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statistically in Medical News

Blood Test Shows Statistically Significant Association With Alzheimer's Disease (AD), May Predict Conversion of Mild Cognitive Impairment to AD

LONDON, BIRMINGHAM, England and VIENNA, July 16 /PRNewswire/ -- Dr. Zsuzsanna Nagy of the University of Birmingham today presented data from a clinical study, funded by Cytox Limited, demonstrating that a simple blood-based biomarker discriminated between patients with Alzheimer's d...

In Landmark Phase III Head-to-Head Study, Prasugrel Statistically Superior to Clopidogrel in Reducing Risk of Heart Attack

Investigational compound reduces risk of major cardiovascular events by 19 percent, significantly improves net clinical benefit despite increased bleeding TOKYO and INDIANAPOLIS, Nov. 4 /PRNewswire-FirstCall/ -- In the pivotal Phase III head-to-head TRITON TIMI...

Link Between Vietnam Service And Prostate Cancer Is Statistically Insignificant

A report that appears in the March 2006 online issue of BMC Public Health focuses on the co-relation between men in the armed forces who served in Vietnam and the incidence of prostate cancer (CaP).// This co-relation exists since a defoliate called Agent Orange has been linked to CaP. However ...

Arizona Pain Specialists Contend Recent Vertebroplasty Studies are Misleading: Studies Actually Show it is Effective at Reducing Pain

...re. Dr. McJunkin said, "Note that patients who received the vertebroplasty procedure had greater reductions in pain, although this was not a statistically significant difference." To demonstrate statistical differences between groups requires that the study have enough patients for the statistic...

Orexigen(R) Therapeutics Announces Second Quarter 2009 Financial Results

...trave patients also showed a 0.6% reduction in HbA1c from baseline, compared to a 0.1% reduction in placebo. This difference of 0.5% is clinically and statistically significant (ITT, p<0.001). Key secondary endpoints met in the COR Phase 3 program included significant improvements in cardiovascular and me...

Transcept Pharmaceuticals to Report Second Quarter 2009 Results

...sing an objective polysomnographic endpoint, Intermezzo (R) demonstrated a statistically significant decrease versus placebo in the time it took patients to return ...p. In the second study, an outpatient trial, Intermezzo (R) demonstrated a statistically significant decrease in Latency to Sleep Onset, a subjective patient report...

Screening May Not Lessen Domestic Violence

...esearchers called intimate partner violence, or IPV. The difference was not statistically significant, the researchers said. Women in the screened group showed mo...n those in the non-screened group, although these differences also were not statistically significant, the researchers said. They found no differences in other healt...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

...nt decrease in median testosterone levels compared with the leuprolide group, which experienced a 65 percent increase in median testosterone levels, a statistically significant result. FIRMAGON was as effective as leuprolide in suppressing testosterone levels from Day 28 to the end of the study (Day 364), with 97...

Heavy drinkers face significantly increased cancer risk

...ry increased their risk of developing oesophageal cancer sevenfold, colon cancer by 80% and even lung cancer by 50%. In all, the researchers found statistically significant relationships between heavy consumption of beer and spririts and six different cancers. Moderate drinking (i.e. less than daily) and wine ...

Advanced targeted therapies effective as first-line treatment for lung cancer

...rlotinib immediately after initial chemotherapy. A statistically significant improvement in overall survival was se...ith vandetanib or chemotherapy with the placebo. A statistically significant difference in PFS was seen (HR = 0.79)...d. Vandetanib treatment was also associated with a statistically significant improvement in symptoms related to the...
statistically in Medical Technology

Isolagen, Inc. Reports Positive Top-line Results from Phase II/III Study of Isolagen Therapy(TM) to Treat Moderate to Severe Acne Scars: Study Meets All Primary Efficacy Endpoints and is Statistically Significant

-Company Provides Update on Cash Position- -Biologics License Application for Wrinkles/Nasolabial Folds Indication Expected To Be Filed Within Two Weeks- EXTON, Pa., March 5 /PRNewswire-FirstCall/ -- Isolagen(TM), Inc. (Amex: ILE ) announced today positive top-line efficacy results ...

PTC Announces Data Showing That PTC124 Causes Statistically Significant Improvements in Chloride Channel Function in Cystic Fibrosis Patients

- PTC124 Highlighted in Multiple Presentations at North American Cystic Fibrosis Conference - SOUTH PLAINFIELD, N.J. and ORLANDO, Fla., Oct. 24 /PRNewswire/ -- PTC Therapeutics, Inc. (PTC) today announced that results from a randomized Phase 2a European study demonstrated that treatment with...

Bionovo's MF101 Shows Statistically Significant Improvement in Sleep Disturbance from Hot Flashes

EMERYVILLE, Calif., Sept. 15 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) today announced that its lead drug candidate, MF101, for menopausal hot flashes, showed improved sleep quality for women in a Phase 2 study completed earlier this year. The Company previously announced that t...

