Gene variations explain drug dose required to control seizures
Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose of ant...Molecular mechanism may explain how fevers spark seizures
It's one of those unavoidable facts of life -- kids get sick and have fevers. Usually, those elevated internal temperatures cause only temporary discomfort, but in some small children they spark convulsions called "febrile seizures." These convulsions are "scary and very upsetting to parents," said Robert L. Macdonald, M.D., Ph.D., professor and chair of Neurology. They've also been somet...Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent
The brain's septum helps prevent epileptic seizures by inducing rhythmical electrical activity in the circuits of another area of the brain known as the hippocampus, according to a new study in the Journal of Neurophysiology. The researchers found that, by imposing a normal "theta" rhythm on chronically epileptic rats, they could reduce epileptic seizures by 86-97 percent. The study "Septo...How brain injury leads to seizures, memory problems
In a finding that may provide a scientific basis for eventual treatment, neurology researchers have shown that traumatic brain injury reduces the level of a protein that helps keep brain activity in balance. The resulting abnormal activity, in turn, is thought to be an underlying reason for seizures and memory defects experienced by people who have suffered a traumatic brain injury (TBI)....Epileptic Seizures Can Be Duec to Heart Problem
British researchers have said that Many people thought to have epilepsy may have a heart problem instead. In a study, researchers closely examined people diagnosed with epilepsy who did not respond well to medication or had symptoms unusual for the disorder. They found that more than 40% had another medical problem--most often a heart or circulation condition--that could have caused the symptoms....Antiparasitic Drug Effective In Reducing Seizures In Neurocysticercosis Patients
Neurocysticercosis is an infection of the central nervous system caused by the Taenia solium larvae. The condition is considered the most common type of acquired epilepsy around the world. In Latin America//, for example, the disease affects about 400,000 people. New research shows an antiparasitic drug appears to help people avoid seizures caused by a common parasite. Researchers...Seizures in Children , Sensed By Dogs
A new study shows dogs may be able to anticipate seizures in children with epilepsy.The most common response behavior from the dogs in this study was // licking, often of the face, followed by decreased motor activity, whimpering, and “protective" behavior without aggression. In previous studies, owners of seizure-sensitive dogs reported that licking may abort or even prevent their seizures. So...Albendazole Effective In Reducing Seizures Caused By A Common Parasite
New research shows an antiparasitic drug appears to help people avoid seizures caused by a common parasite Taenia solium.// Researchers speculated treatment with the antiparasitic drug albendazole which they thought might help these patients reduce the number of seizures they experience. They randomized 120 patients with signs of the living parasite in their brains to receive either 800...Intractable Seizures Can Be Handled By A Three-Stage Brain Operation, Neurosurgeon
A neurosurgeon has reported his promising results about a three-stage brain surgery, performed on 25 children with tuberous sclerosis//, a genetic disorder characterised by intractable seizures. Sadly, none of the treatments for epilepsy—anti-seizure medications, a procedure called vagus nerve stimulation, a special diet —could quell the electrical storms in the young boy’s brain. Cau...New Data Shows Once a Day Lamictal XR is Effective in Treating Patients with Partial Seizures
Data Presented at the American Academy of Neurology Annual MeetingShow Approximately 50 Percent Reduction in Partial Seizures BOSTON, May 01, 2007 /PRNewswire/ -- Data from two clinicaltrials presented today at the American Academy of Neurology (AAN)meeting suggest that an investigational once daily extended releaseformulation of Lamictal(R) (lamotrigine) is effective as add-ontreatment i...