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Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

Potential late-stage ovarian cancer therapy; currently none available; Diphtheria-encoding genes delivered to tumor site by nanoparticles; Laboratory research; possible human trials about 18 months away Philadelphia (Vocus) July 29, 2009 -- Nanoparticle delivery of diph...

Growth in Drug Sales of the Top 10 Pharmaceutical Companies Slowed to its Lowest Level in Years in 2008

Pharma's Premier Quantitative Company and Drug Evaluation Tool Designed Specifically for Business Development Available Now with a New User-Friendly Interface Productview Plus from Decision Resources Includes Data for Over 1000 Drugs Across 147 Product Classes WALTHAM, Mass., May 12 /PRN...

Some Countries May Have Slowed Bird Flu's Spread

Strains from China didn't make it to Vietnam, Thailand, study finds WEDNESDAY, Feb. 27 (HealthDay News) -- Several strains of H5N1 bird flu virus that afflicted southern China were blocked from entering neighboring Thailand and Vietnam, say University of California, Irvine, researchers...

Alzheimer's Can Be Slowed Down By Gold Nanoparticles

A combination of radiation and gold nanoparticles can help in slowing down the progress of Alzheimer's disease, according to a research conducted by scientists from Spain and Chile. The healthy brain // cells will not be affected by this. According to their study, to be published in the American...

West Announces Second Quarter 2009 Results

...roved contract manufacturing revenue for healthcare products, including injection pens and components, auto-injectors and medical filters, while sales slowed for consumer product-related molding and assembly. Gross profit was $11.8 million in the quarter, a 13.5% increase over the second quarter of ...

'Suicide' Genes Help Slow Ovarian Tumor Growth in Mice

... THURSDAY, July 30 (HealthDay News) -- Treatment with "suicide" genes slowed ovarian tumor growth in mice and may one day offer a way to treat late-stag...in-encoding DNA selectively expressed in ovarian cancer cells significantly slowed the growth of ovarian tumors. The findings appear online in the journal Ca...

Elected Officials Voting Against Health Reform Received 65% More in Campaign Donations From Health and Insurance Interests Than Those Voting for Reform

... in campaign contributions from the health and insurance industries than those who voted for reform. In addition, the legislation appears to have been slowed in two final committees whose members received much more from the health and insurance industries than their colleagues on the three committees that h...

GSK - Improving Performance to Continue in Second Half

...ccine, european and emerging markets businesses and whilst the US remains under pressure from older products going off patent, the rate of decline has slowed down. Talking about the improving outlook for the second half of the year, Andrew Witty, GSK Chief Executive, said: "As we go into the second h...

Lighter Meals May Bring Longer Life

...vidence yet that fewer daily calories boost lifespan THURSDAY, July 9 (HealthDay News) -- A new study that found that a lower-calorie diet slowed the aging process in monkeys could be the best proof yet that restricted diets might do the same for humans. "The big question in aging research is...

Antidepressants aid electroconvulsive therapy in treating severe depression

...ical stimulus to the brain to induce seizures. It is prescribed for patients with crisis-level severe depression who are catatonic (people who are so slowed down that they stop moving, talking and eating) or suicidal or for patients with major depression who have not responded to medication. Electrodes at...
slowed in Medical Technology

Data Presented at the American Heart Association Scientific Sessions 2007 Demonstrated Increased HDL with ACTOS(R) (pioglitazone HCl) Slowed the Progression of Carotid Intima-Media Thickness in Patients with Type 2 Diabetes

ORLANDO, Fla., Nov. 6 /PRNewswire/ -- What and When Additional results from the clinical trial, CHICAGO (Carotid intima-media tHICkness in Atherosclerosis using pioGlitazOne), will be presented as an oral session at the American Heart Association Scientific Sessions 2007 being held November ...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

...isorder in older adults after Alzheimer's. Every nine minutes someone is diagnosed with Parkinson's disease. Symptoms include tremor, muscle rigidity, slowed motion, shuffling gait, and a loss of facial expression. The symptoms vary from individual to individual, but become more severe over time. Although p...

CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis

...R (ROSUVASTATIN CALCIUM): Studies have previously shown that CRESTOR significantly lowered LDL-C, had a significant effect on raising HDL-C and slowed the progression of atherosclerosis, the build-up of plaque in the arteries. CRESTOR has now received regulatory approval in over 90 countries. ...

CRESTOR(R) Reduced Risk of Blood Clots in the Veins

...R (ROSUVASTATIN CALCIUM): Studies have previously shown that CRESTOR significantly lowered LDL-C, had a significant effect on raising HDL-C and slowed the progression of atherosclerosis, the build-up of plaque in the arteries. CRESTOR has now received regulatory approval in over 90 countries. ...

Mayo Clinic Study Finds Younger Men With Erectile Dysfunction at Double Risk of Heart Disease

...ame issue of Mayo Clinic Proceedings. The results "raise the possibility of a 'window of curability,' in which progression of cardiac disease might be slowed or halted by medical intervention," writes Dr. Miner, who practices at the Men's Health Center, Miriam Hospital, Providence, R.I. Erectile dysfu...

Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TV's 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol

...ot calorie restriction Additionally, researchers recently reported resveratrol does not produce the same characteristic drop in body temperature and slowed heart rate seen in calorie restriction. So, plain resveratrol may not be a true mimic of the effects of calorie restriction. Furthermore, researc...

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

...patients who withdrew from RAPID 1 and 2 trials because they did not achieve an ACR20 response at Week 12 (confirmed at Week 14) nevertheless showed a slowed progression of structural damage within the joints as measured at Week 16 by analysis of radiographic data. Additional data presented focused on the...

Joint Commission Urges Patients to 'Speak Up' About Pain

...life, right? Maybe not. Pain is actually one of the main reasons that Americans seek medical treatment, and untreated pain can have serious effects -- slowed recovery times, poor quality of life and higher health care costs. The Joint Commission is launching a national campaign to help Americans work with...

Olanzapine Long-Acting Injection (LAI) Shown to Maintain Treatment Benefit in Schizophrenia for up to Six Months

...L cholesterol or triglycerides increased over time. In adult patients who completed 9-12 months of therapy, the rate of increase in mean blood glucose slowed after approximately 4-6 months. As with all antipsychotic medications, a rare and potentially fatal condition known as Neuroleptic Malignant Syndrom...

Groundbreaking American Journal of Play from Strong National Museum of Play(R) Premiers July 2008

...e most prominent national researchers and writers in the field--from a neuroscientist's assertion that the rising tide of ADHD among children might be slowed by starting each school day off with recess, to a psychologist's surprising findings on the role of imaginary child companions, to a historian's panor...
slowed in Medical Dictionary

Sunburn

...ffects the health of your skin. ... You get a sunburn , that is, unless you happen to have taken the time to get a gradual tan. ... Featuring the slowed down sounds of San Frandisco. Artists include Hawke, Charlotte the Baroness, and the Infinite Posse. User-edited article about the burning of ski...

Silicosis

... disease, is caused by ... Silicosis is the oldest known environmental lung disease. ... Silicosis cannot be cured, but its progression can be slowed if exposure to ... Offers details of those at risk, treatment, prevention, resources, and more. ...

Prognathism

...gnment of the biting surfaces of the ... Medical history questions documenting prognathism in detail may include: ... Prognathism . Breathing - slowed or stopped. Coloboma of the iris. Claw foot ... Prognathism - Overview, Prognathism is an extension of the lower jaw (mandible) ... Definiti...

Macular Degeneration

...rcise May Protect Eyesight ... WebMD looks at macular degeneration , the leading cause of severe vision loss in people over age 60. It can be slowed down with appropriate treatment. Age-Related Macular Degeneration (AMD) Test -- Amsler Grid(Prevent Blindness America) ... Living with AMD( Ma...

Hiv infection

...infection has sex ... The mean interval between infection with HIV and the onset of AIDS exceeds ... Transmission of HIV infection can be slowed or halted by reducing or eliminating ... Human immunodeficiency virus infection . Causes ... related to HIV infection include: Diarrhea. Fa...

