment of aldehyde dehydrogenase ("ALDH2") deficiency, nephropathic cystinosis and non-alcoholic steatohepatitis ("NASH"). Raptor preclinical programs target cancer, neurodegenerative disorders and infectious diseases. HepTide(TM) is designed to utilize enginee...Raptor Pharmaceuticals Corp. Announces Presentation at 5th International Cystinosis Conference 2008
...on. Raptor's initial clinical programs include the treatment of aldehyde dehydrogenase ("ALDH2") deficiency, nephropathic cystinosis and non-alcoholic steatohepatitis ("NASH"). Raptor preclinical programs target cancer, neurodegenerative disorders and infectious diseases. HepTide(TM) is designed to utilize enginee...Raptor Pharmaceuticals Corp. Enters Agreements to Advance Clinical Pipeline
...ty of California, San Diego ("UCSD") around the use of Cysteamine, and Delayed Release Cysteamine ("DR Cysteamine") for the treatment of Non-alcoholic steatohepatitis ("NASH"). In collaboration with doctors from UCSD School of Medicine, Bennu plans to initiate a Phase 2a clinical study of DR Cysteamine in NASH patie...