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Spasticity in Medical News

Webinar on June 25 to Focus on Opportunity for Treating Chronic Pain, Migraine and Muscle Spasticity Through Inhibition of Neurotransmitter Glutamate

TorreyPines Therapeutics' CEO Neil Kurtz, M.D., to Moderate Discussion Following Presentations by Tony Yaksh, Ph.D.; Jerome Goldstein, M.D.; and Alan J. Tuchman, M.D. LA JOLLA, Calif., June 20 /PRNewswire/ -- A Webinar hosted by TorreyPines Therapeutics, Inc. (Nasdaq:...

Pain and Intensity Of Post-stroke Spasticity Decreased by Botox Treatment

Final results from a multi-center study shows that repeated treatments of botulinum toxin type A over one year is well tolerated and results in a significant decrease in spasticity, pain frequency and average pain intensity in upper limbs following stroke, according to research from a neurologist ...

Toxin injections support stroke associated spasticity

Researchers have found that injections of botulinum toxin eases hand spasticity among stroke survivors. Spasticity in the limbs is a common after effect of stroke, and it causes much disability,// because it interferes with activities like getting dressed and eating. Previous research has shown tha...

Cerebral Palsy Improves After Bone Marrow Stem Cell Procedure

...tions of stem cells, is pleased to report the results of a 16 year old girl who suffered from cerebral palsy. The patient had right side paralysis and spasticity since birth. The procedure consisted of removing 300 milliliters of bone marrow from her hip and giving it back to her intravenously. Five hours after...

FDA Mandates New Warnings for Botox

...ious type of label warning, the U.S. Food and Drug Administration announced Thursday. Most cases involved children given the drug to control muscle spasticity associated with cerebral palsy and adults using it to treat muscle spasticity, migraines and cervical dystonia. "The hospitalizations are very few...

New Analyses from 16-Year Follow-up Trial with Betaseron(R) Demonstrated that Early and Sustained Treatment of Multiple Sclerosis Patients Enrolled in the Trial Affected Their Long-term Outcomes

...ness, dimness of vision in one or both eyes, weakness in one or more extremities, numbness and tingling in the face, arms, legs and trunk of the body, spasticity (muscle stiffness), dizziness, double vision, slurred speech and loss of bladder control. ABOUT BAYER HEALTHCARE PHARMACEUTICALS INC. Baye...

JumpStart and Case Technology Ventures Invest in Neuros Medical

...erapies for unmet needs to patients worldwide. The Company's platform technology, Nerve Block, provides patients with elimination of chronic pain and spasticity in a variety of applications including neuroma/residual limb pain with potential applications in cancer pain, diabetic neuropathy, cerebral palsy, mul...

MRI scans can predict effects of MS flare-ups on optic nerve

...erative disorder that can present with an extremely broad variety of symptoms that range from vision loss and other sensory damage to muscle weakness, spasticity or paralysis to depression, sleep loss or incontinence. MS affects an estimated 500,000 Americans. "We see this as part of a battery of tests we ho...

Video: Paralyzed From the Chest Down, Triathlete Takes Second in the Handcycle Division of the Ford Ironman World Championship

...ing use of his lower body, he suffered from severe spasticity and painful muscle spasms in his back and legs. H... Following the surgery, Jason's spasms and spasticity decreased drastically. His leg and back muscles re... Talk to your doctor. To learn more about spasticity caused by spinal cord injury and ITB Therapy, plea...

TorreyPines Therapeutics Announces Management Change and Second Quarter 2008 Financial Results

...lop versatile product candidates, each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates: two ionotropic glutamate receptor antag...
Spasticity in Medical Technology

TorreyPines Therapeutics to Host Webinar at 11 a.m. EDT Today on the Opportunity for Treating Chronic Pain, Migraine and Muscle Spasticity Through Inhibition of Neurotransmitter Glutamate

TorreyPines Therapeutics' CEO Neil Kurtz, M.D., to Moderate Discussion Following Presentations by Tony Yaksh, Ph.D.; Jerome Goldstein, M.D.; and Alan J. Tuchman, M.D. LA JOLLA, Calif., June 25 /PRNewswire/ -- A Webinar hosted by TorreyPines Therapeutics, Inc. (Nasdaq:...

