Giving Statins to Kids Provokes Debate
Cholesterol-lowering drugs may help young hearts, but long-term use raises concerns
SUNDAY, July 26 (HealthDay News) -- Whether cholesterol-lowering drugs called statins
should be given to children apparently depends on who you ask.
Major health associations in the United States hav...
Many Who Should Use Statins Don't
Survey finds lack of access to medical care a big factor in trend
SATURDAY, April 25 (HealthDay News) -- Nearly half of the Americans who meet the criteria for taking cholesterol-lowering statins
aren't taking the drug, a national survey indicates.
"There is a definite gap between m...
6.5 million more patients might benefit from statins to prevent heart attacks, strokes
Millions more patients could benefit from taking statins, drugs typically used to prevent heart attacks and strokes, than current prescribing guidelines suggest, Johns Hopkins doctors report in a new study.
Doctors have long known that statins
can help prevent subsequent heart attacks and strok...
Dallas Scientists Discover Statins May Falsely Indicate Thyroid Problems
DALLAS, Feb. 19 /PRNewswire-USNewswire/ -- Cholesterol-lowering statins, used by millions of Americans to treat and prevent atherosclerosis, may falsely indicate thyroid problems, according to researchers at Texas Health Presbyterian Hospital Dallas.
Their study, "Radioiodine studies, low ser...
Taking Statins Faithfully Lengthens Life
But experts note finding colored by fact that these folks take better care of themselves generally
MONDAY, Feb. 9 (HealthDay News) -- A massive Israeli study finds that people with high cholesterol levels who faithfully take statins
are less likely to die over four to five years than t...
Got High Cholesterol? Statins Are Not the Only Answer, Says Natural Solutions Magazine
BOULDER, Colo., Feb. 3 /PRNewswire/ -- Eleven million people are currently
lowering their cholesterol with statins
-- and that number continues to climb
as doctors prescribe these pharmaceuticals to those with normal cholesterol as
a preventive measure. But these powerful drugs have many side ...
WomenHeart Urges Women to Talk With Doctors About New Study Showing Statins Prevent Heart Attacks, Deaths
WASHINGTON, Nov. 10 /PRNewswire-USNewswire/ -- WomenHeart today urged
women to talk with their doctors about heart disease risk factors in light
of new research demonstrating the impact of statin therapy
(cholesterol-lowering drugs) on cardiovascular events in women. The study,
Research Shows Why Statins Don't Work for Everyone
A key protein change can lessen the cholesterol-lowering drugs' effectiveness
MONDAY, June 16 (HealthDay News) -- A genetic quirk in the production of one protein helps explain why some people don't get the full cholesterol-lowering benefit of statin drugs, researchers report.
When statins aren't enough: New trial drug points to better management of coronary heart disease
(PHILADELPHIA) Despite widespread use of cholesterol-lowering drugs, a significant number of cardiac patients continue to suffer heart attacks and stroke. Researchers theorize that high levels of an enzyme found in coronary plaques may be to blame, by making plaques more likely to rupture and bl...
iGuard.org Presents New Data on Statins at FDA Workshop Demonstrating How Patient-Reported Information Can Enhance Drug Safety Knowledge
WASHINGTON, May 7 /PRNewswire/ -- Dr. Hugo Stephenson, founder and CEO
of iGuard.org, and specialist in epidemiology and drug safety, today
presented new insight about the cholesterol lowering drugs, referred to as
"statins" to the U.S. Food and Drug Administration (FDA). Although
Statins in Medical Technology
New Study Suggests Cholesterol-Lowering Statins Reduce Severe Asthma Attacks that Result in Hospitalizations and Emergency Room Visits
Patients on corticosteroids are one-third less likely to need emergency room treatment or hospitalization when also taking statin medications
Study is first in a series to examine factors impacting patient response to asthma medications
FRANKLIN LAKES, N.J., March 14 /PRNewswire-FirstCal...
Seniors Can Be Heartened by New Study on Statins
Groundbreaking Research Finds Statins
Cut Risk of Heart Attacks, Deaths
RESTON, Va., Nov. 13 /PRNewswire-USNewswire/ -- Cardiovascular Disease
is the leading cause of death among Americans, costing our healthcare
system hundreds of millions of dollars and causing untold suffering. Now
Cleveland Clinic to Lead First Head-to-Head Comparison of the Two Most Potent Statins
Study Designed to Determine Statin Effects on Regression of Atherosclerosis
CLEVELAND, Jan. 15 /PRNewswire/ -- Cleveland Clinic researchers will
coordinate the first head-to-head comparison of the two most powerful
statin medications. The trial intends to begin enrollment as early as next
Heart Disease Treatment Breakthrough
...e UK from coronary heart
disease. It accounts for one in five deaths in men and one in six deaths in
The four million people who take statins
to help lower their cholesterol
and chances of suffering a heart attack or stroke could benefit from using
Ateronon. The product can be taken alongsid...
