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Sepsis in Medical News

Vanderbilt researchers pioneer an advanced sepsis detection and management system

When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread. Martin, who is a fellow in allergy, pulmonary ...

Medical Simulation Corporation Introduces Sepsis Quality Initiative Program

DENVER, Oct. 28 /PRNewswire/ -- Medical Simulation Corporation (MSC) announces the introduction of the SimSuite Sepsis Program, based on guidelines developed by the national Surviving Sepsis Campaign. The Sepsis Program is one offering in a full menu of SimSuite education solutions that addres...

Customized treatments for sepsis lower treatment time and reduce length of ICU stays

Using a blood test and a decision algorithm, rather than standard hospital protocols, to determine the appropriate length of antibiotic therapy in patients with severe sepsis or septic shock can reduce duration of treatments, shorten ICU stays, and lower hospital costs all without adverse effects ...

Educational Drive Cut Death Rate From Sepsis

Spanish hospital effort led to better guideline adherence, earlier use of antibiotics for blood infection TUESDAY, May 20 (HealthDay News) -- A national education program in Spain to promote appropriate care for severe sepsis (bloodstream infection) and septic shock led to improved gui...

Ashwell receptor reduces mortality during sepsis

In research that solves the longest-standing mystery in glycobiology a field that studies complex sugar chains called glycans researchers at the University of California, San Diego School of Medicine have discovered that a molecule in the liver of all animals, called the Ashwell receptor, is cri...

Research May Yield New Weapons Against Sepsis

The severe blood infection kills more than 33,000 Americans per year, experts say WEDNESDAY, Feb. 27 (HealthDay News) -- U.S. researchers say they've spotted several potential new drug targets for the serious blood infection known as sepsis. Sepsis, caused by a bacterial infection t...

Blacks More Likely to Die of Severe Sepsis

Analysis shows they're twice as likely as whites or Hispanics to develop condition FRIDAY, Feb. 8 (HealthDay News) -- Black Americans are almost twice as likely to develop severe sepsis than whites and are more likely to die of severe sepsis than either whites or Hispanics, new researc...

New Sepsis Model may Improve Patient Care

A new mathematical model of sepsis can help predict deaths, discharges, and disease progression in hospital patients with this serious bacterial blood infection.This will help clinicians assess which interventions are likely to be best for their patients. Mark S. Roberts and colleagues fro...

Drexel Research in Cytokines Could Treat Sepsis

Researchers from Drexel University and the University of Brighton in the U.K. have achieved groundbreaking results, which may significantly improve the treatment of sepsis. // Sepsis is an uncontrolled immune response to infection or severe trauma that results in 1,500 deaths worldwide ever...

Researchers identify the early makers of Neonatal Sepsis

Neonatal sepsis had been one of the dreaded forms of disease with very high mortality even in the best of centers. One of the reason for such a catastrophe is that the condition is diagnosed relatively a bit late. Neonatal sepsis always is both a diagnostic as well as therapeutic challenge to the p...

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Sepsis in Medical Technology

Agennix Initiates A Randomized Double-Blind, Placebo-Controlled Phase 2 Study of Oral Talactoferrin in Severe Sepsis

Company also announces Award of a National Institutes of Health Small Business Innovative Research (SBIR) Grant to support the Phase 2 Trial HOUSTON, April 22 /PRNewswire/ -- Agennix, Inc. announced today that it has initiated a randomized, double-blind, placebo-controlled Phase 2 study of...

Sirius Genomics Announces New Collaboration with Assistance Publique-Hopitaux de Paris

...is (AP-HP) to study genomic correlations in severe sepsis patients. The agreement focuses on the continued d... the trademark Xigris (R)) in patients with severe sepsis at high risk of death. "Access to AP-HP's severe sepsis patients will be critical in the validation of Sir...

Great Basin Scientific, Inc. Raises $3.6 Million in Bridge Funding to Prepare for Launch of First Product

...HAIs) In addition to its first product for MRSA testing, the company is also developing tests for Group B Streptococcus - the most common cause of sepsis and meningitis in newborns, and Human Papilloma Virus (HPV), the most common sexually transmitted infection of which certain types can lead to cervica...

