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Selectively in Medical News

Researchers Identify New Method to Selectively Kill Metastatic Melanoma Cells

An international team of researchers has identified a new method for selectively killing metastatic melanoma cells, which may lead to new areas for drug development in melanoma - a cancer that is highly resistant to current treatment strategies. Richmond, Va. (Vocus) Au...

Researchers identify new method to selectively kill metastatic melanoma cells

RICHMOND, Va. (August 3, 2009) An international team of researchers has identified a new method for selectively killing metastatic melanoma cells, which may lead to new areas for drug development in melanoma a cancer that is highly resistant to current treatment strategies. Researchers from V...

Study finds that sleep selectively preserves emotional memories

BOSTON As poets, songwriters and authors have described, our memories range from misty water-colored recollections to vividly detailed images of the times of our lives. Now, a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) and Boston College offers new insights into ...

Tumor-killing virus selectively targets diseased brain cells

WASHINGTON, DC February 19, 2008 New findings show that a specialized virus with the ability to reproduce its tumor-killing genes can selectively target tumors in the brains of mice and eliminate them. Healthy brain tissue remained virtually untouched, according to a Feb. 20 report in The Journa...

CSHL scientists make progress in determining how the brain selectively interprets sound

Cold Spring Harbor, NY Scientists at Cold Spring Harbor Laboratory (CSHL) have reported new findings about how the mammalian brain interprets and fashions representations of sound that may help explain how we are able to focus on one particular sound among many in noisy environments such as offic...

U.S. Navy Awards Entegrion Contracts for $4 Million for the Development of Critical Blood Products

...kets that will follow," said Stan Eskridge, Chief Executive Officer of Entegrion. About Entegrion: Entegrion is a life sciences company that selectively integrates synergistic technologies with those in its patent portfolio for development of novel devices and drugs for hemorrhage control, resuscitatio...
Selectively in Medical Technology

FDA Issues Complete Response Letter for INTUNIV(TM) (guanfacine) Extended Release for the Treatment of ADHD in Children and Adolescents

...stance and has no known potential for abuse or dependence. Guanfacine, the active ingredient in INTUNIV, is thought to work directly by binding selectively to alpha-2A adrenergic receptors located in the prefrontal cortex - an area of the brain that has been linked to ADHD.(4-6) Stimulation of the postsyn...

Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech

...lection markers, thereby enabling the rapid generation of cell lines in which multiple genes have been knocked out. Our proven ability to quickly and selectively knock out multiple genes in the same cell line creates endless possibilities for biopharmaceutical companies to improve their manufacturing capability...

Data Demonstrates Long-Term Reduction In Seizure Frequency With Novel Once Daily Anti-Epileptic Zebinix(R)

...file. About Eslicarbazepine Acetate Eslicarbazepine acetate (ESL) is a novel once-daily voltage-gated sodium channel blocker designed to selectively inhibit the rapid firing of nerve cells that causes seizures. It specifically targets the inactivated state of the ion channel, preventing its return ...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

...ailure and increased risk of heart attack and stroke. Amigal is designed to selectively bind to and stabilize a-Gal A, which facilitates proper trafficking of the ...armacological chaperone technology involves the use of small molecules that selectively bind to and stabilize proteins in cells, leading to improved protein foldin...

Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome

... autoimmune diseases. However, a specific form of the proteasome, known as the immunoproteasome, is found in many cells of the immune system. PR-957 selectively targets a subunit of the immunoproteasome, known as LMP7. Inhibition of this subunit results in a decrease of the immune cell signaling cascade and a...

PROTECT-1 Phase II/III Induction-Stage Results for ChemoCentryx's Traficet-EN(TM) Presented in Oral Session at DDW 2009 Conference

...orally-active inhibitor of the chemokine receptor known as 'CCR9', which is selectively expressed by inflammatory T cells to migrate to the digestive tract in a pr...dults, CCR9 is a highly specific receptor expressed by T cells that migrate selectively to the digestive tract. The trafficking of T cells to the small and large ...
Selectively in Medical Products

Sorting System RS 800

Description:...cal way even after being given sorting priorities. Optionally a Tube Type Identification via Cap Recognition or a Decapping Module can be integrated. selectively decapping is possible. The Sorting System RS 800 has a throughput capacity of up to 800 tubes per hour....
Company:PVT LabSystems LLC

Decapping System DS 800

Description:... The Decapping System DS 800 selectively removes closures from various sample tubes with different caps and aligns the barcode towards the rack opening in one run. The Decapping Module DS 800...
Company:PVT LabSystems LLC

ICON 20 hCG

Description:...G from Beckman Coulter. ICON 20 hCG is a rapid test for detecting hCG qualitatively, employing a solid-phase chromatographic immunoassay technology to selectively detect elevated levels of hCG in serum or urine....
Company:Beckman Coulter, Inc

OLA2500™ High Speed Sorter

Description:... OLA2500 High Speed Sorter (HSS) system, dedicated for pre- and post-analytical sorting requirements. As a front-end sample-processor, the OLA2500 HSS selectively decaps and then sorts primary sample tubes to their destination racks quickly to save time, labor, and eliminate sample-handling errors. Post-analyti...
Company:Olympus America Diagnostics

Salmonella Typhi Antigen - Rapid Test

Description:...y. The test employs a conation of monoclonal antibody/colloidal gold dye conjugate and a polyclonal antibody immobilized on the solid phase. This will selectively identify S. typhi antigen associated Salmonella typhi (typhoid) infection with a high degree of sensitivity and specificity....
Company:Bio-Quant, Inc.