Heart block

...ttack), heart ... Heart block occurs when the electrical signal is slowed or disrupted as it moves ... If you're born with it, it's called congenita...ng to find the ... Heart block occurs when the electrical signal is slowed or ... Heart block is a type of arrhythmia. ... You can be born with h...

Emphysema

... chronic obstructive pulmonary disease n. ( Abbr. COPD ) A chronic lung disease, such as asthma or emphysema , in which breathing becomes slowed or Emphysema — Comprehensive overview covers symptoms, causes, treatment and prevention of this ... As it worsens, emphysema turns the sph...

Drug Addiction

...iction involves the progression of acute drug use to the development of drug -seeking behavior, the vulnerability to relapse, and the decreased, slowed ability to... Drug addiction — Comprehensive overview covers signs, symptoms, causes, treatment of this chemical dependence. ... Breaking a ...

Dependence

...ddiction involves the progression of acute drug use to the development of drug-seeking behavior, the vulnerability to relapse, and the decreased, slowed ability to... The term "addiction" is used in many contexts to describe an obsession, compulsion, or excessive psychological dependence...

Chronic obstructive lung disease

...ronic obstructive pulmonary disease n. ( Abbr. COPD ) A chronic lung disease , such as asthma or emphysema, in which breathing becomes slowed or The Canadian Lung Association - asthma, COPD, tuberculosis, sleep apnea, emphysema, quit smoking, ... COPD stands for Chronic Obstructive ...
slowed in Biological News

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

PHILADELPHIA Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research , a journ...

Holding breath for several minutes elevates marker for brain damage

...raining to increase their lung capacity while learning crucial safety measures. Breath-hold diving often leads to hypoxia, elevated blood pressure, slowed heartbeat and other physiological changes. However, whether the sport causes any long-term damage to the brain has remained a point of contention. Stu...

2000-year-old statue of an athlete sheds light on corrosion and other modern challenges

...o evaluate how underwater fouling organisms and communities interacted with the statue as well as how certain mineral deposits on the bronze sculpture slowed its deterioration. ...

New nanoparticles could revolutionize therapeutic drug discovery

...es in drug discovery. Understanding the structure of proteins is a vital first step in developing new drugs, but to date, drug development has been slowed because due to their instability, proteins are difficult to work with in lab conditions. However, using nanoparticles, scientists from the Universitie...

Global sunscreen won't save corals

...ch a scheme on ocean acidification had never been calculated. In the simulations, reduced sunlight cooled the planet as expected,,and it also slightly slowed the rise in atmospheric carbon dioxide, as more carbon was absorbed by natural sinks. But this slight change was not enough to significantly mitigate ...

Bird songs change with environment

...hanged in each place. Using computer software to compare the songs then and now, she found that where vegetation had gotten thicker, the birdsongs had slowed down significantly in tempo. "It's pretty good evidence that vegetation density can influence birdsong over time," Derryberry said. Why would th...

UC Davis bioengineer receives Hartwell Foundation grant to address skull fusion disorder of infants

...tion a portion of them along the sutures to protect the exposed brain. The hope is that by removing some bone and rearranging the rest, growth will be slowed long enough to allow the brain to reach full size. But in 6 to 8 percent of cases, a second operation is necessary, and in 25 percent of those case...

American Chemical Society's weekly PressPac -- April 29, 2009

... the trail of wastes released by the first droplet. Then the two move together in a "communicative" manner. When the fuel was exhausted, the droplets slowed down and stopped. The study serves as a long-awaited blueprint for designing similar locomotion systems in artificial cells, the scientists say. MTS...

Penn biologists discover how 'silent' mutations influence protein production

... folding and thereby the eventual protein level. The researchers also identified a class of mutations that did not directly affect protein levels but slowed bacterial growth. For biologists, these results fundamentally change the understanding of the role of synonymous mutations, which were previously ...

A sticky business -- how cancer cells become more 'gloopy' as they die

...l death." However, the researchers noted that as viscosity in the cancerous cell increases, the toxic oxygen molecule's mission to kill the cell is slowed down too. Dr Kuimova explains: "It looks like whilst the increasing viscosity contributes to the cell's demise, these new 'sticky' cell conditions ...
slowed in Biological Technology

Ceregene Receives Additional Grant From Michael J. Fox Foundation to Expand Long-Term Testing of CERE-120 Patients

... Parkinson's disease is a progressive movement disorder that affects a million people in the United States. Its main symptoms, stiffness, tremors and slowed movements and gait, are caused by a loss of dopamine-containing nerve cells in the substantia nigra, which project their axons to the putamen. Dopamin...

