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Statin in Medical News

For Treatment of Dyslipidemia, Surveyed Physicians are Increasingly Switching Patients to a More Potent Statin Following the ENHANCE and SEAS Trials

WALTHAM, Mass. , July 8 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, in the treatment of dyslipidemia patients who fail to reach LDL goal, surveyed physicians are increasingly switching patients to...

Genomas Presents Drug-Specific Genetic Determinants of Statin Safety and Efficacy at the XV International Symposium on Atherosclerosis

Data Being Used to Develop DNA-Guided Decision Support for Statin Prescription BOSTON, June 15 /PRNewswire/ -- Genomas, a biomedical company advancing DNA-guided medicine and personalized healthcare, announced its participation at the prestigious XV International Symposium on Atherosclerosis,...

Major statin study reveals several important findings for reducing prostate cancer and disease

ROCHESTER, Minn. -- Statins, drugs widely prescribed to lower cholesterol, may have protective effects on prostate health. This large Mayo Clinic cohort study looked at three different aspects of urological health -- prostate cancer, erectile dysfunction and prostate enlargement. Initial resear...

(Multimedia Version): Abbott Receives FDA Approval for TRILIPIX(TM) (fenofibric acid), First and Only Fibrate Indicated for Use in Combination With a Statin for Cholesterol Management

ABBOTT PARK, Ill., Dec. 15 /PRNewswire-FirstCall/ -- Today, the U.S. Food and Drug Administration (FDA) approved Abbott's TRILIPIX(TM) (fenofibric acid) delayed-release capsules for use along with diet to help lower triglycerides and LDL cholesterol, and to raise HDL cholesterol in patients with...

Abbott Receives FDA Approval for TRILIPIX(TM) (fenofibric acid), First and Only Fibrate Indicated for Use in Combination With a Statin for Cholesterol Management

ABBOTT PARK, Ill., Dec. 15 /PRNewswire-FirstCall/ -- Today, the U.S. Food and Drug Administration (FDA) approved Abbott's TRILIPIX(TM) (fenofibric acid) delayed-release capsules for use along with diet to help lower triglycerides and LDL cholesterol, and to raise HDL cholesterol in patients with...

Heart attack patients who stop statin risk death, say McGill researchers

This release is available in French . Patients discontinuing statin medication following an acute myocardial infarction (AMI) increase their risk of dying over the next year, say researchers at McGill University and the McGill University Health Centre (MUHC). Their study was published in a...

Continued Statin Use Boosts Post-Stroke Outcomes

Interrupting the drugs for even a few days can negatively impact recovery, study finds MONDAY, Aug. 27 (HealthDay News) -- Hospitalized stroke patients who stop taking their cholesterol-lowering statin drugs -- even for a short time -- may increase their long-term risk of death and dis...

FDA Advisers Reject Over-the-Counter Statin

They cite concerns that consumers wouldn't use the cholesterol-lowering drug safely THURSDAY, Dec. 13 (HealthDay News) -- For the third time in seven years, U.S. Food and Drug Administration advisers have voted to deny Merck & Co.'s request to make the cholesterol-lowering drug Mev...

FDA Panel Considering Over-the-Counter Statin

Experts oppose idea on medical and safety grounds THURSDAY, Dec. 13 (HealthDay News) -- For the third time in seven years, a U.S. Food and Drug Administration advisory panel has been asked to recommend making Merck & Co.'s statin drug Mevacor available over the counter. But wi...

FDA Panel to Consider Over-the-Counter Statin

Experts oppose idea on medical and safety grounds THURSDAY, Dec. 13 (HealthDay News) -- For the third time in seven years, a U.S. Food and Drug Administration advisory panel has been asked to recommend making Merck & Co.'s statin drug Mevacor available over the counter. But wi...

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Statin in Medical Technology

New Body of Research Suggests Statin Use Benefits Multiple Areas of Urologic Health

LINTHICUM, Md., April 27 /PRNewswire-USNewswire/ -- Several new studies presented at the American Urological Association's (AUA) 104th Annual Scientific Meeting suggest that the use of statins--commonly prescribed to lower cholesterol--may benefit men with prostate cancer, erectile dysfunction or ...

New Analysis Estimates Numbers of Older U.S. Adults Who May Benefit From Statin Therapy

American Heart Association rapid access journal report: Study highlights: A new analysis estimates more than 11 million older Americans could be newly eligible for statin therapy if findings from the JUPITER trial are adopted into guidelines. That could take the...

CRESTOR Demonstrates Dramatic CV Risk Reduction in a Large Statin Outcomes Study

NEW ORLEANS, Nov. 9 /PRNewswire-FirstCall/ -- New data from the JUPITER study demonstrated that CRESTOR(R) (rosuvastatin calcium) 20 mg significantly reduced major cardiovascular (CV) events (defined in this study as the combined risk of myocardial infarction, stroke, arterial revascularizatio...