Two New Clinical Studies Show That Limited Exposure to Blood Transfusion Significantly Increases Morbidity and Mortality After Surgery

...ntraoperative transfusion of 1U to 2U of packed red blood cells is associated with increased 30-day mortality, surgical site infection, pneumonia, and sepsis in general surgery patients. Journal of the American College of Surgeons. 2009; 208:931-937. (2) Surgenor SD et al, for the Northern New Englan...

IMPACT Study Showed Longer Valcyte(R) (valganciclovir hydrochloride tablets) Treatment Demonstrated Better Protection Against Cytomegalovirus (CMV) Disease One Year Post-Transplant

...atment with Valcyte, occurred in the 100-day treatment group and took place in France, Belgium and Romania. They were attributed to hemorrhage (one), sepsis (one) or septic shock (two). About CMV CMV belongs to the family of herpes viruses and, as such, is very common among the general population...

Spectral presents data on the clinical utility of EAA(TM) at 13th Annual Critical Care for Endotoxemia conference in Japan

...ridge product in the United States." Debra Foster, Director of Spectral's sepsis Program, presented data on the use of EAA(TM) in the management of intra-abdominal sepsis following surgical intervention. Following the conference, these findings w...

Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer

...OXIL and/or VELCADE - Persistent severe myelosuppression may result in superinfection, neutropenic fever, or hemorrhage - sepsis occurring during neutropenia has resulted in discontinuation of treatment and in rare cases of death * DOXIL may potentiate the toxici...

Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome

...tions, 1% of which were Grade 3 or higher. The most common serious adverse reactions regardless of the relationship to the study drug were neutropenic sepsis (5.4% / 1.1% / 3.3%), neutropenic infection (5.4% / 4.3% / 8.8%), and febrile neutropenia (4.3% / 3.3% / 5.5%), pulmonary hemorrhage (1.1% / 3.3% / 0%...

Cepheid Molecular Diagnostic Test for Positive Blood Culture Bottles Categorized 'Moderate Complexity' by FDA

...pert MRSA/SA BC processes positive blood culture specimens to determine if a patient's blood is infected with MRSA or SA, which are frequent causes of sepsis in hospitalized patients. This may enable physicians to quickly de-escalate from broad-spectrum antibiotic treatment to a more effective targeted ther...

Continuous Treatment With Abbott's HUMIRA(R) Achieves Superior Long-Term Efficacy for Psoriasis Patients Compared to Interrupting Treatment

...tients with active infections until infections are controlled. HUMIRA should not be used by patients with active TB or other severe infections such as sepsis and opportunistic infections. If latent tuberculosis is diagnosed, appropriate treatment for latent tuberculosis must be initiated with anti-tubercu...
Sepsis in Medical Dictionary

Sepsis

Sepsis is a serious medical condition characterized by a whole-body inflammatory state and the presence of a known or suspected infection. The body may develop this inflammatory response to microbes in the blood, urine, lungs, skin, or other tissues. An incorrect... Information about the caus...

Septic shock

...ally Overview: Clinicians often use the terms sepsis and septic shock without a commonly understoo.... ... is a continuum of severity ranging from sepsis to severe sepsis and septic shock . ... Septic shock : Initi...

Septicemia

... sepsis is a serious medical condition characterized by a whole-body inflammatory s...mine was just diagnosed with septicemia . ... Septicemia " is a state of sepsis in which the organisms are also found in the blood. ... ...

Human bites

... Injuries from human bites , present a particular risk to other humans, with a major risk of sepsis from infection by human oral bacteria and the possibility of transmission of blood-borne diseases including, syphilis and hepatitis. How ...

Endocrinology

... 1 Principles of endocrinology . Functions of hormones and their regulation ... and autocrine regulation of blood pressure: the endocrinology of sepsis ... Guide to Nature Reviews Endocrinology . Online submission. Guidelines for referees ... Endocrinology . Gastroenterology & Hepatology. M...

Electrical shock

... electrical ... Electric Shock Treatment. Self-Care at Home. Medical ... Electric Shock . Insulin Reaction. Life-Threatening Skin Rashes. sepsis (Blood Infection) ... Diabetic Coma, Insulin Shock . Digestive System. Dislocations ... An electric shock occurs when a person comes into con...

