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Simulations in Medical News

Running shipwreck simulations backwards helps identify dangerous waves

ANN ARBOR, Mich.---Big waves in fierce storms have long been the focus of ship designers in simulations testing new vessels. But a new computer program and method of analysis by University of Michigan researchers makes it easy to see that a series of smaller waves---a situation much more likel...

Pitt receives $13.4 million NIH grant to create virtual models for epidemics

...ram, funds the development and testing of computer simulations that will ultimately enable public health official...c Health, uses census and other data sets to build simulations of individuals as they move about and interact wit...officials. These projects build on large-scale simulations previously developed by Dr. Burke and his colleagu...

Higher drug doses needed to defeat tuberculosis, UT Southwestern researchers report

...variability of this particular drug is patient weight and gender, so in our simulations we took that into account," Dr. Gumbo said. "What we found is that we're re...on will fare in actual patients. With this model, researchers can use these simulations to determine the duration of therapy, which could shorten from years to mon...

Breast cancer research highlights from the American Association of Physicists in Medicine meeting in Anaheim, July 26-30

...eliver a lethal dose of X-rays to cancer cells inside a tumor while sparing healthy tissue. So far, they have measured dose distribution and performed simulations to show the feasibility of such a system, which Boone will describe in Anaheim. The talk, "Breast CT as a Platform for Image Guided Therapies of Br...

Simulating medical situations helps students learn, retain basic science concepts

... stopped action periodically to lead the group in discussion of the basic neuroscience concepts being learned during the scenario. Typically, such simulations are used in small groups and in clinical settings, but the School of Medicine started experimenting with the use of simulation in student neuroscience...

B-Line Medical(R) and Mentice, Inc. Announce Data Integration Partnership

...ve helped over eighty top hospitals, medical schools and nursing programs in the U.S., Canada and Europe, operate and manage their clinical skills and simulations centers more effectively. From the affordable and portable SimCapture to the powerful and highly automated SimBridge(R), B-Line Medical solutions max...

B-Line Medical(R) and Surgical Science Sign Data Integration Agreement for LapSim(R) Simulator

...e helped over eighty top hospitals, medical schools, and nursing programs in the U.S., Canada, and Europe operate and manage their clinical skills and simulations centers more effectively. From the affordable and portable SimCapture to the powerful and highly automated SimBridge(R), B-Line Medical solutions maxi...

Obese Get Higher Doses of Radiation for X-Rays

... researchers note. To gauge how high radiation doses must be to get effective X-rays for overweight and obese people, the researchers used computer simulations that delivered X-ray beams at various strength levels to so-called "phantom" patients representing five different fat tissue levels, from lean to obes...

Western Governors University Nursing Education Program Receives $500,000 Grant from the Texas Workforce Commission

...ity nursing education more accessible to working adults. The program combines WGU's online, competency-based academic approach with intensive clinical simulations and clinical practice at partner hospitals, supervised by onsite clinical coaches serving as WGU adjunct faculty. Texas is the second state to launch ...

Gene Network Sciences Announces Cancer Collaboration with University of Connecticut Health Center's Neag Comprehensive Cancer Center

... The parties will utilize the Neag Comprehensive Cancer Center's clinical expertise to assess and validate findings from the ovarian cancer model simulations and will work with strategic partners to make drugs and diagnostics created based on these discoveries available to patients. They are also currently ...
Simulations in Medical Technology

Cytel Signs Cooperative Research And Development Agreement With FDA Center for Devices and Radiological Health (CDRH)

...ting characteristics of each Bayesian submission separately. This is an inhibiting factor and puts considerable burden on sponsors in carrying out the simulations that are submitted to CDRH and on CDRH statisticians in validating what is submitted. About Cytel Cytel Inc. is a leading provider of s...

Phase III Data Demonstrate Efficacy and Tolerability of Carisbamate as an Adjunctive Therapy for Partial Onset Seizures

...parately, a statistically significant positive relationship between seizure rate reduction and steady state trough concentrations was found. The PK/PD simulations predicted that treatment with 400 mg/day provides clinically meaningful effects for all subjects, with further increase in effect with dosages of 800 ...

