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Shuts in Medical News

Colon cancer shuts down receptor that could shut it down

AUGUSTA, Ga. Though a high-fiber diet has long been considered good for you and beneficial in staving off colon cancer, Medical College of Georgia researchers have discovered a reason why: roughage activates a receptor with cancer-killing potential. Researchers report in the April issue of Ca...

Ozone shuts down early immune response in lungs and body

DURHAM, N.C. As policy makers debate what levels of ozone in the air are safe for humans to breathe, studies in mice are revealing that the inhaled pollutant impairs the bodys first line of defense, making it more susceptible to subsequent foreign invaders, such as bacteria. While it has lon...

Wellington Rest Home Shuts Down Due To Norovirus Outbreak

An outbreak of the contagious norovirus stomach bug has forced part of a Wellington based Rita Angus Retirement home, which has around 160 residents to shut down. It has// closed its communal facilities after the bug hit it. Norovirus, found in the faeces and vomit of infected people can spread...

Strep B Seems to Trick Immune System

...t of sepsis, meningitis in newborns MONDAY, July 13 (HealthDay News) -- A bacterial pathogen that causes sepsis and meningitis in newborns shuts down immune cell function to ensure its survival, a new study shows. The findings about Group B Streptococcus (GBS) may help lead to new drugs for ...

Odd Behaviors on Ambien Linked to Brain Circuitry

... When the sleep aid shuts down one set of neurons, another set wakes up: stu...al Center in Washington, D.C., found that zolpidem shuts down some powerful brain circuits but activates ot..." she explained. While it appears that zolpidem shuts down active neural pathways and perhaps triggers a...

The vulnerable cancer cell

... To do so, they introduce a short segment of RNA that looks like one of the cell's normal genes. The RNA interference machinery grinds into action and shuts down production of the protein made from that gene. Gilliland's team, which included first authors, Claudia Scholl and Stefan Frhling, as well as H...

By shutting down inflammation, agent reverses damage from spinal cord injury in preclinical studies

...e know the biological target, a new drug could be designed that is better suited for clinical treatment of these neurodegenerative disorders." CHPG shuts down activation of key immune cells in the brain known as microglia, which sense pathogens or damage in the spinal cord and brain. They helpfully fost...

American Association for Homecare Applauds President Obama's Plan to Aid Small Businesses

...current 'competitive' bidding initiative in Medicare is a proposal that actually reduces competition, reduces access to quality care for patients, and shuts out thousands of home medical equipment providers -- many of which are small businesses," said American Association for Homecare President Tyler J. Wi...

Seattle's First Bald Girls Do Lunch(R)

...etails at http://www.baldgirlsdolunch.org for online payment information. Alopecia areata is considered to be autoimmune, meaning that the body shuts down its own hair follicle function. With few acceptable treatments for advanced cases Chassin favors pro-active strategies for feeling whole today ov...

Sleepless in Botswana

...ynchronize your breathing with the blue wave, its movement becomes slower and slower. After a short time, you roll over and fall asleep and the device shuts off. The device utilizes an all natural, ancient deep breathing technique borrowed from yoga and meditation. The technique moderates the involunt...
Shuts in Medical Technology

Potentia Pharmaceuticals' POT-4 Drug Candidate for Age-Related Macular Degeneration Successfully Completes Phase I Clinical Trial - Prepares for Phase II

... it." About POT-4 POT-4 is a complement factor C3 inhibitor, which shuts down the complement activation cascade that could otherwise lead to local i...ent of all major complement activation pathways, its inhibition effectively shuts down downstream complement activation that could otherwise lead to local in...

Potentia Pharmaceuticals Announces Positive Safety Data and Study Expansion in Phase I Trial for Lead Drug Candidate POT-4

...icipation in the complement activation cascade. As C3 is the central component of all major complement activation pathways, its inhibition effectively shuts down downstream complement activation that could otherwise lead to local inflammation, tissue damage and upregulation of angiogenic factors such as va...

Release of Cytopia Abstract for CYT997 Oral Presentation at American Society of Clinical Oncology

...ts more than 30,000 delegates from around the world. About CYT997 CYT997 is a vascular disrupting agent (VDA) with a dual mechanism of action that shuts down established blood vessels supplying the tumor with nutrients and oxygen as well as being a general cytotoxic agent. The compound, which was disco...

