Penn researchers gain new insights on spinal muscular atrophy
...e inventory of the different types of snRNPs in all cells, what we call the snrnp
repertoire or the 'snRNPertoire,'" says Dreyfuss. "When SMN levels are reduced, the biochemical balance needed to make the snrnp
complexes for splicing RNA is impaired."
The Dreyfuss lab looked at redu...
SnRNP in Biological News
A new gene silencing platform -- silence is golden
...ration step of polyA tail addition in a gene specific manner. Further, the domains of the oligonucleotide are independent so transcript binding and U1 snrnp
binding can be independently optimized and adapted to a wide array of genes associated with disease.
"The U1 Adaptor platform expands on early tech...
SnRNP in Biological Technology
Fermentation Cell Culture: University Style
...tural hosts. Several factors
prevent the conventional overexpression
bacteria. First, many individual
snRNP proteins are insoluble in the
absence of their binding partners.
Second, many snrnp
100 to 280 kD in mass, making
their overexpression in E. c...
SnRNP in Biological Dictionary
RNA splicing: intron/exon · snRNP
· spliceosome (minor spliceosome, U1) · alternative splicing ... Retrieved from "http://en.wikipedia.org /wiki/ SnRNP
" ... Evidence that U5 snRNP
recognizes the 3' splice site for ... RNA splicing: intron/exon · snRNP