Vascular Surgeons Agree: Case Rehearsal Improves Outcomes

... strongly disagree) were completed assessing face validity, or the degree to which the simulation mimicked real life. Results: Five patient-specific simulations were performed. The surgeons "strongly agreed" (median score 5/5) that the simulation improved the operative flow, increased patient safety and effici...

Universite de Montreal Researchers Simulate World's Largest Heart Model Using SGI Technology

...dden cardiac death that are linked with Brugada syndrome. However, computer simulations have shown that this is not the case. Additional factors are needed. Such a... mechanics of HIV protease, genomic correlation for cancer research, and 3D simulations of surgeries," said Michael Brown, Director of Sciences Markets, SGI. "The ...

Pharsight Uses FDA Disease Model to Support Oncology Drug Development

...ght scientists are using FDA's publicly available model in NSCLC to perform simulations of expected survival based on tumor shrinkage for an investigational drug in early clinical studies. Pharsight scientists also expect to refine these simulations with emerging data in new clinical studies to assist with key oncology deve...

NKTR-102 (PEG-Irinotecan) Demonstrates Significant Tumor Growth Inhibition In Multiple Preclinical Tumor Models

...was associated with its anti-tumor activity in lung and colorectal models using pharmacokinetic (PK) and pharmacodynamic (PD) modeling. Further, PK/PD simulations performed with irinotecan administration show that a continuous infusion of irinotecan at 240 mg/kg would be required to achieve the equivalent tumor ...

Favrille Provides Update on Timing of Analysis from Pivotal Phase 3 Clinical Trial; Reports Third Quarter 2007 Financial Results

... calculations are appropriate; the most significant of which is the behavior of the control group. The guidance from the independent DMB combined with simulations we have performed based on the long-term follow-up from our Phase 2 trial gives us confidence that the timing of this analysis will provide adequate p...
Simulations in Medical Definition

Telephone Triage

...ill be a minimum of 40 hours and will include online training based on “real life” problems. Sophisticated training programs will provide patient call simulations from off site and nurses utilizing telemonitoring and electronic protocols. Because telephone triage is an international phenomenon, conferences of ...
Simulations in Medical Dictionary

Cochlear implant

...eers at Cochlear . ASX Announcements. Vistafix product information ... Cochlear implants in children. Factors affecting performance. Acoustic simulations of cochlear implants . Conclusions. References ... This page is an overview of insurance payment for cochlear implant services ... Which c...
Simulations in Biological News

Computer simulations explain the limitations of working memory

[PRESS RELEASE, 31 March 2009] Researchers at the Swedish medical university Karolinska Institutet (KI) have constructed a mathematical activity model of the brain's frontal and parietal parts, to increase the understanding of the capacity of the working memory and of how the billions of neurons ...

New open-source software permits faster desktop computer simulations of molecular motion

Whether vibrating in place or taking part in protein folding to ensure cells function properly, molecules are never still. Simulating molecular motions provides researchers with information critical to designing vaccines and helps them decipher the bases of certain diseases, such as Alzheimer's an...

Are existing large-scale simulations of water dynamics wrong?

MADISON, WI -- Soils are complicated porous media that are highly relevant for the sustainable use of water resources. Not only the essential basis for agriculture, soils also act as a filter for clean drinking water, and, depending on soil properties, they dampen or intensify surface runoff and t...

Computer simulations point to key molecular basis of cystic fibrosis

Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis, which about 1 in 3000 children are born with in the US every year. The findings, published February 29 in the open-access journal PLo...

Large-scale Computer Simulations Reveal New Insights Into Antibiotic Resistance

Novel use of genetic testing methods helped public health officials control and limit the further spread of four outbreaks of foodborne hepatitis A virus in 2003 related to the consumption of green onions, according to a detailed analysis published in the October 15 issue of The Journal of Infectio...

