Gene therapy eliminates brain tumors through selective recruitment of immune cells
LOS ANGELES (January 13, 2009) Scientists seeking to harness the power of the immune system to eradicate brain tumors face two major hurdles: recruiting key immune cells called dendritic cells into areas of the brain where they are not naturally found and helping them recognize tumor cells as tar...
UltraShape(R) Commences Pivotal Study for First Non-Invasive Fat Reduction and Body Contouring Device Using Non-Thermal Selective Focused Ultrasound
YOQNEAM, Israel and SAN RAMON, California, June 12 /PRNewswire/ --
- Study Will Evaluate Safety and Effectiveness of Contour Plus(TM)
UltraShape(R), a global leader in non-invasive fat reduction and body
contouring, today announced the commencement of its pivotal IDE
Moving beyond tamoxifen: Drug discovery and the future of selective hormone receptor modulators
How did a failed contraceptive become the first targeted therapy for the treatment of breast cancer" The transformation of tamoxifen, from cast-off to lifesaver, laid the foundation for a new class of therapeutics selective
estrogen receptor modulators that could treat or prevent a variety of hu...
Pharmacopeia Acquires Selective Androgen Receptor Modulator ('SARM') Program from Bristol-Myers Squibb
PRINCETON, N.J., Oct. 15 /PRNewswire-FirstCall/ -- Pharmacopeia
(Nasdaq: PCOP ), an innovator in the discovery and development of novel
small molecule therapeutics, today announced that it has licensed from
Bristol-Myers Squibb (NYSE: BMY ) a selective
androgen receptor modulator
Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
A nanoparticle drug delivery system designed for brain tumour therapy has shown promising tumour cell selectivity in a novel cell culture model devised by scientists at The University of Nottingham. The project, conducted jointly by the Schools of Pharmacy, Biomedical Sciences and Human Developmen...
Lung Cancer Alliance Calls American Cancer Society's Claim of Progress Selective
WASHINGTON, May 29 /PRNewswire-USNewswire/ -- Lung Cancer Alliance (LCA) said that the American Cancer Society's claim of "progress in cancer fight" earlier this week was based on "selective culling of statistics and ignores the dismal truth that we have made very little progress on the most letha...
Selective in Medical Technology
Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity
EMERYVILLE, Calif., July 17 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One.
Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome
Findings Published in Nature Medicine Suggest Broad Implications for the Treatment of Inflammatory and Autoimmune Disorders
SOUTH SAN FRANCISCO, Calif., June 15 /PRNewswire/ -- Proteolix, Inc. announced that in an article published today in Nature Medicine, Proteolix's selective
BRIDION(R) (sugammadex) Injection - First and Only Selective Relaxant Binding Agent - Approved in European Union
BRIDION allows anesthesiologists to rapidly reverse both moderate and deep levels of muscle relaxation
First product approval from the Schering-Plough combination with Organon BioSciences
KENILWORTH, N.J., July 29 /PRNewswire-FirstCall/ -- Sch...
Pharmacyclics Reports Multiple Presentations at AACR on Its HDAC and Selective HDAC Inhibitors
SAN DIEGO and SUNNYVALE, Calif., April 15 /PRNewswire-FirstCall/ --
Pharmacyclics, Inc. (Nasdaq: PCYC ) today announced preclinical data from
four presentations at the Annual Meeting of the American Association for
Cancer Research (AACR) being held this week in San Diego, CA. Results from
FDA Advisory Committee Unanimously Recommends U.S. Approval of Sugammadex, the First and Only Selective Relaxant Binding Agent
Committee Recommends FDA Approve Novel Anesthesia Drug to Reverse Muscle relaxation within Minutes
KENILWORTH, N.J., March 11 /PRNewswire-FirstCall/ -- Schering-Plough
(NYSE: SGP ) today announced that the U.S. Food and Drug Administration
(FDA) Advisory Committee on Ane...
Exelixis Presents Encouraging Phase 1 Data For XL019, A Novel Selective Inhibitor of JAK2
ATLANTA, Dec. 10 /PRNewswire-FirstCall/ -- Exelixis, Inc. (Nasdaq:
EXEL), today reported phase 1 data from an ongoing phase 1 trial of XL019
in patients with myelofibrosis, a myeloproliferative disorder (MPD). XL019
is an investigational small molecule that selectively inhibits the tyrosine
Selective in Medical Products
VASER Ultrasound Lipoplasty System
Description:...epresents a major advance in the application of ultrasonic technology to cosmetic procedures. Combined with precision fluid management, controlled and selective
tissue emulsification, a solid grooved probe design and patented cannulae, only the VASER System has been designed to minimize trauma to the tissue ma...
