Scl

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

Gene therapy methods that specifically target muscle may reverse the symptoms of a rare form of muscular dystrophy, according to new research in mice conducted by medical geneticists at Duke University Medical Center. Infants born with the inherited muscular disorder called Pompe disease usually die before they reach the age of two. The researchers also said their approach of targeting corrective...

X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power

What is the connection between a fly’s aerodynamic skill and human heart function? Using the nation’s most brilliant X-rays, located at the Advanced Photon Source at the U.S. Department of Energy’s Argonne National Laboratory, a cardiac molecular motors expert from the University of Vermont (UVM) and colleagues from the Illinois Institute of Technology (IIT) and Caltech performed research to answ...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

Multiple sclerosis (MS) can be an unpredictable disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independently or in combination, sporadically or persistently. Although symptoms appear in no particular orde...

Heart repair gets new muscle

Some organs in the human body deal with injury better than others. A flesh wound or muscle tear might hurt, but, assuming you are otherwise healthy, both will heal. The prognosis for a heart attack, on the other hand, is not so clear-cut. It has long been thought that cardiac cells (cardiomyocytes) lack the capacity for self-renewal and repair, impeding the chances of a full recovery from...

Young Blood Revives Aging Muscles, Stanford Researchers Find

Any older person can attest that aging muscles don't heal like young ones. But it turns out that's not the muscle's fault. A study in the Feb. 17 issue of Nature shows that it's old blood that keeps the muscles down. The study, led by Thomas Rando, MD, PhD, associate professor of neurology and neurological sciences at the Stanford University School of Medicine, built on previous work show...

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Scl at Biology Products

Interspecies Trial Array 2: N Brain, N Liver, N Muscle, N Kidney from CHEMICON

Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...
Company:CHEMICON

Human Skeletal Muscle RACE-Ready cDNA from Ambion

Description:...
Company:Ambion

C2C12 cell line slides ( mouse: muscle; myoblast ) from GeneTex

Description:Mouse C2C12 cells were cultured in DMEM and harvested at the log phase of growth. In order to keep the antigens in their native forms, cells were fixed in acetone-methanol. The cells are arrayed on a 12-well (5 mm) adhesive coated slide, with each wells surface specifically treated to enhance cellular attachment and to minimize background staining. Each well is loaded with approximately 7. 5 x...
Company:GeneTex

Rabbit Anti-Nonmuscle Myosin II Heavy Chain B (MHC-B) Polyclonal Antibody, Unconjugated from Covance Research Products, Inc

Description:Polyclonal Antibody against Nonmuscle Myosin II Heavy Chain Isoform B *Predicted MW = 200 kD....
Company:Covance Research Products, Inc

RayBio Mouse Atherosclerosis Antibody Array I & 1.1 Service from Raybiotech, Inc.

Description:Request Info...
Company:Raybiotech, Inc.

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Scl at Biology Technology

Primary cells, rat heart muscle

Primary cells: Adult heart muscle cells from rat, 6...

Laser Capture Microdissection (LCM) for the Analysis of Macrophage Gene Expression from Atherosclerotic Lesions

Macrophage foam cells are integral in the development of atherosclerotic lesions, however gene expression studies are complicated by the cellular heterogeneity of atherosclerotic plaque. This application note describes a protocol for LCM of cells identified immunohistochemi...

Laser Capture Microdissection of muscle fiber populations and expression analysis by RT-PCR

To locate gene products in distinct muscle fiber populations of different muscle allotypes, a novel protocol was established. A rapid method to distinguish muscle fiber types using histochemistry and...

Early Stage, Step 8: Misclassifying workers brings risk

- Wisconsin's unemployment insura...

Healthcare software addresses "90 million" misclassified Americans

Then imagine employers basing their health plan buying decisions on the often inaccurate information contained in that tool. Employers don't have to imagine such a scenario because they have been living it, unbeknown to them, for yea...

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Scl at Biology Definition

Muscle

and <a href="/ ?q=/ Biology-Definitio...

Malpighian corpuscle

. They are also known as: —...

Scl at Biology Dictionary

Voluntary muscle

: clusters of <a href="/ ?q=/ Biology-Diction...

Triceps muscle

and <a href="/ ?q=/ Biology-D...

Striated muscle

(or "voluntary"): attached to the <a href="/ ?q=/ ...

Smooth muscle

or "<a href="/ ?q=/ Biology-Dictionary/ involuntary_muscle" class="hiv"...

Skeletal muscle

and myoglobin, giving the <a href="/ ?q=/ Bio...

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Scl at Medicine News

Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis

A novel modification of a new technology born of genetic engineering, and known as naked DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The vaccine is currently being successfully tested in animals. In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, caus...

Antidepressants come in handy for patients on treatment for hepatitis, cancers and multiple sclerosis

The sad part in the treatment of certain cancers, hepatitis and multiple sclerosis with interferon therapy is that while the treatment can extent life, it can seriously spoil its quality. Alpha interferon a drug used to fight these diseases can cause crippling depression. A new research now shows that the use of an antidepressant before starting the treatment can avoid this problem. Al...

