Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
Gene therapy methods that specifically target muscle may reverse the symptoms of a rare form of muscular dystrophy, according to new research in mice conducted by medical geneticists at Duke University Medical Center. Infants born with the inherited muscular disorder called Pompe disease usually die before they reach the age of two. The researchers also said their approach of targeting corrective...X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power
What is the connection between a fly’s aerodynamic skill and human heart function? Using the nation’s most brilliant X-rays, located at the Advanced Photon Source at the U.S. Department of Energy’s Argonne National Laboratory, a cardiac molecular motors expert from the University of Vermont (UVM) and colleagues from the Illinois Institute of Technology (IIT) and Caltech performed research to answ...Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients
Multiple sclerosis (MS) can be an unpredictable disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independently or in combination, sporadically or persistently. Although symptoms appear in no particular orde...Young Blood Revives Aging Muscles, Stanford Researchers Find
Any older person can attest that aging muscles don't heal like young ones. But it turns out that's not the muscle's fault. A study in the Feb. 17 issue of Nature shows that it's old blood that keeps the muscles down. The study, led by Thomas Rando, MD, PhD, associate professor of neurology and neurological sciences at the Stanford University School of Medicine, built on previous work show...Interspecies Trial Array 2: N Brain, N Liver, N Muscle, N Kidney from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...Human Skeletal Muscle RACE-Ready cDNA from Ambion
Description:...C2C12 cell line slides ( mouse: muscle; myoblast ) from GeneTex
Description:Mouse C2C12 cells were cultured in DMEM and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background staining. Each well is loaded with approximately 7. 5 x...RayBio Mouse Atherosclerosis Antibody Array I & 1.1 Service from Raybiotech, Inc.
Description:Request Info...Primary cells, rat heart muscle
Primary cells: Adult heart muscle cells from rat, 6...Laser Capture Microdissection of muscle fiber populations and expression analysis by RT-PCR
To locate gene products in distinct muscle fiber populations of different muscle allotypes, a novel protocol was established. A rapid method to distinguish muscle fiber types using histochemistry and...Early Stage, Step 8: Misclassifying workers brings risk
- Wisconsin's unemployment insura...Healthcare software addresses "90 million" misclassified Americans
Then imagine employers basing their health plan buying decisions on the often inaccurate information contained in that tool. Employers don't have to imagine such a scenario because they have been living it, unbeknown to them, for yea...Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
A novel modification of a new technology born of genetic engineering, and known as naked DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The vaccine is currently being successfully tested in animals. In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, caus...Half of world's children are passive smokers - damning disclosure from WHO
The world health organisation has come out with a damning disclosure that half the world's children are passive smoke. In a message on "No Tobacco Day 2001," World Health Organization chief Gro Harlem Brundtland said 700 million children were exposed to the health hazard because most governments still allowed smoking in public places. She added that scientists around the world agreed that...The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned
A recent study by Harvard researchers suggests a link between the hepatitis B vaccination and multiple sclerosis. In their study, people who received the vaccine were three-times more likely to develop MS // over the next three years than those who were not vaccinated. While this finding is disturbing, the investigators emphasize the overall effect of the vaccine on the development of MS...Accelreon Pharma's ACE-031Shown to Increase Muscle Mass in Preclinical Studies
LUCCA, ITALY, May 14, 2007-Acceleron Pharma, Inc., abiopharmaceutical company developing therapeutics for the treatmentof musculoskeletal, metabolic and cancer-related diseases, todayannounced results of a preclinical study with ACE-031 thatdemonstrated the ability of the compound to increase muscle massand strength in normal mice and in murine models of musculardystrophy. ACE-031...