Company:Sound Surgical Technologies LLC
STA DEFICIENT VII
Description:... Substrate Plasma for Factor VII Assay by STA© Analyzers. Freeze-dried human plasma from which factor VII has been removed by selective
Company:Diagnostica Stago, Inc.
STA DEFICIENT X
Description:... Substrate Plasma for Factor X Assay by STA© Analyzers. Freeze-dried human plasma from which factor X has been removed by selective
Company:Diagnostica Stago, Inc.
STA DEFICIENT VIII
Description:... Substrate Plasma for Factor VIII Assay by STA© Analyzers. Freeze-dried human plasma from which factor VIII has been removed by selective
Company:Diagnostica Stago, Inc.
STA DEFICIENT IX
Description:... Substrate Plasma for Factor IX Assay by STA© Analyzers. Freeze-dried human plasma from which factor IX has been removed by selective
Company:Diagnostica Stago, Inc.
Total PSA IRMA Test
Description:...ypertrophy (BPH) and prostatitis [1-3]. In addition, PSA serum levels appear to correlate with the volume and clinical stage of prostate cancer [1,4]. selective
determination of the various forms of PSA (i.e. free PSA, PSA-ACT complex and total PSA) may be useful to distinguish BPH from untreated prostate canc...
Company:Diagnostic Systems Laboratories, Inc.
Selective in Medical Definition
Medical Scientist Training Program
... Medical Scientist Training Programs are highly selective
combined M.D. and Ph.D. graduate degree programs offered by a number of U.S. medical schools with grant support from the National Institute...
...opathies pl .; proteopathic adj .). Proteopathy is the abnormal accumulation and toxicity of proteins in certain disease states.  Also, selective
hyperproteolytic diseases have been referred to this category, e.g. critical illness myopathies or tumor cachexia.  The proteopathies comprise a...
...a prerequisite for thymopoiesis. Immunol Rev 209:47, 2006. full text
^ Schwarz BA, Sambandam A, Maillard I, Harman BC, Love PE, Bhandoola A. selective
thymus settling regulated by cytokine and chemokine receptors. J Immunol. 2007 Feb 15;178(4):2008-17. http://www.jimmunol.org/cgi/content/full/178/4/...
Selective in Medical Dictionary
...itamin B12 is a member of the vitamin B complex. ... There has been considerable research into proposed plant sources of vitamin B12 . ... selective
impaired absorption of vitamin B12 due to intrinsic factor deficiency. ... Vitamin B12 enhances the phase-response of circadian melaton...
...K-tant). Surfactant is a liquid that coats the ... BACKGROUND: Both prophylactic and early surfactant replacement therapy, compared with later selective
surfactant administration, reduce mortality and pulmonary ... Abstract and Introduction: A systematic review and meta-analysis of exogenous s...
..... Main article: Nerve plexus ... Retrieved from "http://en.wikipedia.org /wiki/ Plexus " ... An online gallery, a journal, and a selective
archive of art, video, criticism, theory, poetry and literature. ArtLab: an environment of digital, audio, video, and web-specific media. ... the ...
... A membrane is a layer of material which serves as a selective
barrier between two phases and remains impermeable to specific particles, m... dedicated ... of the proteins in the membrane function to help carry out selective
... The membrane is not a barrier with the molecule being soluable in ......
...anisms. The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective
breeding. However,... We know that species ranging from microbes to humans have similar genes and genetic pathways. ... By studying the genes...
... up in damp areas such as public gyms, shower stalls ... For instance, one fungus growing on wallpaper released the highly toxic gas ... be of selective
advantage to the survival of the fungus , if not to the consumer. ... Prescription Drugs For Treating Fungus , Yeast, And Candida Infections. Se...
Selective in Biological News
Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. The project, conducted jointly in the Schools of Pharmacy, Biomedical Sciences and Human Development, will b...
Erectile dysfunction in diabetes is due to selective defect in the brain
A new study sheds additional light on how erectile dysfunction (ED) interacts with diabetes. The study is another step in uncovering the link between the two disorders, and may lead to improved efficacy in treatments.