AmkaiCharts

Description:.... It is a proven, comprehensive electronic medical record designed to be used by ambulatory healthcare providers at the point of care and to be shared selectively via an intranet and/or through the Internet. AmkaiCharts chronicles patient history, encounters, medication orders, procedures, referrals and vital st...
Company:Amkai, Inc.
Selectively in Medical Dictionary

Membrane

...receptors can be altered by changing the physical ... Changes in membrane fluidity not only reduce the affinity of binding of the ... ... sounds selectively vibrate the basilar membrane of the inner ear near the ... is based on the location along the membrane where the hair cells are stimulated. ... ...
Selectively in Biological News

MIT student develops new innovations to selectively kill cancer cells

CAMBRIDGE, Mass. (March 3, 2009) When it comes to solving complex problems, Geoffrey von Maltzahn, MIT graduate student and biomedical engineer, looks to nature for solutions. Finding inspiration in systems that evolution has produced, von Maltzahn is currently helping to tackle one of society's ...

Cells selectively absorb short nanotubes

DNA-wrapped single-walled carbon nanotubes (SWCNTs) shorter than about 200 nanometers readily enter into human lung cells and so may pose an increased risk to health, according to scientists at the National Institute of Standards and Technology (NIST). The results of their laboratory studies appear...

Tamoxifen-like drug suggests new ways to selectively block estrogen

The ability of an experimental drug known as GW5638 to change the shape of the estrogen receptor is helping researchers understand why drugs like tamoxifen and raloxifene behave the way they do, simulating the effects of estrogen in some tissues and blocking it in others. The finding indicates that...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... PHILADELPHIA Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 1...

International research team seeks to unravel flatworm regeneration

...ure generations, and particulary to protect it against the uncontrolled propagation of mobile genetic elements, transposons. PiRNAs have been shown to selectively silence transposons in the fly and mouse genomes. Due to their analysis the researchers assume that piRNAs have a similar function in the planarian st...

Early-life experience linked to chronic diseases later in life: UBC research

...of Sciences , shows that among subjects with low early-life socioeconomic circumstances, there was evidence that genes involved with inflammation were selectively "switched-on" at some point. Researchers believe this is because the cells of low-SES individuals were not effectively responding to a hormone called ...
Selectively in Biological Technology

MicroFluidic Systems (MFSI) Receives Patent for Method to Selectively Process Different Biological Cell Types for Analysis.

FREMONT, Calif., June 16 /PRNewswire/ -- Microfluidic Systems, a privately-held company, announced today that they received patent number 7,541,166, entitled "Sonication to Selectively Lyse Different Cell Types". This method, originally applied to the process of differential extraction of male/fem...

CeNeRx BioPharma Awarded New Patent for its Innovative Compounds That Selectively Target Peripheral Cannabinoid Receptors

--By Avoiding the CNS, These Compounds May Be Free of the Side Effects Associated with Traditional Cannabinoid Compounds-- RESEARCH TRIANGLE PARK, N.C., April 1 /PRNewswire/ -- CeNeRx BioPharma, Inc., a clinical stage company developing and commercializing innovative treatments for diseases o...

Data Published in Cell Stem Cell Demonstrates Potent Anti-Cancer Activity for OncoMed Pharmaceuticals' Lead Antibody

... About OMP-21M18 OMP-21M18 is a monoclonal antibody optimized to block a key signaling pathway in cancer stem cells. Specifically, OMP-21M18 selectively targets Delta-like ligand 4 (DLL4), an activator of Notch signaling, which is a pathway known to be important in stem cells and cancer. Blocking DLL4...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results

...gical chaperones for the treatment of a range of human genetic diseases. Pharmacological chaperone technology involves the use of small molecules that selectively bind to and stabilize proteins in cells, leading to improved protein folding and trafficking, and increased activity. Amicus is initially targeting ly...