OXiGENE Abstracts Published in ASCO Program

...The drug candidate has demonstrated single-agent activity in human tumor xenograft models. Preclinical research with OXi4503 suggests that it not only shuts down tumor blood flow, but can also be metabolized into a compound which could assist with killing the remaining tumor cells at the periphery of the t...

Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension

...h a cascade of biological events, renin acts to bring about sodium retention, an increase in blood pressure, and restoration of renal perfusion, which shuts off the signal for renin release. For hypertensive individuals, renin inhibitors are currently being investigated as a therapy that may provide benefi...
Shuts in Medical Products

Digistim 2 Plus Nerve Stimulator

Description:...y voltage is low. Pulse LED (red) flashes and audible indicator sounds each time a stimulus pulse is generated and before the instrument automatically shuts down. The loudness of the beep is adjustable.. Case: High-impact ABS plastic with anodized aluminum front and rear panels. Switches and handles are ...
Company:CCR Medical

Digistim 3 Plus Nerve Stimulator

Description:...ounds each time a stimulus pulse is generated. Audible indicator beeps each time a stimulus pulse is generated and before the instrument automatically shuts down. The loudness of the beep is adjustable. Power Source: 9-V alkaline battery (access door on rear panel) Power Consumption: Approximately 2.4...
Company:CCR Medical

Physio-Stim Bone Growth Stimulator

Features:... Patient friendly, comfortably worn during daily activities with or without a cast or brace, three hours per day LCD treatment countdown clock shuts off automatically when treatment is complete ...
Company:Orthofix, Inc
Shuts in Medical Dictionary

Toxin

...oxin gene expression. Two previous ... Researchers have demonstrated that a bacterial toxin from the common bacterium Staphylococcus aureus shuts down the control mechanism of the tunnel, called an ion ... Physician reviewed botulinum toxin type A patient information - includes botulinum ...

Lactic acid

...s get higher when strenuous exercise or other conditions—such ... You've probably heard that lactic acid is a waste product that burns and shuts ... Your goal should be to burn lactic acid more effectively, not produce less of it. ... Lactic Acid - You Can't Win Without ItLactic ...

Immune System

...The immune system rallies its defenses from the cellular level, everywhere in ... there is an excess of suppressor cells and the immune system shuts down. ... When the immune system is functioning properly, it protects the body against ... If the immune system weakens, its ability to de...

Anesthesia

...u from feeling pain during surgery and other medical or dental procedures. 4) Getting ready for surgery and anesthesia . ... Anesthesia shuts down neurologic mechanisms which convey sensory information. ... Patient information on the three main types of anesthesia : local, regional, and...
Shuts in Biological News

Study identifies brain pathway that shuts down seizures

Researchers at the University of Iowa and the Veterans Affairs Iowa City Health Care System have uncovered a brain pathway that shuts down seizures. The multidisciplinary team of scientists pieced together information from clinical observations made in the first half of the 20th century with k...

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

... DC Cancer researchers at Georgetown University's Lombardi Comprehensive Cancer Center have successfully tested a small, engineered antibody they say shuts down growth of human glioblastoma tumors in cell and animal studies. Glioblastoma is the deadliest of brain cancers; there is no effective treatment. ...

Study by NTU professors provides important insight into apoptosis or programmed cell death

...eus. Hence, when the concentration of RanGTP is reduced in the nucleus, the RanGTP gradient collapses and the nuclear transport machinery subsequently shuts down. Too little or too much apoptosis plays a role in a great many diseases. When programmed cell death does not work right, cells that should be ...

The battle for CRTC2: How obesity increases the risk for diabetes

...ionthe more ATF6a is bound to CRTC2, the less there is for CREB to bind to. "This clever mechanism ensures that a cell in survival mode automatically shuts down glucose production, thus saving energy," says Wang. This observation led the researcher to ask what happens to ATF6a following the kind of per...

Some short-term memories die suddenly, no fading

...ressively weaker as the battery runs low," Luck said. "They are more like a laptop computer that continues working at the same speed until it suddenly shuts down." This could be important in everyday life, he explained, because it would provide a mechanism to help us avoid the confusion that might arise if...

Gene linked to lupus might explain gender difference in disease risk

...c implications, said Dr. Chandra Mohan, professor of internal medicine and senior author of the study. "Our work also shows that blocking IRAK1 action shuts down lupus in an animal model. Though many genes may be involved in lupus, we only have very limited information on them," he said. The study appea...