The study, "Lack of Central Nitric Oxide Triggers Erectile Dysfunction in Diab...
Motorola researchers develop selective sensors based on carbon nanotubes
A team of researchers from Arizona State University and Motorola Labs, the applied research arm of Motorola Inc., has developed sensors based on carbon nanotubes, microscopically small structures that posses excellent electronic properties. In early tests, the new devices detected the presence of h...
Carnegie donates landmark clones to biology
... mutation can make the transporters work independently. So why did this simpler mutation not succeed? The researchers believe that there must still be selective
pressure on the system. The simplest explanation is that the mechanism is still necessary today, probably to control uptake and prevent toxicity.
New hope for fisheries
...ound that a combination of approaches, such as catch quotas and community management coupled with strategically placed fishing closures, ocean zoning, selective
fishing gear and economic incentives, offer promise for restoring fisheries and ecosystems. However "lessons from one spot need to be applied very car...
Global curbs on overfishing are beginning to work
...fishery scientists, managers and industry. Management measures included catch quotas coupled with strategically placed fishing closures, ocean zoning, selective
fishing gear, community co-management and economic incentives (such as individual transferable quotas).
"Exploitation rates have more than halved s...
Selective in Biological Technology
Supelco(R) and MIP Technologies Launch New SPE Product for the Selective Extraction of NSAIDs From Environmental Water
ST. LOUIS, July 16 /PRNewswire-FirstCall/ -- Supelco, a division of Sigma-Aldrich (Nasdaq: SIAL ), and MIP Technologies AB announced today the launch of a new molecularly imprinted polymer, SPE product, SupelMIP(TM), for the selective
extraction of non-steroidal anti-inflammatory ...
Pharmos Announces Agreement to Sell Certain CB2 Selective Agonists
ISELIN, N.J., Feb. 18 /PRNewswire-FirstCall/ -- Pharmos Corporation (Nasdaq: PARS ) announced today that it has entered into an agreement with an Israel based company, Reperio Pharmaceuticals Ltd. (Reperio) for the sale of the patent rights and technical know how related to the compound known as...
Bionovo Publishes Discoveries in Predictable Tissue Selectivity for Selective Estrogen Receptor Modulators Platform
EMERYVILLE, Calif., Jan. 2 /PRNewswire-FirstCall/ -- Bionovo, Inc.
(Nasdaq: BNVI ) announced today results describing predictable estrogen
regulatory elements that can be used to identify estrogenic drugs that are
safer. The data, published in Molecular and Cellular Endocrinology, showed
Dana-Farber Cancer Institute Commences Phase 1 Trial With EntreMed's Selective Kinase Inhibitor
Dana-Farber and Colorado Treating Patients with ENMD-2076
ROCKVILLE, Md., May 8 /PRNewswire-FirstCall/ -- EntreMed, Inc. (Nasdaq:
ENMD), a clinical-stage pharmaceutical company developing therapeutics for
the treatment of cancer and inflammatory diseases, today announced that
Bionovo Identifies and Describes ER-beta Selective Compounds for the Treatment of Vaginal Dryness
Dr. Scott Baggett to Present Results at American Society of Pharmacognosy
EMERYVILLE, Calif., April 14 /PRNewswire-FirstCall/ -- Bionovo, Inc.
(Nasdaq: BNVI ) will present seminal information on a new drug candidate for
the treatment of vaginal dryness at the 7th Annual Oxford International
ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA
...Ebinuma of the Tsukuba Research Institute in the journal Clinica Chimica Acta in February 2009.
Recently, an ELISA system was developed for the selective
quantification of human adiponectin oligomers using protease pretreatment, and the Mouse HMW Adiponectin ELISA kit reflects a similar system for simul...
Selective in Biological Products
GIBCO Geneticin Selective Antibiotic liquid from Invitrogen
Description: Geneticin Selective
Rabbit Protein Phosphatase 1 (PP1) from Upstate
Description:... PP1, purified Formulation: 0.15M NaCl, 20mM MOPS, pH 7.5, 60mM 2-mercaptoethanol, 0.1mM MnCl2, 1mM MgCl2, 1mM EGTA, 10 Properites: For selective
in vitro dephosphorylation of proteins Purification: DEAE chromatography, divalent cation activation plus trypsin digestion, and gel filtration chroma...