Tezampanel, TorreyPines Therapeutics' Lead Compound, Reduced Muscle Spasticity and Rigidity in Preclinical Study Conducted at University of California, San Diego

Data Suggest Potential for Treating Motor System Disorders LA JOLLA, Calif., Oct. 17 /PRNewswire/-- Tezampanel, a novel small molecule currently in clinical development by TorreyPines Therapeutics, Inc. (Nasdaq: TPTX ) for the treatment of acute migraine headache, was shown in an indep...

Merz Pharmaceuticals Announce Three Studies of NT-201 - (Botulinum neurotoxin type A Free From Complexing Proteins)

...n; botulinum neurotoxin type A free from complexing proteins) in upper limb spasticity patients. Eric Pappert, M.D., Vice President of Medical Affairs, Merz...tulinum neurotoxin free from complexing proteins) in upper limb post-stroke spasticity patients authored by P. Kanovsky for the NT 201 Study Group, I. Sassin, G. ...

Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting

...sm and cervical dystonia -- one placebo-controlled spasticity trial and one upper limb spasticity trial -- were presented at the Movement Disorder S... to potentially aid focal dystonia and post-stroke spasticity sufferers," said Eric Pappert, M.D., Vice Presiden...

Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients

...ean efficacy and safety data in patients with focal dystonia and upper limb spasticity will be presented at the American Academy of Neurology's (AAN) 61st annual... symptomatic management of blepharospasm, cervical dystonia and post-stroke spasticity of the upper limb. Through advanced manufacturing processes, NT-201 combin...

TorreyPines Therapeutics Muscarinic Agonist NGX267 Meets Primary Endpoint in a Phase II Clinical Trial in Patients with Xerostomia

...elop versatile product candidates each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates, two ionotropic glutamate receptor anta...

Five-Year Data Confirm That Early Treatment with Betaseron(R) at First Sign of Disease Can Delay Progression to MS

...ness, dimness of vision in one or both eyes, weakness in one or more extremities, numbness and tingling in the face, arms, legs and trunk of the body, spasticity (muscle stiffness), dizziness, double vision, slurred speech and loss of bladder control. About Bayer HealthCare Pharmaceuticals Inc. Bayer Health...

Data Presented at American Headache Society's Annual Scientific Meeting Show Primary Endpoint Met as Well as Improvement on Important Secondary Endpoints in Phase IIb Acute Migraine Trial of TorreyPines Therapeutics' Tezampanel

...e and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently ...f chronic pain such as neuropathic pain and fibromyalgia, as well as muscle spasticity and rigidity, thrombosis and epilepsy. Such statements are subject to numer...

TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel

...s of chronic pain such as neuropathic pain, muscle spasticity and rigidity, thrombosis, epilepsy, Parkinson's di...d disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. ...s of chronic pain such as neuropathic pain, muscle spasticity and rigidity, thrombosis, epilepsy, Parkinson's di...

TorreyPines Therapeutics Announces Strategic Plan with Focus on Clinical Development Activities to Maximize Value of Versatile Lead Compounds

... Initiate a Phase II trial of tezampanel in muscle spasticity and rigidity secondary to spinal cord trau...ases and disorders, including chronic pain, muscle spasticity and rigidity, cognitive disorders and xerostomia, ...ic pain indications, and as a treatment for muscle spasticity and rigidity, the potential for NGX426 as a treatm...
Spasticity in Medical Products

Comfy™ Elbow and Hand Spasticity Orthosis

Description: Comfy™ Elbow and Hand Spasticity Orthosis decreases the effects of flexion synergy on the upper extremity post-stroke. Treat elbow, forearm, wrist simultaneously. First, apply elbow component to the patient and adjust to meet available passive ROM. Next, attach pronation/supination bar to elb...
Company:AliMed, Inc.
Spasticity in Medical Dictionary

Spasticity

Spasticity or muscular hypertonicity is a disorder of the central nervous system (CNS) in which certain muscles continually receive a message to tighten and contract. The nerves leading to those muscles, unable to regulate themselves, permanently and continually... Spas·tic·i·ty n. 1. A sta...

Syringomyelia

...t. Join Our ... syringomyelia n. A chronic disease of the spinal cord characterized by the presence of fluid-filled cavities and leading to spasticity and sensory Syringomyelia Facts plus the Latest News on Syringomyelia Treatments - HealthNewsflash ... Syringomyelia (sear-IN-go-my-EEL-ya)...

Paralysis

...: Causes and symptoms Diagnosis Treatment Prognosis Prevention Resources Paralysis Definition Paralysis is defined as complete Paralysis ... spasticity and Paralysis (National Stroke Association) ... Genetics Home Reference: Hyperkalemic periodic paralysis (National Library of Medicine) ... ... ...