Researchers find nature's shut-off switch for cellulose production

... WEST LAFAYETTE, Ind. - Purdue University researchers found a mechanism that naturally shuts down cellulose production in plants, and learning how to keep that switch turned on may be key to enhancing biomass production for plant-based biofuel...

Ship-in-a-bottle kit on a microchip

...el to the chip. In the same way, the researchers in Stuttgart roll a cog wheel through a channel with a serrated wall. The cog wheel, which completely shuts the channel off, agitates liquid back and forth and only in combination with two valves, acts like a pump. "Compared to other approaches to equippi...

Brown chemist finds gray mold's killer gene

...the central gene the fungus uses for this synthesis. They also have also shown that shutting off this gene by interrupting the fungus's DNA completely shuts down toxin production, removing the special weapon the mold uses to kill and invade target plant cells. "It's a big step to being able to disarm th...

2 new compounds show promise for eliminating breast cancer tumors

.... But in breast cancer patients, the protein is abnormally active. It never shuts off." When that happens, the protein goes into overdrive and is bent on ...lop. The network of blood vessels that formed to feed the cancer cells also shuts off. Left without their source of food, the existing cancer cells die o...
Shuts in Biological Technology

Solon Manufacturing Company Acquires PurFybr Brands; Adds Influenza Virus Diagnostic Swabs to Product Line

...s to meet all current and future PurFybr orders and has scheduled the transfer of equipment and inventory during the two-week period PurFybr typically shuts down each year. The PurFybr production facility will close today. Following the move to its state-of-the-art ISO 13485: 2003 FDA-registered facility ...

Potentia Pharmaceuticals Appoints Johanna M. Seddon, M.D. and Janet Stoltz Sunness, M.D. to Scientific Advisory Board

...icipation in the complement activation cascade. As C3 is the central component of all major complement activation pathways, its inhibition effectively shuts down downstream complement activation that could otherwise lead to local inflammation, tissue damage and upregulation of angiogenic factors such as va...

Potentia Pharmaceuticals' Drug Candidate for Age-Related Macular Degeneration Shows Positive Safety Profile in Phase I Clinical Trial

...ontinue this trial." About POT-4 POT-4 is a complement inhibitor, which shuts down the complement activation cascade that could otherwise lead to local i...ent of all major complement activation pathways, its inhibition effectively shuts down downstream complement activation that could otherwise lead to local in...

Potentia Pharmaceuticals to Present ASaP Phase I Clinical Trial Data for POT-4 at the American Academy of Ophthalmology Annual Meeting

...ent the data on Potentia's behalf. POT-4 is a complement inhibitor, which shuts down the complement activation cascade that could otherwise lead to local i...ent of all major complement activation pathways, its inhibition effectively shuts down downstream complement activation that could otherwise lead to local in...

New yeast trick for eating favorite food: Details in Nature paper

...ulation provides cells with an additional level of control over phenotypic expression. The UCSD team demonstrated that the glucose network actively shuts down the galactose network by degrading messenger RNA that would otherwise go on to form the enzymes needed to metabolize galactose. "To find somet...

We are American No sex, please

... New standard Today we might take the open links of the Internet as a symbol of freedom, yet the rest of the globe hates the contents, withdraws and shuts out all new ideas. Also, now the newly acclaimed morality standard of America must fully realign itself with the messages and their deliveries to t...

UW-Madison spinoff Pedrus finds more to business planning than good science

...unders Curtis Brandt and Hansi Dean, both UW-Madison researchers, are developing two drugs based on antiviral peptides discovered in Brandt's lab. One shuts down respiratory viruses such as flu, while the other targets some sexually transmitted viruses such as HIV and herpes. The emphasis is on preventi...

A new tool for keeping computers cool

...large amount of thermal energy in a very small spot, the temperature becomes very, very high, to the point where materials begin to deform or the chip shuts down completely," says Shedd. One of the most promising ways to combat this is spray cooling. In current designs, arrays of miniature nozzles with...

Got bugs? New project lets real computer users gang up on software bugs

...m averages just under 3,000 new reports per month, and bug rates vary a great deal across applications, he says, with "crash rates" (where the program shuts down) as high as 8 percent in one application to a low of 0.4 percent in another. All in all, his "kill board" has recorded 546 outright program crash...

Eppendorf Mastercycler ABI Big Dye Sequencing Protocol

...e control Heated lid temperature Program starts immediately Lid shuts off at end of program As instructed in Pharmacias Cycle S...
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