New Body of Research Suggests Statin Use Benefits Multiple Areas of Urologic Health
...ed with prostate cancer aggressiveness?
Use of statins
may be associated with more favorable pathological...tin use and development of erectile dysfunction
may provide the added benefit of reducing a man's ...ent of urologic outcomes
The combined use of statins
and non-steroidal anti-inflammatory drugs (NSAIDs)...
New Data for Abbott's TRILIPIX(R) (fenofibric acid) in Combination with Rosuvastatin Calcium Shows Improvement on Key Lipids for Cholesterol Management
...one, TRILIPIX in combination with one of the three most commonly prescribed statins
(atorvastatin, simvastatin or rosuvastatin) or statin alone. The clinical ...tion of the gallbladder or pancreas. Women who are pregnant should not take statins
and should talk with their healthcare provider about TRILIPIX if they are p...
CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis
...ents during the
course of the JUPITER study.
Results from the primary analysis of JUPITER (Justification for the Use
in Primary prevention: an Intervention Trial Evaluating
Rosuvastatin), originally presented in November 2008 at the American Heart
CRESTOR(R) Reduced Risk of Blood Clots in the Veins
...as well tolerated in nearly 9,000 patients during the
course of the JUPITER study.
JUPITER (Justification for the Use of statins
in Primary prevention: an
Intervention Trial Evaluating Rosuvastatin) was a long-term, randomized,
double-blind, placebo-controlled, large-scale study...
Statins Lower Stroke Severity, Improve Recovery
...earchers have shown that patients who were taking statins
before a stroke experienced better outcomes and re...
"We were trying to determine if the daily use of statins
had more of an impact on stroke patients than simp... found it still had quite significant value."
or reductase inhibitors are enzymes that are widel...
Aching Back? Cholesterol Medication Might Help
... Study finds that using statins
may be useful in treatment for degenerative disc disease
LAS VEGAS, F..." says Dr. Yang. "Further studies are needed to determine the potentials of statins
for regeneration and repair of degenerative disc disorders."
In a rel...
Statins in Medical Dictionary
... likely to be caused by autoimmune conditions, rather than directly due to infection It is also a documented side effect of the lipid-lowering drugs statins
and fibrates. InteliHealth - Featuring Harvard Medical School's consumer health information. ... In inclusion body myositis , the muscle also ....
Statins in Biological News
One size does not fit all
...everity reduced indirectly due to the dampening of the immune response. This issue required further investigation, particularly due to the ability of statins
to cross the blood-brain barrier and access the CNS, and the enrichment of cholesterol in the myelin sheath."
The objective of the MNI study was to...
Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants
...z, Ph.D., of NUS for his team's examination of how statins
cholesterol-lowering drugs may restrict growth a..."Our team aims to characterise the interactions of statins
with other proteins known to promote cell death an...rvival, and subsequently explore the potential for statins
to fill the gap in novel strategies for more effec...
Statin therapy ineffective in breast cancer prevention
...atory work in animals showed limited activity when statins
were given to prevent breast cancer, according to ...nducted laboratory work in animals to determine if statins
actually prevent both ER-positive and ER-negative ...sent preclinical studies do not support the use of statins
as general breast cancer preventive agents" said L...
Statins may treat blood vessel disorder that can lead to fatal strokes
...tatin drugs that millions of people take to control high cholesterol.
If the results of a study in mice are confirmed in a pilot trial with people, statins
could provide a safe, inexpensive treatment for cerebral cavernous malformation (CCM), a disorder with no known drug therapy, according to U of U card...
NIH grants Phylonix Phase II SBIR to develop high-throughput in vivo zebrafish assays
...ostly high-profile drug withdrawals due to CYP-related DDIs include the antihistamines terfenadine and astemizole, the antihypertensive mibefradil and statins
such as cerivastatin. A validated, simple, cost-effective in vivo CYP assay will be useful for profiling drug metabolism prior to performing expensiv...
Statin warning for pregnant women
...end that women who are pregnant should stop taking statins
but the advice is based on the knowledge that chol...ital anomalies in children of pregnant women using statins
suggested that the detrimental effects of the drug...s may be restricted to fat-soluble or 'lipophilic' statins
But new research from The University of M...
The genetic heart of the lipids
...d levels, but do not yet improve the prediction of artery or heart disease.
Screening for a person with high lipid levels and early treatment with statins
is one of the major strategies in the prevention of cardiovascular risk in clinical practice while a healthy diet, weight control and physical activit...
Novel bioreactor enhances interleukin-12 production in genetically modified tobacco plants
...ollected the therapeutic proteins grown in the roots, all the remaining material is safely destroyed."
Traditional pharmaceuticals, like aspirin or statins
for lowering cholesterol, are made by synthesizing and combining chemicals in a factory-like production setting. Therapeutic proteins are biologic mol...
