Diagnostic tools and innovative therapies improve patient prognosis

...fty-two current or former smokers with an abnormal sputum cytology, at least a 20-year history of smoking a ... DEVICE (LUCED): EARLY DETECTION OF LUNG CANCER IN sputum BASED ON 3D MORPHOLOGY (ABSTRACT # D1.3) Lung ...ous lesions. It has been known for decades that sputum (phlegm) from lung cancer patients frequently cont...

Rare sheep could be key to better diagnostic tests in developing world, says Stanford study

... donors for the microbiology tests necessary to diagnose infectious disease in the developing world. Identifying microbes from a patient's urine or sputum requires growing those microbes in culture dishes filled with gelatinous agar and a small amount of blood. The blood provides nutrients to the growing...

Measurements fail to identify TB patients who could benefit from shorter treatment course

...he two measurements were absence of a cavity (an abscess caused by TB) in the lungs (detected by chest X-ray) and failure to grow TB bacteria from the sputum once drug treatment was started (sputum culture conversion). The Phase III clinical trial involved TB patients in Uganda (Africa), Brazil (S. Americ...

Accelerated Development of New Treatment for Multi Drug-Resistant Tuberculosis: TB Alliance and Tibotec Announce Unique Partnership to Develop TMC207

...udy of 47 patients with MDR-TB, it was found that 48 percent of patients receiving TMC207 in combination with standard treatment converted to negative sputum culture after eight weeks compared with 9 percent of those who received placebo and standard treatment. The safety and efficacy of TMC207 will be furt...

Unique Collaboration Between TB Alliance and Tibotec To Accelerate Tuberculosis Drug Development

...ultidrug-resistant TB (MDR-TB), it was found that 48 percent of patients receiving TMC207 in combination with standard treatment converted to negative sputum culture after eight weeks compared with 9 percent of those who received placebo and standard treatment. The collaboration will maximize the expe...

Two Ways to Tackle Tuberculosis

...etect in a screening program, he said. "Someone may be infected with TB without having an active disease," Painter said. "One standard technology is a sputum smear. You look under a microscope for the disease. Unfortunately, it is not very sensitive. A new technique is to culture a specimen for six to eight...

Sputum in Medical Technology

Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin

...esting is needed." Currently, the most common testing method for TB is sputum microscopy , or the smear test, that has remained largely unchanged in i...ndard method to identify tuberculosis, but it is much more sensitive." sputum microscopy, which often delivers poor sensitivity in patients suffering fro...

Forest Laboratories, Inc. and Laboratorios Almirall, S.A. Provide an Update on the Aclidinium Bromide Clinical Development Program

...entions to cut risks, particularly exposure to tobacco smoke. The most common symptoms of COPD are breathlessness (or a "need for air"), abnormal sputum (a mix of saliva and mucus in the airway), and a chronic cough. Daily activities, such as walking up a short flight of stairs or carrying a suitcase, ...

Nanoemulsion Kills Highly Resistant Bacteria Found in Patients With Cystic Fibrosis

...s with sufficient strength to subdue the bacteria or to penetrate the thick sputum and bacterial biofilms that coat the bacteria. The rising prevalence of dru... also demonstrated bactericidal activity in the presence of cystic fibrosis sputum and against bacterial biofilms, protective coatings that surround bacterial...

Pivotal Data Showed SYMBICORT(R) Improved Lung Function in Adults with COPD

...es compared with formoterol, budesonide and placebo.(1) -- Both SYMBICORT doses significantly (P<.028) improved the sum of Breathlessness, Cough and sputum Scores (BCSS), sleep score, awakening-free nights, and rescue medication use versus placebo.(1) -- Both doses of SYMBICORT were well-tolerated for s...

Mpex Pharmaceuticals Presents New Data on MP-376 in Cystic Fibrosis

...from thickened mucous layers -- Reduced antibacterial activity in CF sputum -- Inconvenient dosing regimens that reduce patient compliance Preclinic...ibiotics. -- Activity in CF sputum: Studies of antibiotic activity in CF sputum showed that levofloxacin retained its full antibacterial activity ...

Landmark COPD Trial UPLIFT(R) Shows SPIRIVA(R) HandiHaler(R) Sustained Lung Function Improvements Over Four Years

... As many as 24 million Americans have impaired lung function,(2) yet fewer than 12.6 million have been diagnosed with COPD.(2) Symptoms include cough, sputum (mucus or phlegm) production, and breathlessness on exertion. Worsening of these symptoms often occurs and can restrict a patient's ability to perform...