Scientists find universal rules for food-web stability

...erving natural environments, or by computer simulations. To enable computer simulations of such systems, scientists often have to make simplifying assumptions, kee...model parameters as low as possible. Yet, the computational demands of such simulations are high and their relevance is often limited. Innovative methodology ...

AGU journal highlights -- Aug. 6, 2009

... and find that including ozone depletion produced a significant reduction in Southern Ocean carbon uptake, in good agreement with observed trends. The simulations show that ozone depletion, combined with increased atmospheric greenhouse gas concentration, drives stronger winds above the Southern Ocean. These str...

Symposium to discuss geoengineering to fight climate change at the ESA Annual Meeting

...t despite its potential to create overall cooling, atmospheric seeding could cause significant changes in localized temperature and precipitation. Her simulations also predict that sulfur seeding could destroy atmospheric ozone, leading to increased ultraviolet radiation reaching the Earth's surface. "An inc...

August 2009 Geology and GSA Today media highlights

...d ice sheet-atmospheric general circulation model in an attempt to simulate both observed glacioeustatic changes and inferred ice sheet volumes. Their simulations present paradoxical results. While ice volumes of similar size to those implied by proxy evidence are simulated, sea-level changes brought about by cy...

New computer simulation helps explain folding in important cellular protein

...se of algorithms with repeated random samplings to produce reliable predictionshave been around for some decades but have been steadily refined. These simulations are useful for extremely complex problems with multiple variables, and though they often require considerable computer "brain power," they are able to...
Simulations in Biological Technology

Medical simulations identify potential problems before they can pose a real threat

Madison, Wis. As the medical business struggles with the problems of clinical risks and litigation, one emerging method for dealing with potential problems is through the use of war-game exercises, in which scenarios that could last for several chaotic days in the real world can be simulated in ...

Muscular protein bond -- strongest yet found in nature

... of proteins that is, it "reads" the same way forward and backward in which two titin molecules are connected by another muscle protein, telethonin. simulations have pointed toward a network of tight hydrogen bonds linking titin and telethonin as a source of stability. But direct measurements that would furthe...

Nanopillars promise cheap, efficient, flexible solar cells

...ectrodes to produce a current. Unlike a typical two-dimensional solar cell, a nanopillar array offers much more surface for collecting light. Computer simulations have indicated that, compared to flat surfaces, nanopillar semiconductor arrays should be more sensitive to light, have a greatly enhanced ability to ...

ClearTrial to Chair Session at DIA 45th Annual Meeting on "Effective Operational Planning for Adaptive Clinical Trials"

...erstanding the potential for changes in resource allocations and demands in areas such as biostatistics and drug supply, to the need for more accurate simulations of differing trial scenarios and their operational elements. During this session, the panel of experts will examine these challenges and provide p...

Frost & Sullivan Awards Precision Biosciences for Technology Innovation and Molecular Design Process in the Genomics Market

...; Sullivan's Dr. Sudeep Basu. "The DNE technology is an amalgamation of core enzyme catalysis, high-specificity DNA targeting, computational molecular simulations for structural modeling, and rational mutagenesis to design a set of extremely specific 'molecular scissors' for the precise engineering of large geno...

Bridging the gap in nanoantennas

...eans of full electrodynamic calculations. The calculated maps of the antenna fields are in good agreement with the experimentally observed images. The simulations add deep insights into the dependence of the antenna modes on the bridging, thus confirming the validity and robustness of the "loading" concept to ma...

New security and medical sensor devices made possible by metallic nanostructures

...ogy, said: "Pairing up these structures has a unique effect on the way they scatter light an effect which could be very useful if, as our computer simulations suggest, it is extremely sensitive to changes in surrounding environment. With further testing we hope to show that it is possible to harness this pro...

Researchers find better way to manufacture fast computer chips

...con oxide and pull it away, you can 'split the deck' near the point of contact, leaving some layers of graphene behind. What we found through computer simulations was that the graphene surface interacts so strongly with the silicon oxide surface that the chemical bonds between the graphene layers weaken, and the...

