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Sequences in Medical News

CSHL scientists are part of consortium that sequences platypus genome

By any account, the platypus is an odd creature. Its got a broad, rubbery bill that brings to mind a duck.but it swims more like a beaver.yet it lays eggs and can inject poisonous venom, like a reptile. No wonder it was considered an elaborate hoax by scientists who examined the first specimen p...

454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It

BRANFORD, Conn., Sept. 27 /PRNewswire/ -- 454 Life Sciences, a Roche company, today reported that researchers from Pennsylvania State University have used the company's Genome Sequencer(TM) FLX system to sequence the entire mitochondrial genomes from 10 individual woolly mammoths. The study, e...

Important new model shows how proteins find the right DNA sequences

Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes. The findings are being published today in the scient...

New test for safer biomedical research results

...previously available commercial mycoplasma tests. McCT results are reproducible to 99.6 percent. The method is based on multiplication of specific DNA sequences by polymerase chain reaction and subsequent detection of the multiplied DNA regions. A special advantage of the new test is that it can be carried out...

Study Shows a Link Between Schizophrenia & Genetic Mutations

...X-linked mental retardation, neurological diseases and cancer, suggesting wide ranging involvement of miRNAs in disease. In this study, the sequences of 59 miRNA genes on the X-chromosome were determined in 193 men with schizophrenia and 191 without the disease. Men were chosen because they are much...

Cepheid Receives FDA Clearance for First On-Demand Molecular Diagnostic Test for Clostridium difficile Infection

...ons for fully integrated and automated nucleic acid analysis. The system is designed to purify, concentrate, detect and identify targeted nucleic acid sequences thereby delivering answers directly from unprocessed samples. Modular in design, the GeneXpert System has a variety of configurations to meet the broa...
Sequences in Medical Technology

Cepheid Receives Grant to Develop Ten-Color Real-Time PCR Detection Technology for Use in the GeneXpert(R) System

...ns for fully integrated and automated nucleic acid analysis. The system is designed to purify, concentrate, detect, and identify targeted nucleic acid sequences thereby delivering answers directly from unprocessed samples. Modular in design, the GeneXpert System has a variety of configurations to meet the broa...

Siemens Corporate Research Develops RAPID2 System for Fast Discovery of Discriminative Pathogen Signatures

...y from the outset." SCR used its new system recently to quickly discover a DNA barcode for detecting the H1N1 Flu after they received the genomic sequences of the virus isolated from infected patients from the National Institute of Health (NIH). In addition to applications related to healthcare-ass...

Mutant Genes in High-Risk Childhood Leukemias Identified

...ion, triggering the uncontrolled proliferation of white blood cells that is seen in leukemia." Thus, the researchers began to analyze the genetic sequences of many kinases known to be components of the proliferation machinery of white blood cells. The team analyzed the leukemic cells from 187 patients wit...

Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin

...ons for fully integrated and automated nucleic acid analysis. The system is designed to purify, concentrate, detect and identify targeted nucleic acid sequences thereby delivering answers directly from unprocessed samples. Modular in design, the GeneXpert System has a variety of configurations to meet the broa...

Adlyfe Strikes Translational Medicine Partnership With Wyeth Pharmaceuticals for Alzheimer's Biomarker Assay

...y is based on the synthesis of small peptides, or Pronucleon(TM) peptides, that are amino acid sequence matched to target amyloids of interest. Ligand sequences are selected based on regions of the target protein known to undergo conformational changes (structural changes in shape) associated with amyloid aggr...

Cloned Human Embryos Successfully Reprogrammed Using Human - But Not Animal - Eggs

...at DNA methylation/demethylation of the donor DNA occurs in a species-specific way, and that the eggs might lack the ability to demethylate repetitive sequences from other species. While cleavage division relies on maternal factors in the egg, further development requires activation of the embryonic genome to ...
Sequences in Medical Products

MGB Alert Norovirus 1 & 2 ASR*

Description:...abs more powerful tools for detecting nucleic acid sequences of specific organisms or genetic mutations associa...sease, as well as enabling labs to probe molecular sequences that may not be accessible with other technologies...* for the detection of various pathogens including sequences associated with BK virus, Enterovirus, VZV and oth...
Company:Nanogen, Inc.

NGEN RVA ASRs*

Description:... Nanogen offers reagents to detect sequences of the following viruses: human parainfluenza virus 1, 2 and 3; influenza virus A and B; and respiratory syncytial virus A and B. Laboratories may u...
Company:Nanogen, Inc.