Rapid heating prepares energy-saving zeolite for greater role in industrial separations

...ores, being small and very uniform in size, can sort and separate molecules selectively according to the molecules' size. As microscopic particles, zeolites are...g the first teams to use the technique to characterize zeolite membranes by selectively labeling grain boundary defects with fluorescing molecules. The zeolite the...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results Release Date

...gical chaperones for the treatment of a range of human genetic diseases. Pharmacological chaperone technology involves the use of small molecules that selectively bind to and stabilize proteins in cells, leading to improved protein folding and trafficking, and increased activity. Amicus is initially targeting ly...
Selectively in Biological Products

Vybrant Apoptosis Assay Kit #4 from Molecular Probes (Invitrogen)

Description:...the permeability of cell membranes. This kit contains ready-to-use solutions of both YO-PRO-1 and propidium iodide nucleic acid stains. YO-PRO-1 stain selectively passes through the plasma membranes of apoptotic cells and labels them with moderate green fluorescence. Necrotic cells are stained red-fluorescent wi...
Company:Molecular Probes (Invitrogen)

Affi-Prep Protein A Support, 25 ml from Bio-Rad

Description:... For affinity chromatography, Affi-Prep protein A media yield highly purified immunoglobulins (IgG), selectively remove IgG prior to analysis of other immunoglobulin classes, or adsorb immune complexes for antigen purification. Protein A binds to the Fc region of...
Company:Bio-Rad

Glycoprotein Isolation Kit WGA from Pierce Biotechnology, Inc.

Description:...nd cultured cell lysates thus enabling downstream analysis. ConA lectin, recognizes a-linked mannose and terminal glucose residues while WGA lectin, selectively binds to N-Acetyl glucosamine (GlcNAc) groups and to sialic acid. High recovery Equivalent or greater glycoprotein recovery versus competitor ki...
Company:Pierce Biotechnology, Inc.

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils....
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils....
Company:Cayman Chemical

5-OxoETE-d7, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...keto acid formed by the oxidation of 5-HETE in human neutrophils. It stimulates cytosolic calcium levels in neutrophils with an EC50 of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the mitogen-activated protein kinase (MAPK) pathway in stimulated neutrophils....
Company:Cayman Chemical
Selectively in Biological Definition

Antibiotic

...amycin Fusidic acid Trimethoprim Another such classification is by their mechanism of action (that is, the mechanism by which they selectively poison bacterial cells): Antibiotics which interfere with cell-wall synthesis Beta-lactams, including penicillins and cephalosporins; mono-...

Apoptosis

... be dramatically restored in H460 cells with a Smac peptide (SmacN7) that targets IAPs. Yang and her team successfully developed a SmacN7 peptide that selectively reversed apoptosis resistance - and hence tumor growth - in H460 cells in mice. (See also the role of Gefitinib and peptidomimetics in restoring...

Biodiversity

...here are real ecological effects of biodiversity . Unusual and wild strains of maize are collected to increase the crop diversity when selectively breeding domestic corn. Economic role of biodiversity For all humans, biodiversity is first a resource for daily life. Such 'crop diversit...

Biological membrane

... from its surrounding medium. Most organelles are defined by such membranes. Probably the most important feature of a biomembrane is that it is a selectively permeable structure. This means that the size, charge and other chemical properties of the atoms and molecules attempting to cross it will deter...

Diabetes mellitus

...rtion of type 1 cases has the hereditary condition maturity onset diabetes of the young (MODY). Some poisons (e.g. certain rat poisons ) work by selectively destroying certain types of cells, including pancreatic beta cells, thus producing "artificial" type 1 diabetes. Other pancreatic problems including t...

Diffusion

...f transport is governed by the viscosity of the fluid and the momentum gradient. Osmosis Osmosis is the diffusion of a solute across a selectively permeable membrane . Photon diffusion When photons travel through a material with a high optical depth and a very short mean free path ,...
Selectively in Biological Dictionary

Small nuclear RNA

... small nuclear RNAs (snRNAs) are involved in RNA splicing (see below), and other small RNAs... The U1 small nuclear RNA -protein complex selectively binds a 5' splice site in vitro. ... site of U1 small nuclear RNA processing and ribonucleoprotein ... U2 small nuclear RNA precu...

Polymorphic loci

...s the premier Web site for the pharmaceutical ... Optionally, a set of nucleotides occupying a set of the polymorphic loci shown in FIGS. ... selectively Amplified Microsatellite Polymorphic Loci . Start using this tool. Selective amplified microsatellite polymorphic loci (SAMPL) analysis (Wits...

Pollen tube

...y a pollen grain which penetrates and ... The precise guidance of the pollen tube to the embryo sac is critical to the ... Pollen tubes selectively arrived at complete, unfertilized embryo sacs but did ... germinates and forms the pollen tube , which grows through the stigma, style, ... P...

Isozymes

...on of phospholemman ... The present invention provides fluorescence-based methods for sensitively detecting total ADH activity in human sera and selectively measuring the activity of ... Protein kinase C (PKC) isozymes regulate epithelial barrier function and alter ... In various model systems, PKC ...

Intergenic DNA

...Dot Plots ... Chimpanzee hemoglobin intergenic DNA against spider monkey. ... Further more, this is intergenic DNA with no known function to selectively ... ...

Gene knockout

...ave been sequenced,... STUDYING GENE FUNCTION: CREATING KNOCKOUT MICE. By Hubert Walinski (August 2004) ... The gene knockout is created by selectively disabling a specific target gene in ... C. elegans Consortium Home Page ... C. elegans Gene Knockout Consortium is to ... © Copyright 2001-20...
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Breaking Medicine News(10 mins):Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 3Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 4Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3
(Date:12/19/2014)... 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ... its team and bring LaunchKey to market in 2015. ...
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Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
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