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Somatic in Medical News

Is somatic hypersensitivity a predictor of irritable bowel syndrome?

Although visceral hypersensitivity is considered a hallmark feature of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. Several investigators have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others have reported si...

Converting adult somatic cells to pluripotent stem cells using a single virus

(Boston) -- A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process. The result is a powerfu...

Somanetics Reports Second Quarter Results and Extension of Exclusive Distribution Agreement With Covidien

...ng the INVOS System have been shown to improve outcomes after surgery. In neonates, infants and children, cerebral and somatic rSO2 provide noninvasive indications of oxygen changes in the cerebral and peripheral circulatory systems and may provide an early indication of oxyge...

New interdisciplinary volume focuses on advances in stem cell research

... 5-8 chapters on a specific topic: Germ Cells and Totipotency, Niches and Asymmetry, Embryonic Development and Multipotent Progenitors, Reprogramming somatic Cells, Gene Expression and Transcriptional Networks, Epigenetics, Adult Stem Cells, Neural Stem Cells and Brain Tumors, Stem Cells and Cancer, and Ren...

World first: Chinese scientists create pig stem cells

...embryonic stem cells, are capable of developing into any type of cell in the body. It is the first time in the world that this has been achieved using somatic cells (cells that are not sperm or egg cells) from any animal with hooves (known as ungulates). The implications of this achievement are far-reach...

25 Clinical Abstracts at National Conference Spotlight Clinical Utility of Somanetics INVOS System in Neonates

... required. Another study examined four drugs, commonly used in the NICU to manage a range of severe conditions, and their effect on cerebral and somatic (e.g., abdomen, kidney area, muscle) regional oxygen saturation (rSO2). The INVOS System showed that each drug produced distinct medication-specific c...
Somatic in Medical Technology

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

...ssays test colorectal cancer to determine whether a particular therapeutic strategy should be used by oncologists. Most colorectal cancer is caused by somatic mutations and is not hereditary. Mutations in the oncogene KRAS are seen in over 40 percent of sporadic colorectal cancers. While several laboratori...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...onal/page11 . Accessed May 2009. Carvajal RD, et al. A phase II study of Imatinib mesylate (IM) for patients with advanced melanoma harboring somatic alterations of KIT. Abstract # 9001. American Society of Clinical Oncology 2009 Annual Meeting, Orlando, FL. Hainsworth J et al. Phase II tri...

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

...to normal human embryos. The paper is available free online at www.liebertpub.com/clo . Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate personalized stem cells to repair the body without fear of tissue rejecti...

Research Teams at J. Craig Venter Institute and Ludwig Institute for Cancer Research Uncover New Chromosomal Alterations in Cancer Using Transcriptome Sequencing Approach

...sequencing coverage this approach could be a powerful and efficient way to discover all events associated with expressed genes including gene fusions, somatic mutations and alternative trans-splicing that lead to the development of cancer. Robert Strausberg, Ph.D., Deputy Director of the JCVI and leade...

European CHMP Issues Positive Opinion on Cymbalta for the Treatment of Generalised Anxiety Disorder

... Results from a Placebo- and Active-Controlled Trial. Int Clin Psychopharmacol 2007: 22(3):167-74. (4) Nicolini H, et al. Improvement of psychic and somatic symptoms in adult patients with generalized anxiety disorder: Examination from a duloxetine, venlafaxine extended-release, and placebo-controlled stud...

GeneGo is Awarded NCI Grant for Development of Systems Biology Platform for Integrative Data Analysis in Cancer

...te and a consultant on the grant. "Another focus will be on the development of pathway-based tools for integration of different types of OMICs data -- somatic mutations, high copy number genes, epigenetics, gene expression, proteomics and metabolomics." About GeneGo GeneGo develops systems biology techno...
Somatic in Medical Products

Total T4 RIA Test

Description:...throcytes [1,2]. Less than 0.1% of the total T4 circulates in a free or unbound form. T4 binds to specific cell receptors and has diverse cellular and somatic effects. Measurement of total serum T4 levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid hormones....
Company:Diagnostic Systems Laboratories, Inc.

Total T4 EIA Test

Description:...throcytes [1,2]. Less than 0.1% of the total T4 circulates in a free or unbound form. T4 binds to specific cell receptors and has diverse cellular and somatic effects. Measurement of total serum T4 levels is a standard and well-validated test of thyroid gland function [3]. Physiology of thyroid hormones....
Company:Diagnostic Systems Laboratories, Inc.
Somatic in Medical Definition

Medicine

... with systemic diseases of adults, i.e. those diseases that affect the body as a whole (restrictive, current meaning), or with all adult non-operative somatic medicine (traditional, inclusive meaning), thus excluding pediatrics, surgery, gynaecology and obstetrics, and psychiatry. There are several subdiscip...