Head-to-Head Study Showed Prasugrel Statistically Superior to Clopidogrel in Reducing Recurrent Cardiovascular Events

New analysis of landmark study showed patients taking prasugrel had lower risk of combined endpoint of recurrent heart attack, stroke or cardiovascular death after first event than those taking clopidogrel TOKYO and INDIANAPOLIS, Aug. 21 /PRNewswire-FirstCall/ -- A new, pre-specified analy...

Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant

Investor Conference Call to be held on Wednesday, August 6, 2008 at 8:00 a.m. EXTON, Pa., Aug. 5 /PRNewswire-FirstCall/ -- Isolagen(TM), Inc. (Amex: ILE) announced today positive top-line efficacy and safety results from two pivotal, Phase III clinical studies ...

Pharmacopeia's First-in-Class Investigational Therapy PS433540 Achieves Statistically Significant Reductions in Blood Pressure in Hypertensive Patients

Single Molecule with Dual Mechanism May Offer Novel Approach to Blood Pressure Management NEW ORLEANS, May 16 /PRNewswire-FirstCall/ -- Pharmacopeia (Nasdaq: PCOP), an innovator in the discovery and development of novel small molecule therapeutics, announced today tha...

Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months

Data Presented Today at the American Heart Association Scientific Sessions 2007 in Orlando, Florida BOCA RATON, Fla., Nov. 7 /PRNewswire-FirstCall/ -- Nabi Biopharmaceuticals (Nasdaq: NABI ) today announced the successful completion of its Phase 2b trial of NicVAX(R) (Ni...

IDM Pharma Announces Updated Phase 3 Mifamurtide (L-MTP-PE) Data Confirms Statistically Superior Overall Survival in Osteosarcoma Patients

IRVINE, Calif., Nov. 1 /PRNewswire-FirstCall/ -- IDM Pharma, Inc. (Nasdaq: IDMI ) today announced the presentation of updated survival data from the Phase 3 mifamurtide (L-MTP-PE) clinical trial (INT-0133). The trial was part of a National Cancer Institute (NCI) funded cooperative group study...

Edwards' Resilient Trial Demonstrates Statistically Superior Results for Treating Peripheral Arterial Disease in the Leg

- Arterial Blockages in the Leg are Estimated to Affect 8 Million Americans - WASHINGTON, Oct. 23 /PRNewswire-FirstCall/ -- Edwards Lifesciences Corporation (NYSE: EW ), a world leader in products and technologies to treat advanced cardiovascular disease, today...

Repros' Proellex Shows Statistically Significant Improvement in Primary Endpoint in Phase 2 Trial in the Treatment of Uterine Fibroids

THE WOODLANDS, Texas--(BUSINESS WIRE)--Apr 3, 2007 - Repros Therapeutics Inc. (NasdaqGM:RPRX) announced final results of a U.S. Phase 2 study of Proellex(TM), an oral drug being developed to relieve symptoms of uterine fibroids. This study suggests that treatment with Proellex results in a statisti...

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statistically in Medical Products

Triage® C. difficile Panel

Features:...ntrols included No need to test separate daily controls Doesnt compromise accuracy for speed Test is fast and definitive Sensitivity for both tests is statistically equivalent to commercially available immunoassays Negative Predictive Value 99.7 percent ...
Company:Biosite
statistically in Medical Definition

Hickam's dictum

...ble of accounting for all relevant evidence. A key reason for using Hickam's dictum as a limiting principle to that of Occam's razor is, it is often statistically more likely that a patient has several common diseases, rather than having a single rarer disease which explains the myriad of their symptoms. Another...

Personalized medicine

... approach: A great number of patients suffer adverse side-effects from prescribed medicines. Deaths (as a consequence of adverse side-effects) are statistically very significant. If a product, such as Vioxx , has to be recalled from the market, the consequences are far reaching and enduring. It costs an...

Surrogate markers

... point. The measurement of surrogate markers provides a way to test the effectiveness of a treatment for a fatal disease without having to wait for a statistically significant number of deaths to occur. the FDA will often accept evidence from clinical trials that show a benefit to surrogate markers instead o...
statistically in Medical Dictionary

Peripheral

...or angioplasty. An analysis of previous studies indicates that among patients with peripheral artery disease, aspirin use is associated with a statistically nonsignificant decrease ... Inhibition of the peripheral chemoreceptors by inhalation of 100% O2 decreased ... Peripheral chemoreceptor activa...