Sputum in Medical Products

Eosinophils, Sputum

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Absolute Eosinophils, Sputum

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Misty Ox™ Gas Injection Nebulizer (GIN BABY)™

Description:...oxygen concentration delivery. Heated Aerosol Therapy. Use the optional TurboHeater for airway hydration, mobilization of thick secretions, induced sputum or for rewarming hypothermic patients in the emergency department, post-operative anesthesia care units and neonatal intensive care units....
Company:Vital Signs, Inc.

Acid Fast Control Slides

Description:... These unique Acid Fast Control Slides simulate a clinical sputum smear with appropriate background material. Slides have two wells containing a positive and negative smear. Can be used with Kinyoun (Cat. No. 353), Z...
Company:Scientific Device Laboratory

A.F.B. Stain Control Slides

Description:... Each slide contains an A.F.B. positive staining control of Mycobacterium scrofulaceum ATCC ® 19981 in simulated sputum and an A.F.B. negative staining control of Escherichia coli ATCC ® 25922 in simulated sputum....
Company:Alpha-Tec Systems

Nocardia Stain Control Slides

Description:... Slides contain two wells: a positive control containing Nocardia asteroides ATCC ® 3308 in simulated sputum and a negative control containing Streptomyces albus subsp. albus ATCC ® 3004 in simulated sputum. Nocardia Stain Control Slides should be stained...
Company:Alpha-Tec Systems

Sputum in Medical Dictionary

Sputum

Sputum is matter that is expectorated from the respiratory tract, such as mucus or phlegm, mixed with saliva, which can then be spat from the mouth. It is usually associated with air passages in diseased lungs, bronchi, or upper respiratory tract. It can be found to... sputum n. , pl. -...

Purulent

...cytology and mycobacterial ... 3. Purulent sputum is defined as secretions from the lungs, bronchi,... sputum. ... single notation of either purulent sputum or change in ... Patient is in ICU or is bein... in association with the production of purulent sputum ... All my custom Homeopathic remedies are SA...

Pneumocystis Carinii

... has not been shown to infect other animals, while other... However, Pneumocystis carinii can cause a lung infection in in people with a ... sputum induction (to detect Pneumocystis carinii ) Treatment Return to top ... LUNG PARASITES. INCERTAE SEDIS. PNEUMOCYSTIS JIROVECI (P. CARINII ) p...

Phlegm

.... Conditions causing symptom Phlegm symptoms including possible medical causes, diseases, disorders, ... Symptoms related to Phlegm symptoms: sputum symptoms (14) ... Describes the causes, meaning and cures of phlegm and how to get rid of it. ... Yet phlegm is produced as part of our defen...

Inhalation anthrax

...respiratory anthrax is an infectious disease caused by inhaling ... If inhalation anthrax is suspected, a chest X-ray, blood cultures, and sputum ... Inhalation Anthrax ( Anthrax - Inhalation ) information center covers causes, prevention, symptoms, diagnosis, treatment, incidence, ri...

Hemoptysis

...tion (coughing up) of blood or of blood-stained sputum from the bronchi, larynx, trachea, or lungs . ...moptysis is the coughing up of blood or bloody sputum from the lungs ... Massive hemoptysis has...moptysis is the coughing up of blood or bloody sputum from the respiratory tract. ... Hemoptysis is...

Sputum in Biological News

Nanoemulsion potent against superbugs that kill cystic fibrosis patients

...barricades in the lungs: biofilms that bacteria form around them, and thick sputum present in the lungs of patients with cystic fibrosis. Research details...ditions in a patient's body. Antibiotics often can't penetrate biofilms and sputum unless given at high doses with unacceptable side effects. "We saw, not ...

In lung cancer, silencing one crucial gene disrupts normal functioning of genome

...the findings contribute to the basic understanding of lung cancer development, they may also be useful in designing a "methylation signature" blood or sputum biomarker test to identify individuals who are at risk of developing the disease, the researchers say. "That may prove particularly beneficial in diag...

American Chemical Society's Weekly PressPac -- Dec. 3, 2008

...n of the first potential "biomarker" that could be used in development of a sputum test for early detection of chronic obstructive pulmonary disease (COPD). ...ed levels of SP-A. The scientists also found elevated levels of SP-A in the sputum samples of COPD patients. "This suggests that SP-A might represent a helpfu...