Half of world's children are passive smokers - damning disclosure from WHO

The world health organisation has come out with a damning disclosure that half the world's children are passive smoke. In a message on "No Tobacco Day 2001," World Health Organization chief Gro Harlem Brundtland said 700 million children were exposed to the health hazard because most governments still allowed smoking in public places. She added that scientists around the world agreed that...

Mushroom and muscle loss

According to a study in The New England Journal of Medicine, twelve people were hospitalized for severe weakness and muscle loss after eating the mushrooms, and three of them died, wrote Dr. Regis Bedry of the poison center of University Hospital Pellegrin in Bordeaux, France.Bedry said he confirmed the mushroom's toxicity by feeding extracts to mice and measuring creatine kinase, an enzy...

The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned

A recent study by Harvard researchers suggests a link between the hepatitis B vaccination and multiple sclerosis. In their study, people who received the vaccine were three-times more likely to develop MS // over the next three years than those who were not vaccinated. While this finding is disturbing, the investigators emphasize the overall effect of the vaccine on the development of MS...

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Scl at Medicine Products

Madlab Muscle Hook

Description:This device allows for quick and easy insertion of sutures during ophthalmic surgical procedures. The "Quick Hook" has an angled groove through which a suture may be passed into the eyelet during the loading procedure. The geometry of the groove prevents the suture from falling out unintentionally....
Company:Bausch & Lomb Storz

Culler Reclus Muscle Hook

Description:7 mm flattened hook. Flat serrated handle with polished finish. Overall length: 4.9 inches....
Company:Bausch & Lomb Storz

Scobee Oblique Muscle Hook

Description:Curved shaft with flat 4.5 mm hook. Flat serrated handle with polished finish. Overall length: 5.3 inches....
Company:Bausch & Lomb Storz

Jameson Muscle Hook

Description:2.0 mm bulbous tip with 6 mm flat portion. Flat serrated handle with polished finish. Overall length: 5.4 inches. Most popular size or model....
Company:Bausch & Lomb Storz

Jameson Muscle Hook - Small

Description:Small bulbous tip with flat sides. Flat serrated handle with polished finish. Overall length: 5.1 inches....
Company:Bausch & Lomb Storz

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Scl at Medicine Technology

Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis

THE WOODLANDS, Texas--(BUSINESS WIRE)--Jun 21, 2007 - OpexaTherapeutics, Inc. (NASDAQ:OPXA), a company involved in thedevelopment and commercialization of cell therapies, todayannounced positive top-line data in an open-label Phase I/IIextension clinical trial of the investigational T-cell vaccine,Tovaxin(TM), for multiple sclerosis (MS). In this one-year,8-subject extension clinical trial...

Orchestra Therapeutics Announces New Phase II Clinical Data on NeuroVax Demonstrating Marked Expansion of Regulatory T Cell Populations in Patients With Multiple Sclerosis

- New Data from Open-Label Study Presented at Federation ofClinical Immunology Societies (FOCIS) Annual Meeting - CARLSBAD, Calif., June 11, 2007 /PRNewswire-FirstCall/ --Orchestra Therapeutics, Inc. (Bulletin Board: OCHT) announced todaypositive new data from its completed Phase II open-label study ofNeuroVax(TM), an investigational T Cell Receptor (TCR) peptidevaccine for the treatment...

Annual Meeting of the Consortium of Multiple Sclerosis Centers Focuses on the Challenges of Care and Research in Multiple Sclerosis

WASHINGTON, June 01, 2007 /PRNewswire/ -- The annual meeting ofthe Consortium of Multiple Sclerosis Centers (CMSC), the largestmeeting devoted to the comprehensive care and science of multiplesclerosis (MS), is underway in the nation's capital today. Multiplesclerosis, a disease of the central nervous system that affects400,000 people in the United States, challenges patients, carepartne...

AEterna Zentaris' Partner, Spectrum, Discloses Detailed Phase 2 Data for Ozarelix, in BPH at Annual AUA Meeting

Ozarelix improved LUTS symptoms and urine flow over 28-week period QUEBEC CITY, May 23, 2007 /PRNewswire-FirstCall/ - AEternaZentaris Inc. , a global biopharmaceutical company focused onendocrine therapy and oncology, today announced that its partnerSpectrum Pharmaceuticals presented an abstract outlining detailedPhase 2 results for AEterna Zentaris' fourth-generation luteinizinghormone-r...

Accelreon Pharma's ACE-031Shown to Increase Muscle Mass in Preclinical Studies

LUCCA, ITALY, ­ May 14, 2007-Acceleron Pharma, Inc., abiopharmaceutical company developing therapeutics for the treatmentof musculoskeletal, metabolic and cancer-related diseases, todayannounced results of a preclinical study with ACE-031 thatdemonstrated the ability of the compound to increase muscle massand strength in normal mice and in murine models of musculardystrophy. ACE-031...

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Scl at Medicine Definition

Swank Multiple Sclerosis Diet

Dr Swank The Swank <a href="/ ?q=/ Medicine-Definition...

Muscle atrophy

<...

Scl at Medicine Dictionary

Tuberous sclerosis

on <a href="/ ?q=/ M...

Systemic sclerosis

characterized by changes in the <a hr...

Smooth muscle

options with your h...

Sclerosis

usually affects both ears, and is most commonly...

Sclerosing cholangitis

sclerosing cholangiti...

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