Blood poisoning

... sepsis is a serious medical condition characterized by a whole-body inflammatory s...oning ; Bacteremia with sepsis. Causes, incidence, and risk factors ... sepsis ( blood poisoning ) can be a deadly infection. ... blood poisoning , s...
Sepsis in Biological News

Key protein regulating inflammation may prove relevant to controlling sepsis

Scientists at Singapore's Institute of Molecular and Cell Biology (IMCB), under the Agency for Science, Technology and Research (A*STAR), have identified the protein, WIP1, as the molecular "brake" that curbs severe inflammation in the body. The findings may prove relevant to developing m...

In the laboratory, green tea proves a powerful medicine against severe sepsis

MANHASSET, NY A major component of green tea could prove the perfect elixir for severe sepsis, an abnormal immune system response to a bacterial infection. In a new laboratory study, Haichao Wang, PhD, of The Feinstein Institute for Medical Research, and his colleagues have been studying the ther...

Study begins to reveal clues to the cause and progression of sepsis

PITTSBURGH, Aug. 13 Not all patients with sepsis mount the same immune response, even when they look the same clinically, according to findings from the first large-scale natural history study of sepsis. The results, published by University of Pittsburgh School of Medicine researchers in the Augu...

New study aims to stop sepsis in its tracks

If you've had a heart attack or stroke, paramedics, doctors, and nurses follow standardized protocols for what to do right away, and their efforts improve your odds for a full recovery. That's not the case if you have a body-wide infection known as sepsis, which can be fatal within a few hours and ...

Mayo Clinic researchers challenge sepsis theory

A Mayo Clinic research team has challenged the accepted theory on the cause of sepsis -- a condition in which the body's cells generate fever, shock and often death. Sepsis is thought to occur when poisons from bacterial infection interfere with the cells. The Mayo researchers challenge that long...

Scientists uncork a potential secret of red wine's health benefits

...nitis, and systemic sepsis. "Strong acute inflammatory diseases such as sepsis are very difficult to treat and many die every day due to lack of treatment... one of the researchers involved in the work. "Moreover, many survivors of sepsis develop a very low quality of life due to the damage that inflammation caus...

Older men more likely than women to die after pneumonia

...he multicenter Genetic and Inflammatory Markers of sepsis (GenIMS) study. Participants were enrolled upon em...ndition, such as cardiac disease or cancer. Severe sepsis occurred in 588 (31 percent) subjects. Of these, about half had severe sepsis on their first day of hospitalization. Men had...

Sugar on bacteria surface serves as base for a web of resistance

...that can foster creation of the biofilm. Some critically ill hospitalized patients also are susceptible to infection by Pseudomonas, which can lead to sepsis or bacteremia, common causes of death in very sick intensive-care patients. With Psl clearly identified as the foundation of the matrix, or the ar...

Research could lead to new non-antibiotic drugs to counter hospital infections

...t. Once the host is weakened by an illness, surgical procedure or immunosuppressive drugs, however, P. aeruginosa can cause infection, inflammation, sepsis and death. Why P. aeruginosa can suddenly turn on its host has eluded researchersuntil now. Scientists have long known that after an operation o...

Children's National research links platelets to sepsis-related organ failure

...ces over the last few decades, mortality rates for sepsis have not really improved," said Robert Freishtat,...risk of dying and to design new interventions." sepsis is the tenth leading cause of death in the United States. More than 40 percent of sepsis cases are fatal, and in most, the resulting organ ...
Sepsis in Biological Technology

Spectral announces publication demonstrating Toraymyxin(TM) significantly reduces mortality from sepsis in prospective controlled trial

TORONTO, June 18 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI), a company developing products for the treatment of sepsis, today announced that findings demonstrating the Toraymyxin(TM) cartridge, a blood purification device that absorbs endotoxin from the bloodstream, when added to...

Spectral signs exclusive license agreement to bring sepsis therapeutic to the U.S. market

TORONTO, March 9 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI) today announced that it has signed a license agreement with Toray Industries, Inc. of Japan granting Spectral the exclusive development and commercial rights in the U.S. for Toraymyxin(TM), a therapeutic device for the t...