Space technology harnessed to search out TB

...B in resource-poor settings relies mainly on the use of smear microscopy of sputum samples, a very labour-intensive process with low sensitivity. Now, res...an adapt Rosetta's technology to develop a GC-MS capable of detecting TB in sputum with greater sensitivity than smear microscopy and significantly quicker th...

Study finds environmental tests help predict hospital-acquired Legionnaires' disease risk

...-year period. When cases of Legionnaires were identified, patient urine and sputum samples from 12 of the hospitals were tested to determine classification of...were among the 633 patients with hospital-acquired pneumonia whose urine or sputum samples were tested for Legionella bacteria. All were traced to hospitals w...

HIV/AIDS linked to extensively drug resistant TB

...ug resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis in a hospital in KwaZulu Natal. Between January 2005 and March 2006, sputum samples from 1,539 patients were screened. MDR TB was found in 221 patients and of those, 53 had XDR TB. Those patients with XDR who were tested for H...

Sputum in Biological Technology

New Research Shows Many Patients with Persistent Cough and Sputum Actually had Airway Obstruction Consistent with COPD

- More than one quarter (26%) of primary care patients 40 years of age and older with a smoking history and symptoms of chronic bronchitis had airflow obstruction consistent with a diagnosis of COPD - Percentages were greater with increasing patient age and smoking history PHILADELP...

Phase 3 Cystic Fibrosis Trial Results Presented at European Conference

...ity of the lung, pulmonary exacerbations and antibiotic use. Safety evaluation included the incidence of adverse events and the microbiology of sputum samples. Clinical Results -- There was a clinically meaningful change from baseline (119mL) and placebo (93mL) at week 26 with Bron...

Cepheid Announces Symposium Speakers and Program Highlights for 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

... Xpert MTB/RIF not only detects the presence of TB organism directly from sputum in less than two hours, but also identifies whether the strain is resistant...apid detection of Mycobacterium tuberculosis and rifampicin-resistance from sputum samples with an easy-to-use PCR test system with near-patient capability ...

Cepheid Announces New Diagnostic Technology to Aid World Efforts in Halting the Spread of Mycobacterium Tuberculosis (TB)

... Africa and Southeast Asia due to the close connection between HIV and TB. sputum microscopy, which often delivers poor sensitivity in patients suffering fro...most needed." Currently, the most common testing method for TB is the sputum microscopy, or smear test, that has remained largely unchanged in its so...

MedImmune Advances Asthma Program With Start of Phase 2 Clinical Trial for Antibody Targeting IL-5 Receptor

...development. Published literature suggests that reduction of eosinophils in sputum was associated with better asthma control and increases in sputum eosinophilia were associated with exacerbations of asthma. The antibody is ...

The Bill & Melinda Gates Foundation, BIO, and Bio Ventures for Global Health Invite Proteome Systems' CEO to Speak on TB Diagnostics Solutions At Partnering for Global Health Forum, Washington D.C.

... and screening tests to distinguish active TB from other conditions with similar symptoms. The PXL test aims to allow direct detection of active TB in sputum and/or blood in a cost effective point of care format for rapid diagnosis," Dr Harry said. About Proteome Systems Proteome Systems Limited [ASX: P...

Sputum in Biological Products

Stat-Pack Sputolysin Reagent from Caldon Biotech, Inc.

Description:...e concentration of Dithiothreitol (DTT) solution in phosphate buffer (pH 7.0). Dilute contents in one vial (10- fold) to 100 ml. For use in liquefying sputum samples....
Company:Caldon Biotech, Inc.

Angle Rotor with 323 Sealed Buckets, 4 50 ml from Thermo Scientific

Description:... 45° Fixed Angle Rotor for use in the IEC Centra CL2, Centra CL3CL3R, and Centra-MP4/MP4R. Perfect for rapid concentration of sputum samples and other difficult to separate infectious samples. Provides individual aerosol containment. Complete with rotor and 4 sealed shields....
Company:Thermo Scientific

Sputum in Biological Dictionary

Trematode

...Joint WHO/FAO Workshop on Foodborne Trematode Infections in Asia, which was held ... trematode eggs frequently cannot be detected in the stools or sputum of ... Advances in Trematode Biology. Bernard Fried. CRC Press ... Advances in Trematode Biology presents a thorough treatment of modern ... ...

Cytology

...ealth Care Policy and Research - AHCPR), 12 ... sputum cytology examines a sample of sputum (mucus) under a microscope to ... sputum cytology may be done to help detect certain nonc...