Opisthotonos

... opisthotonos , from Greek roots, opistho meaning "behind" and tonos meaning "tension", is a state of a severe hyperextension and spasticity in which an individual's head, neck and spinal column enter into a complete "bridging" or "arching" position. This... Op...
Spasticity in Biological News

Treating chronic pain, migraine & muscle spasticity through inhibition of neurotransmitter glutamate

LA JOLLA, CA, June 20, 2008 A Webinar hosted by TorreyPines Therapeutics, Inc. (NASDAQ: TPTX) at 11 a.m. EDT on June 25 will bring together industry experts to discuss the opportunity of treating chronic pain, migraine and muscle spasticity through the inhibition of the neurotransmitter glutamat...

Motor neuron disease and toxic substances: Possible link?

.... Fink examined members of two families who had progressive weakness and spasticity (tightness) in their legs, as well as muscle atrophy in their hands, shins ...It begins in childhood and progresses slowly, with symptoms of weakness and spasticity in the legs and muscle atrophy in the hands and lower legs. Next, Fink a...

Human stem cell treatment restores motor function in paralyzed rats

...spinal inhibitory neurons, leading to irreversible spasticity and rigidity, or loss of muscle control, in the lo...ls. Current treatment for debilitating muscle spasticity is continuous systemic or spinal drug treatments u...h spinal ischemic injury who suffer from resulting spasticity and rigidity,” said Marsala. ...
Spasticity in Biological Technology

CeNeRx BioPharma Awarded New Patent for its Innovative Compounds That Selectively Target Peripheral Cannabinoid Receptors

...and CB2 cannabinoid receptors. The company is initially pursuing cannabinoid agonists for the treatment of pain (peripheral neuropathy), glaucoma and spasticity and has already demonstrated encouraging proof-of-concept results in a number of well-accepted preclinical models. "Our cannabinoid series of co...

GSK and XenoPort Resubmit New Drug Application for Solzira(TM) in Restless Legs Syndrome

...Port's product candidates are also being studied for the potential treatment of gastroesophageal reflux disease, migraine headaches, neuropathic pain, spasticity related to spinal cord injury, acute back spasms and Parkinson's disease. To learn more about XenoPort, please visit the Web site at www.XenoPort.co...

TorreyPines Therapeutics Receives NASDAQ Deficiency Notice

...lop versatile product candidates, each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates: two ionotropic glutamate receptor antag...

TorreyPines Therapeutics to Present Tezampanel Phase IIb Clinical Data for Acute Migraine at 50th Annual Scientific Meeting of the American Headache Society

...elop versatile product candidates each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates: two ionotropic glutamate receptor antag...

TorreyPines Therapeutics to Host First Quarter 2008 Results Conference Call and Webcast

...elop versatile product candidates each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates: two ionotropic glutamate receptor antag...

TorreyPines Therapeutics Reports Fourth Quarter and Full Year 2007 Financial Results and Highlights

...be effective in reversing or preventing muscle spasticity and rigidity of spinal ischemia. TorreyPines ...rial of tezampanel for the treatment of muscle spasticity and rigidity secondary to spinal cord trauma d...d disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. ...

TorreyPines Therapeutics Initiates Phase II Study of Muscarinic Agonist NGX267 for Treatment of Xerostomia

...elop versatile product candidates each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates, two ionotropic glutamate receptor antag...

TorreyPines Therapeutics to Present at Susquehanna Financial Group's Second Annual SIGnificant Options in Healthcare Conference

...loping versatile product candidates, each potentially capable of treating a number of different diseases and disorders, including chronic pain, muscle spasticity and rigidity, cognitive disorders and xerostomia, or dry mouth. Further information is available at http://www.torreypinestherapeutics.com . Com...
Spasticity in Biological Definition

Muscle

...scles. Disease Symptoms of muscle disease may include weakness or spasticity /rigidity, myoclonus (twitching) and myalgia (muscle pain). Diagnostic ...their nervous control. In general, problems with nervous control can cause spasticity or paralysis , depending on the location and nature of the problem. A lar...
Spasticity in Biological Dictionary

Motor neuron

... ... Degenerating motor neurons contain ubiquitin-positive neuronal and glial ... This causes motor neuron loss by an unkown mechanism. ... spasticity is found with upper motor neuron injuries and manifests as a marked ... Upper Motor Neuron Damage (UMN) ... 10-3. Lower motor neuron damag...
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