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Mitochondrial DNA mutations play significant role in prostate cancer

Mutations in mitochondrial DNA (mtDNA) playan important role in the development of prostate cancer, according toresearch by scientists at Emory University School of Medicine and theUniversity of California, Irvine. The findings are published onlinethis week in the Proceedings of the National Academy of Sciences(PNAS). Mitochondrial DNA, which is separate from nuclear DNA, is foundin the hun...

A slight difference and significant similarities

There is little difference between the composition of the genetically produced potatoes known as fructan potatoes and that of conventionally bred varieties. They only differ in the new substances intentionally incorporated with gene technology. This conclusion has been reached by scientists at the Max Planck Institute of Molecular Plant Physiology and their colleagues from the University of Wales...

Sleeping beauty plays a significant role in identifying cancer genes

Researchers at the University of Minnesota Cancer Center and the National Cancer Institute (NCI), part of the National Institutes of Health, have discovered a new method that could accelerate the way cancer-causing genes are found and could lead to a more accurate identification of the genes, according to two studies in the July 14, 2005, issue of Nature. The gene identification method was...

Progress on HIV/AIDS significant but insufficient

United Nations Secretary-General Kofi Annan shared his hope with a gathering of senior world officials at Headquarters that the 2001 Declaration of Commitment on HIV/AIDS would have heralded a response that matched the epidemic's scale, yet progress had been "significant but insufficient". Citing achievements in the core areas of political leadership, funding, the intensity and reach of pr...

Delaware scientists make significant advance in study of small RNAs

Scientists from the University of Delaware have made a significant advance in the study of small ribonucleic acids (RNAs), discovering 10 times more small RNAs in the plant Arabidopsis than previously had been identified. The advance is reported in the Sept. 2 issue of Science magazine. The research was conducted over the course of the last year and a half by teams from the laboratories he...

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Emerging technology companies receive significant funding

Good news for some of Madisons emerging technology companies as they received significant funding this past week. These investments and grants will help to accelerate the growth of these high tech firms. Alfalight, a UW-Madison spinout company that manufacturers high-powered laser devices, announced that they have received nearly $6 million in military funding. Meanwhile, another UW-spinout eMet...

Genzyme acquistion of Bone Care approved, significant impact forecast

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Tattoos may significantly increase risk of hepatitis C infection

It is a fad these days to sport tattoos. Kids often show off their sticker tattoos. But adults go a step further. Permanent tattoos, which are permanent reminders throughout life, in different designs and shapes, are very popular. However there is a darker side to the whole affair. The study in the United States of America says that tattoos significantly increase the risk of hepatitis C infe...

A Little Weight Loss Found To Make A Significant Difference In Men

About 30 million men in the United States suffer from erectile dysfunction. This causes a decrease in quality of life for men. With exercise and weight loss // , obese men with erectile dysfunction may be able to improve their sexual function say researchers. Researchers, conducted a study to determine if lifestyle changes, such as losing weight and an increase in physical activity, woul...

Just one cigarette could cause significant damage

Researchers at Trinity College, Dublin, Ireland, have found from a recent study that there is an acute increase in arterial stiffness after smoking even one cigarette in both chronic and non-smokers. The researchers compared acute and chronic effects of smoking on large artery properties in 185 healthy young smokers and non-smokers aged 22 ± 5 years. 116 non-smokers// were compared with 41 chroni...

Inhaled Corticosteroids Found To Have No Significant Effect On COPD

COPD or chronic obstructive pulmonary disease is a disease caused by persistent obstruction of the airways // and is associated with severe emphysema or chronic bronchitis. Previous studies have shown inhaled corticosteroids can reduce the mortality rate and number of exacerbations COPD patients experience. However, results from a study conducted by researchers from the University of Washington s...

New Drug Shows Significant Improvement In HIV-related Heart Condition

Latest research has shown that treatment with the oral drug bosentan (Tracleer) has led to significant improvements in an often fatal disease, pulmonary arterial hypertension ( PAH) // . PAH is usually linked with human immunodeficiency virus infection. HIV infection is believed to cause the overproduction of endothelin, which increases the chance for small pulmonary arteries to become o...

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Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis

- Multinational Phase III Study Meets Primary Endpoint inRheumatoid Arthritis Patients Who Failed to Respond to Anti-tumorNecrosis Factor Treatments - NUTLEY, N.J., July 10, 2007 /PRNewswire/ -- Roche todayannounced that results from the Actemra Radiate (RheumAtoiDArthritIs Study in Anti-TNF FailurEs) trial successfully met itsprimary endpoint in patients with moderate to severe rheumatoi...

TMC125 Showed Significant Virologic Response at Week 24 in Treatment-Experienced HIV Patients With NNRTI Resistance in Phase 3 Trials

Data Published in The Lancet on TMC125, an Investigational NNRTIfrom Tibotec YARDLEY, Pa., July 05, 2007 /PRNewswire/ -- Data from twoongoing Phase 3 studies (DUET-1 and DUET-2) showed significantlymore HIV-1 adult patients with documented non-nucleoside reversetranscriptase inhibitor (NNRTI) and protease inhibitor (PI)resistance reached an undetectable viral load (defined as achievingco...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

CHICAGO--(BUSINESS WIRE)--Jun 23, 2007 - Late breaking datapresented at the American Diabetes Association (ADA) 67th AnnualScientific Sessions showed that, when used investigationally asinitial therapy, JANUVIA(TM) (sitagliptin) in combination withmetformin provided significant glycemic improvement and wasgenerally well tolerated over 54 weeks in patients with type 2diabetes. Additional new...

DiObex Presents Phase 2a Data of DIO-902 Demonstrating Trends of Improved Glycemic Control and Significant Reductions of LDL-Cholesterol and C-Reactive Protein

Top Line Data for the Treatment of Type 2 Diabetes Presented at the67th Annual Scientific Sessions of American Diabetes Association SAN FRANCISCO, June 25, 2007 /PRNewswire/ -- DiObex, Inc., aprivately-held biopharmaceutical company focused on the developmentof therapeutics to treat metabolic diseases, today announced thepresentation of top line data of its phase 2a study of DIO-902, afir...

Neurologix Announces Publication of Landmark Gene Therapy Study Demonstrating Safety and Statistically Significant Improvement in Patients With Advanced Parkinson's Disease

FORT LEE, N.J.--(BUSINESS WIRE)--Jun 21, 2007 - Neurologix, Inc.(OTCBB:NRGX) today announced the publication in the June 23 issueof the journal The Lancet of positive results from the first evergene therapy trial for Parkinson's disease and the first report ofdirect gene transfer into a patient's own brain cells for any adultneurodegenerative disease. The open label Phase 1 study, conduct...

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