MGB Alert HHV-6 ASR*

Description:...abs more powerful tools for detecting nucleic acid sequences of specific organisms or genetic mutations associa...sease, as well as enabling labs to probe molecular sequences that may not be accessible with other technologies...* for the detection of various pathogens including sequences associated with BK virus, Enterovirus, VZV and oth...
Company:Nanogen, Inc.

MGB Alert Mycoplasma pneumoniae ASR*

Description:...abs more powerful tools for detecting nucleic acid sequences of specific organisms or genetic mutations associa...sease, as well as enabling labs to probe molecular sequences that may not be accessible with other technologies...* for the detection of various pathogens including sequences associated with BK virus, Enterovirus, VZV and oth...
Company:Nanogen, Inc.

MGB Alert HSV 1, 2 Typer ASR*

Description:...abs more powerful tools for detecting nucleic acid sequences of specific organisms or genetic mutations associa...sease, as well as enabling labs to probe molecular sequences that may not be accessible with other technologies...* for the detection of various pathogens including sequences associated with BK virus, Enterovirus, VZV and oth...
Company:Nanogen, Inc.

NGEN HFE ASRs*

Description:...s for the detection of mutations associated with cystic fibrosis, thrombosis, and hereditary hemochromatosis, as well as reagents for the detection of sequences associated with several respiratory viruses. Nanogen offers reagents for detection of three mutations associated with Hereditary Hemochromatosis (HH)....
Company:Nanogen, Inc.
Sequences in Medical Definition

Personalized medicine

...lerating the realization of personalized medicine. The Personal Genome Project was announced by George Church in 2006; it will publish full genome sequences and medical records of volunteers in order to enable research into personalized medicine. Not only is personalized medicine tailoring the right dru...

Thymocyte

... The ability of T cells to recognise foreign antigens is mediated by the T cell receptor , which is a surface protein able to recognise short protein sequences ( peptides ) that are presented on MHC . During the double negative stage the major maturation step of thymocytes is to express a T cell receptor . ...
Sequences in Medical Dictionary

Psychology

...ogy Department wishes to acknowledge the contributions of ... Undergraduate Psychology Committee. Human Services and School Psychologist Course sequences ... is combining a major in psychology with a minor in management. ... symfony project ... Methods in Psychology . Psychological Research. The ...

Herpesvirus

.... In 199 4 a novel gamma herpesvirus was ... of human herpesvirus 8 infection ... Moore, PS, Chang, Y. Detection of herpesvirus -like DNA sequences in KS in ... FELINE HERPESVIRUS INFECTIONS ... In fact, most animals have their own type of herpesvirus . ... Herpesvirus is a common respir...

Genetics

...ity Program in Genetics and Genomics is an umbrella graduate ... Fungal Genetics ... As the science of genetics moved into the era of genome sequences and the ... societal impact and ethical implications of genetics research. ... Information about genetics and behavior --how is it studied, ...

Chromosomes

...24 human chromosomes and different genes that have been mapped to them. ... Finding a gene on a chromosome map. Accessing gene and protein sequences ... We are investigating how chromosomes are reorganized during this unique cell ... We have recorded large-scale chromosome movements durin...

Chromosome

...24 human chromosomes and different genes that have been mapped to them. ... Finding a gene on a chromosome map. Accessing gene and protein sequences ... Images of all 24 human chromosomes and different genes that have been mapped to them. ... Home Site Index Chromosome Viewer Genetic Diso...

Amnion

...amnion fluid, head movement, ... Supernatants of amnion fluid samples (in some cases concentrated by ... In 64 out of 238 amnion samples, DNA sequences of AAV were detected by PCR (Table IIA, ... ... externally is where ectoderm of amnion meets endoderm of yolk sac and ... externally as the ju...
Sequences in Biological News

Scientists decoding genomic sequences of H1N1 using isolates from outbreak in Argentina

July 30, 2009 -- Researchers at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health are working with Argentina's National Institute of Infectious Diseases, the National Administration of Laboratories and Health Institutes (ANLIS), and Roche 454 Life S...

Inconsistencies with Neanderthal genomic DNA sequences

Were Neanderthals direct ancestors of contemporary humans or an evolutionary side branch that eventually died out? This is one of the enduring questions in human evolution as scientists explore the relationship of fossil groups, such as Neanderthals, with people alive today. Two recent papers desc...

