Used in a new way, RNA interference permanently silences key breast cancer gene
In laboratory mouse experiments, researchers at The University of Texas M. D. Anderson Cancer Center have developed a way to use RNA interference (RNAi) so that it permanently hampers breast cancer development. The technique permanently silences activated STAT3, a crucial gene found in some human breast tumors, thus reducing the cancer's ability to become invasive. The study, presented at...Interfering RNA silences genes in 'slippery' immune cells
A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. RNA interference has recently emerged as an important tool in studying how genes function in normal biological processes and in disease. Writing in the Journal of Immunological Methods, published online on March 24, a researc...Researchers find protein that silences genes
A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off –in this case, the turning off of thousands of nearly identical genes in a hybrid plant. Studying the phenomenon of nucleolar dominance, in which one parental set of ribosomal genes in a hybrid is silenced, Craig Pikaard, Ph.D., Washington Un...MIT: Pulsing light silences overactive neurons
Scientists at the MIT Media Lab have invented a way to reversibly silence brain cells using pulses of yellow light, offering the prospect of controlling the haywire neuron activity that occurs in diseases such as epilepsy and Parkinson's disease. Such diseases often must be treated by removing neurons that fire incorrectly. The new MIT research could lead to the development of optical brai...Commonplace Sugar Compound Silences Seizures
Though in clinical use for decades, a small, sweet-tasting compound is revealing a startling new face as a potential cure for epilepsy.// 2-deoxy-glucose, or 2DG, has long been used in radio labeling, medical scanning and cancer imaging studies in humans. But now, researchers at the University of Wisconsin-Madison have found the substance also blocks the onset of epileptic seizures in...Holmes Silences Pregnancy Rumours
Hollywood actress and wife of superstar Tom Cruise, Katie Holmes has silenced rumours that she is pregnant by showing off her figure in a revealing swimsuit. Hollywood.com reports that there were rumours that Holmes was in the early stages of pregnancy after she looked like she had a round stomach in Madrid. The couple wed last November and already have a 14-month old...