Latest issue of Science: Nanosonar uses electrons to measure under the surface

...d methods will make it possible to gain a detailed understanding of deep impurities and interfaces between atomic lattices," explained Lounis. For his simulations of the scanning tunnelling experiment, he used the supercomputer known as JUMP in the Jlich Supercomputing Centre. In a related article in the "Pe...

Latest issue of Science: Nano-sonar uses electrons to measure under the surface

...d methods will make it possible to gain a detailed understanding of deep impurities and interfaces between atomic lattices," explained Lounis. For his simulations of the scanning tunnelling experiment, he used the supercomputer known as JUMP in the Jlich Supercomputing Centre. In a related article in the "Pe...
Simulations in Biological Definition

Artificial life

...s this phenomenon, but it could be something as simple as..." The field is characterized by the extensive use of computer programs and computer simulations which include evolutionary algorithms (EA), genetic algorithms (GA), genetic programming (GP), artificial chemistries (AC), agent-based mode...

Bioinformatics

...g. See also structural motif . Modeling biological systems Main article: Systems biology Systems biology involves the use of computer simulations of cellular subsystems (such as the networks of metabolites and enzymes which comprise metabolism , signal transduction pathways and gene reg...

Bioinformatics

...g. See also structural motif . Modeling biological systems Main article: Systems biology Systems biology involves the use of computer simulations of cellular subsystems (such as the networks of metabolites and enzymes which comprise metabolism , signal transduction pathways and gene reg...

Origin of life

...ion is the origin of homochirality , i.e. all monomers having the same "handedness". This is essential for both proteins and DNA, yet many prebiotic simulations produce a racemic , or 50/50 mixture of left- and right-handed forms. From organic molecules to protocells As the question how organic molecul...

Astrobiology

...iverse is a verifiable hypothesis (though it has yet to be verified), making xenobiology a valid field for scientific enquiry. Likewise, computer simulations of basic life processes have made it possible to do exploratory engineering of alternate life forms (like left-handed DNA ) to determine their char...
Simulations in Biological Dictionary

Tobacco mosaic virus

...mportant virus disease of tomato ... Satellite Tobacco Mosaic Virus (STMV) Satellite Tobacco Mosaic Virus is a ... Molecular dynamics simulations of the complete satellite tobacco mosaic virus . ... Tobacco mosaic virus ... Information on Tobacco Mosaic Virus of Tomato includ...

Tissue

...... dense irregular connective tissue , human, H&E - non-lactating breast. reticular connective tissue , reticulin - liver. Focus & Stage simulations ... IMGENEX offers a large selection of antibody reagents to factors that are involved in the cascade of number of key factors including oncoge...

Phospholipid bilayer

...made from monolayers on patch-clamp pi... a reasonable model of a phospholipid bilayer , we have studied the system using ... Molecular Dynamics simulations and H NMR Study of the GalCer/DPPG Lipid Bilayer ... Galactocerebroside- phospholipi d interactions in bilayer membranes ... measure phosph...

Phospholipid

...Choline helps form phosphatidylcholine, the primary phospholipid of cell membranes. ... Phospholipid bilayers have been studied with computer simulations that follow ... was composed of a single type of phospholipid and no cholesterol was present. ... phospholipids , ... Individual phospholipid ...

Ion channel

...ices are called ion channels . ... It is common that a type of ion channel will allow several kinds of ions to ... ion channel links ... simulations of Ion Channels and Excitable Membranes ... Ion Channel Laboratories from IonChannels.org ... Ion channels are a special class of pr...

In silico

...es informatics is the ... In Silico . Products. ActivityBase Suite. Biology. Chemistry. XE - Screening. SARview. E-WorkBook Suite ... Computer simulations and visualizations are performing the thought experiments of the 21st century and pushing the limits of human vision and imagination. View video....

Artificial life

... Artificial life is a field of study and an associated art form which examine systems related to life , its processes, and its evolution through simulations using computer models, robotics, and biochemistry. There are three... Synthetic life and artificial life are terms used for attempts to recreat...
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