Somatic dysfunction

... In osteopathic medicine , somatic dysfunction is the impaired or altered function o... 4 Sources Diagnosis somatic dysfunction is diagnosed by physical examination. ... Significance The physical manifestation of somatic dysfunction is frequently associated reciprocally ...
Somatic in Medical Dictionary

Trisomy

...ue to the presence of an extra #18 chromosome. ... trisomy n. , pl. -mies . The condition of having three copies of a given chromosome in each somatic cell rather than the normal number of two Trisomy 18 is a disorder in which babies are. born with 3 copies of the #18 chromosome ... of Tri...

Somatization disorder

...omatization disorder include: Abdominal pain ... What Is It? A person with somatization disorder is chronically preoccupied with numerous somatic (physical) symptoms over many years. These symptoms, however, cannot ... Somatization disorder is a long-term (chronic) condition in which a p...

Skeletal

... Skeletal muscle is a form of striated muscle tissue existing under control of the somatic nervous system. It is one of three major muscle types, the others being cardiac and smooth muscle. As its name suggests, skeletal ... ... Wi...

Pus

...led pockets formed from periodontitis—an advanced form ... The dairy industry knows that there is a problem with pus in milk. ... The higher the somatic cell count, the more pus in the milk. ... Pus - Definition of Pus at Dictionary.com a free online dictionary with ... Main Entry: pus . P...

Panic Attack

...en, discrete periods of intense anxiety, mounting physiological arousal, fear, stomach problems and discomfort that are associated with a variety of somatic and cognitive symptoms. The onset of these episodes is typically abrupt, and may have... Read about panic attack ( panic disorder) symptoms, ...

Hypochondriac

... those suffering from ... Hypochondriac (hī-pō-kon'drē-ak): a person with somatic over ... Hypochondriac Forum ... Information on Type II Diabetes Meli...he Internet's first ... Hypochondriac (hī-pō-kon'drē-ak): a person with somatic over-concern, including ... Online Medical Dictionary and glossary with...
Somatic in Biological News

Researchers generate functional neurons from somatic cells

Los Angeles, Calif. February 24, 2009 In a new study, researchers were able to generate functionally mature motor neurons from induced pluripotent stem (iPS) cells, which are engineered from adult somatic cells and can differentiate into most other cell types. A potential new source of motor neu...

Bodily breakdown explained: How cell differentiation patterns suppress somatic evolution

Natural selection can occur at the cellular level, where it is detrimental to health. Fortunately it is normally controlled by a well-known pattern of ongoing cell differentiation in the mature tissues of animals, according to a new study published December 14 in PLoS Computational Biology. Th...

Protecting cells from their neighbors

...e body organs and tissues -, and that comprise the somatic cell line. Scientists at the Institute for Researc... CSIC, have identified the mechanism that protects somatic cells against the behaviour of germ cells. When th...ve, but whose signalling also reaches neighbouring somatic cells. The researchers have now discovered that th...

Parasites ready to jump

...iruses carry transposons in their genomes and introduce them into the host cells they infect. Therefore, transposon activity must also be repressed in somatic cells. Recently so-called endo-siRNAs that perform this function were discovered in the fruitfly. A similar class of molecules has been found in mice....

Stem cell research: From molecular physiology to therapeutic applications

...as been studying the mechanism of differentiation and de-differentiation, cellular plasticity and totipotency of pluripotent cells, as well as that of somatic cells. He intends to build various cellular and animal models for human diseases, to uncover mechanisms underlying these different cellular processes ...

Universitat Autonoma de Barcelona researchers first to clone mice in Spain

... removed their chromosomes and substituted them for the nucleus of an adult somatic cell. The cloning of mice is part of a research being carried out to study ...e in levels of gene expression, which would favour the reprogramming of the somatic cell nucleus transferred to the oocyte cytoplasm. Its use in nuclear transf...
Somatic in Biological Technology

An Optimal DNA Microarray Substrate for the Identification of Fetal and Somatic Liver Stem Cells of the Rat

Dr. Frank Stahl GBF Gesellschaft fr Biotechnologische Forschung mbH (Society for Biotechnological Research) Introduction DNA microarrays are a key technology in modern molecular biotec...

SEQUENOM Reports Second Quarter 2009 Financial Results and Highlights

...company continues to benefit from market acceptance of the OncoCarta panel. OncoCarta is a comprehensive multi-gene panel available for profiling rare somatic mutations. It enables researchers to rapidly profile genetic changes associated with tumor initiation and progression. The company expects to add more...

