A new indicator for esophageal varix in alcoholic disease

...currence of esophageal varices. Abdominal ultrasonography (US) was performed on 444 patients suffering from alcoholism. The alcoholic patients with splenomegaly and/or withering of the right lobe of the liver were defined as severe alcoholic disease patients (SAD) and participated as the study subjects. The SA...

Medifacts Systems, Inc. Grants Exclusive License for Genetic Test Patent to Mayo Clinic

... poor oxygen delivery to tissues. The disease may first be noticed in childhood or in early adult life, when microcytic hypochromic anemia and splenomegaly are noted. -- If all four loci are affected, the fetus cannot live once outside the uterus and may not survive gestation. This is called hydrops ...

Splenomegaly in Medical Technology

Shire Reports Positive Results From First of Three Phase III Trials of velaglucerase alfa for Type 1 Gaucher Disease and Provides Important Updates on Interactions With FDA

...hey presented with disease-related anemia and had at least one of the following clinical manifestations of Gaucher disease: thrombocytopenia, moderate splenomegaly or a readily palpable enlarged liver. Patients were randomized to receive velaglucerase alfa at either 45 U/ kg or 60 U/ kg for a duration of 12 month...

TargeGen Announces Successful Completion of Patient Enrollment in Clinical Trial of JAK2 Inhibitor TG101348 in Myelofibrosis Patients and Scheduled Presentation of Preliminary Trial Data at EHA Conference in Berlin

...udy. Preliminary trial data presented at the 2008 ASH conference indicated that the drug was well tolerated and exhibited dose-dependant reductions of splenomegaly and leukocytosis. Updated clinical data pertaining to this trial are scheduled for presentation at the European Hematology Association (EHA) conferenc...

Splenomegaly in Medical Dictionary

Splenomegaly

Splenomegaly is an enlargement of the spleen, which usually lies in the left upper quadrant (LUQ) of the human abdomen. It is one of the four cardinal signs of hypersplenism, the other three being cytopenia(s), normal or... Enlarged spleen — Comprehensive overview covers symptoms, causes,...

Tropical sprue

...ts of ... Overview: Tropical sprue (TS) is a syndrome characterized by acute or chronic ... Celiac Sprue (Gastroenterology) Tropical splenomegaly Syndrome (Pediatrics: ... tropical sprue ( ′träpəkəl ′ sprü ) ( medicine ) A malabsorption disease found in tropical and subtropical cl...

Spleen

... it plays no part ... asplenia n. Congenital absence of the spleen . asple ' nic adj. ... Acquired asplenia/hyposplenism · Wandering spleen · splenomegaly (Banti's syndrome) ... Cincinnati Children's provides information about spleen injuries, including symptoms, causes, treatment, after care and m...

Hypersplenism

... splenomegaly is an enlargement of the spleen, which usually lie...enism Definition Hypersplenism is a type of splenomegaly n. , pl. -lies . Enlargement of the spleen. ... PatientPlus splenomegaly and hypersplenism . Medical dictionary. 11-141b. ...

Hepatomegaly

...aly may include: Alcohol use Congestive heart failure ... Information about hepatomegaly in the free online English ... No hepatomegaly or splenomegaly was noted, and the patient was afebrile. ... hepatomegaly n. Abnormal enlargement of the liver. ... Findings are Hepatomegaly with diffuse h...

Splenomegaly in Biological News

Avoiding Spleen Removal for Cooley's Anemia SufferersAvoiding spleen removal for Cooley's anemia suf

...ent transfusions. However, hemoglobin (Hb) levels often decrease over time, splenomegaly appears, and progressive iron overload occurs from increased gastrointestin...y, affected persons suffer from anemia, which is exacerbated by progressive splenomegaly and an increase in plasma volume as a result of shunting through the expand...