Canker

...form canker sores. ... Canker sores are painful lesions in the mouth. ... what canker sores are, but the exact cause is still unknown. Women statistically suffer from canker sores ... One in five people regularly get bothersome canker sores, which can make eating, drinking and even brushing you...
statistically in Biological News

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

Neurologix, Inc. (OTC Bulletin Board: NRGX) today announced the publication in the June 23 issue of the journal The Lancet of positive results from the first ever gene therapy trial for Parkinson’s disease and the first report of direct gene transfer into a patient’s own brain cells for any adult ...

AGU journal highlights -- Aug. 6, 2009

... simulation is run several times, with prescribed land cover reflecting conditions in 1870 and in 1992. The authors find that in all models, LCC has a statistically significant regional effect on latent heat flux and near-surface temperature. Furthermore, they find that LCC affect temperature only in the region wh...

Health benefits of physical activity more pronounced in women

... or 30 minutes of moderate activity per week) displayed decreased levels of triglycerides and increased levels of the "good" HDL cholesterol. However, statistically significant decreases in the "bad" LDL cholesterol were only observed in women, with particularly strong effects in menopausal women and African-Ameri...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

...istently associated with poorer performance on all eight of the tests; with statistically significant results on tests of semantic memory, working memory, delayed ve...ean body mass, and education, aerobic physical activity continued to show a statistically significant association with cognitive function in non-E4 carriers but not ...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

...s conducted an analysis that controlled for comparable treatment, disparities in tumor prognosis, demographics, and socioeconomic status, and found no statistically significant difference in survival based on race for a number of cancers including lung, colon, lymphoma, leukemia and multiple myeloma. However, Afr...

Army study improves ability to predict drinking water needs

...o the sweat loss predicted by the equation. Once they were able to compare the prediction versus the real sweat rate, they derived specific algorithms statistically so that the predictions would more accurately reflect the observed sweat rates. The study produced two equations. The researchers then cross valida...

The SIB recognizes the next generation of bioinformaticians

...at are distant in the 3-dimensional structure of the protein. The introduced methodology provides a way of describing these interdependencies in a statistically sound and efficient way and thus provides a generalization of currently used models for the characterization of protein sequences. A key feature of th...

Study finds link between individual stress and adolescent obesity

...hickness, trunk fat mass, and percent body fat -- researchers determined that 15 to 45 percent of children were classified as obese. Yet they found no statistically significant relationship between food insecurity and obesity, regardless of which indicator was used. ...

Flow of potassium into cells implicated in schizophrenia

...ggests that schizophrenia stems from complex interactions between multiple genes and environmental factors. Several candidate genes have recently been statistically linked to the illness in large genome-wide association studies. "Our study goes further, spanning discovery of a new gene variant, confirmation o...

Drug prevents seizure progression in model of epilepsy

...y is a neurological disorder marked by abnormal electrical activity in the brain that leads to recurring seizures. A person who has a first seizure is statistically much more likely to have a second, and with each subsequent seizure, the chance of having another seizure grows. A person is often diagnosed with epil...
statistically in Biological Technology

Results From Phase 2 Clinical Study of 6R-BH4 in Peripheral Arterial Disease Not Statistically Significant

NOVATO, Calif., Feb. 3 /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq: BMRN ) today announced results from its Phase 2 multi-center, randomized, double-blind, placebo-controlled clinical study of 6R-BH4 in patients with symptomatic peripheral arterial disease (PAD). There was no...

Sloning and the Kornberg group at Stanford University starting evaluation project regarding the synthesis of a Statistically Randomized Gene Library

Munich, Germany, April 24, 2008 / b3c newswire / - Sloning BioTechnology and Roger Kornberg’s group at Stanford University are working on a project to synthesize a gene mutant library where selected codons are introduced in a statistically expected and controlled ratio at preselected posi...

Arizona Pain Specialists Contend Recent Vertebroplasty Studies are Misleading

...dure. Dr. McJunkin said, "Note that patients who received the vertebroplasty procedure had greater reductions in pain, although this was not a statistically significant difference." To demonstrate statistical differences between groups requires that the study have enough patients for the statistics ...

AutoImmune Inc. Reports 2009 Second Quarter Financial Results

... Status Scale (EDSS), during the two-year Phase III trial in patients with secondary progressive multiple sclerosis (SPMS). In addition, there were no statistically significant differences between dirucotide and placebo on the secondary endpoints of the study. Eli Lilly and BioMS also announced that they would di...

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

...e-breaker session on May 19 at the International Conference of the American Thoracic Society (ATS) in San Diego: CAPACITY 2 demonstrated a statistically significant effect on both the primary endpoint of change in percent predicted FVC at Week 72 and secondary endpoints of progression-free survival and...

Angiotech Pharmaceuticals, Inc. announces financial results for the second quarter ended June 30, 2009

...ng Johnson Johnson, Inc.'s Cypher(R) Stent and Medtronic Inc.'s Endeavor(R) Stent. In the patients with diabetes, the TAXUS Liberte demonstrated a statistically significant lower restenosis rate compared to the Endeavor, which had more than two times the risk of repeat procedures. The JACC article reported tha...