SEQUENOM Announces Launch of MassARRAY Compact 96 System

..., senior vice president of sales & marketing at SEQUENOM. "MassARRAY technology enables detection of the most common molecular biomarker classes - somatic mutations via the OncoCarta mutation panel, SNPs, CNVs, methylation patterns, expression signatures - with an unmatched combination of quantitative ac...

iZumi Bio and Pierian Merge to Form iPierian to Advance Cellular Reprogramming

...ncipal investigator at the Harvard Stem Cell Institute, and assistant investigator at the Stowers Medical Institute. Dr. Eggan is a world authority on somatic cell reprogramming by nuclear transfer, and the applications of iPS cells to model neurodegenerative disease. Dr. Matthias Hebrok, Hurlbut-Joh...

iZumi Bio Appoints Dr. Corey Goodman to Board of Directors and Scientific Advisory Board

...., in the area of cardiovascular disease to identify potential targets that address unmet medical need. iZumi's technology involves reprogramming somatic cells to a pluripotent state. Because iPS cells have stem-cell-like properties and have the potential to differentiate into any cell type, iPS cells a...

Transgenomic Completes Licensing Option With Dana-Farber Cancer Institute on Cold-PCR for Enrichment of DNA Mutations

...es in samples where DNA sequencing cannot detect very low concentrations of somatic DNA mutation. "We are very excited to be able to work with Dana-Farbe...r Nuclease promises a significant solution to high sensitivity detection of somatic mutations that are key to cancer biology." Cold-PCR will have applicab...
Somatic in Biological Products

Mouse Anti-Salmonella typhimurium Monoclonal Antibody, Unconjugated, Clone 6331 from GeneTex

Description:...e bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major antigens; the "H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS ...
Company:GeneTex
Somatic in Biological Definition

Allele

... red petals, while another might result in white petals. Some organisms are diploid - that is, they have paired homologous chromosomes in their somatic cells , and thus contain two copies of each gene. An organism in which both copies of the gene are identical - that is, have the same allele - is said...

Allele frequency

...t locus, c) a population of individuals carrying n loci in each of their somatic cells (e.g. two loci in the cells of diploid species, which contain two ... allele (i.e. carry one copy of that allele and one copy of another in each somatic cell) and 4% will be homozygous (carrying two copies of the allele). So ...

Antibody

...tigens they are specific for and that elicited their production. The ability to bind a wide variety of foreign antigens arises from events know as somatic recombination. This is when genes are selected (variable (V), diversity (D) and joining (J) for heavy chains, and only V and J for light chains) to f...

Cell growth

...ch as the human organism, most cells of the body have the haploid amount of DNA, 2N . Using this notation for counting chromosomes we say that human somatic cells have 46 chromosomes (2N = 46) while human sperm and eggs have 23 chromosomes (N = 23). Humans have 23 distinct types of chromosomes, the ...

Chromosome

...omes (Table 1). Asexually reproducing species have one set of chromosomes, which is the same in all body cells. Sexually reproducing species have somatic cells (body cells), which are diploid [2n] (they have two sets of chromosomes, one from the mother, one from the father) or polyploid [Xn] (more ...

Cloning

...ion. Cloning an organism means to create a new organism with the same genetic information as an existing one. In a modern context, this can involve somatic cell nuclear transfer in which the nucleus is removed from an egg cell and replaced with a nucleus extracted from a cell of the organism to be cl...
Somatic in Biological Dictionary

Somatic

The term somatic refers to cells of the body, rather than gametes (eggs or sperm). In humans, somatic cells contain two copies of each chromosome (diploid), whereas gametes only contain one copy of each chromosome (haploid). Although all somatic cells of an individual are geneticall...

Voluntary muscle

... Skeletal muscle is a form of striated muscle tissue existing under control of the somatic nervous system. It is one of three major muscle types, the others being cardiac and smooth muscle . As its name suggests, skeletal... These mu...

Transposable element

... in the Columbia Encyclopedia, Computer Desktop Encyclopedia, computing ... Some maize phenotypes caused by transposable elements excising in somatic tissues. ... P-elements are transposable elements that carry genes for transposase activity ... shown to consist of transposable element ...

Telomerase

...and that preserves the Telomerase is an enzymatic ribonucleoprotein complex that acts as a reverse ... Telomerase activity is almost absent in somatic cells, but it is detected in ... UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase , the enzyme...

Spermiogenesis

...e ... ... are likely to result from abnormalities in spermiogenesis (Huang et al, ... During the second half of spermiogenesis , replacement of somatic histones by ... ... those genes that optimize spermatogenesis and spermiogenesis have been selected ... reported that defective spermiogene...

Spermatogenesis

...GENESIS . Spermatogenesis is the process of sperm cell development. ... the X chromosome that inhibit spermatogenesis are inactivated in XY somatic cells. ... Shop for Proteomics of Spermatogenesis - Books at Shop.com. Books|Non-Fiction|English |Hardcover|Science|Springer Verlag|G. S. Gupta ...
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