Vanderbilt researchers pioneer an advanced sepsis detection and management system
When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread. Martin, who is a fellow in allergy, pulmonary ...Medical Simulation Corporation Introduces Sepsis Quality Initiative Program
DENVER, Oct. 28 /PRNewswire/ -- Medical Simulation Corporation (MSC) announces the introduction of the SimSuite Sepsis Program, based on guidelines developed by the national Surviving Sepsis Campaign. The Sepsis Program is one offering in a full menu of SimSuite education solutions that addres...Customized treatments for sepsis lower treatment time and reduce length of ICU stays
Using a blood test and a decision algorithm, rather than standard hospital protocols, to determine the appropriate length of antibiotic therapy in patients with severe sepsis or septic shock can reduce duration of treatments, shorten ICU stays, and lower hospital costs all without adverse effects ...Educational Drive Cut Death Rate From Sepsis
Spanish hospital effort led to better guideline adherence, earlier use of antibiotics for blood infection TUESDAY, May 20 (HealthDay News) -- A national education program in Spain to promote appropriate care for severe sepsis (bloodstream infection) and septic shock led to improved gui...Ashwell receptor reduces mortality during sepsis
In research that solves the longest-standing mystery in glycobiology a field that studies complex sugar chains called glycans researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is cri...Research May Yield New Weapons Against Sepsis
The severe blood infection kills more than 33,000 Americans per year, experts say WEDNESDAY, Feb. 27 (HealthDay News) -- U.S. researchers say they've spotted several potential new drug targets for the serious blood infection known as sepsis. Sepsis, caused by a bacterial infection t...Blacks More Likely to Die of Severe Sepsis
Analysis shows they're twice as likely as whites or Hispanics to develop condition FRIDAY, Feb. 8 (HealthDay News) -- Black Americans are almost twice as likely to develop severe sepsis than whites and are more likely to die of severe sepsis than either whites or Hispanics, new researc...New Sepsis Model may Improve Patient Care
A new mathematical model of sepsis can help predict deaths, discharges, and disease progression in hospital patients with this serious bacterial blood infection.This will help clinicians assess which interventions are likely to be best for their patients. Mark S. Roberts and colleagues fro...Drexel Research in Cytokines Could Treat Sepsis
Researchers from Drexel University and the University of Brighton in the U.K. have achieved groundbreaking results, which may significantly improve the treatment of sepsis. // Sepsis is an uncontrolled immune response to infection or severe trauma that results in 1,500 deaths worldwide ever...Researchers identify the early makers of Neonatal Sepsis
Neonatal sepsis had been one of the dreaded forms of disease with very high mortality even in the best of centers. One of the reason for such a catastrophe is that the condition is diagnosed relatively a bit late. Neonatal sepsis always is both a diagnostic as well as therapeutic challenge to the p...Sirius Genomics Announces New Collaboration with Assistance Publique-Hopitaux de Paris
...is (AP-HP) to study genomic correlations in severe sepsis patients. The agreement focuses on the continued d... the trademark Xigris (R)) in patients with severe sepsis at high risk of death. "Access to AP-HP's severe sepsis patients will be critical in the validation of Sir...Key protein regulating inflammation may prove relevant to controlling sepsis
Scientists at Singapore's Institute of Molecular and Cell Biology (IMCB), under the Agency for Science, Technology and Research (A*STAR), have identified the protein, WIP1, as the molecular "brake" that curbs severe inflammation in the body. The findings may prove relevant to developing m...In the laboratory, green tea proves a powerful medicine against severe sepsis
MANHASSET, NY A major component of green tea could prove the perfect elixir for severe sepsis, an abnormal immune system response to a bacterial infection. In a new laboratory study, Haichao Wang, PhD, of The Feinstein Institute for Medical Research, and his colleagues have been studying the ther...Study begins to reveal clues to the cause and progression of sepsis
PITTSBURGH, Aug. 13 Not all patients with sepsis mount the same immune response, even when they look the same clinically, according to findings from the first large-scale natural history study of sepsis. The results, published by University of Pittsburgh School of Medicine researchers in the Augu...New study aims to stop sepsis in its tracks