Genomic sequences processed in minutes, rather than weeks

A new computational tool developed at the Department of Energy's Pacific Northwest National Laboratory is speeding up our understanding of the machinery of life -- bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biologic...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

Amidst the hoopla over the exact number of genes we have in our genome—more than a fruitfly, fewer than a rice plant—a more fundamental genetic truth has often been obscured. The expression of 20,000?0,000 genes is under the control of an uncounted host of non-coding sequences, which bind transcrip...

Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols

...g Beauty transposon-based transfection is a two-component system consisting of a transposase and a transposon containing inverted repeat/direct repeat sequences that result in precise integration into a TA dinucleotide. The article is freely accessible on the website for Cold Spring Harbor Protocols ( http:/...

August 2009 Geology and GSA Today media highlights

...fluctuation, a time period in which southern Pangea saw the waxing and waning of massive continental ice sheets while low-latitude Pangean sedimentary sequences recorded multiple 100-m eustatic fluctuations. This cyclicity is thought to have been driven by changes in Earth's orbit with relation to the sun. Hor...
Sequences in Biological Technology

Selecting siRNA Sequences to Incorporate into the pSilencer Vectors

The first step in preparing a plasmid for siRNA experiments is to identify target sequences in the gene of interest that are susceptible to siRNA-induced degradation. We have found that a little more than half of the siRNAs provide at le...

Randomize Gene Sequences with New PCR Mutagenesis Kit

GeneMorph PCR mutagenesis kit produces a unique mutational spectrum Janice Cline Holly Hogrefe Stratagene ...

NimbleGen identifies human genome sequences

San Diego, Calif. Researchers at the Ludwig Institute for Cancer Research , using technology made by Madison-based NimbleGen Systems , have developed a method to identify thousands of regulatory sequences in the human genome, according to a study published today in Nature. The purpose of th...

SmartGene's Services for Faster, More Precise Identification of Bacteria and Fungi to be Used by The Johns Hopkins Hospital

... an organism's DNA, by integrating a number of tasks, including sequence editing, alignment, interpretation, creation of dendrograms and reports. DNA sequences are interrogated using SmartGene's broad, constantly updated reference databases, which take account of newly characterized and emerging pathogens. Sm...

Medicago's H1N1 pandemic vaccine candidate shows positive response in 100% of vaccinated animals after a single dose

...peed and cost over competitive technologies. It could deliver a vaccine for testing in about a month after the identification and reception of genetic sequences from a pandemic strain. This production time frame has the potential to allow vaccination of the population before the first wave of a pandemic strike...

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

...ative development activities in the fields of wound healing and cardiovascular disease, the Company has access to a portfolio of protein-producing DNA sequences that include Platelet Derived Growth Factor-B (PDGF-B), Insulin like Growth Factor-I (IGF-I) and Fibroblast Growth Factor-4 (FGF-4). In additi...
Sequences in Biological Products

APAgene Genome Walking Kit from Bio S&T

Description:...ents are provided in each kit. The Genome Walking Kit can be used for gap filling, localized cloning of genomic DNA, isolating promoter and regulatory sequences corresponding to cloned cDNAs, 5 and 3 RACE of first-strand cDNAs, identifying intron/exon junctions....
Company:Bio S&T

TRIMMER-Direct cDNA Normalization Kit from Evrogen JSC

Description:...cing projects, microarrays, functional screenings etc. The Evrogen TRIMMER-DIRECT kit is developed for normalization of cDNA enriched with full-length sequences and intended for directional cloning. While most normalization methods are not well suited for the normalization of long cDNA, TRIMMER-DIRECT allows t...
Company:Evrogen JSC

Gene Construction Kit™ 2.5 from Textco, Inc.

Description:... 'The Gene Construction KitTM allows graphic manipulation of DNA sequences and sophisticated plasmid drawing options. It has an award winning interface design that allows graphic manipulation of DNA sequences in addition to providing sophisticated drawing capabilities for Mac and Win...
Company:Textco, Inc.