New Data Examines the Effect of Adding a Statin to Optimized Treatment for Patients with Advanced Heart Failure

ORLANDO, Fla., Nov. 5 /PRNewswire-FirstCall/ -- New data from the CORONA study presented today at the American Heart Association 2007 Scientific Sessions showed that adding a statin to optimized heart failure treatment did not significantly improve the prognosis for patients with advanced hear...

Survey Finds At-Risk Consumers Interested in OTC Statin

WASHINGTON, Dec. 12 /PRNewswire-USNewswire/ -- According to data released by the National Consumers League today, Americans with unhealthy cholesterol levels would be more likely to consider taking an over-the-counter (OTC) statin option than a prescription (Rx) product, but the likelihood to ...

Study Demonstrates Efficacy of Pitavastatin in Elderly Patients

...ic affairs, Kowa Research Europe. "It may be difficult to choose a suitable statin for elderly patients with primary hypercholesterolemia or combined dyslipid...vastatin has a unique cyclopropyl group on the base structure common to the statin class. Since its 2003 launch in Japan, pitavastatin has accumulated millio...

Essentialis Meets Primary Endpoint in Phase 2b Trial of DCCR for Treatment of Hypertriglyceridemia and is Granted Extensive Patent Coverage in the US

...ns, the effects of DCCR appeared to be additive to statin therapy. Weight and waist circumference reduction,... very high triglycerides and phase 2 protocols for statin combination therapy are currently being finalized ...worldwide. A fixed dose combination product with a statin is under development. About Very High Trigly...

Corgenix AspirinWorks(R) Test Recognized in POLYCAP Study at ACC.09

...elp determine patients' response to aspirin and/or statin therapy. The TIPS trial examined the effect of combinations of aspirin, statin and three blood-pressure-lowering drugs on blood p...endent predictor of risk modifiable by aspirin and statin therapy. The AspirinWorks Test is the only FDA-cle...

New Data for Abbott's TRILIPIX(R) (fenofibric acid) in Combination with Rosuvastatin Calcium Shows Improvement on Key Lipids for Cholesterol Management

...are at high risk of heart disease and are taking a statin medicine to control their LDL cholesterol. TRILIPI...own to prevent heart attacks or stroke more than a statin alone. TRILIPIX is the first and only fibrat...ines recommend the combination of a fibrate with a statin to improve lipid levels. In the clinical ...

CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis

... 40 mg should be used only for those patients not achieving their LDL-C goal with 20 mg. Patients initiating CRESTOR therapy or switching from another statin should begin treatment with CRESTOR at the appropriate starting dose. In the controlled clinical trials database, the most common adverse react...
Statin in Biological News

Intensive statin therapy may partially reverse plaque build-up in arteries

A study presented today at the American College of Cardiology's 55th Annual Scientific Session demonstrates, for the first time, that very intensive cholesterol lowering with a statin drug can regress (partially reverse) the buildup of plaque in the coronary arteries. This finding has never bef...

One size does not fit all

...titute (MNI), McGill University, demonstrates that statin therapy in mice inhibits myelin repair or remyelin... lead investigator in the study. "The mechanism of statin action in these studies was not determined. That is, does statin directly effect myelin and/or the oligodendrocytes...

Calculating gene and protein connections in a Parkinson's disease model

...conserved pathway targeted by cholesterol-lowering statin drugs and another pathway targeted by the immunosu...oxicity, researchers added either rapamycin or the statin lovastatin to yeast model cultures. When the resea... Q10 or CoQ10), which is farther downstream in the statin network and possibly undersynthesized in alpha-syn...

Statin therapy ineffective in breast cancer prevention

... Lovastatin was given at 100 and 500 mg/kg, and it showed no significant preventive -effect similar to atorvastatin. Lubet said the research into statin use and cancer prevention would continue. "There is always the question of whether there will be a subset of breast cancer where this class of agents ...

Statins may treat blood vessel disorder that can lead to fatal strokes

...blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol. If the results of a study in mice are confirmed in a pilot trial with people, stati...

Statin warning for pregnant women

...d growth but the researchers also found that pravastatin the water-soluble statin thought to be potentially compatible for use in pregnancy had the same det...ofessionals should continue to advise women to avoid the use of any type of statin once they plan to start a family or when a pregnancy is suspected or confir...

Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease

...f cholesterol-lowering drugs called statins. They noted that several larger statin trials lowered CRP levels by about 0.2 milligrams per liter; in this latest...n alternative to statins, or as something to be used to delay the time when statin use becomes necessary." ...