If you've had a heart attack or stroke, paramedics, doctors, and nurses follow standardized protocols for what to do right away, and their efforts improve your odds for a full recovery. That's not the case if you have a body-wide infection known as sepsis, which can be fatal within a few hours and ...Mayo Clinic researchers challenge sepsis theory
A Mayo Clinic research team has challenged the accepted theory on the cause of sepsis -- a condition in which the body's cells generate fever, shock and often death. Sepsis is thought to occur when poisons from bacterial infection interfere with the cells. The Mayo researchers challenge that long...Scientists uncork a potential secret of red wine's health benefits
...nitis, and systemic sepsis. "Strong acute inflammatory diseases such as sepsis are very difficult to treat and many die every day due to lack of treatment... one of the researchers involved in the work. "Moreover, many survivors of sepsis develop a very low quality of life due to the damage that inflammation caus...Older men more likely than women to die after pneumonia
...he multicenter Genetic and Inflammatory Markers of sepsis (GenIMS) study. Participants were enrolled upon em...ndition, such as cardiac disease or cancer. Severe sepsis occurred in 588 (31 percent) subjects. Of these, about half had severe sepsis on their first day of hospitalization. Men had...Sugar on bacteria surface serves as base for a web of resistance
...that can foster creation of the biofilm. Some critically ill hospitalized patients also are susceptible to infection by Pseudomonas, which can lead to sepsis or bacteremia, common causes of death in very sick intensive-care patients. With Psl clearly identified as the foundation of the matrix, or the ar...Research could lead to new non-antibiotic drugs to counter hospital infections
...t. Once the host is weakened by an illness, surgical procedure or immunosuppressive drugs, however, P. aeruginosa can cause infection, inflammation, sepsis and death. Why P. aeruginosa can suddenly turn on its host has eluded researchersuntil now. Scientists have long known that after an operation o...Children's National research links platelets to sepsis-related organ failure
...ces over the last few decades, mortality rates for sepsis have not really improved," said Robert Freishtat,...risk of dying and to design new interventions." sepsis is the tenth leading cause of death in the United States. More than 40 percent of sepsis cases are fatal, and in most, the resulting organ ...Spectral signs exclusive license agreement to bring sepsis therapeutic to the U.S. market
TORONTO, March 9 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI) today announced that it has signed a license agreement with Toray Industries, Inc. of Japan granting Spectral the exclusive development and commercial rights in the U.S. for Toraymyxin(TM), a therapeutic device for the t...Spectral's EAA(TM) to be used in Phase III study for a sepsis anti-endotoxin therapy
TORONTO, April 9 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX: SDI) today announced that its Endotoxin Activity Assay (EAA(TM)), an FDA cleared diagnostic for risk of sepsis, will be used to measure endotoxin levels during the enrolment of patients in a Phase III sub study, part of ...Spectral partner launches EAA(TM) Rapid Sepsis Diagnostic in Germany
TORONTO, Sept. 20 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI) today announced the market launch of its EAA(TM) Endotoxin Activity Assay, a rapid diagnostic product for sepsis, in Germany through A. Menarini Diagnostics Deutschland ("Menarini"), a division of the Italian Menari...U.S. Clinicians Indicate a Strong Need for New Tools to Combat Sepsis
Survey shows hospital physicians, pulmonary and critical care clinicians, and researchers also concerned about overuse of antibiotics DURHAM, N.C., July 24 /PRNewswire/ -- bioMerieux recently conducted two surveys, fielded during conferences of the American Thoracic Society and Society of ...Sirius Genomics Announces 2009 Board of Directors
... assess responsiveness to recombinant human activated Protein C (sold by Eli Lilly and Company under the trademark Xigris (R)) in patients with severe sepsis at high risk of death. This release contains forward-looking statements that are not based on historical fact. These forward-looking statements i...Spectral announces first quarter 2009 results
...y in Europe and Japan, for the treatment of severe sepsis and has demonstrated a significant reduction in the mortality of patients with severe sepsis compared to standard of care. We believe that, whe...e growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being devel...