Spectral announces exclusive distribution agreement in Russia for its EAA(TM) Sepsis Diagnostic Assay

TORONTO, July 10 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX: SDI) today announced that it has entered into a exclusive distribution agreement in Russia with BB Medical for Spectral's Endotoxin Activity Assay (EAA(TM)), the only FDA cleared assay for the measurement of endotoxin. U...

Spectral announces presentation of data on improving sepsis patient management with EAA(TM) and Toraymyxin(TM) combination

TORONTO, June 2 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX: SDI) today announced that data demonstrating the clinical utility of its EAA(TM) Endotoxin Activity Assay in combination with Toray Medical's therapeutic column, Toraymyxin, was presented at the Practical Aspects of Extra...

Spectral's EAA(TM) to be used in Phase III study for a sepsis anti-endotoxin therapy

TORONTO, April 9 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX: SDI) today announced that its Endotoxin Activity Assay (EAA(TM)), an FDA cleared diagnostic for risk of sepsis, will be used to measure endotoxin levels during the enrolment of patients in a Phase III sub study, part of ...

Spectral partner launches EAA(TM) Rapid Sepsis Diagnostic in Germany

TORONTO, Sept. 20 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI) today announced the market launch of its EAA(TM) Endotoxin Activity Assay, a rapid diagnostic product for sepsis, in Germany through A. Menarini Diagnostics Deutschland ("Menarini"), a division of the Italian Menari...

U.S. Clinicians Indicate a Strong Need for New Tools to Combat Sepsis

Survey shows hospital physicians, pulmonary and critical care clinicians, and researchers also concerned about overuse of antibiotics DURHAM, N.C., July 24 /PRNewswire/ -- bioMerieux recently conducted two surveys, fielded during conferences of the American Thoracic Society and Society of ...

Sirius Genomics Announces 2009 Board of Directors

... assess responsiveness to recombinant human activated Protein C (sold by Eli Lilly and Company under the trademark Xigris (R)) in patients with severe sepsis at high risk of death. This release contains forward-looking statements that are not based on historical fact. These forward-looking statements i...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...on of DOXIL and/or VELCADE Persistent severe myelosuppression may result in superinfection, neutropenic fever, or hemorrhage sepsis occurring during neutropenia has resulted in discontinuation of treatment and in rare cases of death DOXIL may potentiate th...

Spectral announces first quarter 2009 results

...y in Europe and Japan, for the treatment of severe sepsis and has demonstrated a significant reduction in the mortality of patients with severe sepsis compared to standard of care. We believe that, whe...e growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being devel...
Sepsis in Biological Definition

Bacterium

.... Some bacteria act as pathogens and cause tetanus , typhoid fever , pneumonia , syphilis , cholera , foodborne illness and tuberculosis . sepsis , a systemic infectious syndrome characterized by shock and massive vasodilation, or localized infection, can be caused by bacteria such as streptoco...

Blood

...rough blood contact. Owing to blood-borne infections, bloodstained objects are treated as a biohazard . Infection of the blood is bacteremia or sepsis . Malaria and trypanosomiasis are blood-borne parasitic infections. Treatment Blood transfusion is the most direct therapeutic use of bl...

Bacterium

.... Some bacteria act as pathogens and cause tetanus , typhoid fever , pneumonia , syphilis , cholera , foodborne illness and tuberculosis . sepsis , a systemic infectious syndrome characterized by shock and massive vasodilation, or localized infection, can be caused by bacteria such as streptoco...

Redox

...rconversion is dependent on these ratios. An abnormal redox state can develop in a variety of deleterious situations, such as hypoxia , shock , and sepsis . See also Bioremediation Calvin cycle Citric acid cycle Electrochemistry Galvanic cell External link Redox...

Redox

...rconversion is dependent on these ratios. An abnormal redox state can develop in a variety of deleterious situations, such as hypoxia , shock , and sepsis . See also Bioremediation Calvin cycle Citric acid cycle Electrochemistry Galvanic cell External link Redox...
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