A scientific breakthrough on the control of the bad cholesterol
...are used by more than 25 million people worldwide. statins
decrease cholesterol synthesis and increase the nu...k PCSK9 could either be used alone or jointly with statins
and would be highly beneficial to patients in whom statins
do not work or are unable to take this drug.
Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease
...on, vitamin C may be able to reduce CRP as much as statins
have done in other studies," said Block.
Eviden... the study, known as the Jupiter trial, found that statins
reduced cardiovascular mortality and morbidity amo...baseline, levels of CRP were 37 percent lower with statins
compared with a placebo.
"One of the strengths ...
Statins in Biological Technology
AFFiRiS AG: Atherosclerosis Vaccine Development Receives EU Support
these are deemed to be of limited effectiveness despite some notable
CSO Dr. Frank Mattner explains: "Today's therapies with statins
low density lipoprotein cholesterol (LDLc) and reduce its concentration in
the blood. This type of treatment can reduce the likelihood of sever...
Connecticut State Medical Society and Genomas Co-Sponsor Forum on DNA-Guided Medicine and the Path to Personalized Health Care
... Progress Towards DNA-Guided Medicine in Clinical Practice: Case
Studies in Cardiology and Psychiatry. Examples in these two therapeutic
areas include statins
and atypical antipsychotics.
Dr. Ruano commented: "We are privileged to partner with the Connecticut
State Medical Society to convene the physicians...
Old and new therapies combine to tackle atherosclerosis
...ound that stops blood vessel growth.
"We saw that statins
sustain the acute inhibition of blood vessel growt...siology.
Patients with atherosclerosis often take statins
to lower cholesterol. statins
also decrease atherosclerotic plaque progression b...
Abbott and AstraZeneca Expand Relationship to Include Co-Promotion of CRESTOR(R)
... New Drug Application (NDA) to the U.S. Food and Drug
Administration (FDA) in 2009. An NDA for TriLipix for use as monotherapy
and in combination with statins
has been submitted to the FDA and is
currently under review.
"This agreement will allow AstraZeneca to increase share of voice for
CRESTOR among phy...
Anthera Pharmaceuticals Completes $19 Million Financing; Appoints Christopher S. Henney as Chairman
...cited about Anthera and its late-stage anti-inflammatory
platform. We believe the company's lead candidate, Varespladib, has
demonstrated synergy with statins
and represents a potential breakthrough
treatment for people at risk for cardiovascular disease," said Rachel
Leheny, Ph.D., Managing Director of Caxt...
Genzyme Reports Strong First-Quarter Growth
...owering agent being developed primarily for patients at significant cardiovascular risk who are unable to achieve target cholesterol levels with statins
alone or who are intolerant of statins. The product offers an innovative approach to addressing a serious unmet medical need, and Genzyme be...
Genomas Awarded $1.2 Million NIH SBIR Grant to Develop DNA-Guided System for Management of Statin Therapy
entitled "DNA Diagnostic System for Statin Safety and Efficacy," was
awarded by the National Institute of General Medical Sciences (NIGMS).
are the most prescribed drugs in the world. Drugs in this class
include atorvastatin (Lipitor(R)), rosuvastatin (Crestor(R)), and
Synvista Therapeutics Highlights Newly Published Data Demonstrating the Value of Haptoglobin Genotype Testing In People with Diabetes
...s Statin and Antioxidant Therapy to be Superior to statins
in Decreasing Cardiovascular Events in Di...s who had the Hp2-2
phenotype who were also taking statins
were randomized to receive either
natural source V... those taking combination therapy of
Vitamin E and statins
compared with statin treatment alone (1.3 percent
Abbott Receives FDA Approval for SIMCOR(R) (Niaspan(R) / simvastatin), a Novel Combination Medicine for Comprehensive Cholesterol Management
...e. Liver function tests
should be performed on all patients during therapy with Niaspan. Use of
Niaspan with other lipid-altering medications called statins
may increase the
risk of rhabdomyolysis, a rare condition that causes muscles to breakdown.
The most common side effect with Niaspan is flushing of th...
New approach may render disease-causing staph harmless
...e inhibitors developed early on as cholesterol lowering agents might also work on this other pathway, he said. Current cholesterol-lowering drugs like statins
work in a completely different way and would be ineffective.
The researchers began by testing dozens of new compounds for their activity against th...
Statins in Biological Definition
...betes which include kidney failure (requiring dialysis or transplant), blindness, heart disease and limb amputation.
Recent studies show that use of statins
might be needed in primary and secondary prevention of cardiovascular complications and mortality.
Ideal control of hypertension plays a pivotal r...
Statins in Biological Dictionary
...d Parkinson's disease. ... Summaries of the latest research regarding Coenzyme Q10. ... The connection between CHF, coenzyme Q-10 (CoQ- 10) and statins
is discussed ... CoEnzyme Q-10: Introduction. Description/Source: Coenzyme Q10 is a potent ... 1087 Cellular levels of coenzyme Q10 decline i...