MSU researcher studies ties between cholesterol drugs, muscle problems

... all Americans over the age of 50 are prescribed a statin medication, including Lipitor, Crestor and Torvast... 2001, the Food and Drug Administration pulled the statin Baycol off the market after it appeared to be resp...re muscle integrity and function before and during statin treatment. Fifty people half taking high doses of...

Anti-cancer drug prevents, reverses cardiovascular damage in mouse model of premature aging disorder

...ar, in experiments involving a different type of mouse model for progeria, a group of researchers from Spain and France reported that a combination of statin and bisphosphonate drugs slowed development of the visible symptoms of aging and extended life spans in the animals. Both drugs act upon the same biol...

Cholesterol-lowering drugs and the effect on muscle repair and regeneration

... statin-related pain. Both can be exacerbated when statin doses are increased, or physical activity is added...dy may offer another note of caution for high-dose statin patients. Working with primary human satellite cel...le to distinguish between muscle pain related to a statin effect or an effect of aging and therefore adverse...

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Statin in Biological Technology

Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy

REYKJAVIK, Iceland, Nov. 11 /PRNewswire-FirstCall/ -- In a presentation today at the American Heart Association Scientific Sessions 2008, clinicians and researchers from Baylor College of Medicine have presented data from the Atherosclerosis Risk in Communities (ARIC) study, demonstrating that...

Genomas Awarded $1.2 Million NIH SBIR Grant to Develop DNA-Guided System for Management of Statin Therapy

HARTFORD, Conn., March 19 /PRNewswire-FirstCall/ -- Genomas(R), a biomedical company advancing DNA-guided medicine and personalized healthcare, today announced the award of a Fast-Track Phase I-II Small Business Innovation Research (SBIR) Grant totaling $1.2 million. The grant, entitled "DNA D...

Cardiovascular Side Effects of Pioglitazone and Rosiglitazone Linked to Vascular and Energy Pathways by Genomas Clinical Study

...clinical model predictive of drug side effects," said Gualberto Ruano, M.D., Ph.D., President and CEO of Genomas. "Our existing PhyzioType Systems for statin neuro-myopathy and antipsychotic-related diabetes are now being complemented by a third one for TZD-induced cardiovascular side effects for comprehens...

Anthera's Varespladib Demonstrates Significant Anti-Inflammatory Effect and LDL Reduction in Patients With Coronary Heart Disease

...) in patients with cardiovascular disease. Results from the most recent study showed that in patients with coronary heart disease (CHD) currently on statin therapy: -- Varespladib had a significant anti-inflammatory effect as measured by a greater than 20% relative reduction in C-reactive protein -- V...

RVX-208 Exploratory Study Illustrates Early Potential for Alzheimer's Disease

...r the relationship between poor HDL and ApoA-I levels and decreased cognitive function and Alzheimer's disease. Dr. Sparks's investigation of elective statin use and fractionated cholesterol levels in the ADAPT cohort has identified a significant relationship between elevated HDL levels and better performan...

Old and new therapies combine to tackle atherosclerosis

...ts have found that drug-laced nanoparticles plus a statin could stop the growth of tiny blood vessels that f...therosclerotic rabbits that got daily doses of the statin atorvastatin (brand name Lipotor) had no change in plaque angiogenesis measured by MRI. When the statin and the fumagillin nanoparticles were started at t...

Abbott and AstraZeneca Expand Relationship to Include Co-Promotion of CRESTOR(R)

... financial terms were not disclosed. CRESTOR is a once-daily prescription statin medication indicated for use as an adjunct to diet in the treatment of vari...RESTOR once daily. When initiating statin therapy or switching from another statin therapy, the appropriate CRESTOR starting dose should first be utilized, an...

Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic

...trated similar results against the H3N2 and H1N1 viruses. "We are encouraged with these findings," said Dr. Lu. "It is possible that higher doses of statin than those used in this study may result in even greater efficacy. StatC(TM) also appeared to be more effective when administered preventatively." Wit...

Expert Consensus Panel Recommendation for Incorporating Lp-PLA2 Testing into Cardiovascular Disease Risk Assessment Guidelines

...nsideration of increasing the cardiovascular risk category from moderate to high or high to very high risk, directing initiation or intensification of statin therapy to reduce LDL-cholesterol to prevent heart attacks and strokes." The consensus panel also endorsed a simplified framework for traditional Fram...

Synvista Therapeutics Highlights Newly Published Data Demonstrating the Value of Haptoglobin Genotype Testing In People with Diabetes

... Study Shows statin and Antioxidant Therapy to be Superior to Statins ...dy demonstrating that the addition of vitamin E to statin therapy prevented more cardiovascular events (heart attack, stroke and cardiovascular death) than statin therapy alone in patients with Diabetes Mellitus (...
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