One•STrEP™ Protein Interaction Kit from Novagen
Description:...ct protein complexes. Unlike other systems that require tedious optimization or multiple purification steps, this system takes advantage of the highly selective
StrepTactin Superflow Column for fast protein purification under physiological conditions with low background. With the OneSTrEP Protein Interaction K...
Anisomycin from Sigma-Aldrich
Description:...eukemia cells, Jurkat cells, ventricular myocytes, and colon adenocarcinoma cells. Initiates intracellular signals and immediate early gene induction. selective
signaling agonist. Potent Jun-NH2terminal kinase (JNK) agonist. Activates mitogen-activated protein (MAP) kinases (JNK/SAPK and p38/RK). Antiprotozoal...
SureLINK Bioconjugation Kit from KPL
Description:...red in the SureLINK Bioconjugation Kit is superior to conventional methods of bioconjugation such as maleimide/thiol and avidin/biotin. Using a highly selective
interaction of hydrazine and carbonyl groups, the coupling reaction results in a hydrazone bond that is extremely stable. Additionally, no reducing r...
S1 Nuclease from Promega
Description:...dation except with extremely high concentrations of enzyme (1). The enzyme is used to remove single-stranded termini from double-stranded DNA (2), for selective
cleavage of single-stranded DNA and for mapping RNA transcripts (3)....
Selective in Biological Definition
...nd third generation cephalosporins , greatly hastens the development of methicillin resistance, even in organisms that have never been exposed to the selective
pressure of methicillin per se . Other factors contributing towards resistance include incorrect diagnosis, unnecessary prescriptions, improper use o...
...bryos - specifically on chick neural tube development - has suggested how selective
cell proliferation, combined with selective
apoptosis, sculpts developing tissues in vertebrates. During vertebrate emb...
...at the size, charge and other chemical properties of the atoms and molecules attempting to cross it will determine whether they succeed to do so. selective
permeability is essential for effective separation of a cell or organelle from its surroundings.
If a particle is too large or otherwise unable to c...
8000BC Collecting of seeds for replanting. Evidence that Babylonians , Egyptians and Romans used selective
breeding ( artificial selection ) practices to improve livestock .
6000BC Brewing beer , fermenting wine , baking bread with help of yeast...
... or vitamin E or both experience a reduced incidence of prostate cancer in comparison to men taking placebo pills.
Daily use of tamoxifen , a selective
estrogen receptor modulator, for up to 5 years, has been demonstrated to reduce the risk of developing breast cancer in high-risk women by about 5...
...licated process of meiosis? You may think you know why you have sex , but you probably do not know the real reason; the reason why meiosis confers a selective
advantage . Notice that when meiosis starts, the two copies of chromosome number 2 are adjacent to each other. During this time, there can be genetic...
Selective in Biological Dictionary
... Mouse protein-coding gene Ubc. Represented by 2568 ESTs from 329 cDNA libraries. ... Ubiquitin , becomes conjugated to proteins, marking them for selective
... Ubiquitons and Zomes ( Ubiquitin and Proteasome) ... Ubiquitin -like Proteins and Derivatives. Ubiquitin and Ubiquitin -like Protein Casca...
...g of TATA box as a finance term. What does TATA box mean in finance? ... TATA box . Tax and loan account. tax anticipation bill. Tax ... selective
Binding of the TATA Box -Binding Protein to the TAT... Binding Mechanisms of TATA Box -Binding Proteins: DNA Kinking is Stabilized by ... The...
Ribosome binding site
...iology dictionary,biology terminology,biology terms,biology abbreviations ... promoter and ribosome binding site codes in ... ... shows the selective
binding site on the mRNA which is attached in the ribosome . ... After binding to the A site , the peptide bond between the methionine ... ...
...mmediate response capacity, will assist ... In most instances, the response elements will remain under State control. ... Direct repeats as selective
response elements for the thyroid hormone, retinoic ... nucleotide, and the resulting retinoic acid response element is no longer a TRE. ... ...
...e in ... News archive for repetitive DNA . Anti-aging compound claims to reset the clock - 21 Aug 2007 ... Repetitive DNA , with different selective
pressures from those acting on genes ... The repetitive DNA in the genome is also important for evolutionary, genetic, ... Repetitive , DNA ...
...ices on the Latest Styles and Save Big! The progesterone receptor is an intracellular steroid receptor that specifically ... ( receptor ) ... selective
estrogen receptor modulator: Bazedoxifene, ... Information about receptor in the free online English dictionary and ... receptor ... entero...