Shire plc: Core Portfolio of Products Delivers 20% Sales Growth

...le additional sections of the NDA as they become available. Results from the first of the three Phase 3 trials were positive, and achieved statistically significant improvements in the primary endpoint. Velaglucerase alfa was also found to be well tolerated with no drug related serious adve...

Ceregene Receives Additional Grant From Michael J. Fox Foundation to Expand Long-Term Testing of CERE-120 Patients

...l group. It was subsequently announced, however, that CERE-120 suggested improvement on several secondary endpoints at 12 months, and at 18 months, a statistically significant treatment effect on the primary endpoint emerged, while several additional secondary endpoints also showed improvement. In contrast, on no...

Poniard Pharmaceuticals Reports Second Quarter 2009 Financial Results and Provides a Corporate Update

...-tumor activity as assessed by PFS and disease control measured by tumor response rate. New data derived by three independent assessments indicated a statistically significant reduction in neurotoxicities with the use of picoplatin in the FOLPI regimen compared with oxaliplatin in the FOLFOX regimen (p<0.0019)...

SENOMYX ANNOUNCES CORPORATE UPDATE AND SECOND QUARTER 2009 FINANCIAL RESULTS

...table progress in its Bitter Blockers Program during the past quarter. Recent taste tests demonstrated that the Company's bitter blockers can provide statistically significant reductions in the bitterness of a variety of product prototypes and food ingredients including tea, cocoa, menthol, Rebaudioside-A, and th...
statistically in Biological Products

ProXPRESS™ 2D Proteomic Imaging System, Basic Package from PerkinElmer

Description:...ore accurate and reproducible detection and quantitation of low abundance proteins on large 2D gels. The systems laser-like high resolution provides a statistically significant number of data points per protein spot. This means more accurate and reliable biological information measurements, which translates into f...
Company:PerkinElmer

ProXPRESS™ 2D Multi-User Applications Package from PerkinElmer

Description:...ore accurate and reproducible detection and quantitation of low abundance proteins on large 2D gels. The systems laser-like high resolution provides a statistically significant number of data points per protein spot. This means more accurate and reliable biological information measurements, which translates into f...
Company:PerkinElmer

ProXPRESS 2D Proteomic Imaging System, Professional Package from PerkinElmer

Description:...ore accurate and reproducible detection and quantitation of low abundance proteins on large 2D gels. The systems laser-like high resolution provides a statistically significant number of data points per protein spot. This means more accurate and reliable biological information measurements, which translates into f...
Company:PerkinElmer
statistically in Biological Definition

Cancer

...tation, randomized trials found no benefit of beta-carotene supplementation in reducing lung cancer incidence and mortality; risk of lung cancer was statistically significantly increased in smokers in the beta-carotene arms of 2 of the trials. Similarly, randomized controlled trials have found no reduction in ri...

Hardy-Weinberg principle

...ut depending which assumption is not met, such deviations may or may not be statistically detectable. Deviations can be caused by the Wahlund effect , inbreeding ...f all three genotypes are known, the can be tested for deviations that are statistically significant . Application to cases of complete dominance Suppose t...

Klinefelter's syndrome

...er identity of people with XXY karyotype is usually male, the number of people with a female gender identity among them seems to be higher than could statistically be expected if those cases were indeed, as the current medical opinion assesses, mere coincidences of people having both gender identity disorder an...
statistically in Biological Dictionary

Regulatory region

...ents; Expt. ... 1, regulatory regions were surveyed in the sequence from bp –1467 to ... The viral regulatory region was found to exert a statistically significant ... Rearrangements in the 1E viral regulatory region were detected in 4 of 60 (6.7 ... applied mainly to gene regulatory regio...

Hyperpolarization

... decreased or caused no apparent change in 5-HTD. ... The hyperpolarization was reversible on removal of CO2/HCO from the perfusion medium. ... A statistically significant hyperpolarization on exposure to CO2/ HCO was ... We have previously reported that electrical stimulation delivered to the ventral ...
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(Date:9/16/2014)... NEW YORK (17 September, 2014)More than $100 trillion ... megatons of annual carbon dioxide (CO2)a 40 percent ... by 2050 if the world expands public transportation, ... new report released by the University of California, ... Policy (ITDP). , Further, an estimated 1.4 ...
(Date:9/16/2014)... -- Each tree species has its own bacterial identity. ... colleagues from other institutions who studied the genetic fingerprints ... a Panamanian island. , "This study demonstrates for the ... and with different ecological strategies possess very different microbial ... Kembel, a former postdoctoral researcher in the UO,s Institute ...
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