Bacterial Strain BMH 71-18 mutS, Glycerol Stock (noncompetent) from Promega

Description:...s as the GeneEditor and Altered Sites II Mutagenesis Systems. Both ES1301 and BMH 71-18 mutS are recA+, therefore inserts containing highly repetitive sequences may be unstable. ES1301 is used in the Altered Sites II System and is Tets, which allows for cycling between antibiotic resistances. The BMH 71-18 is ...
Company:Promega

Bacterial Strain ES1301 mutS, Glycerol Stock (noncompetent) from Promega

Description:...s as the GeneEditor and Altered Sites II Mutagenesis Systems. Both ES1301 and BMH 71-18 mutS are recA+, therefore inserts containing highly repetitive sequences may be unstable. ES1301 is used in the Altered Sites II System and is Tets, which allows for cycling between antibiotic resistances. The BMH 71-18 is ...
Company:Promega

DeCypher Biocomputing Solutions from TimeLogic, a Brand of Active Motif, Inc.

Description:...ized queries (~250 kb) to genomic DNA Use HMM analysis to compare 100,000 sequences to PFAM in 5 hours Map cDNAs, ESTs or proteins to genomic data with GeneDetective Mask vector & repeat sequences using RepeatMasker Run cross-species protein comparisons with Smith-Waterm...
Company:TimeLogic, a Brand of Active Motif, Inc.
Sequences in Biological Definition

Apoptosis

...tle results in uncontrolled cell proliferation, as in cancerous tumors. Not all forms of PCD share the characteristic shapes (the morphology ) and sequences of apoptosis, but all types of PCD are highly regulated processes. Contents showTocToggle("show","hide") 1 Functions of apoptosis ...

Beta sheet

...uling and Robert Corey in 1951 . It consists of two or more amino acid sequences within the same protein that are arranged adjacently and in parallel, but w... the alternate side of the sheet are polar or charged (hydrophilic). Some sequences involved in a β sheet, when traced along the backbone, take a hairpin...

Biology

...generate information about phylogeny. These include the comparisons of DNA sequences conducted within molecular biology or genomics , and comparisons of fo...iology leans heavily on techniques from molecular biology to determine DNA sequences which assist in understanding the genetic variation of a population; and p...

Bioinformatics

...biology include the assembly of high-quality DNA sequences from fragmentary "shotgun" DNA sequencing , and t...ount of data, it becomes impossible to analyze DNA sequences manually. Today, computer programs are used to find similar sequences in the genome of dozens of organisms, within bil...

BLAST

...LAST , is an algorithm for comparing biological sequences , such as the amino-acid sequences of different proteins or the DNA sequences . Given a library or database of sequences, a B...

Cell metabolism

...ucture; and catabolism , in which a cell breaks down complex molecules to yield energy and reducing power. Cell metabolism involves extremely complex sequences of controlled chemical reactions called metabolic pathways . Contents showTocToggle("show","hide") 1 Anabolism 2 Catabolism ...
Sequences in Biological Dictionary

Tandem repeat sequences

... Computer Science, tandem repeats in strings (e.g. DNA sequences ) can be ... (Long terminal repeat , SINEs, LINEs) · Genomic island · Alu sequence ... A short tandem repeat (STR) in DNA occurs when a pattern of two or more nucleotides are repeated and the repeated sequences...

Insertion sequences

An insertion sequence is a short DNA sequence that acts as a simple transposable element. Insertion sequences have two major characteristics: they are small relative to other transposable elements and only code for proteins implicated in the transposition activity .... Article on t...

Complementary sequences

Complementary sequences (CS) are defined as pairs of sequences with the useful property that their out-of-phase aperiodic autocorrelation coefficients sum to zero. Binary complementary sequences were first introduced by Marcel J. E. Golay in 1949. In 1961–1962 Golay... In molecular biology...

Z-DNA

...form Z-DNA . ... R. M. Wing, A. V. Fratini & M. L. Kopka (1982) The anatomy of A-, B-, and Z-DNA . ... Left-handed Z-DNA can be formed by sequences containing alternating purine ... Under physiological conditions, Z-DNA formation is a dynamic process, largely ... Twenty years after visualiz...

Zinc finger

...ymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target desired DNA sequences which enables zinc - finger nucleases to target unique... zinc finger ( ¦ziŋk ¦fiŋgər ) ( biochemistry ) A small structural domain that i...

Xenopus

...m. Find Great Bargains on Sporting Goods, Toys, Collectibles, Car Parts, Food, and the Good Things in Life. Provides vector information, primer sequences and library information for this frog arranged by tissue. ... 8. RIKEN Xenopus egg. 9. Soares NXEG. 10. Wellcome ... Xenopus Full-Length cDNA...
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