New angle on gecko research

...tudied applied their adhesive system on a 10 degree slope. At 30 degrees all six applied the system. The three that applied the traction at 10 degrees slowed down, the three that didn't were much quicker. "There are costs, in terms of speed, and benefits, in terms of traction, associated with this switch...

The MedZilla Report: June 2009 Employment Outlook for Biotech/Pharma/Health

...new employees. They topped eight percent. Three states increased by more than three percent, and three more by more than two. Illinois-based companies slowed their search efforts by more than five percent in June, with four other states also showing slowdowns of two percent or more. As for jobs being posted...

Neogen Reports 16% Increase in Revenues

... year. Sales of Neogen products that require a capital investment, including AccuPoint((R)) readers and Soleris((TM)) microbial detection instruments, slowed in 2009 due to the impact of the economic downturn. However, sales of associated disposable AccuPoint samplers and Soleris vials increased sharply--pr...

Essilor : First Half 2009 Revenue

...nt. The only exception was in Japan, where Nikon-Essilor nevertheless increased its share of a still depressed market. In Latin America, growth slowed for the period, partly due to the comparison with the 17.6% gain reported in first-half 2008. However, business in Brazil and Latin America benefited ...

STALLERGENES: Strong Sales Growth in 1st Half-Year: up 12% Full-Year Guidance Maintained

...) Portugal, Spain, France, Italy, Greece; (2) Switzerland included HY1 sales 2nd quarter growth remained high at 9% (organic* 8%), but slowed down compared with the very strong start of the year. Sales growth over the first half-year remained strong at 12% (organic 11%), reflecting the conti...

New method may accelerate drug discovery for difficult diseases like Parkinson's

... disease that was created in the Lindquist lab. Parkinson's disease is a neurodegenerative disorder characterized by tremors, muscle rigidity, and slowed movements. In the neural cells of Parkinson's patients' brains, researchers have noted Lewy bodies, abnormal aggregates primarily composed of the prot...

Novel drug discovery tool could identify promising new therapies for Parkinson's disease

...control and coordination. As those neurons degenerate, the disease leads to progressive deterioration of motor function including involuntary shaking, slowed movement, stiffened muscles, and impaired balance. The neurons normally produce a chemical called dopamine. A synthetic precursor of dopamine called L...

Rodobo International, Inc. Reports Q2 and First Half of 2009

...tated: "During the first six months of our fiscal year, Rodobo International has experienced an impressive growth in revenues and earnings. This trend slowed down during the second quarter. We keep developing distribution networks and we're currently covering 4,463 retail stores in 6 provinces: Sichuan, Sha...

Transgenomic, Inc. Reports First Quarter 2009 Results

...e have added an additional 24 new ordering institutions during the first quarter of 2009. This business was also impacted by the current economy which slowed our quarterly growth rates. We believe this is the result of potential patients delaying diagnostic testing during the current economic tumult since w...
slowed in Biological Dictionary

G1 phase

...classifications of G1 phase ... The length of the G1 phase creates the difference between fast dividing cells ... The G1 phase can be slowed by reducing the nutrients available in a system ... The restriction point in the G1 phase of the mammalian cell cycle is the oldest, ... Ce...

G2 phase

...e G2 - phase ... G2 - phase and then assaying for ... suggest that plants may regulate the G2 - phase checkpoint in ... The G1 phase can be slowed by reducing the nutrients available in a system ... is made up of two identical chromatids), the cell moves onto the G2 phase . G2 Phase ... ...

Agarose Gel

...Running an Agarose Gel ) ... Agarose Gel Electrophoresis. Introduction: Agarose gel electrophoresis is ... toward the positive pole is slowed by making the DNA move through an agarose gel . ... Agarose gel electrophoresis is your portal for all the agarose gel methods and ......
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